"Vitamin B 12 Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)
| Descriptor ID |
D014806
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| MeSH Number(s) |
C18.654.521.500.133.699.923
|
| Concept/Terms |
Vitamin B 12 Deficiency- Vitamin B 12 Deficiency
- Vitamin B12 Deficiency
- Deficiency, Vitamin B12
- Deficiencies, Vitamin B12
- Vitamin B12 Deficiencies
- Deficiency, Vitamin B 12
|
Below are MeSH descriptors whose meaning is more general than "Vitamin B 12 Deficiency".
Below are MeSH descriptors whose meaning is more specific than "Vitamin B 12 Deficiency".
This graph shows the total number of publications written about "Vitamin B 12 Deficiency" by people in this website by year, and whether "Vitamin B 12 Deficiency" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 3 | 0 | 3 |
| 2018 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Vitamin B 12 Deficiency" by people in Profiles.
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New genetic tools to define the pathophysiology of inborn errors of cobalamin metabolism impacting mammalian development. Differentiation. 2025 May-Jun; 143:100868.
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Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 01 10; 13(1):134.
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Pernicious anemia: Pathophysiology and diagnostic difficulties. J Evid Based Med. 2021 May; 14(2):161-169.
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Mouse models to study the pathophysiology of combined methylmalonic acidemia and homocystinuria, cblC type. Dev Biol. 2020 12 01; 468(1-2):1-13.
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The vitamin B12 processing enzyme, mmachc, is essential for zebrafish survival, growth and retinal morphology. Hum Mol Genet. 2020 08 03; 29(13):2109-2123.
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Weakness, Anemia, and Neutropenia in a 9-Year-Old Girl With Influenza. Pediatrics. 2020 04; 145(4).
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Megaloblastic Anemia Progressing to Severe Thrombotic Microangiopathy in Patients with Disordered Vitamin B12 Metabolism: Case Reports and Literature Review. J Pediatr. 2018 11; 202:315-319.e2.
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Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats. J Nutr. 2018 03 01; 148(3):358-363.
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The unusual nutritional and toxin-related underproduction anemias: approaching the riddle beyond iron, cobalamin, and folate. Discov Med. 2018 02; 25(136):67-74.
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Pernicious Anemia: Fundamental and Practical Aspects in Diagnosis. Cardiovasc Hematol Agents Med Chem. 2017 Nov 08; 15(1):17-22.