"Muscle Hypotonia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A diminution of the skeletal muscle tone marked by a diminished resistance to passive stretching.
| Descriptor ID |
D009123
|
| MeSH Number(s) |
C10.597.613.575 C23.888.592.608.575
|
| Concept/Terms |
Muscle Hypotonia- Muscle Hypotonia
- Hypotonia, Muscle
- Decreased Muscle Tone
- Muscle Tone, Decreased
- Muscle Tone Poor
- Tone Poor, Muscle
- Hypotonia
- Hypotony, Muscle
- Muscle Hypotony
- Muscular Hypotonia
- Hypotonia, Muscular
- Hypomyotonia
Neonatal Hypotonia- Neonatal Hypotonia
- Hypotonia, Neonatal
- Hypotonias, Neonatal
- Neonatal Hypotonias
Flaccid Muscle Tone- Flaccid Muscle Tone
- Muscle Tone, Flaccid
- Muscular Flaccidity
- Flaccidity, Muscular
- Muscular Flaccidities
- Muscle Flaccidity
- Flaccidity, Muscle
Floppy Muscles- Floppy Muscles
- Floppy Muscle
- Muscle, Floppy
- Muscles, Floppy
|
Below are MeSH descriptors whose meaning is more general than "Muscle Hypotonia".
Below are MeSH descriptors whose meaning is more specific than "Muscle Hypotonia".
This graph shows the total number of publications written about "Muscle Hypotonia" by people in this website by year, and whether "Muscle Hypotonia" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2005 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 3 | 4 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 5 | 6 | 11 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 2 | 3 |
| 2019 | 2 | 2 | 4 |
| 2020 | 1 | 4 | 5 |
| 2021 | 1 | 3 | 4 |
| 2022 | 2 | 6 | 8 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "Muscle Hypotonia" by people in Profiles.
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MED12 Loss-of-Function Variants as a Cause of Congenital Diaphragmatic Hernia in Females With Hardikar Syndrome and Nonspecific Intellectual Disability. Am J Med Genet A. 2025 Jan; 197(1):e63868.
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Laryngeal clefts in Prader-Willi syndrome: Feeding difficulties and aspiration not always caused by hypotonia. Am J Med Genet A. 2024 08; 194(8):e63634.
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Expanded clinical phenotype and untargeted metabolomics analysis in RARS2-related mitochondrial disorder: a case report. BMC Neurol. 2024 Mar 04; 24(1):87.
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De novo missense variants in ZBTB47 are associated with developmental delays, hypotonia, seizures, gait abnormalities, and variable movement abnormalities. Am J Med Genet A. 2024 01; 194(1):17-30.
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Heterozygous rare variants in NR2F2 cause a recognizable multiple congenital anomaly syndrome with developmental delays. Eur J Hum Genet. 2023 10; 31(10):1117-1124.
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Rare EIF4A2 variants are associated with a neurodevelopmental disorder characterized by intellectual disability, hypotonia, and epilepsy. Am J Hum Genet. 2023 01 05; 110(1):120-145.
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TCEAL1 loss-of-function results in an X-linked dominant neurodevelopmental syndrome and drives the neurological disease trait in Xq22.2 deletions. Am J Hum Genet. 2022 12 01; 109(12):2270-2282.
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A recurrent single-exon deletion in TBCK might be under-recognized in patients with infantile hypotonia and psychomotor delay. Hum Mutat. 2022 12; 43(12):1816-1823.
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Gain and loss of TASK3 channel function and its regulation by novel variation cause KCNK9 imprinting syndrome. Genome Med. 2022 06 13; 14(1):62.
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Complex effects on CaV2.1 channel gating caused by a CACNA1A variant associated with a severe neurodevelopmental disorder. Sci Rep. 2022 06 02; 12(1):9186.