"Exodeoxyribonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of enzymes that catalyze the exonucleolytic cleavage of DNA. It includes members of the class EC 3.1.11 that produce 5'-phosphomonoesters as cleavage products.
| Descriptor ID |
D005090
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| MeSH Number(s) |
D08.811.277.352.335.375 D08.811.277.352.365.290
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Exodeoxyribonucleases".
Below are MeSH descriptors whose meaning is more specific than "Exodeoxyribonucleases".
This graph shows the total number of publications written about "Exodeoxyribonucleases" by people in this website by year, and whether "Exodeoxyribonucleases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 3 | 0 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 3 | 0 | 3 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 2 | 3 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Exodeoxyribonucleases" by people in Profiles.
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The DNase TREX1 is a substrate of the intramembrane protease SPP with implications for disease pathogenesis. Cell Mol Life Sci. 2025 Mar 12; 82(1):107.
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RPA and Rad27 limit templated and inverted insertions at DNA breaks. Nucleic Acids Res. 2025 Jan 07; 53(1).
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Systemic complications of Aicardi Gouti?res syndrome using real-world data. Mol Genet Metab. 2024 Sep-Oct; 143(1-2):108578.
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A Rad51-independent pathway promotes single-strand template repair in gene editing. PLoS Genet. 2020 10; 16(10):e1008689.
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Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast. Mol Cell. 2019 12 05; 76(5):699-711.e6.
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MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells. Nat Commun. 2017 10 16; 8(1):860.
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Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice. J Immunol. 2015 Nov 15; 195(10):4573-7.
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T. rex attacks the lysosome. Nat Immunol. 2013 Jan; 14(1):10-2.
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The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1. EMBO J. 2013 Jan 09; 32(1):126-39.
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The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends. Nature. 2012 Sep 27; 489(7417):576-80.