"Receptor, Muscarinic M2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-containing organs. Although present in smooth muscle the M2 muscarinic receptor appears not to be involved in contractile responses.
| Descriptor ID |
D043585
|
| MeSH Number(s) |
D12.776.543.750.695.475.200 D12.776.543.750.720.360.500.200
|
| Concept/Terms |
Receptor, Muscarinic M2- Receptor, Muscarinic M2
- M2 Receptor, Muscarinic
- Muscarinic M2 Receptor
- Receptors, Muscarinic M2
- M2 Receptors, Muscarinic
- Muscarinic M2 Receptors
- Muscarinic Receptor M2
- M2, Muscarinic Receptor
- Receptor M2, Muscarinic
- Muscarinic Receptors M2
- M2, Muscarinic Receptors
- Receptors M2, Muscarinic
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Muscarinic M2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Muscarinic [D12.776.543.750.695.475]
- Receptor, Muscarinic M2 [D12.776.543.750.695.475.200]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Muscarinic [D12.776.543.750.720.360.500]
- Receptor, Muscarinic M2 [D12.776.543.750.720.360.500.200]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Muscarinic M2".
This graph shows the total number of publications written about "Receptor, Muscarinic M2" by people in this website by year, and whether "Receptor, Muscarinic M2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 3 | 0 | 3 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Receptor, Muscarinic M2" by people in Profiles.
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Regulating nociceptive transmission by VGluT2-expressing spinal dorsal horn neurons. J Neurochem. 2018 11; 147(4):526-540.
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RE1-silencing transcription factor controls the acute-to-chronic neuropathic pain transition and Chrm2 receptor gene expression in primary sensory neurons. J Biol Chem. 2018 12 07; 293(49):19078-19091.
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Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats. J Neurochem. 2009 Nov; 111(4):1000-10.
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Transcriptional up-regulation of nitric oxide synthase II by nuclear factor-kappaB at rostral ventrolateral medulla in a rat mevinphos intoxication model of brain stem death. J Physiol. 2007 Jun 15; 581(Pt 3):1293-307.
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Regulation of glutamate release from primary afferents and interneurons in the spinal cord by muscarinic receptor subtypes. J Neurophysiol. 2007 Jan; 97(1):102-9.
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Dynamic regulation of glycinergic input to spinal dorsal horn neurones by muscarinic receptor subtypes in rats. J Physiol. 2006 Mar 01; 571(Pt 2):403-13.
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Opposing functions of spinal M2, M3, and M4 receptor subtypes in regulation of GABAergic inputs to dorsal horn neurons revealed by muscarinic receptor knockout mice. Mol Pharmacol. 2006 Mar; 69(3):1048-55.
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Functional activity of the M2 and M4 receptor subtypes in the spinal cord studied with muscarinic acetylcholine receptor knockout mice. J Pharmacol Exp Ther. 2005 May; 313(2):765-70.
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M2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons. J Pharmacol Exp Ther. 2005 May; 313(2):697-704.
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Muscarinic subtype-2 receptor autoantibodies: actors or bystanders in human atrial fibrillation? Eur Heart J. 2004 Jul; 25(13):1091-2.