"Receptor, Muscarinic M1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific subtype of muscarinic receptor that has a high affinity for the drug PIRENZEPINE. It is found in the peripheral GANGLIA where it signals a variety of physiological functions such as GASTRIC ACID secretion and BRONCHOCONSTRICTION. This subtype of muscarinic receptor is also found in neuronal tissues including the CEREBRAL CORTEX and HIPPOCAMPUS where it mediates the process of MEMORY and LEARNING.
| Descriptor ID |
D043643
|
| MeSH Number(s) |
D12.776.543.750.695.475.100 D12.776.543.750.720.360.500.099
|
| Concept/Terms |
Receptor, Muscarinic M1- Receptor, Muscarinic M1
- M1 Receptor, Muscarinic
- Muscarinic M1 Receptor
- Receptors, Muscarinic M1
- M1 Receptors, Muscarinic
- Muscarinic M1 Receptors
- Muscarinic Receptor M1
- M1, Muscarinic Receptor
- Receptor M1, Muscarinic
- Muscarinic Receptors M1
- M1, Muscarinic Receptors
- Receptors M1, Muscarinic
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Muscarinic M1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Muscarinic [D12.776.543.750.695.475]
- Receptor, Muscarinic M1 [D12.776.543.750.695.475.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Muscarinic [D12.776.543.750.720.360.500]
- Receptor, Muscarinic M1 [D12.776.543.750.720.360.500.099]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Muscarinic M1".
This graph shows the total number of publications written about "Receptor, Muscarinic M1" by people in this website by year, and whether "Receptor, Muscarinic M1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Muscarinic M1" by people in Profiles.
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Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects. Epigenetics. 2022 Jan-Feb; 17(2):133-146.
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Muscarinic type-1 receptors contribute to IK,ACh in human atrial cardiomyocytes and are upregulated in patients with chronic atrial fibrillation. Int J Cardiol. 2018 Mar 15; 255:61-68.
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Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells. Neuron. 2015 Jan 21; 85(2):346-63.
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Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome. Psychopharmacology (Berl). 2011 Sep; 217(1):143-51.
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Muscarinic m1 and m2 receptor proteins in local circuit and projection neurons of the primate striatum: anatomical evidence for cholinergic modulation of glutamatergic prefronto-striatal pathways. J Comp Neurol. 2001 Jun 11; 434(4):445-60.