"Receptor, Muscarinic M4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific subtype of muscarinic receptor found in the CORPUS STRIATUM and the LUNG. It has similar receptor binding specificities to MUSCARINIC RECEPTOR M1 and MUSCARINIC RECEPTOR M2.
| Descriptor ID |
D043588
|
| MeSH Number(s) |
D12.776.543.750.695.475.400 D12.776.543.750.720.360.500.400
|
| Concept/Terms |
Receptor, Muscarinic M4- Receptor, Muscarinic M4
- M4 Receptor, Muscarinic
- Muscarinic M4 Receptor
- Receptors, Muscarinic M4
- M4 Receptors, Muscarinic
- Muscarinic M4 Receptors
- Muscarinic Receptor M4
- M4, Muscarinic Receptor
- Receptor M4, Muscarinic
- Muscarinic Receptors M4
- M4, Muscarinic Receptors
- Receptors M4, Muscarinic
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Muscarinic M4".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Muscarinic [D12.776.543.750.695.475]
- Receptor, Muscarinic M4 [D12.776.543.750.695.475.400]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Muscarinic [D12.776.543.750.720.360.500]
- Receptor, Muscarinic M4 [D12.776.543.750.720.360.500.400]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Muscarinic M4".
This graph shows the total number of publications written about "Receptor, Muscarinic M4" by people in this website by year, and whether "Receptor, Muscarinic M4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 3 | 0 | 3 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
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Below are the most recent publications written about "Receptor, Muscarinic M4" by people in Profiles.
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Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS). Behav Brain Res. 2012 Mar 01; 228(1):1-8.
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The modulation of fragile X behaviors by the muscarinic M4 antagonist, tropicamide. Behav Neurosci. 2011 Oct; 125(5):783-90.
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Diabetic neuropathy enhances voltage-activated Ca2+ channel activity and its control by M4 muscarinic receptors in primary sensory neurons. J Neurochem. 2011 Nov; 119(3):594-603.
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Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats. J Neurochem. 2009 Nov; 111(4):1000-10.
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Transcriptional up-regulation of nitric oxide synthase II by nuclear factor-kappaB at rostral ventrolateral medulla in a rat mevinphos intoxication model of brain stem death. J Physiol. 2007 Jun 15; 581(Pt 3):1293-307.
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Regulation of glutamate release from primary afferents and interneurons in the spinal cord by muscarinic receptor subtypes. J Neurophysiol. 2007 Jan; 97(1):102-9.
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Dynamic regulation of glycinergic input to spinal dorsal horn neurones by muscarinic receptor subtypes in rats. J Physiol. 2006 Mar 01; 571(Pt 2):403-13.
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Opposing functions of spinal M2, M3, and M4 receptor subtypes in regulation of GABAergic inputs to dorsal horn neurons revealed by muscarinic receptor knockout mice. Mol Pharmacol. 2006 Mar; 69(3):1048-55.
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Functional activity of the M2 and M4 receptor subtypes in the spinal cord studied with muscarinic acetylcholine receptor knockout mice. J Pharmacol Exp Ther. 2005 May; 313(2):765-70.
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M2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons. J Pharmacol Exp Ther. 2005 May; 313(2):697-704.