"Cerebroside-Sulfatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.
| Descriptor ID |
D002553
|
| MeSH Number(s) |
D08.811.277.352.827.070.250
|
| Concept/Terms |
Cerebroside-Sulfatase- Cerebroside-Sulfatase
- Cerebroside Sulfatase
- Sulfatidate Sulfatase
- Sulfatase, Sulfatidate
- Arylsulfatase A
|
Below are MeSH descriptors whose meaning is more general than "Cerebroside-Sulfatase".
Below are MeSH descriptors whose meaning is more specific than "Cerebroside-Sulfatase".
This graph shows the total number of publications written about "Cerebroside-Sulfatase" by people in this website by year, and whether "Cerebroside-Sulfatase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cerebroside-Sulfatase" by people in Profiles.
-
Exploring the effect of disease causing mutations in metal binding sites of human ARSA in metachromatic leukodystrophy. Adv Protein Chem Struct Biol. 2024; 141:203-221.
-
Consensus guidelines for the monitoring and management of metachromatic leukodystrophy in the United States. Cytotherapy. 2024 Jul; 26(7):739-748.
-
Effect of an anti-sulfatide single-chain antibody probe on platelet function. Thromb Haemost. 2008 Mar; 99(3):552-7.
-
Safety of arylsulfatase A overexpression for gene therapy of metachromatic leukodystrophy. Hum Gene Ther. 2007 Sep; 18(9):821-36.
-
A novel arylsulfatase A protein variant and genotype in two patients with major depression. J Affect Disord. 1996 Oct 14; 40(3):137-47.
-
Leukocyte arylsulphatase A activity in acute leukemia. Cancer Biochem Biophys. 1994 Apr; 14(1):53-6.
-
Prenatal diagnosis of mucolipidosis type II on first-trimester amniotic fluid. Prenat Diagn. 1990 Apr; 10(4):231-5.
-
First trimester prenatal diagnosis of metachromatic leukodystrophy on chorionic villi by 'immunoprecipitation-electrophoresis'. J Inherit Metab Dis. 1988; 11(2):123-30.