Retinoblastoma-Binding Protein 1
"Retinoblastoma-Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed regulatory protein that contains a retinoblastoma protein binding domain and an AT-rich interactive domain. The protein may play a role in recruiting HISTONE DEACETYLASES to the site of RETINOBLASTOMA PROTEIN-containing transcriptional repressor complexes.
| Descriptor ID |
D056465
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| MeSH Number(s) |
D12.644.360.024.328.100 D12.776.157.057.158.100 D12.776.476.024.420.100 D12.776.660.769.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinoblastoma-Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma-Binding Protein 1".
This graph shows the total number of publications written about "Retinoblastoma-Binding Protein 1" by people in this website by year, and whether "Retinoblastoma-Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinoblastoma-Binding Protein 1" by people in Profiles.
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ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4616-21.
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Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes. J Natl Cancer Inst. 2008 Sep 03; 100(17):1247-59.
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Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain. Genes Dev. 2006 Oct 15; 20(20):2859-70.
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Alterations of p14ARF, p53, and p73 genes involved in the E2F-1-mediated apoptotic pathways in non-small cell lung carcinoma. Cancer Res. 2001 Jul 15; 61(14):5636-43.
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p19ARF targets certain E2F species for degradation. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4455-60.
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Cyclin D1 and E2F-1 immunoreactivity in bone marrow biopsy specimens of multiple myeloma: relationship to proliferative activity, cytogenetic abnormalities and DNA ploidy. Br J Haematol. 2001 Mar; 112(3):776-82.
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DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation. Nat Cell Biol. 2001 Jan; 3(1):1-7.
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Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2. Invest Ophthalmol Vis Sci. 2000 Dec; 41(13):4223-31.
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E2F-1 gene transfer enhances invasiveness of human head and neck carcinoma cell lines. Cancer Res. 2000 Nov 01; 60(21):5972-6.
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E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo. Mol Cell Biol. 2000 May; 20(10):3417-24.