Retinoblastoma-Binding Protein 1
"Retinoblastoma-Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed regulatory protein that contains a retinoblastoma protein binding domain and an AT-rich interactive domain. The protein may play a role in recruiting HISTONE DEACETYLASES to the site of RETINOBLASTOMA PROTEIN-containing transcriptional repressor complexes.
| Descriptor ID |
D056465
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| MeSH Number(s) |
D12.644.360.024.328.100 D12.776.157.057.158.100 D12.776.476.024.420.100 D12.776.660.769.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinoblastoma-Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma-Binding Protein 1".
This graph shows the total number of publications written about "Retinoblastoma-Binding Protein 1" by people in this website by year, and whether "Retinoblastoma-Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Retinoblastoma-Binding Protein 1" by people in Profiles.
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Cyclin D1 and E2F-1 immunoreactivity in bone marrow biopsy specimens of multiple myeloma: relationship to proliferative activity, cytogenetic abnormalities and DNA ploidy. Br J Haematol. 2001 Mar; 112(3):776-82.
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Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2. Invest Ophthalmol Vis Sci. 2000 Dec; 41(13):4223-31.
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E2F-1 gene transfer enhances invasiveness of human head and neck carcinoma cell lines. Cancer Res. 2000 Nov 01; 60(21):5972-6.
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E2F4 and E2F1 have similar proliferative properties but different apoptotic and oncogenic properties in vivo. Mol Cell Biol. 2000 May; 20(10):3417-24.
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The paradox of E2F1: oncogene and tumor suppressor gene. Mol Carcinog. 2000 Mar; 27(3):151-7.
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Stable expression of a dominant negative mutant of CCAAT binding factor/NF-Y in mouse fibroblast cells resulting in retardation of cell growth and inhibition of transcription of various cellular genes. J Biol Chem. 2000 Feb 11; 275(6):4435-44.
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Regulation of BRCA1 expression by the Rb-E2F pathway. J Biol Chem. 2000 Feb 11; 275(6):4532-6.
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Differential regulation of E2F transcription factors by p53 tumor suppressor protein. DNA Cell Biol. 1999 Dec; 18(12):911-22.
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E2F1 has both oncogenic and tumor-suppressive properties in a transgenic model. Mol Cell Biol. 1999 Sep; 19(9):6408-14.
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E2F/p107 and E2F/p130 complexes are regulated by C/EBPalpha in 3T3-L1 adipocytes. Nucleic Acids Res. 1999 Sep 01; 27(17):3621-30.