"Sp4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specificity protein transcription factor that is expressed primarily in the CENTRAL NERVOUS SYSTEM.
| Descriptor ID |
D051706
|
| MeSH Number(s) |
D12.776.260.522.750.875 D12.776.930.375.750.875
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sp4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "Sp4 Transcription Factor".
This graph shows the total number of publications written about "Sp4 Transcription Factor" by people in this website by year, and whether "Sp4 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sp4 Transcription Factor" by people in Profiles.
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Neuron-specific specificity protein 4 bigenomically regulates the transcription of all mitochondria- and nucleus-encoded cytochrome c oxidase subunit genes in neurons. J Neurochem. 2013 Nov; 127(4):496-508.
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Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes. Oncotarget. 2010 Aug; 1(4):246-51.
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Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1alpha/Sp4. Mol Cancer Ther. 2009 Dec; 8(12):3223-33.
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Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. Cancer Res. 2007 Apr 01; 67(7):3286-94.
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Sp4 is expressed in retinal neurons, activates transcription of photoreceptor-specific genes, and synergizes with Crx. J Biol Chem. 2005 May 27; 280(21):20642-50.