"Colforsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant COLEUS FORSKOHLII. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.
| Descriptor ID |
D005576
|
| MeSH Number(s) |
D02.455.849.291.300
|
| Concept/Terms |
Colforsin- Colforsin
- N,N-Dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl Ester HCl
- Coleonol
- Forskolin
|
Below are MeSH descriptors whose meaning is more general than "Colforsin".
Below are MeSH descriptors whose meaning is more specific than "Colforsin".
This graph shows the total number of publications written about "Colforsin" by people in this website by year, and whether "Colforsin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 4 | 4 |
| 1997 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 2 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 4 | 4 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 2 | 2 |
| 2012 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Colforsin" by people in Profiles.
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Mechanisms of cyclic AMP/protein kinase A- and glucocorticoid-mediated apoptosis using S49 lymphoma cells as a model system. Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41):12681-6.
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A mutation in CLOCK leads to altered dopamine receptor function. J Neurochem. 2012 Oct; 123(1):124-34.
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Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells. Mol Endocrinol. 2012 Oct; 26(10):1732-42.
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Targeted disruption of Mapk14 (p38MAPKalpha) in granulosa cells and cumulus cells causes cell-specific changes in gene expression profiles that rescue COC expansion and maintain fertility. Mol Endocrinol. 2010 Sep; 24(9):1794-804.
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The nuclear receptor cofactor receptor-interacting protein 140 is a positive regulator of amphiregulin expression and cumulus cell-oocyte complex expansion in the mouse ovary. Endocrinology. 2010 Jun; 151(6):2923-32.
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Steroid receptor coactivator-1 is necessary for regulation of corticotropin-releasing hormone by chronic stress and glucocorticoids. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):8038-42.
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Interleukin-6 induces proinflammatory signaling in Schwann cells: a high-throughput analysis. Biochem Biophys Res Commun. 2009 May 01; 382(2):410-4.
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APC sensitive gastric acid secretion. Cell Physiol Biochem. 2009; 23(1-3):133-42.
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Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice. J Clin Invest. 2009 Mar; 119(3):540-50.
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Role of PDK1 in regulation of gastric acid secretion. Cell Physiol Biochem. 2008; 22(5-6):725-34.