"Retinoid X Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of RETINOIC ACID RECEPTORS that are specific for 9-cis-retinoic acid which function as nuclear TRANSCRIPTION FACTORS that regulate multiple signaling pathways.
| Descriptor ID |
D047488
|
| MeSH Number(s) |
D12.776.826.701.500 D12.776.930.775.500
|
| Concept/Terms |
Retinoid X Receptors- Retinoid X Receptors
- Receptors, Retinoid X
- RXR Protein
- Protein, RXR
- Retinoid X Receptor
- 9-cis-Retinoic Acid Receptor
- Receptor, 9-cis-Retinoic Acid
- Receptor, Retinoid X
|
Below are MeSH descriptors whose meaning is more general than "Retinoid X Receptors".
Below are MeSH descriptors whose meaning is more specific than "Retinoid X Receptors".
This graph shows the total number of publications written about "Retinoid X Receptors" by people in this website by year, and whether "Retinoid X Receptors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 6 | 7 |
| 2005 | 2 | 1 | 3 |
| 2006 | 1 | 0 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Retinoid X Receptors" by people in Profiles.
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Bexarotene normalizes chemotherapy-induced myelin decompaction and reverses cognitive and sensorimotor deficits in mice. Acta Neuropathol Commun. 2020 11 12; 8(1):193.
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Heterodimerization of Retinoid X Receptor with Xenobiotic Receptor partners occurs in the cytoplasmic compartment: Mechanistic insights of events in living cells. Exp Cell Res. 2017 11 15; 360(2):337-346.
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Retinoids and rexinoids in cancer prevention: from laboratory to clinic. Semin Oncol. 2016 Feb; 43(1):49-64.
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Bexarotene reduces network excitability in models of Alzheimer's disease and epilepsy. Neurobiol Aging. 2014 Sep; 35(9):2091-5.
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Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalpha-dependent manner. J Biol Chem. 2010 May 07; 285(19):14078-82.
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Combined low doses of PPARgamma and RXR ligands trigger an intrinsic apoptotic pathway in human breast cancer cells. Am J Pathol. 2009 Sep; 175(3):1270-80.
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The thyroid hormone receptor recruits NCoR via widely spaced receptor-interacting domains. Mol Cell Endocrinol. 2009 Aug 13; 307(1-2):83-8.
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Pharmacological manipulation of the RAR/RXR signaling pathway maintains the repopulating capacity of hematopoietic stem cells in culture. Mol Endocrinol. 2009 Feb; 23(2):188-201.
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UBE1L causes lung cancer growth suppression by targeting cyclin D1. Mol Cancer Ther. 2008 Dec; 7(12):3780-8.
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Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid. Cancer Prev Res (Phila). 2008 Aug; 1(3):208-14.