Retinoid X Receptor alpha
"Retinoid X Receptor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear transcription factor. Heterodimerization with PPAR GAMMA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES.
| Descriptor ID |
D047490
|
| MeSH Number(s) |
D12.776.826.701.500.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinoid X Receptor alpha".
Below are MeSH descriptors whose meaning is more specific than "Retinoid X Receptor alpha".
This graph shows the total number of publications written about "Retinoid X Receptor alpha" by people in this website by year, and whether "Retinoid X Receptor alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 3 | 0 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Retinoid X Receptor alpha" by people in Profiles.
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Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells. PLoS One. 2019; 14(11):e0224405.
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Silencing carboxylesterase 1 in human THP-1 macrophages perturbs genes regulated by PPAR?/RXR and RAR/RXR: down-regulation of CYP27A1-LXRa signaling. Biochem J. 2018 02 09; 475(3):621-642.
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Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation. Elife. 2017 11 16; 6.
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Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA. Structure. 2017 10 03; 25(10):1506-1518.e4.
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Novel Application of Red Fluorescent Protein (DsRed-Express) for the Study of Functional Dynamics of Nuclear Receptors. J Fluoresc. 2017 Jul; 27(4):1225-1231.
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Genetic variants in the vitamin D pathway genes VDBP and RXRA modulate cutaneous melanoma disease-specific survival. Pigment Cell Melanoma Res. 2016 Mar; 29(2):176-85.
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Up-regulation of steroid biosynthesis by retinoid signaling: Implications for aging. Mech Ageing Dev. 2015 Sep; 150:74-82.
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Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. Nat Commun. 2015 Aug 20; 6:8013.
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Impaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRa variant lacking the DNA-binding domain. J Hepatol. 2014 Feb; 60(2):362-9.
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Influence of PPARA, RXRA, NR1I2 and NR1I3 gene polymorphisms on the lipid-lowering efficacy and safety of statin therapy. Arq Bras Endocrinol Metabol. 2013 Oct; 57(7):513-9.