Retinoic Acid Receptor alpha
"Retinoic Acid Receptor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear receptor protein which belongs to a family of transcription regulators of ligand-responsive regulatory proteins which include steroid hormone receptors. In addition to a C-terminal ligand-binding domain, these nuclear receptors contain a highly-conserved N-terminal zinc-finger domain that mediates binding ligand-responsive elements.
| Descriptor ID |
D000072482
|
| MeSH Number(s) |
D12.776.826.701.250 D12.776.930.775.250
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Retinoic Acid Receptor alpha".
Below are MeSH descriptors whose meaning is more specific than "Retinoic Acid Receptor alpha".
This graph shows the total number of publications written about "Retinoic Acid Receptor alpha" by people in this website by year, and whether "Retinoic Acid Receptor alpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 3 | 3 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Retinoic Acid Receptor alpha" by people in Profiles.
-
Acute promyelocytic leukemia (APL) with an IRF2BP2-RARA fusion transcript: an aggressive APL variant. Leuk Lymphoma. 2020 12; 61(12):3018-3020.
-
Estrogen receptor a (ERa)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice. J Biol Chem. 2020 06 19; 295(25):8387-8400.
-
Dissecting the novel partners of nuclear c-Raf and its role in all-trans retinoic acid (ATRA)-induced myeloblastic leukemia cells differentiation. Exp Cell Res. 2020 09 01; 394(1):111989.
-
Up-regulation of steroid biosynthesis by retinoid signaling: Implications for aging. Mech Ageing Dev. 2015 Sep; 150:74-82.
-
Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells. J Biol Chem. 2015 Apr 24; 290(17):10599-609.
-
Identification of a novel fusion gene, IRF2BP2-RARA, in acute promyelocytic leukemia. J Natl Compr Canc Netw. 2015 Jan; 13(1):19-22.
-
Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration. Blood. 2013 Sep 19; 122(12):2125-34.
-
Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure. Kidney Int. 2012 May; 81(9):856-64.
-
Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. JAMA. 2011 Apr 20; 305(15):1577-84.
-
The self-association coiled-coil domain of PML is sufficient for the oncogenic conversion of the retinoic acid receptor (RAR) alpha. Leukemia. 2011 May; 25(5):814-20.