Cyclin-Dependent Kinase Inhibitor p18
"Cyclin-Dependent Kinase Inhibitor p18" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An INK4 cyclin-dependent kinase inhibitor containing five ANKYRIN-LIKE REPEATS. Aberrant expression of this protein has been associated with deregulated EPITHELIAL CELL growth, organ enlargement, and a variety of NEOPLASMS.
| Descriptor ID |
D050763
|
| MeSH Number(s) |
D12.644.360.225.300 D12.776.167.187.300 D12.776.476.225.300 D12.776.624.776.355.300
|
| Concept/Terms |
Cyclin-Dependent Kinase Inhibitor p18- Cyclin-Dependent Kinase Inhibitor p18
- Cyclin Dependent Kinase Inhibitor p18
- p18 CDK6 Inhibitor
- CDK6 Inhibitor, p18
- CDK6-Associated Protein p18
- CDK6 Associated Protein p18
- p18, CDK6-Associated Protein
- p18INK4c Protein
- Cyclin-Dependent Kinase Inhibitor 2C
- Cyclin Dependent Kinase Inhibitor 2C
- INK4C Protein
- CDKN2C Protein
|
Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase Inhibitor p18".
Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase Inhibitor p18".
This graph shows the total number of publications written about "Cyclin-Dependent Kinase Inhibitor p18" by people in this website by year, and whether "Cyclin-Dependent Kinase Inhibitor p18" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
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Below are the most recent publications written about "Cyclin-Dependent Kinase Inhibitor p18" by people in Profiles.
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Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability. Cell Death Dis. 2019 03 20; 10(4):271.
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Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci Rep. 2015 Dec 18; 5:18115.
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Small-molecule inhibitors targeting INK4 protein p18(INK4C) enhance ex vivo expansion of haematopoietic stem cells. Nat Commun. 2015 Feb 18; 6:6328.
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Upregulation of p18Ink4c expression by oncogenic HPV E6 via p53-miR-34a pathway. Int J Cancer. 2011 Sep 15; 129(6):1362-72.
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Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development. Cancer Cell. 2008 Apr; 13(4):355-64.