Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency.

Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency. J Immunol. 2013 Apr 01; 190(7):3732-9.

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subject areas

Amino Acid Sequence
Antibodies, Monoclonal
Antibodies, Neutralizing
Antibodies, Viral
Antibody Affinity
Antibody Specificity
Humans
Immunoglobulin Fab Fragments
Immunoglobulin Variable Region
Kinetics
Models, Molecular
Molecular Docking Simulation
Mutation
Neutralization Tests
Protein Binding
Protein Conformation
Recombinant Proteins
Respiratory Syncytial Virus, Human
Viral Fusion Proteins

authors with profiles

JAMES CROWE