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Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy.
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Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy.
Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy. Cancer Immunol Res. 2013 Oct; 1(4):229-34.
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PubMed
subject areas
Antibodies, Monoclonal
Biomarkers
CD4-Positive T-Lymphocytes
CTLA-4 Antigen
Cytokines
Flow Cytometry
Healthy Volunteers
Humans
Inducible T-Cell Co-Stimulator Protein
Ipilimumab
Lymphocyte Activation
Melanoma
Randomized Controlled Trials as Topic
Sensitivity and Specificity
Vaccines, DNA
authors with profiles
JAMES P ALLISON
PADMANEE SHARMA