"Vaccines, DNA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.
Descriptor ID |
D019444
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MeSH Number(s) |
D12.776.828.868.910 D20.215.894.865.910 D23.050.865.910
|
Concept/Terms |
Vaccines, DNA- Vaccines, DNA
- Recombinant DNA Vaccines
- DNA Vaccines, Recombinant
- DNA Vaccines
- Naked DNA Vaccines
- DNA Vaccines, Naked
- Vaccines, Naked DNA
- Vaccines, Recombinant DNA
|
Below are MeSH descriptors whose meaning is more general than "Vaccines, DNA".
Below are MeSH descriptors whose meaning is more specific than "Vaccines, DNA".
This graph shows the total number of publications written about "Vaccines, DNA" by people in this website by year, and whether "Vaccines, DNA" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 |
1998 | 1 | 0 | 1 |
1999 | 1 | 1 | 2 |
2000 | 2 | 0 | 2 |
2001 | 1 | 0 | 1 |
2002 | 0 | 2 | 2 |
2003 | 2 | 4 | 6 |
2004 | 0 | 2 | 2 |
2005 | 6 | 2 | 8 |
2006 | 6 | 0 | 6 |
2007 | 2 | 2 | 4 |
2008 | 5 | 1 | 6 |
2009 | 5 | 2 | 7 |
2010 | 0 | 2 | 2 |
2011 | 4 | 2 | 6 |
2012 | 1 | 1 | 2 |
2013 | 0 | 4 | 4 |
2014 | 3 | 0 | 3 |
2015 | 1 | 0 | 1 |
2016 | 2 | 1 | 3 |
2017 | 1 | 1 | 2 |
2018 | 2 | 0 | 2 |
2019 | 1 | 0 | 1 |
2020 | 4 | 1 | 5 |
2021 | 1 | 1 | 2 |
2022 | 1 | 0 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Vaccines, DNA" by people in Profiles.
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The next-generation DNA vaccine platforms and delivery systems: advances, challenges and prospects. Front Immunol. 2024; 15:1332939.
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Vaccine-linked chemotherapy with a low dose of benznidazole plus a bivalent recombinant protein vaccine prevents the development of cardiac fibrosis caused by Trypanosoma cruzi in chronically-infected BALB/c mice. PLoS Negl Trop Dis. 2022 09; 16(9):e0010258.
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Human Antibody Responses Following Vaccinia Immunization Using Protein Microarrays and Correlation With Cell-Mediated Immunity and Antibody-Dependent Cellular Cytotoxicity Responses. J Infect Dis. 2021 10 28; 224(8):1372-1382.
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Safe and effective aerosolization of in vitro transcribed mRNA to the respiratory tract epithelium of horses without a transfection agent. Sci Rep. 2021 01 11; 11(1):371.
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Complete protection for mice conferred by a DNA vaccine based on the Japanese encephalitis virus P3 strain used to prepare the inactivated vaccine in China. Virol J. 2020 08 24; 17(1):126.
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Immune responses and protective effects against Japanese encephalitis induced by a DNA vaccine encoding the prM/E proteins of the attenuated SA14-14-2 strain. Infect Genet Evol. 2020 11; 85:104443.
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Multi-antigen DNA vaccine delivered by polyethylenimine and Salmonella enterica in neuroblastoma mouse model. Cancer Immunol Immunother. 2020 Dec; 69(12):2613-2622.
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The Brighton Collaboration standardized template for collection of key information for benefit-risk assessment of nucleic acid (RNA and DNA) vaccines. Vaccine. 2020 07 22; 38(34):5556-5561.
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Conjugation of new DNA vaccine with polyethylenimine induces cellular immune response and tumor regression in neuroblastoma mouse model. Exp Oncol. 2020 06; 42(2):120-125.
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Safety and immunogenicity of investigational seasonal influenza hemagglutinin DNA vaccine followed by trivalent inactivated vaccine administered intradermally or intramuscularly in healthy adults: An open-label randomized phase 1 clinical trial. PLoS One. 2019; 14(9):e0222178.