FoxO3 transcription factor and Sirt6 deacetylase regulate low density lipoprotein (LDL)-cholesterol homeostasis via control of the proprotein convertase subtilisin/kexin type 9 (Pcsk9) gene expression.

FoxO3 transcription factor and Sirt6 deacetylase regulate low density lipoprotein (LDL)-cholesterol homeostasis via control of the proprotein convertase subtilisin/kexin type 9 (Pcsk9) gene expression. J Biol Chem. 2013 Oct 11; 288(41):29252-9.

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subject areas

Acetylation
Animals
Blotting, Western
Cholesterol, LDL
Forkhead Box Protein O3
Forkhead Transcription Factors
Gene Expression Regulation
Histones
Homeostasis
Liver
Lysine
Mice
Mice, 129 Strain
Mice, Inbred C57BL
Mice, Knockout
Promoter Regions, Genetic
Proprotein Convertase 9
Proprotein Convertases
Reverse Transcriptase Polymerase Chain Reaction
RNA Interference
Serine Endopeptidases
Sirtuins

authors with profiles

RONALD A DEPINHO