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2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.
Differing clinical impact of BRCA1 and BRCA2 mutations in serous ovarian cancer.
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Differing clinical impact of BRCA1 and BRCA2 mutations in serous ovarian cancer.
Differing clinical impact of BRCA1 and BRCA2 mutations in serous ovarian cancer. Pharmacogenomics. 2012 Oct; 13(13):1523-35.
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PubMed
subject areas
BRCA1 Protein
BRCA2 Protein
DNA Repair
Female
Genes, BRCA1
Genes, BRCA2
Genetic Predisposition to Disease
Genomic Instability
Humans
Mutation
Ovarian Neoplasms
Prognosis
authors with profiles
ANIL K SOOD