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FoxO transcription factors promote AKT Ser473 phosphorylation and renal tumor growth in response to pharmacologic inhibition of the PI3K-AKT pathway.
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FoxO transcription factors promote AKT Ser473 phosphorylation and renal tumor growth in response to pharmacologic inhibition of the PI3K-AKT pathway.
FoxO transcription factors promote AKT Ser473 phosphorylation and renal tumor growth in response to pharmacologic inhibition of the PI3K-AKT pathway. Cancer Res. 2014 Mar 15; 74(6):1682-93.
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PubMed
subject areas
Animals
Antineoplastic Agents
Carcinoma, Renal Cell
Carrier Proteins
Cell Line, Tumor
Cell Proliferation
Cell Survival
Forkhead Box Protein O1
Forkhead Box Protein O3
Forkhead Transcription Factors
Gene Expression Regulation, Neoplastic
HEK293 Cells
Humans
Imidazoles
Kidney Neoplasms
Mice
Mice, Nude
Phosphatidylinositol 3-Kinases
Phosphorylation
Promoter Regions, Genetic
Protein Binding
Protein Processing, Post-Translational
Proto-Oncogene Proteins c-akt
Quinolines
Rapamycin-Insensitive Companion of mTOR Protein
Tumor Burden
Xenograft Model Antitumor Assays
authors with profiles
DOS SARBASSOV
LI MA
BOYI GAN