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Farnesyltransferase inhibitor R115777 in myelodysplastic syndrome: clinical and biologic activities in the phase 1 setting.
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Farnesyltransferase inhibitor R115777 in myelodysplastic syndrome: clinical and biologic activities in the phase 1 setting.
Farnesyltransferase inhibitor R115777 in myelodysplastic syndrome: clinical and biologic activities in the phase 1 setting. Blood. 2003 Dec 15; 102(13):4527-34.
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PubMed
subject areas
Aged
Alkyl and Aryl Transferases
Carrier Proteins
Dose-Response Relationship, Drug
Enzyme Activation
Enzyme Inhibitors
Farnesyltranstransferase
Female
Genes, ras
Heat-Shock Proteins
HSP40 Heat-Shock Proteins
Humans
Male
Maximum Tolerated Dose
Middle Aged
Myelodysplastic Syndromes
Protein Prenylation
Protein Processing, Post-Translational
Proto-Oncogene Proteins p21(ras)
Quinolones
Remission Induction
Signal Transduction
Treatment Outcome
Tumor Necrosis Factor-alpha
authors with profiles
HAGOP M KANTARJIAN
JORGE E CORTES