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YUKA MORIKAWA

Address6770 BERTNER AVE SUITE C330,C1095
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Morikawa Y, Kim JH, Li RG, Liu L, Liu S, Deshmukh V, Hill MC, Martin JF. YAP Overcomes Mechanical Barriers to Induce Mitotic Rounding and Adult Cardiomyocyte Division. Circulation. 2025 Jan 07; 151(1):76-93. PMID: 39392007; PMCID: PMC11671297.
      Citations:    
    2. Liu S, Deshmukh V, Meng F, Wang Y, Morikawa Y, Steimle JD, Li RG, Wang J, Martin JF. Microtubules Sequester Acetylated YAP in the Cytoplasm and Inhibit Heart Regeneration. Circulation. 2025 Jan 07; 151(1):59-75. PMID: 39185559; PMCID: PMC11671299.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Li RG, Li X, Morikawa Y, Grisanti-Canozo FJ, Meng F, Tsai CR, Zhao Y, Liu L, Kim J, Xie B, Klysik E, Liu S, Samee MAH, Martin JF. YAP induces a neonatal-like pro-renewal niche in the adult heart. Nat Cardiovasc Res. 2024 Mar; 3(3):283-300. PMID: 38510108; PMCID: PMC10954255.
      Citations: 7     
    4. Long H, Steimle JD, Grisanti Canozo FJ, Kim JH, Li X, Morikawa Y, Park M, Turaga D, Adachi I, Wythe JD, Samee MAH, Martin JF, Long H, Steimle JD, Grisanti Canozo FJ, Kim JH, Li X, Morikawa Y, Park M, Turaga D, Adachi I, Wythe JD, Samee MAH, Martin JF. Endothelial cells adopt a pro-reparative immune responsive signature during cardiac injury. Life Sci Alliance. 2024 02; 7(2). PMID: 38012001; PMCID: PMC10681909.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Hill MC, Kadow ZA, Long H, Morikawa Y, Martin TJ, Birks EJ, Campbell KS, Nerbonne J, Lavine K, Wadhwa L, Wang J, Turaga D, Adachi I, Martin JF. Integrated multi-omic characterization of congenital heart disease. Nature. 2022 08; 608(7921):181-191. PMID: 35732239; PMCID: PMC10405779.
      Citations:    Fields:    
    6. Aharonov A, Shakked A, Umansky KB, Savidor A, Genzelinakh A, Kain D, Lendengolts D, Revach OY, Morikawa Y, Dong J, Levin Y, Geiger B, Martin JF, Tzahor E. ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration. Nat Cell Biol. 2020 11; 22(11):1346-1356. PMID: 33046882.
      Citations:    
    7. Arai K, Morikawa Y, Ubukata N, Sugimoto K. Synergistic reduction in albuminuria in type 2 diabetic mice by esaxerenone (CS-3150), a novel nonsteroidal selective mineralocorticoid receptor blocker, combined with an angiotensin II receptor blocker. Hypertens Res. 2020 11; 43(11):1204-1213. PMID: 32616846; PMCID: PMC7685977.
      Citations:    
    8. Monroe TO, Hill MC, Morikawa Y, Leach JP, Heallen T, Cao S, Krijger PHL, de Laat W, Wehrens XHT, Rodney GG, Martin JF. YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In?Vivo. Dev Cell. 2019 03 25; 48(6):765-779.e7. PMID: 30773489; PMCID: PMC6435425.
      Citations: 62     Fields:    Translation:AnimalsCells
    9. Li L, Tao G, Hill MC, Zhang M, Morikawa Y, Martin JF. Pitx2 maintains mitochondrial function during regeneration to prevent myocardial fat deposition. Development. 2018 09 26; 145(18). PMID: 30143541; PMCID: PMC6176932.
      Citations: 18     Fields:    Translation:AnimalsCells
    10. Ito Y, Ohno K, Morikawa Y, Tomizawa A, Mizuno M, Sugidachi A. Vasodilator-stimulated phosphoprotein (VASP) is not a major mediator of platelet aggregation, thrombogenesis, haemostasis, and antiplatelet effect of prasugrel in rats. Sci Rep. 2018 07 02; 8(1):9955. PMID: 29967338; PMCID: PMC6028634.
      Citations:    
    11. Xiao Y, Hill MC, Zhang M, Martin TJ, Morikawa Y, Wang S, Moise AR, Wythe JD, Martin JF. Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development. Dev Cell. 2018 04 23; 45(2):153-169.e6. PMID: 29689192; PMCID: PMC5947860.
      Citations: 63     Fields:    Translation:AnimalsCells
    12. Leach JP, Heallen T, Zhang M, Rahmani M, Morikawa Y, Hill MC, Segura A, Willerson JT, Martin JF. Hippo pathway deficiency reverses systolic heart failure after infarction. Nature. 2017 10 12; 550(7675):260-264. PMID: 28976966; PMCID: PMC5729743.
      Citations: 142     Fields:    Translation:HumansAnimalsCells
    13. Morikawa Y, Heallen T, Leach J, Xiao Y, Martin JF. Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation. Nature. 2017 07 13; 547(7662):227-231. PMID: 28581498; PMCID: PMC5528853.
      Citations:    
    14. Arai K, Morikawa Y, Ubukata N, Tsuruoka H, Homma T. CS-3150, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, Shows Preventive and Therapeutic Effects On Renal Injury in Deoxycorticosterone Acetate/Salt-Induced Hypertensive Rats. J Pharmacol Exp Ther. 2016 09; 358(3):548-57. PMID: 27384074.
      Citations:    
    15. Tao G, Kahr PC, Morikawa Y, Zhang M, Rahmani M, Heallen TR, Li L, Sun Z, Olson EN, Amendt BA, Martin JF. Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury. Nature. 2016 06 02; 534(7605):119-23. PMID: 27251288; PMCID: PMC4999251.
      Citations: 125     Fields:    Translation:AnimalsCells
    16. Arai K, Homma T, Morikawa Y, Ubukata N, Tsuruoka H, Aoki K, Ishikawa H, Mizuno M, Sada T. Pharmacological profile of CS-3150, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist. Eur J Pharmacol. 2015 Aug 15; 761:226-34. PMID: 26073023.
      Citations:    
    17. Morikawa Y, Zhang M, Heallen T, Leach J, Tao G, Xiao Y, Bai Y, Li W, Willerson JT, Martin JF. Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice. Sci Signal. 2015 May 05; 8(375):ra41. PMID: 25943351; PMCID: PMC4442128.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    18. Wurm MF, Hrkac M, Morikawa Y, Schubotz RI. Predicting goals in action episodes attenuates BOLD response in inferior frontal and occipitotemporal cortex. Behav Brain Res. 2014 Nov 01; 274:108-17. PMID: 25108246.
      Citations:    
    19. Wang S, Lopez AL, Morikawa Y, Tao G, Li J, Larina IV, Martin JF, Larin KV. Noncontact quantitative biomechanical characterization of cardiac muscle using shear wave imaging optical coherence tomography. Biomed Opt Express. 2014 Jul 01; 5(7):1980-92. PMID: 25071943; PMCID: PMC4102343.
      Citations: 38     
    20. Heallen T, Morikawa Y, Leach J, Tao G, Willerson JT, Johnson RL, Martin JF. Hippo signaling impedes adult heart regeneration. Development. 2013 Dec; 140(23):4683-90. PMID: 24255096; PMCID: PMC3833428.
      Citations: 192     Fields:    Translation:AnimalsCells
    21. Dirkx E, Gladka MM, Philippen LE, Armand AS, Kinet V, Leptidis S, El Azzouzi H, Salic K, Bourajjaj M, da Silva GJ, Olieslagers S, van der Nagel R, de Weger R, Bitsch N, Kisters N, Seyen S, Morikawa Y, Chanoine C, Heymans S, Volders PG, Thum T, Dimmeler S, Cserjesi P, Eschenhagen T, da Costa Martins PA, De Windt LJ. Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure. Nat Cell Biol. 2013 Nov; 15(11):1282-93. PMID: 24161931.
      Citations:    
    22. Bai Y, Wang J, Morikawa Y, Bonilla-Claudio M, Klysik E, Martin JF. Bmp signaling represses Vegfa to promote outflow tract cushion development. Development. 2013 Aug; 140(16):3395-402. PMID: 23863481; PMCID: PMC3737720.
      Citations: 33     Fields:    Translation:AnimalsCells
    23. Morikawa Y, Leach J, Martin JF. Yin-Yang 1, a new player in early heart development. Circ Res. 2013 Mar 15; 112(6):876-7. PMID: 23493301; PMCID: PMC3955736.
      Citations: 3     Fields:    Translation:AnimalsCells
    24. D'Autr?aux F, Margolis KG, Roberts J, Stevanovic K, Mawe G, Li Z, Karamooz N, Ahuja A, Morikawa Y, Cserjesi P, Setlick W, Gershon MD. Expression level of Hand2 affects specification of enteric neurons and gastrointestinal function in mice. Gastroenterology. 2011 Aug; 141(2):576-87, 587.e1-6. PMID: 21669203; PMCID: PMC3152642.
      Citations:    
    25. Iwata T, Iida S, Hanada S, Inoue H, Morikawa Y, Inoue K, Kobayashi Y, Miura T. Transbronchial occlusion of a malignant bronchopleural fistula with cyanoacrylate glue. J Bronchology Interv Pulmonol. 2011 Apr; 18(2):176-8. PMID: 23169091.
      Citations:    
    26. Barnes RM, Firulli BA, VanDusen NJ, Morikawa Y, Conway SJ, Cserjesi P, Vincentz JW, Firulli AB. Hand2 loss-of-function in Hand1-expressing cells reveals distinct roles in epicardial and coronary vessel development. Circ Res. 2011 Apr 15; 108(8):940-9. PMID: 21350214; PMCID: PMC3086599.
      Citations:    
    27. Maska EL, Cserjesi P, Hua LL, Garstka ME, Brody HM, Morikawa Y. A Tlx2-Cre mouse line uncovers essential roles for hand1 in extraembryonic and lateral mesoderm. Genesis. 2010 Aug; 48(8):479-84. PMID: 20506548; PMCID: PMC2955361.
      Citations:    
    28. Zehir A, Hua LL, Maska EL, Morikawa Y, Cserjesi P. Dicer is required for survival of differentiating neural crest cells. Dev Biol. 2010 Apr 15; 340(2):459-67. PMID: 20144605; PMCID: PMC2878775.
      Citations:    
    29. Morikawa Y, Zehir A, Maska E, Deng C, Schneider MD, Mishina Y, Cserjesi P. BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways. Development. 2009 Nov; 136(21):3575-84. PMID: 19793887; PMCID: PMC2761108.
      Citations: 43     Fields:    Translation:Cells
    30. Morikawa Y, Maska E, Brody H, Cserjesi P. Sonic hedgehog signaling is required for sympathetic nervous system development. Neuroreport. 2009 May 06; 20(7):684-8. PMID: 19349918.
      Citations:    
    31. Xiong W, He F, Morikawa Y, Yu X, Zhang Z, Lan Y, Jiang R, Cserjesi P, Chen Y. Hand2 is required in the epithelium for palatogenesis in mice. Dev Biol. 2009 Jun 01; 330(1):131-41. PMID: 19341725; PMCID: PMC2745957.
      Citations:    
    32. Morikawa Y, Cserjesi P. Cardiac neural crest expression of Hand2 regulates outflow and second heart field development. Circ Res. 2008 Dec 05; 103(12):1422-9. PMID: 19008477.
      Citations:    
    33. D'Autr?aux F, Morikawa Y, Cserjesi P, Gershon MD. Hand2 is necessary for terminal differentiation of enteric neurons from crest-derived precursors but not for their migration into the gut or for formation of glia. Development. 2007 Jun; 134(12):2237-49. PMID: 17507395.
      Citations:    
    34. Morikawa Y, D'Autr?aux F, Gershon MD, Cserjesi P. Hand2 determines the noradrenergic phenotype in the mouse sympathetic nervous system. Dev Biol. 2007 Jul 01; 307(1):114-26. PMID: 17531968; PMCID: PMC1952239.
      Citations:    
    35. Morikawa Y, Dai YS, Hao J, Bonin C, Hwang S, Cserjesi P. The basic helix-loop-helix factor Hand 2 regulates autonomic nervous system development. Dev Dyn. 2005 Nov; 234(3):613-21. PMID: 16145670; PMCID: PMC2653092.
      Citations:    
    36. Dai YS, Hao J, Bonin C, Morikawa Y, Cserjesi P. JAB1 enhances HAND2 transcriptional activity by regulating HAND2 DNA binding. J Neurosci Res. 2004 Jun 01; 76(5):613-22. PMID: 15139020.
      Citations:    
    37. Morikawa Y, Cserjesi P. Extra-embryonic vasculature development is regulated by the transcription factor HAND1. Development. 2004 May; 131(9):2195-204. PMID: 15073150.
      Citations:    
    38. Terasaka N, Hiroshima A, Koieyama T, Ubukata N, Morikawa Y, Nakai D, Inaba T. T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice. FEBS Lett. 2003 Feb 11; 536(1-3):6-11. PMID: 12586329.
      Citations: 87     Fields:    Translation:Animals
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