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Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS.
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Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS.
Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS. Neuron. 2014 Sep 03; 83(5):1043-50.
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PubMed
subject areas
Adult
Aged
Amyotrophic Lateral Sclerosis
Animals
Biomarkers
C9orf72 Protein
Cell Differentiation
Cells, Cultured
DNA Repeat Expansion
Female
Fibroblasts
G-Quadruplexes
Humans
Male
Middle Aged
Nerve Tissue Proteins
Neurons
Protein Binding
Proteins
RNA, Small Interfering