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Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin.
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Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin.
Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. Nat Commun. 2021 09 06; 12(1):5296.
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PubMed
subject areas
Animals
Endothelial Cells
Endothelium, Vascular
Forkhead Box Protein O1
Gene Expression Regulation
Genes, Reporter
Glucose
Glucose Tolerance Test
Green Fluorescent Proteins
HEK293 Cells
Humans
Hyperglycemia
Insulin
Insulin Receptor Substrate Proteins
Insulin-Secreting Cells
Low Density Lipoprotein Receptor-Related Protein-1
Male
Mice
Mice, Knockout
Osteoblasts
Osteocalcin
Proto-Oncogene Proteins c-akt
Receptor, IGF Type 1
Receptors, G-Protein-Coupled
Signal Transduction
authors with profiles
PRADIP SAHA
JIZHONG CHENG
CRISTIAN COARFA
CHRISTIE BALLANTYNE
XINCHUN PI
HUA MAO
ZHENG SUN