"Prolyl Hydroxylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that specifically hydroxylate PROLINE residues on proteins.
Descriptor ID |
D064828
|
MeSH Number(s) |
D08.811.682.690.416.617 D08.811.682.690.708.694
|
Concept/Terms |
Prolyl Hydroxylases- Prolyl Hydroxylases
- Hydroxylases, Prolyl
- Prolyl Hydroxylase
- Proline,2-Oxoglutarate 4-Dioxygenase
- Prolyl 4-Hydroxylase
- Peptidyl Prolyl Hydroxylase
- Proline Hydroxylase
|
Below are MeSH descriptors whose meaning is more general than "Prolyl Hydroxylases".
Below are MeSH descriptors whose meaning is more specific than "Prolyl Hydroxylases".
This graph shows the total number of publications written about "Prolyl Hydroxylases" by people in this website by year, and whether "Prolyl Hydroxylases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2019 | 1 | 0 | 1 |
2021 | 1 | 1 | 2 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Prolyl Hydroxylases" by people in Profiles.
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Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2023 10; 104(4):655-680.
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P4HA2-induced prolyl hydroxylation suppresses YAP1-mediated prostate cancer cell migration, invasion, and metastasis. Oncogene. 2021 10; 40(41):6049-6056.
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Airway stem cells sense hypoxia and differentiate into protective solitary neuroendocrine cells. Science. 2021 01 01; 371(6524):52-57.
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Biallelic loss-of-function P4HTM gene variants cause hypotonia, hypoventilation, intellectual disability, dysautonomia, epilepsy, and eye abnormalities (HIDEA syndrome). Genet Med. 2019 10; 21(10):2355-2363.
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Reducing radiation-induced gastrointestinal toxicity - the role of the PHD/HIF axis. J Clin Invest. 2016 10 03; 126(10):3708-3715.
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Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin. Genes Dev. 2015 Apr 15; 29(8):817-31.
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HIF targets in bone remodeling and metastatic disease. Pharmacol Ther. 2015 Jun; 150:169-77.