"Cdh1 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cdh1 is an activator of the anaphase-promoting complex-cyclosome, and is involved in substrate recognition. It associates with the complex in late MITOSIS from anaphase through G1 to regulate activity of CYCLIN-DEPENDENT KINASES and to prevent premature DNA replication.
| Descriptor ID |
D064200
|
| MeSH Number(s) |
D08.811.464.938.750.092.999 D12.776.167.024.999
|
| Concept/Terms |
Cdh1 Proteins- Cdh1 Proteins
- Fzr1 Protein
- Cdh1 Subunit, Anaphase-Promoting Complex
- Cdh1 Subunit, Anaphase Promoting Complex
- APC-C Activator Protein CDH1
- Fizzy Cell Division Cycle 20 Related 1
|
Below are MeSH descriptors whose meaning is more general than "Cdh1 Proteins".
Below are MeSH descriptors whose meaning is more specific than "Cdh1 Proteins".
This graph shows the total number of publications written about "Cdh1 Proteins" by people in this website by year, and whether "Cdh1 Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cdh1 Proteins" by people in Profiles.
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De novo FZR1 loss-of-function variants cause developmental and epileptic encephalopathies. Brain. 2022 06 03; 145(5):1684-1697.
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FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia. Blood. 2017 04 06; 129(14):1958-1968.
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Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair. Mol Cell Biol. 2015 Nov; 35(21):3657-68.
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Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment. Oncogene. 2015 May 07; 34(19):2471-82.
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miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion. PLoS Genet. 2014 Feb; 10(2):e1004177.
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Loss of CDH1 and Pten accelerates cellular invasiveness and angiogenesis in the mouse uterus. Biol Reprod. 2013 Jul; 89(1):8.
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Novel mutations target distinct subgroups of medulloblastoma. Nature. 2012 Aug 02; 488(7409):43-8.
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CDH1 is essential for endometrial differentiation, gland development, and adult function in the mouse uterus. Biol Reprod. 2012 May; 86(5):141, 1-10.
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The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory. Nat Cell Biol. 2008 Sep; 10(9):1083-9.
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Functional analysis of APC-Cdh1. Methods Mol Biol. 2004; 281:189-98.