"Cdc20 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly conserved proteins that specifically bind to and activate the anaphase-promoting complex-cyclosome, promoting ubiquitination and proteolysis of cell-cycle-regulatory proteins. Cdc20 is essential for anaphase-promoting complex activity, initiation of anaphase, and cyclin proteolysis during mitosis.
| Descriptor ID |
D064199
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| MeSH Number(s) |
D08.811.464.938.750.092.998 D12.776.167.024.998
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cdc20 Proteins".
Below are MeSH descriptors whose meaning is more specific than "Cdc20 Proteins".
This graph shows the total number of publications written about "Cdc20 Proteins" by people in this website by year, and whether "Cdc20 Proteins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cdc20 Proteins" by people in Profiles.
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Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2. Genes Dev. 2016 05 15; 30(10):1187-97.
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APC(Cdc20) suppresses apoptosis through targeting Bim for ubiquitination and destruction. Dev Cell. 2014 May 27; 29(4):377-91.
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Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression. J Hematol Oncol. 2012 Apr 04; 5:15.
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Inhibition of gliomagenesis and attenuation of mitotic transition by MIIP. Oncogene. 2010 Jun 17; 29(24):3501-8.
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Aurora A regulates prometaphase progression by inhibiting the ability of RASSF1A to suppress APC-Cdc20 activity. Cancer Res. 2009 Mar 15; 69(6):2314-23.
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The centrosomal protein RAS association domain family protein 1A (RASSF1A)-binding protein 1 regulates mitotic progression by recruiting RASSF1A to spindle poles. J Biol Chem. 2005 Feb 04; 280(5):3920-7.
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Control of APC-Cdc20 by the tumor suppressor RASSF1A. Cell Cycle. 2004 May; 3(5):574-6.
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The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex. Nat Cell Biol. 2004 Feb; 6(2):129-37.
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Transcriptional upregulation and activation of p55Cdc via p34(cdc2) in Taxol-induced apoptosis. Oncogene. 2001 May 03; 20(20):2537-43.