Apc2 Subunit, Anaphase-Promoting Complex-Cyclosome
"Apc2 Subunit, Anaphase-Promoting Complex-Cyclosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Together with the Apc11 subunit, forms the catalytic core of the E3 ubiquitin ligase anaphase-promoting complex (APC-C). Its N-terminus has cullin domains which associate with the RING FINGER DOMAINS of Apc11. Apc2 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions.
Descriptor ID |
D064190
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MeSH Number(s) |
D08.811.464.938.750.092.750 D12.776.167.024.750
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Concept/Terms |
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