"X-Box Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic leucine zipper transcription factor that regulates expression of MHC CLASS II GENES through its binding to a conserved X-box DNA sequence in the promoter region. It regulates the expression of genes involved in the UNFOLDED PROTEIN RESPONSE.
| Descriptor ID |
D000071717
|
| MeSH Number(s) |
D12.776.260.108.937 D12.776.930.127.937
|
| Concept/Terms |
X-Box Binding Protein 1- X-Box Binding Protein 1
- X Box Binding Protein 1
- TREB5 Protein
- Tax-Responsive Element-Binding Protein 5
- Tax Responsive Element Binding Protein 5
- XBP-1 Protein
- XBP 1 Protein
- TREB-5 Protein
- TREB 5 Protein
- XBP2 Protein
|
Below are MeSH descriptors whose meaning is more general than "X-Box Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "X-Box Binding Protein 1".
This graph shows the total number of publications written about "X-Box Binding Protein 1" by people in this website by year, and whether "X-Box Binding Protein 1" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 1 | 3 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 2 | 0 | 2 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "X-Box Binding Protein 1" by people in Profiles.
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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018 04 02; 128(4):1283-1299.
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Hepatocyte nuclear factor 4a is required for cell differentiation and homeostasis in the adult mouse gastric epithelium. Am J Physiol Gastrointest Liver Physiol. 2016 08 01; 311(2):G267-75.
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Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4a (HNF4?) Is Vital to Beta-cell Function. J Biol Chem. 2016 Mar 18; 291(12):6146-57.
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Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metab. 2014 Sep 02; 20(3):471-82.
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XBP1 promotes triple-negative breast cancer by controlling the HIF1a pathway. Nature. 2014 Apr 03; 508(7494):103-107.
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Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress. J Biol Chem. 2012 Jun 01; 287(23):19687-98.
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Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells. Physiol Genomics. 2011 Feb 11; 43(3):174-86.
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XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum. Gastroenterology. 2010 Dec; 139(6):2038-49.
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Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid leukaemia. J Cell Mol Med. 2010 Jun; 14(6B):1509-19.