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MICHAEL ITTMANN

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Urology
    DivisionUrology


    Collapse Research 
    Collapse research activities and funding
    I01BX002560     (ITTMANN, MICHAEL M)Oct 1, 2014 - Mar 31, 2023
    NIH
    A novel oncogenic axis in African American prostate cancer
    Role: Principal Investigator
    P20DK097775     (ITTMANN, MICHAEL M)Sep 29, 2012 - Jul 31, 2015
    NIH
    Mechanisms of Cytokine Induced Lower Urinary Track Pathology
    Role: Principal Investigator
    U01CA141497     (ITTMANN, MICHAEL M)Sep 9, 2009 - Aug 31, 2015
    NIH
    Role of FGFR1 signaling in distinct cell lineages in prostate cancer progresssion
    Role: Principal Investigator
    R01DK083244     (ITTMANN, MICHAEL M)Mar 24, 2009 - Feb 28, 2014
    NIH
    Cellular Senescence in the Pathogenesis of Benign Prostatic Hyperplasia
    Role: Principal Investigator
    R01AG021383     (ITTMANN, MICHAEL M.)Jul 1, 2002 - Jun 30, 2007
    NIH
    Cytokines and FGFs in prostate cancer progression
    Role: Principal Investigator
    R01DK054170     (ITTMANN, MICHAEL M.)Sep 30, 1997 - Aug 31, 2005
    NIH
    ROLE OF FIBROBLAST GROWTH FACTORS IN PROSTATE GROWTH
    Role: Principal Investigator
    P50CA058204     (ITTMANN, MICHAEL M.)Sep 30, 1992 - May 31, 2010
    NIH
    SPORE in Prostate Cancer
    Role: Principal Investigator
    R29GM040560     (ITTMANN, MICHAEL M.)Jul 1, 1988 - Jun 30, 1994
    NIH
    CLONING &CHARACTERIZATION OF CELL PROLIFERATION GENES
    Role: Principal Investigator
    F32GM011401     (ITTMANN, MICHAEL M.)Nov 29, 1986
    NIH
    CLONING AND CHARACTERIZATION OF CELL CYCLE GENES
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Kriseman ML, Tang S, Liao Z, Jiang P, Parks SE, Cope DI, Yuan F, Chen F, Masand RP, Castro PD, Ittmann MM, Creighton CJ, Tan Z, Monsivais D. SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration. Commun Biol. 2023 03 11; 6(1):261. PMID: 36906706; PMCID: PMC10008566.
      Citations:    Translation:Animals
    2. Villanueva H, Wells GA, Miller MT, Villanueva M, Pathak R, Castro P, Ittmann MM, Sikora AG, Lerner SP. Characterizing treatment resistance in muscle invasive bladder cancer using the chicken egg chorioallantoic membrane patient-derived xenograft model. Heliyon. 2022 Dec; 8(12):e12570. PMID: 36643309; PMCID: PMC9834740.
      Citations:    
    3. Kumar V, Randhawa P, Bilodeau R, Mercola D, McClelland M, Agrawal A, Nguyen J, Castro P, Ittmann MM, Rahmatpanah F. Spatial Profiling of the Prostate Cancer Tumor Microenvironment Reveals Multiple Differences in Gene Expression and Correlation with Recurrence Risk. Cancers (Basel). 2022 Oct 08; 14(19). PMID: 36230846; PMCID: PMC9562240.
      Citations:    
    4. Szwarc MM, Hai L, Maurya VK, Rajapakshe K, Perera D, Ittmann MM, Mo Q, Lin Y, Bettini ML, Coarfa C, Lydon JP. Histopathologic and transcriptomic phenotypes of a conditional RANKL transgenic mouse thymus. Cytokine. 2022 12; 160:156022. PMID: 36099756.
      Citations:    
    5. Berchuck JE, Adib E, Abou Alaiwi S, Dash AK, Shin JN, Lowder D, McColl C, Castro P, Carelli R, Benedetti E, Deng J, Robertson M, Baca SC, Bell C, McClure HM, El Zarif T, Davidsohn MP, Lakshminarayanan G, Rizwan K, Skapura DG, Grimm SL, Davis CM, Ehli EA, Kelleher KM, Seo JH, Mitsiades N, Coarfa C, Pomerantz MM, Loda M, Ittmann M, Freedman ML, Kaochar S, Berchuck JE, Adib E, Abou Alaiwi S, Dash AK, Shin JN, Lowder D, McColl C, Castro P, Carelli R, Benedetti E, Deng J, Robertson M, Baca SC, Bell C, McClure HM, El Zarif T, Davidsohn MP, Lakshminarayanan G, Rizwan K, Skapura DG, Grimm SL, Davis CM, Ehli EA, Kelleher KM, Seo JH, Mitsiades N, Coarfa C, Pomerantz MM, Loda M, Ittmann M, Freedman ML, Kaochar S. The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response. Cancer Res. 2022 08 16; 82(16):2848-2859. PMID: 35731919; PMCID: PMC9379363.
      Citations:    Fields:    
    6. Pulliam TL, Awad D, Han JJ, Murray MM, Ackroyd JJ, Goli P, Oakhill JS, Scott JW, Ittmann MM, Frigo DE, Pulliam TL, Awad D, Han JJ, Murray MM, Ackroyd JJ, Goli P, Oakhill JS, Scott JW, Ittmann MM, Frigo DE. Systemic Ablation of Camkk2 Impairs Metastatic Colonization and Improves Insulin Sensitivity in TRAMP Mice: Evidence for Cancer Cell-Extrinsic CAMKK2 Functions in Prostate Cancer. Cells. 2022 06 10; 11(12). PMID: 35741020; PMCID: PMC9221545.
      Citations:    Fields:    Translation:HumansAnimals
    7. Krieger KL, Gohlke JH, Lee KJ, Piyarathna DWB, Castro PD, Jones JA, Ittmann MM, Gassman NR, Sreekumar A, Krieger KL, Gohlke JH, Lee KJ, Piyarathna DWB, Castro PD, Jones JA, Ittmann MM, Gassman NR, Sreekumar A. Repair-Assisted Damage Detection Reveals Biological Disparities in Prostate Cancer between African Americans and European Americans. Cancers (Basel). 2022 Feb 17; 14(4). PMID: 35205762; PMCID: PMC8870190.
      Citations:    
    8. Ruder S, Gao Y, Ding Y, Bu P, Miles B, De Marzo A, Wheeler T, McKenney JK, Auman H, Fazli L, Simko J, Hurtado-Coll A, Troyer DA, Carroll PR, Gleave M, Platz E, Trock B, Han M, Sayeeduddin M, True LD, Rowley D, Lin DW, Nelson PS, Thompson IM, Feng Z, Wei W, Brooks JD, Ittmann M, Lee M, Ayala G, Ruder S, Gao Y, Ding Y, Bu P, Miles B, De Marzo A, Wheeler T, McKenney JK, Auman H, Fazli L, Simko J, Hurtado-Coll A, Troyer DA, Carroll PR, Gleave M, Platz E, Trock B, Han M, Sayeeduddin M, True LD, Rowley D, Lin DW, Nelson PS, Thompson IM, Feng Z, Wei W, Brooks JD, Ittmann M, Lee M, Ayala G. Development and validation of a quantitative reactive stroma biomarker (qRS) for prostate cancer prognosis. Hum Pathol. 2022 04; 122:84-91. PMID: 35176252; PMCID: PMC9832989.
      Citations:    Fields:    Translation:Humans
    9. Lowder D, Rizwan K, McColl C, Paparella A, Ittmann M, Mitsiades N, Kaochar S, Lowder D, Rizwan K, McColl C, Paparella A, Ittmann M, Mitsiades N, Kaochar S. Racial disparities in prostate cancer: A complex interplay between socioeconomic inequities and genomics. Cancer Lett. 2022 04 10; 531:71-82. PMID: 35122875; PMCID: PMC9701576.
      Citations:    Fields:    Translation:Humans
    10. Ravindran A, Piyarathna DWB, Gohlke J, Putluri V, Soni T, Lloyd S, Castro P, Pennathur S, Jones JA, Ittmann M, Putluri N, Michailidis G, Rajendiran TM, Sreekumar A, Ravindran A, Piyarathna DWB, Gohlke J, Putluri V, Soni T, Lloyd S, Castro P, Pennathur S, Jones JA, Ittmann M, Putluri N, Michailidis G, Rajendiran TM, Sreekumar A. Lipid Alterations in African American Men with Prostate Cancer. Metabolites. 2021 Dec 22; 12(1). PMID: 35050130; PMCID: PMC8779756.
      Citations: 1     
    11. Kumar V, McClelland M, Nguyen J, De Robles G, Ittmann M, Castro P, Mercola D, Jia Z, Rahmatpanah F, Kumar V, McClelland M, Nguyen J, De Robles G, Ittmann M, Castro P, Mercola D, Jia Z, Rahmatpanah F. Expression of Endogenous Retroviral RNA in Prostate Tumors has Prognostic Value and Shows Differences among Americans of African Versus European/Middle Eastern Ancestry. Cancers (Basel). 2021 Dec 17; 13(24). PMID: 34944967; PMCID: PMC8699453.
      Citations:    
    12. Aytatli A, Barlak N, Sanli F, Caglar HO, Gundogdu B, Tatar A, Ittmann M, Karatas OF, Aytatli A, Barlak N, Sanli F, Caglar HO, Gundogdu B, Tatar A, Ittmann M, Karatas OF. AZD4547 targets the FGFR/Akt/SOX2 axis to overcome paclitaxel resistance in head and neck cancer. Cell Oncol (Dordr). 2022 Feb; 45(1):41-56. PMID: 34837170.
      Citations:    Fields:    Translation:HumansCells
    13. Wang Z, Hulsurkar M, Zhuo L, Xu J, Yang H, Naderinezhad S, Wang L, Zhang G, Ai N, Li L, Chang JT, Zhang S, Fazli L, Creighton CJ, Bai F, Ittmann MM, Gleave ME, Li W, Wang Z, Hulsurkar M, Zhuo L, Xu J, Yang H, Naderinezhad S, Wang L, Zhang G, Ai N, Li L, Chang JT, Zhang S, Fazli L, Creighton CJ, Bai F, Ittmann MM, Gleave ME, Li W. CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation. Neoplasia. 2021 11; 23(11):1147-1165. PMID: 34706306; PMCID: PMC8551525.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    14. Shao L, Wang J, Karatas O, Ittmann M, Shao L, Wang J, Karatas O, Ittmann M. MEX3D is an oncogenic driver in prostate cancer. Prostate. 2021 11; 81(15):1202-1213. PMID: 34455614; PMCID: PMC8460603.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    15. Ho SR, Lee YC, Ittmann MM, Lin FT, Chan KS, Lin WC, Ho SR, Lee YC, Ittmann MM, Lin FT, Chan KS, Lin WC. RNF144A deficiency promotes PD-L1 protein stabilization and carcinogen-induced bladder tumorigenesis. Cancer Lett. 2021 11 01; 520:344-360. PMID: 34400221; PMCID: PMC9420248.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    16. Zhang M, Ceyhan Y, Kaftanovskaya EM, Vasquez JL, Vacher J, Knop FK, Nathanson L, Agoulnik AI, Ittmann MM, Agoulnik IU, Zhang M, Ceyhan Y, Kaftanovskaya EM, Vasquez JL, Vacher J, Knop FK, Nathanson L, Agoulnik AI, Ittmann MM, Agoulnik IU, Vacher J. INPP4B protects from metabolic?syndrome and associated disorders. Commun Biol. 2021 03 26; 4(1):416. PMID: 33772116; PMCID: PMC7998001.
      Citations: 2     Translation:AnimalsCells
    17. Capik O, Sanli F, Kurt A, Ceylan O, Suer I, Kaya M, Ittmann M, Karatas OF, Capik O, Sanli F, Kurt A, Ceylan O, Suer I, Kaya M, Ittmann M, Karatas OF. CASC11 promotes aggressiveness of prostate cancer cells through miR-145/IGF1R axis. Prostate Cancer Prostatic Dis. 2021 09; 24(3):891-902. PMID: 33753875.
      Citations:    Fields:    Translation:HumansCells
    18. Shen T, Wang W, Zhou W, Coleman I, Cai Q, Dong B, Ittmann MM, Creighton CJ, Bian Y, Meng Y, Rowley DR, Nelson PS, Moore DD, Yang F, Shen T, Wang W, Zhou W, Coleman I, Cai Q, Dong B, Ittmann MM, Creighton CJ, Bian Y, Meng Y, Rowley DR, Nelson PS, Moore DD, Yang F. MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT. J Clin Invest. 2021 02 15; 131(4). PMID: 33586682; PMCID: PMC7880415.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    19. Lin C, Blessing AM, Pulliam TL, Shi Y, Wilkenfeld SR, Han JJ, Murray MM, Pham AH, Duong K, Brun SN, Shaw RJ, Ittmann MM, Frigo DE, Lin C, Blessing AM, Pulliam TL, Shi Y, Wilkenfeld SR, Han JJ, Murray MM, Pham AH, Duong K, Brun SN, Shaw RJ, Ittmann MM, Frigo DE. Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling. Oncogene. 2021 03; 40(9):1690-1705. PMID: 33531625; PMCID: PMC7935762.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    20. Pons-Faudoa FP, Sizovs A, Shelton KA, Momin Z, Niles JA, Bushman LR, Xu J, Chua CYX, Nichols JE, Demaria S, Ittmann MM, Hawkins T, Rooney JF, Marzinke MA, Kimata JT, Anderson PL, Nehete PN, Arduino RC, Ferrari M, Sastry KJ, Grattoni A, Pons-Faudoa FP, Sizovs A, Shelton KA, Momin Z, Niles JA, Bushman LR, Xu J, Chua CYX, Nichols JE, Demaria S, Ittmann MM, Hawkins T, Rooney JF, Marzinke MA, Kimata JT, Anderson PL, Nehete PN, Arduino RC, Ferrari M, Sastry KJ, Grattoni A. Preventive efficacy of a tenofovir alafenamide fumarate nanofluidic implant in SHIV-challenged nonhuman primates. Adv Ther (Weinh). 2021 Mar; 4(3). PMID: 33997267; PMCID: PMC8114879.
      Citations: 9     
    21. Boyukozer FB, Tanoglu EG, Ozen M, Ittmann M, Aslan ES, Boyukozer FB, Tanoglu EG, Ozen M, Ittmann M, Aslan ES. Kallikrein gene family as biomarkers for recurrent prostate cancer. Croat Med J. 2020 Oct 31; 61(5):450-456. PMID: 33150763; PMCID: PMC7684543.
      Citations: 2     Fields:    Translation:Humans
    22. Alhamar M, Tudor Vladislav I, Smith SC, Gao Y, Cheng L, Favazza LA, Alani AM, Ittmann MM, Riddle ND, Whiteley LJ, Gupta NS, Carskadon S, Gomez-Gelvez JC, Chitale DA, Palanisamy N, Hes O, Trpkov K, Williamson SR, Alhamar M, Tudor Vladislav I, Smith SC, Gao Y, Cheng L, Favazza LA, Alani AM, Ittmann MM, Riddle ND, Whiteley LJ, Gupta NS, Carskadon S, Gomez-Gelvez JC, Chitale DA, Palanisamy N, Hes O, Trpkov K, Williamson SR. Gene fusion characterisation of rare aggressive prostate cancer variants-adenosquamous carcinoma, pleomorphic giant-cell carcinoma, and sarcomatoid carcinoma: an analysis of 19 cases. Histopathology. 2020 Dec; 77(6):890-899. PMID: 32639612.
      Citations: 1     Fields:    Translation:Humans
    23. Zhao D, Cai L, Lu X, Liang X, Li J, Chen P, Ittmann M, Shang X, Jiang S, Li H, Meng C, Flores I, Song JH, Horner JW, Lan Z, Wu CJ, Li J, Chang Q, Chen KC, Wang G, Deng P, Spring DJ, Wang YA, DePinho RA, Zhao D, Cai L, Lu X, Liang X, Li J, Chen P, Ittmann M, Shang X, Jiang S, Li H, Meng C, Flores I, Song JH, Horner JW, Lan Z, Wu CJ, Li J, Chang Q, Chen KC, Wang G, Deng P, Spring DJ, Wang YA, DePinho RA. Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer. Cancer Discov. 2020 09; 10(9):1374-1387. PMID: 32385075; PMCID: PMC7483306.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    24. Kemnade JO, Elhalawani H, Castro P, Yu J, Lai S, Ittmann M, Mohamed ASR, Lai SY, Fuller CD, Sikora AG, Sandulache VC, Kemnade JO, Elhalawani H, Castro P, Yu J, Lai S, Ittmann M, Mohamed ASR, Lai SY, Fuller CD, Sikora AG, Sandulache VC. CD8 infiltration is associated with disease control and tobacco exposure in intermediate-risk oropharyngeal cancer. Sci Rep. 2020 01 14; 10(1):243. PMID: 31937831; PMCID: PMC6959290.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    25. Vantaku V, Amara CS, Piyarathna DWB, Donepudi SR, Ambati CR, Putluri V, Tang W, Rajapakshe K, Estecio MR, Terris MK, Castro PD, Ittmann MM, Williams SB, Lerner SP, Sreekumar A, Bollag R, Coarfa C, Kornberg MD, Lotan Y, Ambs S, Putluri N, Vantaku V, Amara CS, Piyarathna DWB, Donepudi SR, Ambati CR, Putluri V, Tang W, Rajapakshe K, Estecio MR, Terris MK, Castro PD, Ittmann MM, Williams SB, Lerner SP, Sreekumar A, Bollag R, Coarfa C, Kornberg MD, Lotan Y, Ambs S, Putluri N. DNA methylation patterns in bladder tumors of African American patients point to distinct alterations in xenobiotic metabolism. Carcinogenesis. 2019 11 25; 40(11):1332-1340. PMID: 31284295; PMCID: PMC6875901.
      Citations: 3     Fields:    Translation:HumansCells
    26. Apprey V, Wang S, Tang W, Kittles RA, Southerland WM, Ittmann M, Kwabi-Addo B, Apprey V, Wang S, Tang W, Kittles RA, Southerland WM, Ittmann M, Kwabi-Addo B. Association of Genetic Ancestry With DNA Methylation Changes in Prostate Cancer Disparity. Anticancer Res. 2019 Nov; 39(11):5861-5866. PMID: 31704810.
      Citations: 3     Fields:    Translation:HumansCells
    27. Sandulache VC, Lei YL, Heasley LE, Chang M, Amos CI, Sturgis EM, Graboyes E, Chiao EY, Rogus-Pulia N, Lewis J, Madabhushi A, Frederick MJ, Sabichi A, Ittmann M, Yarbrough WG, Chung CH, Ferrarotto R, Mai W, Skinner HD, Duvvuri U, Gerngross P, Sikora AG, Sandulache VC, Lei YL, Heasley LE, Chang M, Amos CI, Sturgis EM, Graboyes E, Chiao EY, Rogus-Pulia N, Lewis J, Madabhushi A, Frederick MJ, Sabichi A, Ittmann M, Yarbrough WG, Chung CH, Ferrarotto R, Mai W, Skinner HD, Duvvuri U, Gerngross P, Sikora AG. Innovations in risk-stratification and treatment of Veterans with oropharynx cancer; roadmap of the 2019 Field Based Meeting. Oral Oncol. 2020 03; 102:104440. PMID: 31648864; PMCID: PMC7260859.
      Citations: 1     Fields:    Translation:HumansCells
    28. Shao L, Kahraman N, Yan G, Wang J, Ozpolat B, Ittmann M, Shao L, Kahraman N, Yan G, Wang J, Ozpolat B, Ittmann M. Targeting the TMPRSS2/ERG fusion mRNA using liposomal nanovectors enhances docetaxel treatment in prostate cancer. Prostate. 2020 01; 80(1):65-73. PMID: 31614005; PMCID: PMC6925833.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    29. Barlak N, Capik O, Sanli F, Kilic A, Aytatli A, Yazici A, Ortucu S, Ittmann M, Karatas OF, Barlak N, Capik O, Sanli F, Kilic A, Aytatli A, Yazici A, Ortucu S, Ittmann M, Karatas OF. ING5 inhibits cancer aggressiveness by inhibiting Akt and activating p53 in prostate cancer. Cell Biol Int. 2020 Jan; 44(1):242-252. PMID: 31475765.
      Citations: 3     Fields:    
    30. Hai L, Szwarc MM, Lonard DM, Rajapakshe K, Perera D, Coarfa C, Ittmann M, Fernandez-Valdivia R, Lydon JP, Hai L, Szwarc MM, Lonard DM, Rajapakshe K, Perera D, Coarfa C, Ittmann M, Fernandez-Valdivia R, Lydon JP. Short-term RANKL exposure initiates a neoplastic transcriptional program in the basal epithelium of the murine salivary gland. Cytokine. 2019 11; 123:154745. PMID: 31226438; PMCID: PMC7443928.
      Citations:    Fields:    Translation:AnimalsCells
    31. Wong M, Bierman Y, Pettaway C, Kittles R, Mims M, Jones J, Ittmann M, Wong M, Bierman Y, Pettaway C, Kittles R, Mims M, Jones J, Ittmann M. Comparative analysis of p16 expression among African American and European American prostate cancer patients. Prostate. 2019 08; 79(11):1274-1283. PMID: 31111520; PMCID: PMC6617792.
      Citations: 3     Fields:    Translation:Humans
    32. Liu J, Wang T, Creighton CJ, Wu SP, Ray M, Janardhan KS, Willson CJ, Cho SN, Castro PD, Ittmann MM, Li JL, Davis RJ, DeMayo FJ, Liu J, Wang T, Creighton CJ, Wu SP, Ray M, Janardhan KS, Willson CJ, Cho SN, Castro PD, Ittmann MM, Li JL, Davis RJ, DeMayo FJ. JNK1/2 represses Lkb1-deficiency-induced lung squamous cell carcinoma progression. Nat Commun. 2019 05 14; 10(1):2148. PMID: 31089135; PMCID: PMC6517592.
      Citations: 14     Fields:    Translation:HumansAnimals
    33. Gohlke JH, Lloyd SM, Basu S, Putluri V, Vareed SK, Rasaily U, Piyarathna DWB, Fuentes H, Rajendiran TM, Dorsey TH, Ambati CR, Sonavane R, Karanam B, Bhowmik SK, Kittles R, Ambs S, Mims MP, Ittmann M, Jones JA, Palapattu G, Putluri N, Michailidis G, Sreekumar A, Gohlke JH, Lloyd SM, Basu S, Putluri V, Vareed SK, Rasaily U, Piyarathna DWB, Fuentes H, Rajendiran TM, Dorsey TH, Ambati CR, Sonavane R, Karanam B, Bhowmik SK, Kittles R, Ambs S, Mims MP, Ittmann M, Jones JA, Palapattu G, Putluri N, Michailidis G, Sreekumar A. Methionine-Homocysteine Pathway in African-American Prostate Cancer. JNCI Cancer Spectr. 2019 Jun; 3(2):pkz019. PMID: 31360899; PMCID: PMC6489686.
      Citations: 8     Fields:    
    34. Wei X, Zhang L, Zhou Z, Kwon OJ, Zhang Y, Nguyen H, Dumpit R, True L, Nelson P, Dong B, Xue W, Birchmeier W, Taketo MM, Xu F, Creighton CJ, Ittmann MM, Xin L, Wei X, Zhang L, Zhou Z, Kwon OJ, Zhang Y, Nguyen H, Dumpit R, True L, Nelson P, Dong B, Xue W, Birchmeier W, Taketo MM, Xu F, Creighton CJ, Ittmann MM, Xin L, Birchmeier W. Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms. Cell Stem Cell. 2019 05 02; 24(5):753-768.e6. PMID: 30982770; PMCID: PMC6548441.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    35. Piyarathna DWB, Balasubramanian A, Arnold JM, Lloyd SM, Karanam B, Castro P, Ittmann MM, Putluri N, Navone N, Jones JA, Yu W, Sandulache VC, Sikora AG, Michailidis G, Sreekumar A, Piyarathna DWB, Balasubramanian A, Arnold JM, Lloyd SM, Karanam B, Castro P, Ittmann MM, Putluri N, Navone N, Jones JA, Yu W, Sandulache VC, Sikora AG, Michailidis G, Sreekumar A. ERR1 and PGC1a associated mitochondrial alterations correlate with pan-cancer disparity in African Americans. J Clin Invest. 2019 03 28; 129(6):2351-2356. PMID: 30920960; PMCID: PMC6546480.
      Citations: 11     Fields:    Translation:HumansCells
    36. Miles B, Ittmann M, Wheeler T, Sayeeduddin M, Cubilla A, Rowley D, Bu P, Ding Y, Gao Y, Lee M, Ayala GE, Miles B, Ittmann M, Wheeler T, Sayeeduddin M, Cubilla A, Rowley D, Bu P, Ding Y, Gao Y, Lee M, Ayala GE. Moving Beyond Gleason Scoring. Arch Pathol Lab Med. 2019 05; 143(5):565-570. PMID: 30865488.
      Citations: 3     Fields:    Translation:Humans
    37. Bader DA, Hartig SM, Putluri V, Foley C, Hamilton MP, Smith EA, Saha PK, Panigrahi A, Walker C, Zong L, Martini-Stoica H, Chen R, Rajapakshe K, Coarfa C, Sreekumar A, Mitsiades N, Bankson JA, Ittmann MM, O'Malley BW, Putluri N, McGuire SE, Bader DA, Hartig SM, Putluri V, Foley C, Hamilton MP, Smith EA, Saha PK, Panigrahi A, Walker C, Zong L, Martini-Stoica H, Chen R, Rajapakshe K, Coarfa C, Sreekumar A, Mitsiades N, Bankson JA, Ittmann MM, O'Malley BW, Putluri N, McGuire SE. Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer. Nat Metab. 2019 01; 1(1):70-85. PMID: 31198906; PMCID: PMC6563330.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    38. Suer I, Guzel E, Karatas OF, Creighton CJ, Ittmann M, Ozen M, Suer I, Guzel E, Karatas OF, Creighton CJ, Ittmann M, Ozen M. MicroRNAs as prognostic markers in prostate cancer. Prostate. 2019 02; 79(3):265-271. PMID: 30345533.
      Citations: 12     Fields:    Translation:Humans
    39. Zhang Y, Zheng D, Zhou T, Song H, Hulsurkar M, Su N, Liu Y, Wang Z, Shao L, Ittmann M, Gleave M, Han H, Xu F, Liao W, Wang H, Li W, Zhang Y, Zheng D, Zhou T, Song H, Hulsurkar M, Su N, Liu Y, Wang Z, Shao L, Ittmann M, Gleave M, Han H, Xu F, Liao W, Wang H, Li W. Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers. Nat Commun. 2018 10 04; 9(1):4080. PMID: 30287808; PMCID: PMC6172226.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    40. Singh R, Karri D, Shen H, Shao J, Dasgupta S, Huang S, Edwards DP, Ittmann MM, O'Malley BW, Yi P, Singh R, Karri D, Shen H, Shao J, Dasgupta S, Huang S, Edwards DP, Ittmann MM, O'Malley BW, Yi P. TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis. J Clin Invest. 2018 07 02; 128(7):3129-3143. PMID: 29715200; PMCID: PMC6026011.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    41. Mallick P, Shah P, Ittmann MM, Trivedi M, Hu M, Gao S, Ghose R, Mallick P, Shah P, Ittmann MM, Trivedi M, Hu M, Gao S, Ghose R. Impact of diet on irinotecan toxicity in mice. Chem Biol Interact. 2018 Aug 01; 291:87-94. PMID: 29913120.
      Citations: 4     Fields:    Translation:Animals
    42. Ittmann M, Ittmann M. Anatomy and Histology of the Human and Murine Prostate. Cold Spring Harb Perspect Med. 2018 05 01; 8(5). PMID: 29038334; PMCID: PMC5932577.
      Citations: 15     Fields:    Translation:HumansAnimals
    43. Shao L, Wang J, Karatas OF, Feng S, Zhang Y, Creighton CJ, Ittmann M, Shao L, Wang J, Karatas OF, Feng S, Zhang Y, Creighton CJ, Ittmann M. Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN. Oncotarget. 2018 Mar 06; 9(18):14456-14471. PMID: 29581856; PMCID: PMC5865682.
      Citations: 3     Fields:    
    44. Chen F, Zhang Y, Gibbons DL, Deneen B, Kwiatkowski DJ, Ittmann M, Creighton CJ, Chen F, Zhang Y, Gibbons DL, Deneen B, Kwiatkowski DJ, Ittmann M, Creighton CJ. Pan-Cancer Molecular Classes Transcending Tumor Lineage Across 32 Cancer Types, Multiple Data Platforms, and over 10,000 Cases. Clin Cancer Res. 2018 05 01; 24(9):2182-2193. PMID: 29440175; PMCID: PMC5932236.
      Citations: 34     Fields:    Translation:HumansCells
    45. Coarfa C, Florentin D, Putluri N, Ding Y, Au J, He D, Ragheb A, Frolov A, Michailidis G, Lee M, Kadmon D, Miles B, Smith C, Ittmann M, Rowley D, Sreekumar A, Creighton CJ, Ayala G, Coarfa C, Florentin D, Putluri N, Ding Y, Au J, He D, Ragheb A, Frolov A, Michailidis G, Lee M, Kadmon D, Miles B, Smith C, Ittmann M, Rowley D, Sreekumar A, Creighton CJ, Ayala G. Influence of the neural microenvironment on prostate cancer. Prostate. 2018 Feb; 78(2):128-139. PMID: 29131367; PMCID: PMC5836952.
      Citations: 24     Fields:    Translation:Animals
    46. Bluemn EG, Coleman IM, Lucas JM, Coleman RT, Hernandez-Lopez S, Tharakan R, Bianchi-Frias D, Dumpit RF, Kaipainen A, Corella AN, Yang YC, Nyquist MD, Mostaghel E, Hsieh AC, Zhang X, Corey E, Brown LG, Nguyen HM, Pienta K, Ittmann M, Schweizer M, True LD, Wise D, Rennie PS, Vessella RL, Morrissey C, Nelson PS, Bluemn EG, Coleman IM, Lucas JM, Coleman RT, Hernandez-Lopez S, Tharakan R, Bianchi-Frias D, Dumpit RF, Kaipainen A, Corella AN, Yang YC, Nyquist MD, Mostaghel E, Hsieh AC, Zhang X, Corey E, Brown LG, Nguyen HM, Pienta K, Ittmann M, Schweizer M, True LD, Wise D, Rennie PS, Vessella RL, Morrissey C, Nelson PS. Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling. Cancer Cell. 2017 10 09; 32(4):474-489.e6. PMID: 29017058; PMCID: PMC5750052.
      Citations: 231     Fields:    Translation:HumansAnimalsCells
    47. Chen F, Zhang Y, Bossé D, Lalani AA, Hakimi AA, Hsieh JJ, Choueiri TK, Gibbons DL, Ittmann M, Creighton CJ, Chen F, Zhang Y, Bossé D, Lalani AA, Hakimi AA, Hsieh JJ, Choueiri TK, Gibbons DL, Ittmann M, Creighton CJ, Boss? D. Pan-urologic cancer genomic subtypes that transcend tissue of origin. Nat Commun. 2017 08 04; 8(1):199. PMID: 28775315; PMCID: PMC5543131.
      Citations: 28     Fields:    Translation:HumansCells
    48. Karatas OF, Wang J, Shao L, Ozen M, Zhang Y, Creighton CJ, Ittmann M, Karatas OF, Wang J, Shao L, Ozen M, Zhang Y, Creighton CJ, Ittmann M. miR-33a is a tumor suppressor microRNA that is decreased in prostate cancer. Oncotarget. 2017 Sep 01; 8(36):60243-60256. PMID: 28947967; PMCID: PMC5601135.
      Citations: 16     Fields:    
    49. Wang Y, Wang J, Zhang L, Karatas OF, Shao L, Zhang Y, Castro P, Creighton CJ, Ittmann M, Wang Y, Wang J, Zhang L, Karatas OF, Shao L, Zhang Y, Castro P, Creighton CJ, Ittmann M. RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression. Cancer Res. 2017 08 15; 77(16):4247-4257. PMID: 28611045; PMCID: PMC5559317.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    50. Moss TJ, Qi Y, Xi L, Peng B, Kim TB, Ezzedine NE, Mosqueda ME, Guo CC, Czerniak BA, Ittmann M, Wheeler DA, Lerner SP, Matin SF, Moss TJ, Qi Y, Xi L, Peng B, Kim TB, Ezzedine NE, Mosqueda ME, Guo CC, Czerniak BA, Ittmann M, Wheeler DA, Lerner SP, Matin SF. Comprehensive Genomic Characterization of Upper Tract Urothelial Carcinoma. Eur Urol. 2017 10; 72(4):641-649. PMID: 28601352.
      Citations: 67     Fields:    Translation:Humans
    51. Zhang Y, Kwok-Shing Ng P, Kucherlapati M, Chen F, Liu Y, Tsang YH, de Velasco G, Jeong KJ, Akbani R, Hadjipanayis A, Pantazi A, Bristow CA, Lee E, Mahadeshwar HS, Tang J, Zhang J, Yang L, Seth S, Lee S, Ren X, Song X, Sun H, Seidman J, Luquette LJ, Xi R, Chin L, Protopopov A, Westbrook TF, Shelley CS, Choueiri TK, Ittmann M, Van Waes C, Weinstein JN, Liang H, Henske EP, Godwin AK, Park PJ, Kucherlapati R, Scott KL, Mills GB, Kwiatkowski DJ, Creighton CJ, Zhang Y, Kwok-Shing Ng P, Kucherlapati M, Chen F, Liu Y, Tsang YH, de Velasco G, Jeong KJ, Akbani R, Hadjipanayis A, Pantazi A, Bristow CA, Lee E, Mahadeshwar HS, Tang J, Zhang J, Yang L, Seth S, Lee S, Ren X, Song X, Sun H, Seidman J, Luquette LJ, Xi R, Chin L, Protopopov A, Westbrook TF, Shelley CS, Choueiri TK, Ittmann M, Van Waes C, Weinstein JN, Liang H, Henske EP, Godwin AK, Park PJ, Kucherlapati R, Scott KL, Mills GB, Kwiatkowski DJ, Creighton CJ. A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations. Cancer Cell. 2017 06 12; 31(6):820-832.e3. PMID: 28528867; PMCID: PMC5502825.
      Citations: 189     Fields:    Translation:HumansCells
    52. Ban K, Feng S, Shao L, Ittmann M, Ban K, Feng S, Shao L, Ittmann M. RET Signaling in Prostate Cancer. Clin Cancer Res. 2017 Aug 15; 23(16):4885-4896. PMID: 28490466; PMCID: PMC5609835.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    53. Wang W, Meng Y, Dong B, Dong J, Ittmann MM, Creighton CJ, Lu Y, Zhang H, Shen T, Wang J, Rowley DR, Li Y, Chen F, Moore DD, Yang F, Wang W, Meng Y, Dong B, Dong J, Ittmann MM, Creighton CJ, Lu Y, Zhang H, Shen T, Wang J, Rowley DR, Li Y, Chen F, Moore DD, Yang F. A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis. Neoplasia. 2017 May; 19(5):421-428. PMID: 28433771; PMCID: PMC5402631.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    54. Geng C, Kaochar S, Li M, Rajapakshe K, Fiskus W, Dong J, Foley C, Dong B, Zhang L, Kwon OJ, Shah SS, Bolaki M, Xin L, Ittmann M, O'Malley BW, Coarfa C, Mitsiades N, Geng C, Kaochar S, Li M, Rajapakshe K, Fiskus W, Dong J, Foley C, Dong B, Zhang L, Kwon OJ, Shah SS, Bolaki M, Xin L, Ittmann M, O'Malley BW, Coarfa C, Mitsiades N. SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein. Oncogene. 2017 08 17; 36(33):4767-4777. PMID: 28414305; PMCID: PMC5887163.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    55. Royse KE, Chen L, Berger DH, Ittmann MM, El-Serag HB, Balentine CJ, Graham DY, Richardson PA, Rumbaut RE, Shen X, White DL, Jiao L, Royse KE, Chen L, Berger DH, Ittmann MM, El-Serag HB, Balentine CJ, Graham DY, Richardson PA, Rumbaut RE, Shen X, White DL, Jiao L. Expression of pattern recognition receptor genes and mortality in patients with colorectal adenocarcinoma. Int J Mol Epidemiol Genet. 2017; 8(2):8-18. PMID: 28533893; PMCID: PMC5435667.
      Citations: 4     
    56. Blattner M, Liu D, Robinson BD, Huang D, Poliakov A, Gao D, Nataraj S, Deonarine LD, Augello MA, Sailer V, Ponnala L, Ittmann M, Chinnaiyan AM, Sboner A, Chen Y, Rubin MA, Barbieri CE, Blattner M, Liu D, Robinson BD, Huang D, Poliakov A, Gao D, Nataraj S, Deonarine LD, Augello MA, Sailer V, Ponnala L, Ittmann M, Chinnaiyan AM, Sboner A, Chen Y, Rubin MA, Barbieri CE. SPOP Mutation Drives Prostate Tumorigenesis In?Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling. Cancer Cell. 2017 03 13; 31(3):436-451. PMID: 28292441; PMCID: PMC5384998.
      Citations: 86     Fields:    Translation:HumansAnimalsCells
    57. Hammerich KH, Frolov A, Li R, Ittmann M, Ayala GE, Hammerich KH, Frolov A, Li R, Ittmann M, Ayala GE. Cellular interactions of the phosphorylated form of AKT in prostate cancer. Hum Pathol. 2017 05; 63:98-109. PMID: 28300578.
      Citations: 1     Fields:    Translation:HumansCells
    58. Feng S, Shao L, Castro P, Coleman I, Nelson PS, Smith PD, Davies BR, Ittmann M, Feng S, Shao L, Castro P, Coleman I, Nelson PS, Smith PD, Davies BR, Ittmann M. Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors. Oncotarget. 2017 Jan 24; 8(4):6179-6192. PMID: 28008155; PMCID: PMC5351622.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    59. Brooks M, Mo Q, Krasnow R, Ho PL, Lee YC, Xiao J, Kurtova A, Lerner S, Godoy G, Jian W, Castro P, Chen F, Rowley D, Ittmann M, Chan KS, Brooks M, Mo Q, Krasnow R, Ho PL, Lee YC, Xiao J, Kurtova A, Lerner S, Godoy G, Jian W, Castro P, Chen F, Rowley D, Ittmann M, Chan KS. Positive association of collagen type I with non-muscle invasive bladder cancer progression. Oncotarget. 2016 Dec 13; 7(50):82609-82619. PMID: 27655672; PMCID: PMC5347718.
      Citations: 22     Fields:    Translation:HumansCells
    60. Chaudhury A, Cheema S, Fachini JM, Kongchan N, Lu G, Simon LM, Wang T, Mao S, Rosen DG, Ittmann MM, Hilsenbeck SG, Shaw CA, Neilson JR, Chaudhury A, Cheema S, Fachini JM, Kongchan N, Lu G, Simon LM, Wang T, Mao S, Rosen DG, Ittmann MM, Hilsenbeck SG, Shaw CA, Neilson JR. CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT. Nat Commun. 2016 11 21; 7:13362. PMID: 27869122; PMCID: PMC5121338.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    61. Karatas OF, Suer I, Yuceturk B, Yilmaz M, Oz B, Guven G, Cansiz H, Creighton CJ, Ittmann M, Ozen M, Karatas OF, Suer I, Yuceturk B, Yilmaz M, Oz B, Guven G, Cansiz H, Creighton CJ, Ittmann M, Ozen M. Identification of microRNA profile specific to cancer stem-like cells directly isolated from human larynx cancer specimens. BMC Cancer. 2016 11 05; 16(1):853. PMID: 27816053; PMCID: PMC5097853.
      Citations: 6     Fields:    Translation:HumansCells
    62. Zhang B, Kwon OJ, Henry G, Malewska A, Wei X, Zhang L, Brinkley W, Zhang Y, Castro PD, Titus M, Chen R, Sayeeduddin M, Raj GV, Mauck R, Roehrborn C, Creighton CJ, Strand DW, Ittmann MM, Xin L, Zhang B, Kwon OJ, Henry G, Malewska A, Wei X, Zhang L, Brinkley W, Zhang Y, Castro PD, Titus M, Chen R, Sayeeduddin M, Raj GV, Mauck R, Roehrborn C, Creighton CJ, Strand DW, Ittmann MM, Xin L. Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor. Mol Cell. 2016 09 15; 63(6):976-89. PMID: 27594448; PMCID: PMC5026614.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    63. Zhang L, Wang J, Wang Y, Zhang Y, Castro P, Shao L, Sreekumar A, Putluri N, Guha N, Deepak S, Padmanaban A, Creighton CJ, Ittmann M, Zhang L, Wang J, Wang Y, Zhang Y, Castro P, Shao L, Sreekumar A, Putluri N, Guha N, Deepak S, Padmanaban A, Creighton CJ, Ittmann M. MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer. Cancer Res. 2016 11 01; 76(21):6290-6298. PMID: 27578002; PMCID: PMC5093064.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    64. Xiao L, Feng Q, Zhang Z, Wang F, Lydon JP, Ittmann MM, Xin L, Mitsiades N, He B, Xiao L, Feng Q, Zhang Z, Wang F, Lydon JP, Ittmann MM, Xin L, Mitsiades N, He B. The essential role of GATA transcription factors in adult murine prostate. Oncotarget. 2016 Jul 26; 7(30):47891-47903. PMID: 27374105; PMCID: PMC5216986.
      Citations: 9     Fields:    Translation:HumansAnimals
    65. Sang M, Hulsurkar M, Zhang X, Song H, Zheng D, Zhang Y, Li M, Xu J, Zhang S, Ittmann M, Li W, Sang M, Hulsurkar M, Zhang X, Song H, Zheng D, Zhang Y, Li M, Xu J, Zhang S, Ittmann M, Li W. GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells. Oncotarget. 2016 Jul 19; 7(29):45171-45185. PMID: 27191986; PMCID: PMC5216714.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    66. Farach A, Ding Y, Lee M, Creighton C, Delk NA, Ittmann M, Miles B, Rowley D, Farach-Carson MC, Ayala GE, Farach A, Ding Y, Lee M, Creighton C, Delk NA, Ittmann M, Miles B, Rowley D, Farach-Carson MC, Ayala GE. Neuronal Trans-Differentiation in Prostate Cancer Cells. Prostate. 2016 10; 76(14):1312-25. PMID: 27403603; PMCID: PMC5815867.
      Citations: 10     Fields:    Translation:HumansCells
    67. Su Q, Zhang B, Zhang L, Dang T, Rowley D, Ittmann M, Xin L, Su Q, Zhang B, Zhang L, Dang T, Rowley D, Ittmann M, Xin L. Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer. Oncogene. 2017 02 02; 36(5):618-627. PMID: 27345403; PMCID: PMC5192002.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    68. Wang W, Dong B, Ittmann MM, Yang F, Wang W, Dong B, Ittmann MM, Yang F. A Versatile Gene Delivery System for Efficient and Tumor Specific Gene Manipulation in vivo. Discoveries (Craiova). 2016 Apr-Jun; 4(2). PMID: 27376150; PMCID: PMC4926771.
      Citations: 1     
    69. Zhang Z, Lanz RB, Xiao L, Wang L, Hartig SM, Ittmann MM, Feng Q, He B, Zhang Z, Lanz RB, Xiao L, Wang L, Hartig SM, Ittmann MM, Feng Q, He B. The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors. Oncotarget. 2016 Jun 21; 7(25):37993-38003. PMID: 27191272; PMCID: PMC5122366.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    70. Kwon OJ, Zhang L, Wang J, Su Q, Feng Q, Zhang XH, Mani SA, Paulter R, Creighton CJ, Ittmann MM, Xin L, Kwon OJ, Zhang L, Wang J, Su Q, Feng Q, Zhang XH, Mani SA, Paulter R, Creighton CJ, Ittmann MM, Xin L. Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model. J Clin Invest. 2016 07 01; 126(7):2626-41. PMID: 27294523; PMCID: PMC4922719.
      Citations: 29     Fields:    Translation:AnimalsCells
    71. Xiao L, Lanz RB, Frolov A, Castro PD, Zhang Z, Dong B, Xue W, Jung SY, Lydon JP, Edwards DP, Mancini MA, Feng Q, Ittmann MM, He B, Xiao L, Lanz RB, Frolov A, Castro PD, Zhang Z, Dong B, Xue W, Jung SY, Lydon JP, Edwards DP, Mancini MA, Feng Q, Ittmann MM, He B. The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker. Prostate. 2016 10; 76(14):1271-84. PMID: 27272765.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    72. Kaushik AK, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, Zaslavsky A, Putluri V, Vasu VT, Zhang Y, Khan AS, Lloyd S, Szafran AT, Dasgupta S, Bader DA, Stossi F, Li H, Samanta S, Cao X, Tsouko E, Huang S, Frigo DE, Chan L, Edwards DP, Kaipparettu BA, Mitsiades N, Weigel NL, Mancini M, McGuire SE, Mehra R, Ittmann MM, Chinnaiyan AM, Putluri N, Palapattu GS, Michailidis G, Sreekumar A, Kaushik AK, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, Zaslavsky A, Putluri V, Vasu VT, Zhang Y, Khan AS, Lloyd S, Szafran AT, Dasgupta S, Bader DA, Stossi F, Li H, Samanta S, Cao X, Tsouko E, Huang S, Frigo DE, Chan L, Edwards DP, Kaipparettu BA, Mitsiades N, Weigel NL, Mancini M, McGuire SE, Mehra R, Ittmann MM, Chinnaiyan AM, Putluri N, Palapattu GS, Michailidis G, Sreekumar A. Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nat Commun. 2016 05 19; 7:11612. PMID: 27194471; PMCID: PMC4874037.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    73. Lin SC, Kao CY, Lee HJ, Creighton CJ, Ittmann MM, Tsai SJ, Tsai SY, Tsai MJ, Lin SC, Kao CY, Lee HJ, Creighton CJ, Ittmann MM, Tsai SJ, Tsai SY, Tsai MJ. Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer. Nat Commun. 2016 04 25; 7:11418. PMID: 27108958; PMCID: PMC4848536.
      Citations: 54     Fields:    Translation:HumansAnimals
    74. Lopez SM, Agoulnik AI, Zhang M, Peterson LE, Suarez E, Gandarillas GA, Frolov A, Li R, Rajapakshe K, Coarfa C, Ittmann MM, Weigel NL, Agoulnik IU, Lopez SM, Agoulnik AI, Zhang M, Peterson LE, Suarez E, Gandarillas GA, Frolov A, Li R, Rajapakshe K, Coarfa C, Ittmann MM, Weigel NL, Agoulnik IU. Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression. Clin Cancer Res. 2016 08 01; 22(15):3937-49. PMID: 26968201; PMCID: PMC4970919.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    75. Whittle SB, Reyes S, Du M, Gireud M, Zhang L, Woodfield SE, Ittmann M, Scheurer ME, Bean AJ, Zage PE, Whittle SB, Reyes S, Du M, Gireud M, Zhang L, Woodfield SE, Ittmann M, Scheurer ME, Bean AJ, Zage PE, Whittle SB. A Polymorphism in the FGFR4 Gene Is Associated With Risk of Neuroblastoma and Altered Receptor Degradation. J Pediatr Hematol Oncol. 2016 Mar; 38(2):131-8. PMID: 26840079; PMCID: PMC4758892.
      Citations: 5     Fields:    Translation:Humans
    76. Tsang YH, Dogruluk T, Tedeschi PM, Wardwell-Ozgo J, Lu H, Espitia M, Nair N, Minelli R, Chong Z, Chen F, Chang QE, Dennison JB, Dogruluk A, Li M, Ying H, Bertino JR, Gingras MC, Ittmann M, Kerrigan J, Chen K, Creighton CJ, Eterovic K, Mills GB, Scott KL, Tsang YH, Dogruluk T, Tedeschi PM, Wardwell-Ozgo J, Lu H, Espitia M, Nair N, Minelli R, Chong Z, Chen F, Chang QE, Dennison JB, Dogruluk A, Li M, Ying H, Bertino JR, Gingras MC, Ittmann M, Kerrigan J, Chen K, Creighton CJ, Eterovic K, Mills GB, Scott KL. Functional annotation of rare gene aberration drivers of pancreatic cancer. Nat Commun. 2016 Jan 25; 7:10500. PMID: 26806015; PMCID: PMC4737758.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    77. Paranjape AN, Soundararajan R, Werden SJ, Joseph R, Taube JH, Liu H, Rodriguez-Canales J, Sphyris N, Wistuba I, Miura N, Dhillon J, Mahajan N, Mahajan K, Chang JT, Ittmann M, Maity SN, Logothetis C, Tang DG, Mani SA, Paranjape AN, Soundararajan R, Werden SJ, Joseph R, Taube JH, Liu H, Rodriguez-Canales J, Sphyris N, Wistuba I, Miura N, Dhillon J, Mahajan N, Mahajan K, Chang JT, Ittmann M, Maity SN, Logothetis C, Tang DG, Mani SA. Inhibition of FOXC2 restores epithelial phenotype and drug sensitivity in prostate cancer cells with stem-cell properties. Oncogene. 2016 11 17; 35(46):5963-5976. PMID: 26804168; PMCID: PMC5116559.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    78. Gingras MC, Covington KR, Chang DK, Donehower LA, Gill AJ, Ittmann MM, Creighton CJ, Johns AL, Shinbrot E, Dewal N, Fisher WE, Pilarsky C, Grützmann R, Overman MJ, Jamieson NB, Van Buren G, Drummond J, Walker K, Hampton OA, Xi L, Muzny DM, Doddapaneni H, Lee SL, Bellair M, Hu J, Han Y, Dinh HH, Dahdouli M, Samra JS, Bailey P, Waddell N, Pearson JV, Harliwong I, Wang H, Aust D, Oien KA, Hruban RH, Hodges SE, McElhany A, Saengboonmee C, Duthie FR, Grimmond SM, Biankin AV, Wheeler DA, Gibbs RA, Gingras MC, Covington KR, Chang DK, Donehower LA, Gill AJ, Ittmann MM, Creighton CJ, Johns AL, Shinbrot E, Dewal N, Fisher WE, Australian Pancreatic Cancer Genome Initiative, Pilarsky C, Grützmann R, Overman MJ, Jamieson NB, Van Buren G, Drummond J, Walker K, Hampton OA, Xi L, Muzny DM, Doddapaneni H, Lee SL, Bellair M, Hu J, Han Y, Dinh HH, Dahdouli M, Samra JS, Bailey P, Waddell N, Pearson JV, Harliwong I, Wang H, Aust D, Oien KA, Hruban RH, Hodges SE, McElhany A, Saengboonmee C, Duthie FR, Grimmond SM, Biankin AV, Wheeler DA, Gibbs RA, Gr?tzmann R. Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation. Cell Rep. 2016 Feb 02; 14(4):907-919. PMID: 26804919; PMCID: PMC4982376.
      Citations: 47     Fields:    Translation:HumansCells
    79. Bianchi-Frias D, Basom R, Delrow JJ, Coleman IM, Dakhova O, Qu X, Fang M, Franco OE, Ericson NG, Bielas JH, Hayward SW, True L, Morrissey C, Brown L, Bhowmick NA, Rowley D, Ittmann M, Nelson PS, Bianchi-Frias D, Basom R, Delrow JJ, Coleman IM, Dakhova O, Qu X, Fang M, Franco OE, Ericson NG, Bielas JH, Hayward SW, True L, Morrissey C, Brown L, Bhowmick NA, Rowley D, Ittmann M, Nelson PS. Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations. Mol Cancer Res. 2016 Apr; 14(4):374-84. PMID: 26753621; PMCID: PMC5582956.
      Citations: 21     Fields:    Translation:HumansCells
    80. Woodfield SE, Guo RJ, Liu Y, Major AM, Hollingsworth EF, Indiviglio S, Whittle SB, Mo Q, Bean AJ, Ittmann M, Lopez-Terrada D, Zage PE, Woodfield SE, Guo RJ, Liu Y, Major AM, Hollingsworth EF, Indiviglio S, Whittle SB, Mo Q, Bean AJ, Ittmann M, Lopez-Terrada D, Zage PE. Neuroblastoma patient outcomes, tumor differentiation, and ERK activation are correlated with expression levels of the ubiquitin ligase UBE4B. Genes Cancer. 2016 Jan; 7(1-2):13-26. PMID: 27014418; PMCID: PMC4773702.
      Citations: 5     
    81. Karatas OF, Guzel E, Duz MB, Ittmann M, Ozen M, Karatas OF, Guzel E, Duz MB, Ittmann M, Ozen M. The role of ATP-binding cassette transporter genes in the progression of prostate cancer. Prostate. 2016 Apr; 76(5):434-44. PMID: 26708806.
      Citations: 15     Fields:    Translation:Humans
    82. Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, Rathmell WK, Brooks AN, Hoadley KA, Robertson AG, Brooks D, Bowlby R, Sadeghi S, Shen H, Weisenberger DJ, Bootwalla M, Baylin SB, Laird PW, Cherniack AD, Saksena G, Haake S, Li J, Liang H, Lu Y, Mills GB, Akbani R, Leiserson MD, Raphael BJ, Anur P, Bottaro D, Albiges L, Barnabas N, Choueiri TK, Czerniak B, Godwin AK, Hakimi AA, Ho TH, Hsieh J, Ittmann M, Kim WY, Krishnan B, Merino MJ, Mills Shaw KR, Reuter VE, Reznik E, Shelley CS, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Tickoo S, Burnett K, Crain D, Gardner J, Lau K, Mallery D, Morris S, Paulauskis JD, Penny RJ, Shelton C, Shelton WT, Sherman M, Thompson E, Yena P, Avedon MT, Bowen J, Gastier-Foster JM, Gerken M, Leraas KM, Lichtenberg TM, Ramirez NC, Santos T, Wise L, Zmuda E, Demchok JA, Felau I, Hutter CM, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Zhang J, Ayala B, Baboud J, Chudamani S, Liu J, Lolla L, Naresh R, Pihl T, Sun Q, Wan Y, Wu Y, Ally A, Balasundaram M, Balu S, Beroukhim R, Bodenheimer T, Buhay C, Butterfield YS, Carlsen R, Carter SL, Chao H, Chuah E, Clarke A, Covington KR, Dahdouli M, Dewal N, Dhalla N, Doddapaneni HV, Drummond JA, Gabriel SB, Gibbs RA, Guin R, Hale W, Hawes A, Hayes DN, Holt RA, Hoyle AP, Jefferys SR, Jones SJ, Jones CD, Kalra D, Kovar C, Lewis L, Li J, Ma Y, Marra MA, Mayo M, Meng S, Meyerson M, Mieczkowski PA, Moore RA, Morton D, Mose LE, Mungall AJ, Muzny D, Parker JS, Perou CM, Roach J, Schein JE, Schumacher SE, Shi Y, Simons JV, Sipahimalani P, Skelly T, Soloway MG, Sougnez C, Tam A, Tan D, Thiessen N, Veluvolu U, Wang M, Wilkerson MD, Wong T, Wu J, Xi L, Zhou J, Bedford J, Chen F, Fu Y, Gerstein M, Haussler D, Kasaian K, Lai P, Ling S, Radenbaugh A, Van Den Berg D, Weinstein JN, Zhu J, Albert M, Alexopoulou I, Andersen JJ, Auman JT, Bartlett J, Bastacky S, Bergsten J, Blute ML, Boice L, Bollag RJ, Boyd J, Castle E, Chen YB, Cheville JC, Curley E, Davies B, DeVolk A, Dhir R, Dike L, Eckman J, Engel J, Harr J, Hrebinko R, Huang M, Huelsenbeck-Dill L, Iacocca M, Jacobs B, Lobis M, Maranchie JK, McMeekin S, Myers J, Nelson J, Parfitt J, Parwani A, Petrelli N, Rabeno B, Roy S, Salner AL, Slaton J, Stanton M, Thompson RH, Thorne L, Tucker K, Weinberger PM, Winemiller C, Zach LA, Zuna R, Cancer Genome Atlas Research Network, Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C, Wheeler DA, Murray BA, Schmidt L, Vocke CD, Peto M, Al Mamun AA, Shinbrot E, Sethi A, Brooks S, Rathmell WK, Brooks AN, Hoadley KA, Robertson AG, Brooks D, Bowlby R, Sadeghi S, Shen H, Weisenberger DJ, Bootwalla M, Baylin SB, Laird PW, Cherniack AD, Saksena G, Haake S, Li J, Liang H, Lu Y, Mills GB, Akbani R, Leiserson MD, Raphael BJ, Anur P, Bottaro D, Albiges L, Barnabas N, Choueiri TK, Czerniak B, Godwin AK, Hakimi AA, Ho TH, Hsieh J, Ittmann M, Kim WY, Krishnan B, Merino MJ, Mills Shaw KR, Reuter VE, Reznik E, Shelley CS, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Tickoo S, Burnett K, Crain D, Gardner J, Lau K, Mallery D, Morris S, Paulauskis JD, Penny RJ, Shelton C, Shelton WT, Sherman M, Thompson E, Yena P, Avedon MT, Bowen J, Gastier-Foster JM, Gerken M, Leraas KM, Lichtenberg TM, Ramirez NC, Santos T, Wise L, Zmuda E, Demchok JA, Felau I, et al. Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma. N Engl J Med. 2016 Jan 14; 374(2):135-45. PMID: 26536169; PMCID: PMC4775252.
      Citations: 414     Fields:    Translation:HumansCells
    83. Karatas OF, Suer I, Yuceturk B, Yilmaz M, Hajiyev Y, Creighton CJ, Ittmann M, Ozen M, Karatas OF, Suer I, Yuceturk B, Yilmaz M, Hajiyev Y, Creighton CJ, Ittmann M, Ozen M. The role of miR-145 in stem cell characteristics of human laryngeal squamous cell carcinoma Hep-2 cells. Tumour Biol. 2016 Mar; 37(3):4183-92. PMID: 26490990.
      Citations: 14     Fields:    Translation:HumansCells
    84. Vital P, Castro P, Ittmann M, Vital P, Castro P, Ittmann M. Oxidative stress promotes benign prostatic hyperplasia. Prostate. 2016 Jan; 76(1):58-67. PMID: 26417670; PMCID: PMC5469601.
      Citations: 22     Fields:    Translation:HumansAnimals
    85. Feng S, Wang J, Zhang Y, Creighton CJ, Ittmann M, Feng S, Wang J, Zhang Y, Creighton CJ, Ittmann M. FGF23 promotes prostate cancer progression. Oncotarget. 2015 Jul 10; 6(19):17291-301. PMID: 26019137; PMCID: PMC4627308.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    86. Karatas OF, Yuceturk B, Suer I, Yilmaz M, Cansiz H, Solak M, Ittmann M, Ozen M, Karatas OF, Yuceturk B, Suer I, Yilmaz M, Cansiz H, Solak M, Ittmann M, Ozen M. Role of miR-145 in human laryngeal squamous cell carcinoma. Head Neck. 2016 Feb; 38(2):260-6. PMID: 26083661.
      Citations: 16     Fields:    Translation:HumansCells
    87. Szwarc MM, Kommagani R, Jacob AP, Dougall WC, Ittmann MM, Lydon JP, Szwarc MM, Kommagani R, Jacob AP, Dougall WC, Ittmann MM, Lydon JP. Aberrant Activation of the RANK Signaling Receptor Induces Murine Salivary Gland Tumors. PLoS One. 2015; 10(6):e0128467. PMID: 26061636; PMCID: PMC4464738.
      Citations: 4     Fields:    Translation:AnimalsCells
    88. Ayala G, Frolov A, Chatterjee D, He D, Hilsenbeck S, Ittmann M, Ayala G, Frolov A, Chatterjee D, He D, Hilsenbeck S, Ittmann M. Expression of ERG protein in prostate cancer: variability and biological correlates. Endocr Relat Cancer. 2015 Jun; 22(3):277-87. PMID: 25972242; PMCID: PMC4432248.
      Citations: 11     Fields:    Translation:Humans
    89. Ozen M, Karatas OF, Gulluoglu S, Bayrak OF, Sevli S, Guzel E, Ekici ID, Caskurlu T, Solak M, Creighton CJ, Ittmann M, Ozen M, Karatas OF, Gulluoglu S, Bayrak OF, Sevli S, Guzel E, Ekici ID, Caskurlu T, Solak M, Creighton CJ, Ittmann M. Overexpression of miR-145-5p inhibits proliferation of prostate cancer cells and reduces SOX2 expression. Cancer Invest. 2015 Jul; 33(6):251-8. PMID: 25951106.
      Citations: 44     Fields:    Translation:HumansCells
    90. Caruana I, Savoldo B, Hoyos V, Weber G, Liu H, Kim ES, Ittmann MM, Marchetti D, Dotti G, Caruana I, Savoldo B, Hoyos V, Weber G, Liu H, Kim ES, Ittmann MM, Marchetti D, Dotti G. Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes. Nat Med. 2015 May; 21(5):524-9. PMID: 25849134; PMCID: PMC4425589.
      Citations: 251     Fields:    Translation:HumansAnimalsCells
    91. Devaney JM, Wang S, Furbert-Harris P, Apprey V, Ittmann M, Wang BD, Olender J, Lee NH, Kwabi-Addo B, Devaney JM, Wang S, Furbert-Harris P, Apprey V, Ittmann M, Wang BD, Olender J, Lee NH, Kwabi-Addo B. Genome-wide differentially methylated genes in prostate cancer tissues from African-American and Caucasian men. Epigenetics. 2015; 10(4):319-28. PMID: 25864488; PMCID: PMC4622564.
      Citations: 25     Fields:    Translation:HumansCells
    92. Zhang L, Shao L, Creighton CJ, Zhang Y, Xin L, Ittmann M, Wang J, Zhang L, Shao L, Creighton CJ, Zhang Y, Xin L, Ittmann M, Wang J. Function of phosphorylation of NF-kB p65 ser536 in prostate cancer oncogenesis. Oncotarget. 2015 Mar 20; 6(8):6281-94. PMID: 25749044; PMCID: PMC4467437.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    93. Dasgupta S, Putluri N, Long W, Zhang B, Wang J, Kaushik AK, Arnold JM, Bhowmik SK, Stashi E, Brennan CA, Rajapakshe K, Coarfa C, Mitsiades N, Ittmann MM, Chinnaiyan AM, Sreekumar A, O'Malley BW, Dasgupta S, Putluri N, Long W, Zhang B, Wang J, Kaushik AK, Arnold JM, Bhowmik SK, Stashi E, Brennan CA, Rajapakshe K, Coarfa C, Mitsiades N, Ittmann MM, Chinnaiyan AM, Sreekumar A, O'Malley BW. Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis. J Clin Invest. 2015 Mar 02; 125(3):1174-88. PMID: 25664849; PMCID: PMC4362260.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    94. Higgins J, Brogley M, Palanisamy N, Mehra R, Ittmann MM, Li JZ, Tomlins SA, Robins DM, Higgins J, Brogley M, Palanisamy N, Mehra R, Ittmann MM, Li JZ, Tomlins SA, Robins DM. Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression. Horm Cancer. 2015 Jun; 6(2-3):67-86. PMID: 25631336; PMCID: PMC4414739.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    95. He B, Lanz RB, Fiskus W, Geng C, Yi P, Hartig SM, Rajapakshe K, Shou J, Wei L, Shah SS, Foley C, Chew SA, Eedunuri VK, Bedoya DJ, Feng Q, Minami T, Mitsiades CS, Frolov A, Weigel NL, Hilsenbeck SG, Rosen DG, Palzkill T, Ittmann MM, Song Y, Coarfa C, O'Malley BW, Mitsiades N, He B, Lanz RB, Fiskus W, Geng C, Yi P, Hartig SM, Rajapakshe K, Shou J, Wei L, Shah SS, Foley C, Chew SA, Eedunuri VK, Bedoya DJ, Feng Q, Minami T, Mitsiades CS, Frolov A, Weigel NL, Hilsenbeck SG, Rosen DG, Palzkill T, Ittmann MM, Song Y, Coarfa C, O'Malley BW, Mitsiades N. GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18261-6. PMID: 25489091; PMCID: PMC4280633.
      Citations: 55     Fields:    Translation:HumansCells
    96. Yang F, Chen Y, Shen T, Guo D, Dakhova O, Ittmann MM, Creighton CJ, Zhang Y, Dang TD, Rowley DR, Yang F, Chen Y, Shen T, Guo D, Dakhova O, Ittmann MM, Creighton CJ, Zhang Y, Dang TD, Rowley DR. Stromal TGF-? signaling induces AR activation in prostate cancer. Oncotarget. 2014 Nov 15; 5(21):10854-69. PMID: 25333263; PMCID: PMC4279415.
      Citations: 15     Fields:    Translation:HumansCells
    97. Candelaria NR, Addanki S, Zheng J, Nguyen-Vu T, Karaboga H, Dey P, Gabbi C, Vedin LL, Liu K, Wu W, Jonsson PK, Lin JZ, Su F, Bollu LR, Hodges SE, McElhany AL, Issazadeh MA, Fisher WE, Ittmann MM, Steffensen KR, Gustafsson JÅ, Lin CY, Candelaria NR, Addanki S, Zheng J, Nguyen-Vu T, Karaboga H, Dey P, Gabbi C, Vedin LL, Liu K, Wu W, Jonsson PK, Lin JZ, Su F, Bollu LR, Hodges SE, McElhany AL, Issazadeh MA, Fisher WE, Ittmann MM, Steffensen KR, Gustafsson JÅ, Lin CY, Gustafsson J?. Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells. PLoS One. 2014; 9(9):e106289. PMID: 25184494; PMCID: PMC4153644.
      Citations: 17     Fields:    Translation:HumansCells
    98. Guzel E, Karatas OF, Duz MB, Solak M, Ittmann M, Ozen M, Guzel E, Karatas OF, Duz MB, Solak M, Ittmann M, Ozen M. Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer. Prostate. 2014 Nov; 74(15):1498-505. PMID: 25175483.
      Citations: 23     Fields:    Translation:HumansCells
    99. Kwon OJ, Valdez JM, Zhang L, Zhang B, Wei X, Su Q, Ittmann MM, Creighton CJ, Xin L, Kwon OJ, Valdez JM, Zhang L, Zhang B, Wei X, Su Q, Ittmann MM, Creighton CJ, Xin L. Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells. Nat Commun. 2014 Jul 22; 5:4416. PMID: 25048699; PMCID: PMC4167399.
      Citations: 43     Fields:    Translation:AnimalsCells
    100. Guzel E, Karatas OF, Semercioz A, Ekici S, Aykan S, Yentur S, Creighton CJ, Ittmann M, Ozen M, Guzel E, Karatas OF, Semercioz A, Ekici S, Aykan S, Yentur S, Creighton CJ, Ittmann M, Ozen M. Identification of microRNAs differentially expressed in prostatic secretions of patients with prostate cancer. Int J Cancer. 2015 Feb 15; 136(4):875-9. PMID: 24976077.
      Citations: 25     Fields:    Translation:HumansCells
    101. Karatas OF, Guzel E, Suer I, Ekici ID, Caskurlu T, Creighton CJ, Ittmann M, Ozen M, Karatas OF, Guzel E, Suer I, Ekici ID, Caskurlu T, Creighton CJ, Ittmann M, Ozen M. miR-1 and miR-133b are differentially expressed in patients with recurrent prostate cancer. PLoS One. 2014; 9(6):e98675. PMID: 24967583; PMCID: PMC4072786.
      Citations: 44     Fields:    Translation:HumansCells
    102. Kim JS, Roberts JM, Bingman WE, Shao L, Wang J, Ittmann MM, Weigel NL, Kim JS, Roberts JM, Bingman WE, Shao L, Wang J, Ittmann MM, Weigel NL. The prostate cancer TMPRSS2:ERG fusion synergizes with the vitamin D receptor (VDR) to induce CYP24A1 expression-limiting VDR signaling. Endocrinology. 2014 Sep; 155(9):3262-73. PMID: 24926821; PMCID: PMC5377584.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    103. San Martin R, Barron DA, Tuxhorn JA, Ressler SJ, Hayward SW, Shen X, Laucirica R, Wheeler TM, Gutierrez C, Ayala GE, Ittmann M, Rowley DR, San Martin R, Barron DA, Tuxhorn JA, Ressler SJ, Hayward SW, Shen X, Laucirica R, Wheeler TM, Gutierrez C, Ayala GE, Ittmann M, Rowley DR. Recruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis. Am J Pathol. 2014 Jun; 184(6):1860-70. PMID: 24713391; PMCID: PMC4044710.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    104. Vital P, Castro P, Tsang S, Ittmann M, Vital P, Castro P, Tsang S, Ittmann M. The senescence-associated secretory phenotype promotes benign prostatic hyperplasia. Am J Pathol. 2014 Mar; 184(3):721-31. PMID: 24434012; PMCID: PMC3936307.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    105. Kwon OJ, Zhang L, Ittmann MM, Xin L, Kwon OJ, Zhang L, Ittmann MM, Xin L. Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):E592-600. PMID: 24367088; PMCID: PMC3918789.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    106. Geldres C, Savoldo B, Hoyos V, Caruana I, Zhang M, Yvon E, Del Vecchio M, Creighton CJ, Ittmann M, Ferrone S, Dotti G, Geldres C, Savoldo B, Hoyos V, Caruana I, Zhang M, Yvon E, Del Vecchio M, Creighton CJ, Ittmann M, Ferrone S, Dotti G. T lymphocytes redirected against the chondroitin sulfate proteoglycan-4 control the growth of multiple solid tumors both in vitro and in vivo. Clin Cancer Res. 2014 Feb 15; 20(4):962-71. PMID: 24334762; PMCID: PMC3944408.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    107. Carstens JL, Shahi P, Van Tsang S, Smith B, Creighton CJ, Zhang Y, Seamans A, Seethammagari M, Vedula I, Levitt JM, Ittmann MM, Rowley DR, Spencer DM, Carstens JL, Shahi P, Van Tsang S, Smith B, Creighton CJ, Zhang Y, Seamans A, Seethammagari M, Vedula I, Levitt JM, Ittmann MM, Rowley DR, Spencer DM. FGFR1-WNT-TGF-? signaling in prostate cancer mouse models recapitulates human reactive stroma. Cancer Res. 2014 Jan 15; 74(2):609-20. PMID: 24305876; PMCID: PMC3905049.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    108. Tennakoon JB, Shi Y, Han JJ, Tsouko E, White MA, Burns AR, Zhang A, Xia X, Ilkayeva OR, Xin L, Ittmann MM, Rick FG, Schally AV, Frigo DE, Tennakoon JB, Shi Y, Han JJ, Tsouko E, White MA, Burns AR, Zhang A, Xia X, Ilkayeva OR, Xin L, Ittmann MM, Rick FG, Schally AV, Frigo DE. Androgens regulate prostate cancer cell growth via an AMPK-PGC-1a-mediated metabolic switch. Oncogene. 2014 Nov 06; 33(45):5251-61. PMID: 24186207; PMCID: PMC4009392.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    109. Dakhova O, Rowley D, Ittmann M, Dakhova O, Rowley D, Ittmann M. Genes upregulated in prostate cancer reactive stroma promote prostate cancer progression in vivo. Clin Cancer Res. 2014 Jan 01; 20(1):100-9. PMID: 24150235; PMCID: PMC3947312.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    110. Ding Y, He D, Florentin D, Frolov A, Hilsenbeck S, Ittmann M, Kadmon D, Miles B, Rowley D, Ayala G, Ding Y, He D, Florentin D, Frolov A, Hilsenbeck S, Ittmann M, Kadmon D, Miles B, Rowley D, Ayala G. Semaphorin 4F as a critical regulator of neuroepithelial interactions and a biomarker of aggressive prostate cancer. Clin Cancer Res. 2013 Nov 15; 19(22):6101-11. PMID: 24097862; PMCID: PMC3898797.
      Citations: 22     Fields:    Translation:HumansCells
    111. Pan S, Cheng X, Chen H, Castro PD, Ittmann MM, Hutson AW, Zapata SK, Sifers RN, Pan S, Cheng X, Chen H, Castro PD, Ittmann MM, Hutson AW, Zapata SK, Sifers RN. ERManI is a target of miR-125b and promotes transformation phenotypes in hepatocellular carcinoma (HCC). PLoS One. 2013; 8(8):e72829. PMID: 23940818; PMCID: PMC3733964.
      Citations: 12     Fields:    Translation:HumansCells
    112. Bayrak OF, Gulluoglu S, Aydemir E, Ture U, Acar H, Atalay B, Demir Z, Sevli S, Creighton CJ, Ittmann M, Sahin F, Ozen M, Bayrak OF, Gulluoglu S, Aydemir E, Ture U, Acar H, Atalay B, Demir Z, Sevli S, Creighton CJ, Ittmann M, Sahin F, Ozen M. MicroRNA expression profiling reveals the potential function of microRNA-31 in chordomas. J Neurooncol. 2013 Nov; 115(2):143-51. PMID: 23912551.
      Citations: 28     Fields:    Translation:HumansCells
    113. Devaney JM, Wang S, Funda S, Long J, Taghipour DJ, Tbaishat R, Furbert-Harris P, Ittmann M, Kwabi-Addo B, Devaney JM, Wang S, Funda S, Long J, Taghipour DJ, Tbaishat R, Furbert-Harris P, Ittmann M, Kwabi-Addo B. Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia. Prostate Cancer Prostatic Dis. 2013 Dec; 16(4):292-300. PMID: 23896626.
      Citations: 29     Fields:    Translation:HumansCells
    114. Zhang B, Chen H, Zhang L, Dakhova O, Zhang Y, Lewis MT, Creighton CJ, Ittmann MM, Xin L, Zhang B, Chen H, Zhang L, Dakhova O, Zhang Y, Lewis MT, Creighton CJ, Ittmann MM, Xin L. A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis. Oncogene. 2014 Jun 12; 33(24):3099-108. PMID: 23851498; PMCID: PMC3916938.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    115. Tien JC, Liu Z, Liao L, Wang F, Xu Y, Wu YL, Zhou N, Ittmann M, Xu J, Tien JC, Liu Z, Liao L, Wang F, Xu Y, Wu YL, Zhou N, Ittmann M, Xu J. The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancer. Cancer Res. 2013 Jul 01; 73(13):3997-4008. PMID: 23650284; PMCID: PMC3732785.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    116. Sonpavde G, Wang M, Peterson LE, Wang HY, Joe T, Mims MP, Kadmon D, Ittmann MM, Wheeler TM, Gee AP, Wang RF, Hayes TG, Sonpavde G, Wang M, Peterson LE, Wang HY, Joe T, Mims MP, Kadmon D, Ittmann MM, Wheeler TM, Gee AP, Wang RF, Hayes TG. HLA-restricted NY-ESO-1 peptide immunotherapy for metastatic castration resistant prostate cancer. Invest New Drugs. 2014 Apr; 32(2):235-242. PMID: 23609828; PMCID: PMC4100683.
      Citations: 14     Fields:    Translation:HumansCellsCTClinical Trials
    117. Ittmann M, Huang J, Radaelli E, Martin P, Signoretti S, Sullivan R, Simons BW, Ward JM, Robinson BD, Chu GC, Loda M, Thomas G, Borowsky A, Cardiff RD, Ittmann M, Huang J, Radaelli E, Martin P, Signoretti S, Sullivan R, Simons BW, Ward JM, Robinson BD, Chu GC, Loda M, Thomas G, Borowsky A, Cardiff RD. Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee. Cancer Res. 2013 May 01; 73(9):2718-36. PMID: 23610450; PMCID: PMC3644021.
      Citations: 129     Fields:    Translation:HumansAnimals
    118. Seo YK, Mirkheshti N, Song CS, Kim S, Dodds S, Ahn SC, Christy B, Mendez-Meza R, Ittmann MM, Abboud-Werner S, Chatterjee B, Seo YK, Mirkheshti N, Song CS, Kim S, Dodds S, Ahn SC, Christy B, Mendez-Meza R, Ittmann MM, Abboud-Werner S, Chatterjee B. SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer. Mol Endocrinol. 2013 Jun; 27(6):925-39. PMID: 23579488; PMCID: PMC3656233.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    119. Yang F, Zhang Y, Ressler SJ, Ittmann MM, Ayala GE, Dang TD, Wang F, Rowley DR, Yang F, Zhang Y, Ressler SJ, Ittmann MM, Ayala GE, Dang TD, Wang F, Rowley DR. FGFR1 is essential for prostate cancer progression and metastasis. Cancer Res. 2013 Jun 15; 73(12):3716-24. PMID: 23576558; PMCID: PMC3686853.
      Citations: 41     Fields:    Translation:Animals
    120. Jin F, Irshad S, Yu W, Belakavadi M, Chekmareva M, Ittmann MM, Abate-Shen C, Fondell JD, Jin F, Irshad S, Yu W, Belakavadi M, Chekmareva M, Ittmann MM, Abate-Shen C, Fondell JD. ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity. Mol Cancer Res. 2013 Jul; 11(7):736-47. PMID: 23538858; PMCID: PMC5838364.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    121. Feng S, Dakhova O, Creighton CJ, Ittmann M, Feng S, Dakhova O, Creighton CJ, Ittmann M. Endocrine fibroblast growth factor FGF19 promotes prostate cancer progression. Cancer Res. 2013 Apr 15; 73(8):2551-62. PMID: 23440425; PMCID: PMC3630260.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    122. Ayala G, Frolov A, Ittman M, Mohammed S, LeBlanc M, Falcon S, Rowley D, Etzioni R, Ayala G, Frolov A, Ittman M, Mohammed S, LeBlanc M, Falcon S, Rowley D, Etzioni R. Biological correlates of biochemical recurrence free survival using multiple markers in a large tissue microarray cohort. Ann Clin Lab Sci. 2013; 43(1):11-21. PMID: 23462601.
      Citations: 1     Fields:    Translation:Humans
    123. Li L, Yang G, Ren C, Tanimoto R, Hirayama T, Wang J, Hawke D, Kim SM, Lee JS, Goltsov AA, Park S, Ittmann MM, Troncoso P, Thompson TC, Li L, Yang G, Ren C, Tanimoto R, Hirayama T, Wang J, Hawke D, Kim SM, Lee JS, Goltsov AA, Park S, Ittmann MM, Troncoso P, Thompson TC. Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2. Mol Oncol. 2013 Jun; 7(3):484-96. PMID: 23333597; PMCID: PMC3907183.
      Citations: 20     Fields:    Translation:HumansCells
    124. Dietrich D, Hasinger O, Bañez LL, Sun L, van Leenders GJ, Wheeler TM, Bangma CH, Wernert N, Perner S, Freedland SJ, Corman JM, Ittmann MM, Lark AL, Madden JF, Hartmann A, Schatz P, Kristiansen G, Dietrich D, Hasinger O, Bañez LL, Sun L, van Leenders GJ, Wheeler TM, Bangma CH, Wernert N, Perner S, Freedland SJ, Corman JM, Ittmann MM, Lark AL, Madden JF, Hartmann A, Schatz P, Kristiansen G, Ba?ez LL. Development and clinical validation of a real-time PCR assay for PITX2 DNA methylation to predict prostate-specific antigen recurrence in prostate cancer patients following radical prostatectomy. J Mol Diagn. 2013 Mar; 15(2):270-9. PMID: 23266319; PMCID: PMC5707187.
      Citations: 30     Fields:    Translation:HumansCells
    125. Qin J, Wu SP, Creighton CJ, Dai F, Xie X, Cheng CM, Frolov A, Ayala G, Lin X, Feng XH, Ittmann MM, Tsai SJ, Tsai MJ, Tsai SY, Qin J, Wu SP, Creighton CJ, Dai F, Xie X, Cheng CM, Frolov A, Ayala G, Lin X, Feng XH, Ittmann MM, Tsai SJ, Tsai MJ, Tsai SY. COUP-TFII inhibits TGF-?-induced growth barrier to promote prostate tumorigenesis. Nature. 2013 Jan 10; 493(7431):236-40. PMID: 23201680; PMCID: PMC4022346.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    126. Valdez JM, Zhang L, Su Q, Dakhova O, Zhang Y, Shahi P, Spencer DM, Creighton CJ, Ittmann MM, Xin L, Valdez JM, Zhang L, Su Q, Dakhova O, Zhang Y, Shahi P, Spencer DM, Creighton CJ, Ittmann MM, Xin L. Notch and TGF? form a reciprocal positive regulatory loop that suppresses murine prostate basal stem/progenitor cell activity. Cell Stem Cell. 2012 Nov 02; 11(5):676-88. PMID: 23122291; PMCID: PMC3490134.
      Citations: 47     Fields:    Translation:AnimalsCells
    127. Parta M, Hudson BY, Le TP, Ittmann M, Musher DM, Stager C, Parta M, Hudson BY, Le TP, Ittmann M, Musher DM, Stager C. IRIS iQ200 workstation as a screen for performing urine culture. Diagn Microbiol Infect Dis. 2013 Jan; 75(1):5-8. PMID: 23102549.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    128. Shao L, Tekedereli I, Wang J, Yuca E, Tsang S, Sood A, Lopez-Berestein G, Ozpolat B, Ittmann M, Shao L, Tekedereli I, Wang J, Yuca E, Tsang S, Sood A, Lopez-Berestein G, Ozpolat B, Ittmann M. Highly specific targeting of the TMPRSS2/ERG fusion gene using liposomal nanovectors. Clin Cancer Res. 2012 Dec 15; 18(24):6648-57. PMID: 23052253; PMCID: PMC3525716.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    129. Feng S, Shao L, Yu W, Gavine P, Ittmann M, Feng S, Shao L, Yu W, Gavine P, Ittmann M. Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression. Clin Cancer Res. 2012 Jul 15; 18(14):3880-8. PMID: 22573348; PMCID: PMC4654778.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    130. Cai Y, Wang J, Ren C, Ittmann M, Cai Y, Wang J, Ren C, Ittmann M. Frequent heterogeneous missense mutations of GGAP2 in prostate cancer: implications for tumor biology, clonality and mutation analysis. PLoS One. 2012; 7(2):e32708. PMID: 22389719; PMCID: PMC3289671.
      Citations: 4     Fields:    Translation:HumansCells
    131. Choi N, Zhang B, Zhang L, Ittmann M, Xin L, Choi N, Zhang B, Zhang L, Ittmann M, Xin L. Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation. Cancer Cell. 2012 Feb 14; 21(2):253-65. PMID: 22340597; PMCID: PMC3285423.
      Citations: 192     Fields:    Translation:Animals
    132. Shahi P, Park D, Pond AC, Seethammagari M, Chiou SH, Cho K, Carstens JL, Decker WK, McCrea PD, Ittmann MM, Rosen JM, Spencer DM, Shahi P, Park D, Pond AC, Seethammagari M, Chiou SH, Cho K, Carstens JL, Decker WK, McCrea PD, Ittmann MM, Rosen JM, Spencer DM. Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS One. 2012; 7(1):e30814. PMID: 22303459; PMCID: PMC3267738.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    133. Friedlander TW, Roy R, Tomlins SA, Ngo VT, Kobayashi Y, Azameera A, Rubin MA, Pienta KJ, Chinnaiyan A, Ittmann MM, Ryan CJ, Paris PL, Friedlander TW, Roy R, Tomlins SA, Ngo VT, Kobayashi Y, Azameera A, Rubin MA, Pienta KJ, Chinnaiyan A, Ittmann MM, Ryan CJ, Paris PL. Common structural and epigenetic changes in the genome of castration-resistant prostate cancer. Cancer Res. 2012 Feb 01; 72(3):616-25. PMID: 22158653.
      Citations: 57     Fields:    Translation:HumansCells
    134. Li L, Ren C, Yang G, Fattah EA, Goltsov AA, Kim SM, Lee JS, Park S, Demayo FJ, Ittmann MM, Troncoso P, Thompson TC, Li L, Ren C, Yang G, Fattah EA, Goltsov AA, Kim SM, Lee JS, Park S, Demayo FJ, Ittmann MM, Troncoso P, Thompson TC. GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction. Cancer Res. 2011 Dec 15; 71(24):7694-704. PMID: 22025562; PMCID: PMC3813470.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    135. Sonpavde G, Thompson TC, Jain RK, Ayala GE, Kurosaka S, Edamura K, Tabata K, Ren C, Goltsov AA, Mims MP, Hayes TG, Ittmann MM, Wheeler TM, Gee A, Miles BJ, Kadmon D, Sonpavde G, Thompson TC, Jain RK, Ayala GE, Kurosaka S, Edamura K, Tabata K, Ren C, Goltsov AA, Mims MP, Hayes TG, Ittmann MM, Wheeler TM, Gee A, Miles BJ, Kadmon D. GLIPR1 tumor suppressor gene expressed by adenoviral vector as neoadjuvant intraprostatic injection for localized intermediate or high-risk prostate cancer preceding radical prostatectomy. Clin Cancer Res. 2011 Nov 15; 17(22):7174-82. PMID: 21933889; PMCID: PMC3865786.
      Citations: 19     Fields:    Translation:HumansCellsCTClinical Trials
    136. Darimipourain M, Wang S, Ittmann M, Kwabi-Addo B, Darimipourain M, Wang S, Ittmann M, Kwabi-Addo B. Transcriptional and post-transcriptional regulation of Sprouty1, a receptor tyrosine kinase inhibitor in prostate cancer. Prostate Cancer Prostatic Dis. 2011 Dec; 14(4):279-85. PMID: 21826097.
      Citations: 10     Fields:    Translation:HumansCells
    137. Yin L, Rao P, Elson P, Wang J, Ittmann M, Heston WD, Yin L, Rao P, Elson P, Wang J, Ittmann M, Heston WD. Role of TMPRSS2-ERG gene fusion in negative regulation of PSMA expression. PLoS One. 2011; 6(6):e21319. PMID: 21731703; PMCID: PMC3123299.
      Citations: 10     Fields:    Translation:HumansCells
    138. Yu W, Feng S, Dakhova O, Creighton CJ, Cai Y, Wang J, Li R, Frolov A, Ayala G, Ittmann M, Yu W, Feng S, Dakhova O, Creighton CJ, Cai Y, Wang J, Li R, Frolov A, Ayala G, Ittmann M. FGFR-4 Arg?88 enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling. Clin Cancer Res. 2011 Jul 01; 17(13):4355-66. PMID: 21622724; PMCID: PMC3131485.
      Citations: 27     Fields:    Translation:HumansCells
    139. Kannan K, Wang L, Wang J, Ittmann MM, Li W, Yen L, Kannan K, Wang L, Wang J, Ittmann MM, Li W, Yen L. Recurrent chimeric RNAs enriched in human prostate cancer identified by deep sequencing. Proc Natl Acad Sci U S A. 2011 May 31; 108(22):9172-7. PMID: 21571633; PMCID: PMC3107329.
      Citations: 98     Fields:    Translation:HumansCells
    140. Ritz A, Paris PL, Ittmann MM, Collins C, Raphael BJ, Ritz A, Paris PL, Ittmann MM, Collins C, Raphael BJ. Detection of recurrent rearrangement breakpoints from copy number data. BMC Bioinformatics. 2011 Apr 21; 12:114. PMID: 21510904; PMCID: PMC3112242.
      Citations: 10     Fields:    Translation:Humans
    141. Gao Y, Ishiyama H, Sun M, Brinkman KL, Wang X, Zhu J, Mai W, Huang Y, Floryk D, Ittmann M, Thompson TC, Butler EB, Xu B, Teh BS, Gao Y, Ishiyama H, Sun M, Brinkman KL, Wang X, Zhu J, Mai W, Huang Y, Floryk D, Ittmann M, Thompson TC, Butler EB, Xu B, Teh BS. The alkylphospholipid, perifosine, radiosensitizes prostate cancer cells both in vitro and in vivo. Radiat Oncol. 2011 Apr 15; 6:39. PMID: 21496273; PMCID: PMC3096921.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    142. Agoulnik IU, Hodgson MC, Bowden WA, Ittmann MM, Agoulnik IU, Hodgson MC, Bowden WA, Ittmann MM. INPP4B: the new kid on the PI3K block. Oncotarget. 2011 Apr; 2(4):321-8. PMID: 21487159; PMCID: PMC3248162.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    143. Amirian ES, Ittmann MM, Scheurer ME, Amirian ES, Ittmann MM, Scheurer ME. Associations between arachidonic acid metabolism gene polymorphisms and prostate cancer risk. Prostate. 2011 Sep 15; 71(13):1382-9. PMID: 21308720; PMCID: PMC7339922.
      Citations: 14     Fields:    Translation:Humans
    144. Hodgson MC, Shao LJ, Frolov A, Li R, Peterson LE, Ayala G, Ittmann MM, Weigel NL, Agoulnik IU, Hodgson MC, Shao LJ, Frolov A, Li R, Peterson LE, Ayala G, Ittmann MM, Weigel NL, Agoulnik IU. Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer. Cancer Res. 2011 Jan 15; 71(2):572-82. PMID: 21224358; PMCID: PMC3077543.
      Citations: 67     Fields:    Translation:HumansCells
    145. Ayala GE, Muezzinoglu B, Hammerich KH, Frolov A, Liu H, Scardino PT, Li R, Sayeeduddin M, Ittmann MM, Kadmon D, Miles BJ, Wheeler TM, Rowley DR, Ayala GE, Muezzinoglu B, Hammerich KH, Frolov A, Liu H, Scardino PT, Li R, Sayeeduddin M, Ittmann MM, Kadmon D, Miles BJ, Wheeler TM, Rowley DR. Determining prostate cancer-specific death through quantification of stromogenic carcinoma area in prostatectomy specimens. Am J Pathol. 2011 Jan; 178(1):79-87. PMID: 21224046; PMCID: PMC3069909.
      Citations: 27     Fields:    Translation:Humans
    146. Wang J, Cai Y, Shao LJ, Siddiqui J, Palanisamy N, Li R, Ren C, Ayala G, Ittmann M, Wang J, Cai Y, Shao LJ, Siddiqui J, Palanisamy N, Li R, Ren C, Ayala G, Ittmann M. Activation of NF-{kappa}B by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4. Cancer Res. 2011 Feb 15; 71(4):1325-33. PMID: 21169414; PMCID: PMC3041849.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    147. Feng S, Agoulnik IU, Truong A, Li Z, Creighton CJ, Kaftanovskaya EM, Pereira R, Han HD, Lopez-Berestein G, Klonisch T, Ittmann MM, Sood AK, Agoulnik AI, Feng S, Agoulnik IU, Truong A, Li Z, Creighton CJ, Kaftanovskaya EM, Pereira R, Han HD, Lopez-Berestein G, Klonisch T, Ittmann MM, Sood AK, Agoulnik AI. Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis. Endocr Relat Cancer. 2010 Dec; 17(4):1021-33. PMID: 20861284.
      Citations: 25     Fields:    Translation:AnimalsCells
    148. Barron DA, Strand DW, Ressler SJ, Dang TD, Hayward SW, Yang F, Ayala GE, Ittmann M, Rowley DR, Barron DA, Strand DW, Ressler SJ, Dang TD, Hayward SW, Yang F, Ayala GE, Ittmann M, Rowley DR. TGF-?1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouse. PLoS One. 2010 Oct 29; 5(10):e13751. PMID: 21060787; PMCID: PMC2966419.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    149. Kwabi-Addo B, Wang S, Chung W, Jelinek J, Patierno SR, Wang BD, Andrawis R, Lee NH, Apprey V, Issa JP, Ittmann M, Kwabi-Addo B, Wang S, Chung W, Jelinek J, Patierno SR, Wang BD, Andrawis R, Lee NH, Apprey V, Issa JP, Ittmann M. Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men. Clin Cancer Res. 2010 Jul 15; 16(14):3539-47. PMID: 20606036.
      Citations: 65     Fields:    Translation:HumansCells
    150. Zhang L, Zhang B, Valdez JM, Wang F, Ittmann M, Xin L, Zhang L, Zhang B, Valdez JM, Wang F, Ittmann M, Xin L. Dicer ablation impairs prostate stem cell activity and causes prostate atrophy. Stem Cells. 2010 Jul; 28(7):1260-9. PMID: 20517984; PMCID: PMC3030968.
      Citations: 16     Fields:    Translation:AnimalsCells
    151. Sevli S, Uzumcu A, Solak M, Ittmann M, Ozen M, Sevli S, Uzumcu A, Solak M, Ittmann M, Ozen M. The function of microRNAs, small but potent molecules, in human prostate cancer. Prostate Cancer Prostatic Dis. 2010 Sep; 13(3):208-17. PMID: 20585343.
      Citations: 21     Fields:    Translation:Humans
    152. Bawa-Khalfe T, Cheng J, Lin SH, Ittmann MM, Yeh ET, Bawa-Khalfe T, Cheng J, Lin SH, Ittmann MM, Yeh ET. SENP1 induces prostatic intraepithelial neoplasia through multiple mechanisms. J Biol Chem. 2010 Aug 13; 285(33):25859-66. PMID: 20551310; PMCID: PMC2919148.
      Citations: 49     Fields:    Translation:HumansAnimals
    153. Bañez LL, Sun L, van Leenders GJ, Wheeler TM, Bangma CH, Freedland SJ, Ittmann MM, Lark AL, Madden JF, Hartman A, Weiss G, Castaños-Vélez E, Bañez LL, Sun L, van Leenders GJ, Wheeler TM, Bangma CH, Freedland SJ, Ittmann MM, Lark AL, Madden JF, Hartman A, Weiss G, Castaños-Vélez E, Ba?ez LL, Casta?os-V?lez E. Multicenter clinical validation of PITX2 methylation as a prostate specific antigen recurrence predictor in patients with post-radical prostatectomy prostate cancer. J Urol. 2010 Jul; 184(1):149-56. PMID: 20478579.
      Citations: 36     Fields:    Translation:HumansCells
    154. Toracchio S, Kozinetz CA, Killen DE, Sheehan AM, Banez EI, Ittmann MM, Sroller V, Butel JS, Toracchio S, Kozinetz CA, Killen DE, Sheehan AM, Banez EI, Ittmann MM, Sroller V, Butel JS. Variable frequency of polyomavirus SV40 and herpesvirus EBV in lymphomas from two different urban population groups in Houston, TX. J Clin Virol. 2009 Oct; 46(2):154-60. PMID: 19631582; PMCID: PMC2739273.
      Citations: 8     Fields:    Translation:HumansCells
    155. Dakhova O, Ozen M, Creighton CJ, Li R, Ayala G, Rowley D, Ittmann M, Dakhova O, Ozen M, Creighton CJ, Li R, Ayala G, Rowley D, Ittmann M. Global gene expression analysis of reactive stroma in prostate cancer. Clin Cancer Res. 2009 Jun 15; 15(12):3979-89. PMID: 19509179; PMCID: PMC2734921.
      Citations: 79     Fields:    Translation:HumansCells
    156. Feng S, Agoulnik IU, Li Z, Han HD, Lopez-Berestein G, Sood A, Ittmann MM, Agoulnik AI, Feng S, Agoulnik IU, Li Z, Han HD, Lopez-Berestein G, Sood A, Ittmann MM, Agoulnik AI. Relaxin/RXFP1 signaling in prostate cancer progression. Ann N Y Acad Sci. 2009 Apr; 1160:379-80. PMID: 19416223; PMCID: PMC2945500.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    157. Castro P, Creighton CJ, Ozen M, Berel D, Mims MP, Ittmann M, Castro P, Creighton CJ, Ozen M, Berel D, Mims MP, Ittmann M. Genomic profiling of prostate cancers from African American men. Neoplasia. 2009 Mar; 11(3):305-12. PMID: 19242612; PMCID: PMC2647733.
      Citations: 24     Fields:    Translation:Humans
    158. Weiss G, Cottrell S, Distler J, Schatz P, Kristiansen G, Ittmann M, Haefliger C, Lesche R, Hartmann A, Corman J, Wheeler T, Weiss G, Cottrell S, Distler J, Schatz P, Kristiansen G, Ittmann M, Haefliger C, Lesche R, Hartmann A, Corman J, Wheeler T, Weiss G, Distler J. DNA methylation of the PITX2 gene promoter region is a strong independent prognostic marker of biochemical recurrence in patients with prostate cancer after radical prostatectomy. J Urol. 2009 Apr; 181(4):1678-85. PMID: 19233404.
      Citations: 39     Fields:    Translation:HumansCells
    159. Acevedo VD, Ittmann M, Spencer DM, Acevedo VD, Ittmann M, Spencer DM. Paths of FGFR-driven tumorigenesis. Cell Cycle. 2009 Feb 15; 8(4):580-8. PMID: 19182515; PMCID: PMC7441526.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    160. Cai Y, Wang J, Li R, Ayala G, Ittmann M, Liu M, Cai Y, Wang J, Li R, Ayala G, Ittmann M, Liu M. GGAP2/PIKE-a directly activates both the Akt and nuclear factor-kappaB pathways and promotes prostate cancer progression. Cancer Res. 2009 Feb 01; 69(3):819-27. PMID: 19176382; PMCID: PMC2668918.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    161. Kwabi-Addo B, Ren C, Ittmann M, Kwabi-Addo B, Ren C, Ittmann M. DNA methylation and aberrant expression of Sprouty1 in human prostate cancer. Epigenetics. 2009 Jan; 4(1):54-61. PMID: 19164898.
      Citations: 12     Fields:    Translation:HumansCells
    162. Ayala GE, Dai H, Powell M, Li R, Ding Y, Wheeler TM, Shine D, Kadmon D, Thompson T, Miles BJ, Ittmann MM, Rowley D, Ayala GE, Dai H, Powell M, Li R, Ding Y, Wheeler TM, Shine D, Kadmon D, Thompson T, Miles BJ, Ittmann MM, Rowley D. Cancer-related axonogenesis and neurogenesis in prostate cancer. Clin Cancer Res. 2008 Dec 01; 14(23):7593-603. PMID: 19047084.
      Citations: 122     Fields:    Translation:HumansAnimalsCells
    163. Ayala G, Yan J, Li R, Ding Y, Thompson TC, Mims MP, Hayes TG, MacDonnell V, Lynch RG, Frolov A, Miles BJ, Wheeler TM, Harper JW, Tsai MJ, Ittmann MM, Kadmon D, Ayala G, Yan J, Li R, Ding Y, Thompson TC, Mims MP, Hayes TG, MacDonnell V, Lynch RG, Frolov A, Miles BJ, Wheeler TM, Harper JW, Tsai MJ, Ittmann MM, Kadmon D. Bortezomib-mediated inhibition of steroid receptor coactivator-3 degradation leads to activated Akt. Clin Cancer Res. 2008 Nov 15; 14(22):7511-8. PMID: 19010869; PMCID: PMC2820291.
      Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
    164. Wang J, Cai Y, Yu W, Ren C, Spencer DM, Ittmann M, Wang J, Cai Y, Yu W, Ren C, Spencer DM, Ittmann M. Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts. Cancer Res. 2008 Oct 15; 68(20):8516-24. PMID: 18922926; PMCID: PMC2597580.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    165. Wang J, Yu W, Cai Y, Ren C, Ittmann MM, Wang J, Yu W, Cai Y, Ren C, Ittmann MM. Altered fibroblast growth factor receptor 4 stability promotes prostate cancer progression. Neoplasia. 2008 Aug; 10(8):847-56. PMID: 18670643; PMCID: PMC2481572.
      Citations: 52     Fields:    Translation:HumansCells
    166. Lan Y, Zhang Y, Wang J, Lin C, Ittmann MM, Wang F, Lan Y, Zhang Y, Wang J, Lin C, Ittmann MM, Wang F. Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death. Int J Cancer. 2008 Aug 01; 123(3):543-51. PMID: 18498131; PMCID: PMC3262990.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    167. Yan J, Erdem H, Li R, Cai Y, Ayala G, Ittmann M, Yu-Lee LY, Tsai SY, Tsai MJ, Yan J, Erdem H, Li R, Cai Y, Ayala G, Ittmann M, Yu-Lee LY, Tsai SY, Tsai MJ. Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression. Cancer Res. 2008 Jul 01; 68(13):5460-8. PMID: 18593949; PMCID: PMC2826835.
      Citations: 61     Fields:    Translation:HumansCells
    168. Chung W, Kwabi-Addo B, Ittmann M, Jelinek J, Shen L, Yu Y, Issa JP, Chung W, Kwabi-Addo B, Ittmann M, Jelinek J, Shen L, Yu Y, Issa JP. Identification of novel tumor markers in prostate, colon and breast cancer by unbiased methylation profiling. PLoS One. 2008 Apr 30; 3(4):e2079. PMID: 18446232; PMCID: PMC2323612.
      Citations: 52     Fields:    Translation:HumansCells
    169. Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F, Ayala GE, Peterson LE, Ittmann M, Spencer DM, Acevedo VD, Gangula RD, Freeman KW, Li R, Zhang Y, Wang F, Ayala GE, Peterson LE, Ittmann M, Spencer DM. Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition. Cancer Cell. 2007 Dec; 12(6):559-71. PMID: 18068632.
      Citations: 148     Fields:    Translation:HumansAnimalsCells
    170. Ozen M, Creighton CJ, Ozdemir M, Ittmann M, Ozen M, Creighton CJ, Ozdemir M, Ittmann M. Widespread deregulation of microRNA expression in human prostate cancer. Oncogene. 2008 Mar 13; 27(12):1788-93. PMID: 17891175.
      Citations: 317     Fields:    Translation:HumansCells
    171. Shao TC, Li H, Ittmann M, Cunningham GR, Shao TC, Li H, Ittmann M, Cunningham GR. Effects of dutasteride on prostate growth in the large probasin-large T antigen mouse model of prostate cancer. J Urol. 2007 Oct; 178(4 Pt 1):1521-7. PMID: 17707058.
      Citations: 5     Fields:    Translation:Animals
    172. Shafer J, Davis AR, Gannon FH, Fouletier-Dilling CM, Lazard Z, Moran K, Gugala Z, Ozen M, Ittmann M, Heggeness MH, Olmsted-Davis E, Shafer J, Davis AR, Gannon FH, Fouletier-Dilling CM, Lazard Z, Moran K, Gugala Z, Ozen M, Ittmann M, Heggeness MH, Olmsted-Davis E. Oxygen tension directs chondrogenic differentiation of myelo-monocytic progenitors during endochondral bone formation. Tissue Eng. 2007 Aug; 13(8):2011-9. PMID: 17518751.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    173. Kwabi-Addo B, Chung W, Shen L, Ittmann M, Wheeler T, Jelinek J, Issa JP, Kwabi-Addo B, Chung W, Shen L, Ittmann M, Wheeler T, Jelinek J, Issa JP. Age-related DNA methylation changes in normal human prostate tissues. Clin Cancer Res. 2007 Jul 01; 13(13):3796-802. PMID: 17606710.
      Citations: 89     Fields:    Translation:HumansCells
    174. Cottrell S, Jung K, Kristiansen G, Eltze E, Semjonow A, Ittmann M, Hartmann A, Stamey T, Haefliger C, Weiss G, Cottrell S, Jung K, Kristiansen G, Eltze E, Semjonow A, Ittmann M, Hartmann A, Stamey T, Haefliger C, Weiss G. Discovery and validation of 3 novel DNA methylation markers of prostate cancer prognosis. J Urol. 2007 May; 177(5):1753-8. PMID: 17437806.
      Citations: 41     Fields:    Translation:HumansCells
    175. Feng S, Agoulnik IU, Bogatcheva NV, Kamat AA, Kwabi-Addo B, Li R, Ayala G, Ittmann MM, Agoulnik AI, Feng S, Agoulnik IU, Bogatcheva NV, Kamat AA, Kwabi-Addo B, Li R, Ayala G, Ittmann MM, Agoulnik AI. Relaxin promotes prostate cancer progression. Clin Cancer Res. 2007 Mar 15; 13(6):1695-702. PMID: 17363522.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    176. Olmsted-Davis E, Gannon FH, Ozen M, Ittmann MM, Gugala Z, Hipp JA, Moran KM, Fouletier-Dilling CM, Schumara-Martin S, Lindsey RW, Heggeness MH, Brenner MK, Davis AR, Olmsted-Davis E, Gannon FH, Ozen M, Ittmann MM, Gugala Z, Hipp JA, Moran KM, Fouletier-Dilling CM, Schumara-Martin S, Lindsey RW, Heggeness MH, Brenner MK, Davis AR. Hypoxic adipocytes pattern early heterotopic bone formation. Am J Pathol. 2007 Feb; 170(2):620-32. PMID: 17255330; PMCID: PMC1851874.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    177. Yan J, Yu CT, Ozen M, Ittmann M, Tsai SY, Tsai MJ, Yan J, Yu CT, Ozen M, Ittmann M, Tsai SY, Tsai MJ. Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway. Cancer Res. 2006 Nov 15; 66(22):11039-46. PMID: 17108143.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    178. Dai H, Li R, Wheeler T, Ozen M, Ittmann M, Anderson M, Wang Y, Rowley D, Younes M, Ayala GE, Dai H, Li R, Wheeler T, Ozen M, Ittmann M, Anderson M, Wang Y, Rowley D, Younes M, Ayala GE. Enhanced survival in perineural invasion of pancreatic cancer: an in vitro approach. Hum Pathol. 2007 Feb; 38(2):299-307. PMID: 17097719.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    179. Agoulnik IU, Vaid A, Nakka M, Alvarado M, Bingman WE, Erdem H, Frolov A, Smith CL, Ayala GE, Ittmann MM, Weigel NL, Agoulnik IU, Vaid A, Nakka M, Alvarado M, Bingman WE, Erdem H, Frolov A, Smith CL, Ayala GE, Ittmann MM, Weigel NL. Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer. Cancer Res. 2006 Nov 01; 66(21):10594-602. PMID: 17079484.
      Citations: 89     Fields:    Translation:HumansCells
    180. Wang J, Cai Y, Penland R, Chauhan S, Miesfeld RL, Ittmann M, Wang J, Cai Y, Penland R, Chauhan S, Miesfeld RL, Ittmann M. Increased expression of the metastasis-associated gene Ehm2 in prostate cancer. Prostate. 2006 Nov 01; 66(15):1641-52. PMID: 16927306.
      Citations: 11     Fields:    Translation:HumansCells
    181. De Marzo AM, Platz EA, Epstein JI, Ali T, Billis A, Chan TY, Cheng L, Datta M, Egevad L, Ertoy-Baydar D, Farre X, Farree X, Fine SW, Iczkowski KA, Ittmann M, Knudsen BS, Loda M, Lopez-Beltran A, Magi-Galluzzi C, Mikuz G, Montironi R, Pikarsky E, Pizov G, Rubin MA, Samaratunga H, Sebo T, Sesterhenn IA, Shah RB, Shah RB, Signoretti S, Simko J, Thomas G, Troncoso P, Tsuzuki TT, van Leenders GJ, Yang XJ, Zhou M, Figg WD, Hoque A, Hoque A, Lucia MS, De Marzo AM, Platz EA, Epstein JI, Ali T, Billis A, Chan TY, Cheng L, Datta M, Egevad L, Ertoy-Baydar D, Farre X, Farree X, Fine SW, Iczkowski KA, Ittmann M, Knudsen BS, Loda M, Lopez-Beltran A, Magi-Galluzzi C, Mikuz G, Montironi R, Pikarsky E, Pizov G, Rubin MA, Samaratunga H, Sebo T, Sesterhenn IA, Shah RB, Shah RB, Signoretti S, Simko J, Thomas G, Troncoso P, Tsuzuki TT, van Leenders GJ, Yang XJ, Zhou M, Figg WD, Hoque A, Hoque A, Lucia MS. A working group classification of focal prostate atrophy lesions. Am J Surg Pathol. 2006 Oct; 30(10):1281-91. PMID: 17001160.
      Citations: 28     Fields:    Translation:Humans
    182. Wang J, Cai Y, Ren C, Ittmann M, Wang J, Cai Y, Ren C, Ittmann M. Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer. Cancer Res. 2006 Sep 01; 66(17):8347-51. PMID: 16951141.
      Citations: 167     Fields:    Translation:HumansCells
    183. Wang J, Weng J, Cai Y, Penland R, Liu M, Ittmann M, Wang J, Weng J, Cai Y, Penland R, Liu M, Ittmann M. The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase. Prostate. 2006 Jun 01; 66(8):847-57. PMID: 16491480.
      Citations: 25     Fields:    Translation:Humans
    184. Ayala GE, Dai H, Tahir SA, Li R, Timme T, Ittmann M, Frolov A, Wheeler TM, Rowley D, Thompson TC, Ayala GE, Dai H, Tahir SA, Li R, Timme T, Ittmann M, Frolov A, Wheeler TM, Rowley D, Thompson TC. Stromal antiapoptotic paracrine loop in perineural invasion of prostatic carcinoma. Cancer Res. 2006 May 15; 66(10):5159-64. PMID: 16707439.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    185. Wang J, Thompson B, Ren C, Ittmann M, Kwabi-Addo B, Wang J, Thompson B, Ren C, Ittmann M, Kwabi-Addo B. Sprouty4, a suppressor of tumor cell motility, is down regulated by DNA methylation in human prostate cancer. Prostate. 2006 May 01; 66(6):613-24. PMID: 16388505.
      Citations: 37     Fields:    Translation:HumansCells
    186. Weng J, Wang J, Hu X, Wang F, Ittmann M, Liu M, Weng J, Wang J, Hu X, Wang F, Ittmann M, Liu M. PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer. Int J Cancer. 2006 Mar 15; 118(6):1471-80. PMID: 16206286.
      Citations: 29     Fields:    Translation:HumansCells
    187. Shao TC, Li HL, Kasper S, Matusik R, Ittmann M, Cunningham GR, Shao TC, Li HL, Kasper S, Matusik R, Ittmann M, Cunningham GR. Comparison of the growth-promoting effects of testosterone and 7-alpha-methyl-19-nor-testosterone (MENT) on the prostate and levator ani muscle of LPB-tag transgenic mice. Prostate. 2006 Mar 01; 66(4):369-76. PMID: 16302273.
      Citations: 3     Fields:    Translation:Animals
    188. Ayala GE, Dai H, Li R, Ittmann M, Thompson TC, Rowley D, Wheeler TM, Ayala GE, Dai H, Li R, Ittmann M, Thompson TC, Rowley D, Wheeler TM. Bystin in perineural invasion of prostate cancer. Prostate. 2006 Feb 15; 66(3):266-72. PMID: 16245277.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    189. Mims MP, Hayes TG, Zheng S, Leal SM, Frolov A, Ittmann MM, Wheeler TM, Prchal JT, Mims MP, Hayes TG, Zheng S, Leal SM, Frolov A, Ittmann MM, Wheeler TM, Prchal JT. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res. 2006 Feb 01; 66(3):1880; author reply 1880-1. PMID: 16452251; PMCID: PMC6181229.
      Citations: 33     Fields:    Translation:Humans
    190. Koh MS, Ittmann M, Kadmon D, Thompson TC, Leach FS, Koh MS, Ittmann M, Kadmon D, Thompson TC, Leach FS. CDC4 gene expression as potential biomarker for targeted therapy in prostate cancer. Cancer Biol Ther. 2006 Jan; 5(1):78-83. PMID: 16357515.
      Citations: 14     Fields:    Translation:Humans
    191. Cai Y, Wu P, Ozen M, Yu Y, Wang J, Ittmann M, Liu M, Cai Y, Wu P, Ozen M, Yu Y, Wang J, Ittmann M, Liu M. Gene expression profiling and analysis of signaling pathways involved in priming and differentiation of human neural stem cells. Neuroscience. 2006; 138(1):133-48. PMID: 16414199.
      Citations: 7     Fields:    Translation:HumansCells
    192. Zhou HJ, Yan J, Luo W, Ayala G, Lin SH, Erdem H, Ittmann M, Tsai SY, Tsai MJ, Zhou HJ, Yan J, Luo W, Ayala G, Lin SH, Erdem H, Ittmann M, Tsai SY, Tsai MJ. SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res. 2005 Sep 01; 65(17):7976-83. PMID: 16140970.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    193. Agoulnik IU, Vaid A, Bingman WE, Erdeme H, Frolov A, Smith CL, Ayala G, Ittmann MM, Weigel NL, Agoulnik IU, Vaid A, Bingman WE, Erdeme H, Frolov A, Smith CL, Ayala G, Ittmann MM, Weigel NL. Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression. Cancer Res. 2005 Sep 01; 65(17):7959-67. PMID: 16140968.
      Citations: 90     Fields:    Translation:HumansCells
    194. Ozen M, Ittmann M, Ozen M, Ittmann M. Increased expression and activity of CDC25C phosphatase and an alternatively spliced variant in prostate cancer. Clin Cancer Res. 2005 Jul 01; 11(13):4701-6. PMID: 16000564.
      Citations: 33     Fields:    Translation:HumansCells
    195. Weng J, Wang J, Cai Y, Stafford LJ, Mitchell D, Ittmann M, Liu M, Weng J, Wang J, Cai Y, Stafford LJ, Mitchell D, Ittmann M, Liu M. Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers. Int J Cancer. 2005 Feb 20; 113(5):811-8. PMID: 15499628.
      Citations: 20     Fields:    Translation:Humans
    196. Han G, Buchanan G, Ittmann M, Harris JM, Yu X, Demayo FJ, Tilley W, Greenberg NM, Han G, Buchanan G, Ittmann M, Harris JM, Yu X, Demayo FJ, Tilley W, Greenberg NM. Mutation of the androgen receptor causes oncogenic transformation of the prostate. Proc Natl Acad Sci U S A. 2005 Jan 25; 102(4):1151-6. PMID: 15657128; PMCID: PMC544619.
      Citations: 63     Fields:    Translation:AnimalsCells
    197. Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC, Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC. The emerging role of the PI3-K-Akt pathway in prostate cancer progression. Prostate Cancer Prostatic Dis. 2005; 8(2):108-18. PMID: 15724144.
      Citations: 54     Fields:    Translation:HumansCells
    198. Kwabi-Addo B, Ozen M, Ittmann M, Kwabi-Addo B, Ozen M, Ittmann M. The role of fibroblast growth factors and their receptors in prostate cancer. Endocr Relat Cancer. 2004 Dec; 11(4):709-24. PMID: 15613447.
      Citations: 129     Fields:    Translation:HumansCells
    199. Velasco A, Riquelme E, Schultz M, Wistuba II, Villarroel L, Pizarro J, Berlin A, Ittmann M, Koh MS, Leach FS, Velasco A, Riquelme E, Schultz M, Wistuba II, Villarroel L, Pizarro J, Berlin A, Ittmann M, Koh MS, Leach FS. Mismatch repair gene expression and genetic instability in testicular germ cell tumor. Cancer Biol Ther. 2004 Oct; 3(10):977-82. PMID: 15467433.
      Citations: 6     Fields:    Translation:HumansCells
    200. Wang J, Stockton DW, Ittmann M, Wang J, Stockton DW, Ittmann M. The fibroblast growth factor receptor-4 Arg388 allele is associated with prostate cancer initiation and progression. Clin Cancer Res. 2004 Sep 15; 10(18 Pt 1):6169-78. PMID: 15448004.
      Citations: 65     Fields:    Translation:HumansCells
    201. Ayala GE, Dai H, Ittmann M, Li R, Powell M, Frolov A, Wheeler TM, Thompson TC, Rowley D, Ayala GE, Dai H, Ittmann M, Li R, Powell M, Frolov A, Wheeler TM, Thompson TC, Rowley D. Growth and survival mechanisms associated with perineural invasion in prostate cancer. Cancer Res. 2004 Sep 01; 64(17):6082-90. PMID: 15342391.
      Citations: 79     Fields:    Translation:HumansCells
    202. Kwabi-Addo B, Wang J, Erdem H, Vaid A, Castro P, Ayala G, Ittmann M, Kwabi-Addo B, Wang J, Erdem H, Vaid A, Castro P, Ayala G, Ittmann M. The expression of Sprouty1, an inhibitor of fibroblast growth factor signal transduction, is decreased in human prostate cancer. Cancer Res. 2004 Jul 15; 64(14):4728-35. PMID: 15256439.
      Citations: 57     Fields:    Translation:HumansCells
    203. Castro P, Xia C, Gomez L, Lamb DJ, Ittmann M, Castro P, Xia C, Gomez L, Lamb DJ, Ittmann M. Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasia. Prostate. 2004 Jul 01; 60(2):153-9. PMID: 15162381.
      Citations: 40     Fields:    Translation:HumansCells
    204. Polnaszek N, Kwabi-Addo B, Wang J, Ittmann M, Polnaszek N, Kwabi-Addo B, Wang J, Ittmann M. FGF17 is an autocrine prostatic epithelial growth factor and is upregulated in benign prostatic hyperplasia. Prostate. 2004 Jun 15; 60(1):18-24. PMID: 15129425.
      Citations: 9     Fields:    Translation:HumansCells
    205. Kinsey BM, Marcelli M, Song L, Bhogal BS, Ittmann M, Orson FM, Kinsey BM, Marcelli M, Song L, Bhogal BS, Ittmann M, Orson FM. Enhancement of both cellular and humoral responses to genetic immunization by co-administration of an antigen-expressing plasmid and a plasmid encoding the pro-apoptotic protein Bax. J Gene Med. 2004 Apr; 6(4):445-54. PMID: 15079819.
      Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    206. Shappell SB, Thomas GV, Roberts RL, Herbert R, Ittmann MM, Rubin MA, Humphrey PA, Sundberg JP, Rozengurt N, Barrios R, Ward JM, Cardiff RD, Shappell SB, Thomas GV, Roberts RL, Herbert R, Ittmann MM, Rubin MA, Humphrey PA, Sundberg JP, Rozengurt N, Barrios R, Ward JM, Cardiff RD. Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee. Cancer Res. 2004 Mar 15; 64(6):2270-305. PMID: 15026373.
      Citations: 254     Fields:    Translation:HumansAnimals
    207. Ozen M, Medrano EE, Ittmann M, Ozen M, Medrano EE, Ittmann M. Inhibition of proliferation and survival of melanoma cells by adenoviral-mediated expression of dominant negative fibroblast growth factor receptor. Melanoma Res. 2004 Feb; 14(1):13-21. PMID: 15091189.
      Citations: 11     Fields:    Translation:HumansCells
    208. Ren C, Li L, Yang G, Timme TL, Goltsov A, Ren C, Ji X, Addai J, Luo H, Ittmann MM, Thompson TC, Ren C, Li L, Yang G, Timme TL, Goltsov A, Ren C, Ji X, Addai J, Luo H, Ittmann MM, Thompson TC. RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer. Cancer Res. 2004 Feb 01; 64(3):969-76. PMID: 14871827.
      Citations: 31     Fields:    Translation:HumansCells
    209. Wang F, McKeehan K, Yu C, Ittmann M, McKeehan WL, Wang F, McKeehan K, Yu C, Ittmann M, McKeehan WL. Chronic activity of ectopic type 1 fibroblast growth factor receptor tyrosine kinase in prostate epithelium results in hyperplasia accompanied by intraepithelial neoplasia. Prostate. 2004 Jan 01; 58(1):1-12. PMID: 14673947.
      Citations: 19     Fields:    Translation:AnimalsCells
    210. Jin C, McKeehan K, Guo W, Jauma S, Ittmann MM, Foster B, Greenberg NM, McKeehan WL, Wang F, Jin C, McKeehan K, Guo W, Jauma S, Ittmann MM, Foster B, Greenberg NM, McKeehan WL, Wang F. Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate. Cancer Res. 2003 Dec 15; 63(24):8784-90. PMID: 14695195.
      Citations: 23     Fields:    Translation:AnimalsCells
    211. Freeman KW, Welm BE, Gangula RD, Rosen JM, Ittmann M, Greenberg NM, Spencer DM, Freeman KW, Welm BE, Gangula RD, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. Cancer Res. 2003 Dec 01; 63(23):8256-63. PMID: 14678983.
      Citations: 30     Fields:    Translation:AnimalsCells
    212. Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, Ittmann M, Greenberg NM, Spencer DM, Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation. Cancer Res. 2003 Oct 01; 63(19):6237-43. PMID: 14559809.
      Citations: 32     Fields:    Translation:AnimalsCells
    213. Shao TC, Li H, Eid W, Ittmann M, Unni E, Cunningham GR, Shao TC, Li H, Eid W, Ittmann M, Unni E, Cunningham GR. In vivo preservation of steroid specificity in CWR22 xenografts having a mutated androgen receptor. Prostate. 2003 Sep 15; 57(1):1-7. PMID: 12886517.
      Citations:    Fields:    Translation:Animals
    214. Polnaszek N, Kwabi-Addo B, Peterson LE, Ozen M, Greenberg NM, Ortega S, Basilico C, Ittmann M, Polnaszek N, Kwabi-Addo B, Peterson LE, Ozen M, Greenberg NM, Ortega S, Basilico C, Ittmann M. Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer. Cancer Res. 2003 Sep 15; 63(18):5754-60. PMID: 14522896.
      Citations: 40     Fields:    Translation:AnimalsCells
    215. Li M, Ittmann MM, Rowley DR, Knowlton AA, Vaid AK, Epner DE, Li M, Ittmann MM, Rowley DR, Knowlton AA, Vaid AK, Epner DE. Glutathione S-transferase pi is upregulated in the stromal compartment of hormone independent prostate cancer. Prostate. 2003 Jul 01; 56(2):98-105. PMID: 12746833.
      Citations: 1     Fields:    Translation:HumansCells
    216. Kaplan-Lefko PJ, Chen TM, Ittmann MM, Barrios RJ, Ayala GE, Huss WJ, Maddison LA, Foster BA, Greenberg NM, Kaplan-Lefko PJ, Chen TM, Ittmann MM, Barrios RJ, Ayala GE, Huss WJ, Maddison LA, Foster BA, Greenberg NM. Pathobiology of autochthonous prostate cancer in a pre-clinical transgenic mouse model. Prostate. 2003 May 15; 55(3):219-37. PMID: 12692788.
      Citations: 179     Fields:    Translation:HumansAnimals
    217. Castro P, Giri D, Lamb D, Ittmann M, Castro P, Giri D, Lamb D, Ittmann M. Cellular senescence in the pathogenesis of benign prostatic hyperplasia. Prostate. 2003 Apr 01; 55(1):30-8. PMID: 12640658.
      Citations: 59     Fields:    Translation:HumansCells
    218. Mouraviev V, Li L, Tahir SA, Yang G, Timme TM, Goltsov A, Ren C, Satoh T, Wheeler TM, Ittmann MM, Miles BJ, Amato RJ, Kadmon D, Thompson TC, Mouraviev V, Li L, Tahir SA, Yang G, Timme TM, Goltsov A, Ren C, Satoh T, Wheeler TM, Ittmann MM, Miles BJ, Amato RJ, Kadmon D, Thompson TC. The role of caveolin-1 in androgen insensitive prostate cancer. J Urol. 2002 Oct; 168(4 Pt 1):1589-96. PMID: 12352463.
      Citations: 17     Fields:    Translation:HumansAnimals
    219. Vlachaki MT, Hernandez-Garcia A, Ittmann M, Chhikara M, Aguilar LK, Zhu X, Teh BS, Butler EB, Woo S, Thompson TC, Barrera-Saldana H, Aguilar-Cordova E, The BS, Vlachaki MT, Hernandez-Garcia A, Ittmann M, Chhikara M, Aguilar LK, Zhu X, Teh BS, Butler EB, Woo S, Thompson TC, Barrera-Saldana H, Aguilar-Cordova E, The BS. Impact of preimmunization on adenoviral vector expression and toxicity in a subcutaneous mouse cancer model. Mol Ther. 2002 Sep; 6(3):342-8. PMID: 12231170.
      Citations: 19     Fields:    Translation:AnimalsCellsPHPublic Health
    220. Ozen M, Giri D, Ropiquet F, Mansukhani A, Ittmann M, Ozen M, Giri D, Ropiquet F, Mansukhani A, Ittmann M. Role of fibroblast growth factor receptor signaling in prostate cancer cell survival. J Natl Cancer Inst. 2001 Dec 05; 93(23):1783-90. PMID: 11734594.
      Citations: 24     Fields:    Translation:HumansCells
    221. Giri D, Ozen M, Ittmann M, Giri D, Ozen M, Ittmann M. Interleukin-6 is an autocrine growth factor in human prostate cancer. Am J Pathol. 2001 Dec; 159(6):2159-65. PMID: 11733366; PMCID: PMC1850613.
      Citations: 100     Fields:    Translation:HumansCells
    222. Kwabi-Addo B, Giri D, Schmidt K, Podsypanina K, Parsons R, Greenberg N, Ittmann M, Kwabi-Addo B, Giri D, Schmidt K, Podsypanina K, Parsons R, Greenberg N, Ittmann M. Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression. Proc Natl Acad Sci U S A. 2001 Sep 25; 98(20):11563-8. PMID: 11553783; PMCID: PMC58769.
      Citations: 113     Fields:    Translation:HumansAnimals
    223. Giri D, Ittmann M, Giri D, Ittmann M. Interleukin-8 is a paracrine inducer of fibroblast growth factor 2, a stromal and epithelial growth factor in benign prostatic hyperplasia. Am J Pathol. 2001 Jul; 159(1):139-47. PMID: 11438462; PMCID: PMC1850405.
      Citations: 59     Fields:    Translation:HumansCells
    224. Tahir SA, Yang G, Ebara S, Timme TL, Satoh T, Li L, Goltsov A, Ittmann M, Morrisett JD, Thompson TC, Tahir SA, Yang G, Ebara S, Timme TL, Satoh T, Li L, Goltsov A, Ittmann M, Morrisett JD, Thompson TC. Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer. Cancer Res. 2001 May 15; 61(10):3882-5. PMID: 11358800.
      Citations: 77     Fields:    Translation:HumansAnimals
    225. Kwabi-Addo B, Ropiquet F, Giri D, Ittmann M, Kwabi-Addo B, Ropiquet F, Giri D, Ittmann M. Alternative splicing of fibroblast growth factor receptors in human prostate cancer. Prostate. 2001 Feb 01; 46(2):163-72. PMID: 11170144.
      Citations: 28     Fields:    Translation:HumansCells
    226. Yang G, Addai J, Ittmann M, Wheeler TM, Thompson TC, Yang G, Addai J, Ittmann M, Wheeler TM, Thompson TC. Elevated caveolin-1 levels in African-American versus white-American prostate cancer. Clin Cancer Res. 2000 Sep; 6(9):3430-3. PMID: 10999725.
      Citations: 13     Fields:    Translation:Humans
    227. Ropiquet F, Giri D, Kwabi-Addo B, Schmidt K, Ittmann M, Ropiquet F, Giri D, Kwabi-Addo B, Schmidt K, Ittmann M. FGF-10 is expressed at low levels in the human prostate. Prostate. 2000 Sep 01; 44(4):334-8. PMID: 10951499.
      Citations: 3     Fields:    Translation:HumansCells
    228. Ropiquet F, Giri D, Kwabi-Addo B, Mansukhani A, Ittmann M, Ropiquet F, Giri D, Kwabi-Addo B, Mansukhani A, Ittmann M. Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. Cancer Res. 2000 Aug 01; 60(15):4245-50. PMID: 10945637.
      Citations: 28     Fields:    Translation:HumansCells
    229. Giri D, Ittmann M, Giri D, Ittmann M. Interleukin-1alpha is a paracrine inducer of FGF7, a key epithelial growth factor in benign prostatic hyperplasia. Am J Pathol. 2000 Jul; 157(1):249-55. PMID: 10880394; PMCID: PMC1850193.
      Citations: 27     Fields:    Translation:HumansCells
    230. Kwabi-Addo B, Thompson TC, Ittmann M, Kwabi-Addo B, Thompson TC, Ittmann M. Absence of PTEN/MMAC1 pseudogene in mice. DNA Cell Biol. 2000 May; 19(5):301-5. PMID: 10855797.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    231. Marcelli M, Ittmann M, Mariani S, Sutherland R, Nigam R, Murthy L, Zhao Y, DiConcini D, Puxeddu E, Esen A, Eastham J, Weigel NL, Lamb DJ, Marcelli M, Ittmann M, Mariani S, Sutherland R, Nigam R, Murthy L, Zhao Y, DiConcini D, Puxeddu E, Esen A, Eastham J, Weigel NL, Lamb DJ. Androgen receptor mutations in prostate cancer. Cancer Res. 2000 Feb 15; 60(4):944-9. PMID: 10706109.
      Citations: 79     Fields:    Translation:Humans
    232. Nastiuk KL, Mansukhani M, Terry MB, Kularatne P, Rubin MA, Melamed J, Gammon MD, Ittmann M, Krolewski JJ, Nastiuk KL, Mansukhani M, Terry MB, Kularatne P, Rubin MA, Melamed J, Gammon MD, Ittmann M, Krolewski JJ. Common mutations in BRCA1 and BRCA2 do not contribute to early prostate cancer in Jewish men. Prostate. 1999 Aug 01; 40(3):172-7. PMID: 10398279; PMCID: PMC4196372.
      Citations: 18     Fields:    Translation:Humans
    233. Ropiquet F, Giri D, Lamb DJ, Ittmann M, Ropiquet F, Giri D, Lamb DJ, Ittmann M. FGF7 and FGF2 are increased in benign prostatic hyperplasia and are associated with increased proliferation. J Urol. 1999 Aug; 162(2):595-9. PMID: 10411093.
      Citations: 22     Fields:    Translation:HumansCells
    234. Giri D, Ropiquet F, Ittmann M, Giri D, Ropiquet F, Ittmann M. FGF9 is an autocrine and paracrine prostatic growth factor expressed by prostatic stromal cells. J Cell Physiol. 1999 Jul; 180(1):53-60. PMID: 10362017.
      Citations: 21     Fields:    Translation:HumansCells
    235. Giri D, Ropiquet F, Ittmann M, Giri D, Ropiquet F, Ittmann M. Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer. Clin Cancer Res. 1999 May; 5(5):1063-71. PMID: 10353739.
      Citations: 92     Fields:    Translation:HumansCells
    236. Walden PD, Lefkowitz GK, Ittmann M, Lepor H, Monaco ME, Walden PD, Lefkowitz GK, Ittmann M, Lepor H, Monaco ME. Mitogenic activation of human prostate-derived fibromuscular stromal cells by bradykinin. Br J Pharmacol. 1999 May; 127(1):220-6. PMID: 10369476; PMCID: PMC1565979.
      Citations: 2     Fields:    Translation:HumansCells
    237. Giri D, Ittmann M, Giri D, Ittmann M. Inactivation of the PTEN tumor suppressor gene is associated with increased angiogenesis in clinically localized prostate carcinoma. Hum Pathol. 1999 Apr; 30(4):419-24. PMID: 10208463.
      Citations: 21     Fields:    Translation:Humans
    238. Ittmann MM, Ittmann MM. Chromosome 10 alterations in prostate adenocarcinoma (review). Oncol Rep. 1998 Nov-Dec; 5(6):1329-35. PMID: 9769364.
      Citations: 17     Fields:    Translation:HumansCells
    239. Ortega S, Ittmann M, Tsang SH, Ehrlich M, Basilico C, Ortega S, Ittmann M, Tsang SH, Ehrlich M, Basilico C. Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2. Proc Natl Acad Sci U S A. 1998 May 12; 95(10):5672-7. PMID: 9576942; PMCID: PMC20437.
      Citations: 164     Fields:    Translation:AnimalsCells
    240. Walden PD, Ittmann M, Monaco ME, Lepor H, Walden PD, Ittmann M, Monaco ME, Lepor H. Endothelin-1 production and agonist activities in cultured prostate-derived cells: implications for regulation of endothelin bioactivity and bioavailability in prostatic hyperplasia. Prostate. 1998 Mar 01; 34(4):241-50. PMID: 9496898.
      Citations: 11     Fields:    Translation:HumansCells
    241. Wang SI, Parsons R, Ittmann M, Wang SI, Parsons R, Ittmann M. Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas. Clin Cancer Res. 1998 Mar; 4(3):811-5. PMID: 9533551.
      Citations: 67     Fields:    Translation:HumansCells
    242. Singh B, Ittmann MM, Krolewski JJ, Singh B, Ittmann MM, Krolewski JJ. Sporadic breast cancers exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden disease locus. Genes Chromosomes Cancer. 1998 Feb; 21(2):166-71. PMID: 9491329.
      Citations: 31     Fields:    Translation:HumansCells
    243. Levine MA, Ittman M, Melamed J, Lepor H, Levine MA, Ittman M, Melamed J, Lepor H. Two consecutive sets of transrectal ultrasound guided sextant biopsies of the prostate for the detection of prostate cancer. J Urol. 1998 Feb; 159(2):471-5; discussion 475-6. PMID: 9649265.
      Citations: 71     Fields:    Translation:HumansCTClinical Trials
    244. Melamed J, Einhorn JM, Ittmann MM, Melamed J, Einhorn JM, Ittmann MM. Allelic loss on chromosome 13q in human prostate carcinoma. Clin Cancer Res. 1997 Oct; 3(10):1867-72. PMID: 9815575.
      Citations: 17     Fields:    Translation:HumansCells
    245. Liu W, Ittmann M, Liu J, Schoentag R, Tierno P, Greco MA, Sidhu G, Nierodzik M, Wieczorek R, Liu W, Ittmann M, Liu J, Schoentag R, Tierno P, Greco MA, Sidhu G, Nierodzik M, Wieczorek R. Human parvovirus B19 in bone marrows from adults with acquired immunodeficiency syndrome: a comparative study using in situ hybridization and immunohistochemistry. Hum Pathol. 1997 Jul; 28(7):760-6. PMID: 9224741.
      Citations: 3     Fields:    Translation:HumansCells
    246. Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R, Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science. 1997 Mar 28; 275(5308):1943-7. PMID: 9072974.
      Citations: 1590     Fields:    Translation:HumansCells
    247. Jacobson DR, Ittmann M, Buxbaum JN, Wieczorek R, Gorevic PD, Jacobson DR, Ittmann M, Buxbaum JN, Wieczorek R, Gorevic PD. Transthyretin Ile 122 and cardiac amyloidosis in African-Americans. 2 case reports. Tex Heart Inst J. 1997; 24(1):45-52. PMID: 9068139; PMCID: PMC325397.
      Citations: 7     Fields:    Translation:Humans
    248. Ittman M, Mansukhani A, Ittman M, Mansukhani A. Expression of fibroblast growth factors (FGFs) and FGF receptors in human prostate. J Urol. 1997 Jan; 157(1):351-6. PMID: 8976296.
      Citations: 17     Fields:    Translation:Humans
    249. Ittmann M, Ittmann M. Allelic loss on chromosome 10 in prostate adenocarcinoma. Cancer Res. 1996 May 01; 56(9):2143-7. PMID: 8616863.
      Citations: 21     Fields:    Translation:HumansCells
    250. Ittmann MM, Ittmann MM. Loss of heterozygosity on chromosomes 10 and 17 in clinically localized prostate carcinoma. Prostate. 1996 May; 28(5):275-81. PMID: 8610052.
      Citations: 7     Fields:    Translation:HumansCells
    251. Ittmann MM, Wieczorek R, Ittmann MM, Wieczorek R. Alterations of the retinoblastoma gene in clinically localized, stage B prostate adenocarcinomas. Hum Pathol. 1996 Jan; 27(1):28-34. PMID: 8543307.
      Citations: 15     Fields:    Translation:HumansCells
    252. Jackson AJ, Ittmann M, Pugh BF, Jackson AJ, Ittmann M, Pugh BF. The BN51 protein is a polymerase (Pol)-specific subunit of RNA Pol III which reveals a link between Pol III transcription and pre-rRNA processing. Mol Cell Biol. 1995 Jan; 15(1):94-101. PMID: 7799973; PMCID: PMC231913.
      Citations: 5     Fields:    Translation:HumansCells
    253. Ittmann M, Wieczorek R, Heller P, Dave A, Provet J, Krolewski J, Ittmann M, Wieczorek R, Heller P, Dave A, Provet J, Krolewski J. Alterations in the p53 and MDM-2 genes are infrequent in clinically localized, stage B prostate adenocarcinomas. Am J Pathol. 1994 Aug; 145(2):287-93. PMID: 8053489; PMCID: PMC1887392.
      Citations: 11     Fields:    Translation:HumansCells
    254. Ittmann MM, Ittmann MM. Cell cycle control of the BN51 cell cycle gene which encodes a subunit of RNA polymerase III. Cell Growth Differ. 1994 Jul; 5(7):783-8. PMID: 7947392.
      Citations: 10     Fields:    Translation:AnimalsCells
    255. Ittmann M, Ali J, Greco A, Basilico C, Ittmann M, Ali J, Greco A, Basilico C. The gene complementing a temperature-sensitive cell cycle mutant of BHK cells is the human homologue of the yeast RPC53 gene, which encodes a subunit of RNA polymerase C (III). Cell Growth Differ. 1993 Jun; 4(6):503-11. PMID: 8373734.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    256. Law KF, Aranda CP, Smith RL, Berkowitz KA, Ittman MM, Lewis ML, Law KF, Aranda CP, Smith RL, Berkowitz KA, Ittman MM, Lewis ML. Pulmonary cryptococcosis mimicking methotrexate pneumonitis. J Rheumatol. 1993 May; 20(5):872-3. PMID: 8336316.
      Citations:    Fields:    Translation:HumansAnimals
    257. Talarico D, Ittmann MM, Bronson R, Basilico C, Talarico D, Ittmann MM, Bronson R, Basilico C. A retrovirus carrying the K-fgf oncogene induces diffuse meningeal tumors and soft-tissue fibrosarcomas. Mol Cell Biol. 1993 Apr; 13(4):1998-2010. PMID: 8455594; PMCID: PMC359521.
      Citations: 3     Fields:    Translation:AnimalsCells
    258. Watkins KV, Ittman MM, Watkins KV, Ittman MM. Necrotizing vasculitis in a patient with acquired immunodeficiency syndrome. J Oral Maxillofac Surg. 1992 Sep; 50(9):1000-3. PMID: 1506958.
      Citations:    Fields:    Translation:Humans
    259. Talarico D, Ittmann M, Balsari A, Delli-Bovi P, Basch RS, Basilico C, Talarico D, Ittmann M, Balsari A, Delli-Bovi P, Basch RS, Basilico C. Protection of mice against tumor growth by immunization with an oncogene-encoded growth factor. Proc Natl Acad Sci U S A. 1990 Jun; 87(11):4222-5. PMID: 2190216; PMCID: PMC54080.
      Citations: 3     Fields:    Translation:Animals
    260. Greco A, Gong SS, Ittmann M, Basilico C, Greco A, Gong SS, Ittmann M, Basilico C. Organization and expression of the cell cycle gene, ts11, that encodes asparagine synthetase. Mol Cell Biol. 1989 Jun; 9(6):2350-9. PMID: 2569668; PMCID: PMC362308.
      Citations: 20     Fields:    Translation:HumansCells
    261. Greco A, Ittmann M, Barletta C, Basilico C, Croce CM, Cannizzaro LA, Huebner K, Greco A, Ittmann M, Barletta C, Basilico C, Croce CM, Cannizzaro LA, Huebner K. Chromosomal localization of human genes required for G1 progression in mammalian cells. Genomics. 1989 Apr; 4(3):240-5. PMID: 2714790.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    262. Ittmann M, Greco A, Basilico C, Ittmann M, Greco A, Basilico C. Isolation of the human gene that complements a temperature-sensitive cell cycle mutation in BHK cells. Mol Cell Biol. 1987 Oct; 7(10):3386-93. PMID: 3683386; PMCID: PMC367988.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    263. Delli Bovi P, Curatola AM, Kern FG, Greco A, Ittmann M, Basilico C, Delli Bovi P, Curatola AM, Kern FG, Greco A, Ittmann M, Basilico C. An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family. Cell. 1987 Aug 28; 50(5):729-37. PMID: 2957062.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    264. Greco A, Ittmann M, Basilico C, Greco A, Ittmann M, Basilico C. Molecular cloning of a gene that is necessary for G1 progression in mammalian cells. Proc Natl Acad Sci U S A. 1987 Mar; 84(6):1565-9. PMID: 3470743; PMCID: PMC304476.
      Citations: 20     Fields:    Translation:HumansCells
    265. Feiner HD, Goldstein S, Ittman M, Pelton K, Jacobs J, Feiner HD, Goldstein S, Ittman M, Pelton K, Jacobs J. Oncocytic adenoma of the parotid gland with psammoma bodies. Arch Pathol Lab Med. 1986 Jul; 110(7):640-4. PMID: 3755026.
      Citations: 1     Fields:    Translation:HumansCells
    266. Ittmann MM, Cooper C, Ittmann MM, Cooper C. Heterogeneity of very-low-density lipoprotein remnants bound and taken up by liver of starved rat in vivo. Biochem J. 1983 Apr 15; 212(1):173-82. PMID: 6870849; PMCID: PMC1152026.
      Citations:    Fields:    Translation:AnimalsCells
    267. Ittmann MM, Cooper C, Ittmann MM, Cooper C. Endocytosis of very low density lipoprotein remnants by liver of fasted rats. J Biol Chem. 1982 Oct 25; 257(20):11953-9. PMID: 7118920.
      Citations: 2     Fields:    Translation:AnimalsCells
    268. Thomas LK, Ittmann M, Cooper C, Thomas LK, Ittmann M, Cooper C. The role of leucine in ketogenesis in starved rats. Biochem J. 1982 May 15; 204(2):399-403. PMID: 7115336; PMCID: PMC1158365.
      Citations: 15     Fields:    Translation:Animals
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