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Susan M. Rosenberg

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Human Genetics
DivisionMolecular & Human Genetics
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Biochemistry & Molecular Biology
    DivisionBiochemistry & Molecular Biology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular Virology & Microbiology
    DivisionMolecular Virology & Microbiology


    Collapse Affiliation 
    Collapse groups

    Collapse ORNG Applications 
    Collapse Faculty Mentor
    Collapse Verify Publications

    Collapse Biography 
    Collapse awards and honors
    1976 - 1980New York State Regents Scholarship Awards
    1977 - 1980US Basic Educational Opportunity Grant
    1980SUNY Potsdam Departmental Scholarship Award in Biology, The State University of New York
    1983 - 1986NIH Genetics Training Grant
    1987Association pour le Recherches sur le Cancer Visiting Scientist, Association pour le Recherches sur le Cancer
    1987American Cancer Society Postdoctoral Fellowship - declined
    1988 - 1991NIH Postdoctoral Fellowship
    1989National Research Council Guest Investigator Fellowship - declined, National Research Council (USA)
    1990Association pour le Recherches sur le Cancer Visiting Scientist, Association pour le Recherches sur le Cancer
    1991Alberta Heritage Foundation for Medical Research Postdoctoral Fellowship, Alberta Heritage Foundation for Medical Research
    1991National Cancer Institute Visiting Scientist Fellowship, National Cancer Institute
    1992 - 1995Alberta Heritage Foundation for Medical Research Establishment Grant, Alberta Heritage Foundation for Medical Research
    1992 - 1997Alberta Heritage Foundation for Medical Research Scholar, Salary Award, Alberta Heritage Foundation for Medical Research
    1995The Eli Lilly/National Cancer Institute of Canada William E. Rawls Prize (cancer research), The Eli Lilly/National Cancer Institute of Canada
    1996The Young Scientist Award of the Genetics Society of Canada
    1997 - 2002Alberta Heritage Foundation for Medical Research Scientist - declined, Alberta Heritage Foundation for Medical Research
    1999University of North Carolina, The Philip J. Bassford Memorial Lecture, Department of Microbiology and Immunology, University of North Carolina, Chapel Hill
    2000Baylor College of Medicine 8-Standed ß-Barrel Jelly Roll Award for Graduate Teaching Excellence, Baylor College of Medicine
    2001Baylor College of Medicine 8-Standed ß-Barrel Jelly Roll Award for Graduate Teaching Excellence, Baylor College of Medicine
    2001Michael E. DeBakey, M.D., Excellence in Research Award, Baylor College of Medicine
    2002American Society for Microbiology Division X Lecturer and award, American Society for Microbiology
    2002 - 2010The Cullen Foundation Endowed Professorship in Molecular Genetics, Baylor College of Medicine
    2006Baylor College of Medicine 8-Standed ß-Barrel Jelly Roll Award to Course Director, Best Course 2005, Baylor College of Medicine
    2008Baylor College of Medicine 8-Standed ß-Barrel Jelly Roll Award for, Best Lecturer, Baylor College of Medicine
    2009Honorary Lecture: Blaffer Lecture, MD Anderson Cancer Center
    2009NIH Director's Pioneer Award, National Institutes of Health
    2010Institute for Genomic Biology, University of Illinois Honorary Lecture: Pioneers in Genomics, Institute for Genomic Biology, University of Illinois, Urbana
    2010 - 2020Ben F. Love Chair in Cancer Research, Baylor College of Medicine
    2010Biosphere and Humanity Medal, Russian Academy of Medical Sciences, The Russian Scientific Society and Russian Academy of Medical Sciences
    2010Fellow, American Association for the Advancement of Science (elected), AAAS
    2013Fellow, American Academy of Microbiology (elected)
    2012 - 2014American Society for Microbiology Distinguished Lecturer, American Society for Microbiology
    2013President's Seminar Memorial Sloan Kettering Cancer Center
    2013National Institutes of Health Director's Seminar, National Institutes of Health

    Collapse Overview 
    Collapse overview
    Selected Other Service:
    2013-present, SCIENCE Senior Editorial Board
    2013-present, Leader, Cancer Evolvability Program, Dan L Duncan Cancer Center
    2011-2014, PLoS Biology Editorial Board
    2011-2013, Founder, Gordon Research Conference on Molecular Mechanisms in Evolution, 1st Chair
    2009-present, Faculty of 1000 Biology Reports Genetics and Genomics Advisory
    2008-present, Member Dan L Duncan Cancer Center, Baylor College of Medicine
    2007 Organizer, Current Trends Biomedicine Workshop: Stress, Stress Responses and Mechanisms of Evolvability, Baeza, Spain
    2005-present, PLoS Genetics Editorial Board
    2002-present, DNA Repair Editorial Board

    Collapse Research 
    Collapse research activities and funding
    F32GM012406     (ROSENBERG, SUSAN M.)Aug 14, 1988
    NIH/NIGMS
    HOMOLOGOUS RECOMBINATION IN X LAEVIS &E COLI
    Role: Principal Investigator

    R21GM053158     (ROSENBERG, SUSAN M.)Sep 30, 1995 - Aug 31, 1997
    NIH/NIGMS
    MOLECULAR MECHANISMS OF ADAPTIVE MUTATION IN E COLI
    Role: Principal Investigator

    R01GM053158     (ROSENBERG, SUSAN M.)Sep 30, 1995 - Jul 31, 2015
    NIH/NIGMS
    MOLECULAR MECHANISMS OF STRESS-INDUCED MUTATION IN E. COLI
    Role: Principal Investigator

    R01AI043917     (ROSENBERG, SUSAN M.)Jul 1, 1998 - May 31, 2004
    NIH/NIAID
    DNA REPAIR IN DRUG RESISTANCE MUTATION
    Role: Principal Investigator

    R01CA085777     (ROSENBERG, SUSAN M.)Oct 1, 1999 - Mar 31, 2014
    NIH/NCI
    DNA Repair and Replication Re-start in vivo
    Role: Principal Investigator

    R21ES014707     (ROSENBERG, SUSAN M.)Apr 6, 2006 - Feb 28, 2008
    NIH/NIEHS
    Molecular mechanism of DNA-polymerase choice in vivo
    Role: Principal Investigator

    DP1CA174424     (ROSENBERG, SUSAN M.)Sep 30, 2009 - Jul 31, 2014
    NIH/NCI
    Forward Genomics of Damage Control: An Undiscovered Class of Cancer Genes
    Role: Principal Investigator

    DP1OD006429     (ROSENBERG, SUSAN M.)Sep 30, 2009 - Jul 31, 2014
    NIH
    Forward Genomics of Damage Control: An Undiscovered Class of Cancer Genes
    Role: Principal Investigator

    R35GM122598     (ROSENBERG, SUSAN M.)Aug 1, 2017 - Jul 31, 2022
    NIH/NIGMS
    MOLECULAR MECHANISMS OF STRESS-INDUCED MUTATION
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Bossé Y, Li Z, Xia J, Manem V, Carreras-Torres R, Gabriel A, Gaudreault N, Albanes D, Aldrich MC, Andrew A, Arnold S, Bickeböller H, Bojesen SE, Brennan P, Brunnstrom H, Caporaso N, Chen C, Christiani DC, Field JK, Goodman G, Grankvist K, Houlston R, Johansson M, Johansson M, Kiemeney LA, Lam S, Landi MT, Lazarus P, Le Marchand L, Liu G, Melander O, Rennert G, Risch A, Rosenberg SM, Schabath MB, Shete S, Song Z, Stevens VL, Tardon A, Wichmann HE, Woll P, Zienolddiny S, Obeidat M, Timens W, Hung RJ, Joubert P, Amos CI, McKay JD. Transcriptome-wide association study reveals candidate causal genes for lung cancer. Int J Cancer. 2019 Nov 06. PMID: 31696517.
      View in: PubMed
    2. Xia J, Mei Q, Rosenberg SM. Tools To Live By: Bacterial DNA Structures Illuminate Cancer. Trends Genet. 2019 May; 35(5):383-395. PMID: 30962000.
      View in: PubMed
    3. Pribis JP, García-Villada L, Zhai Y, Lewin-Epstein O, Wang AZ, Liu J, Xia J, Mei Q, Fitzgerald DM, Bos J, Austin RH, Herman C, Bates D, Hadany L, Hastings PJ, Rosenberg SM. Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response. Mol Cell. 2019 05 16; 74(4):785-800.e7. PMID: 30948267.
      View in: PubMed
    4. Fitzgerald DM, Rosenberg SM. What is mutation? A chapter in the series: How microbes "jeopardize" the modern synthesis. PLoS Genet. 2019 04; 15(4):e1007995. PMID: 30933985.
      View in: PubMed
    5. Xia J, Chiu LY, Nehring RB, Bravo Núñez MA, Mei Q, Perez M, Zhai Y, Fitzgerald DM, Pribis JP, Wang Y, Hu CW, Powell RT, LaBonte SA, Jalali A, Matadamas Guzmán ML, Lentzsch AM, Szafran AT, Joshi MC, Richters M, Gibson JL, Frisch RL, Hastings PJ, Bates D, Queitsch C, Hilsenbeck SG, Coarfa C, Hu JC, Siegele DA, Scott KL, Liang H, Mancini MA, Herman C, Miller KM, Rosenberg SM. Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. Cell. 2019 01 10; 176(1-2):127-143.e24. PMID: 30633903.
      View in: PubMed
    6. Klein HL, Bacinskaja G, Che J, Cheblal A, Elango R, Epshtein A, Fitzgerald DM, Gómez-González B, Khan SR, Kumar S, Leland BA, Marie L, Mei Q, Miné-Hattab J, Piotrowska A, Polleys EJ, Putnam CD, Radchenko EA, Saada AA, Sakofsky CJ, Shim EY, Stracy M, Xia J, Yan Z, Yin Y, Aguilera A, Argueso JL, Freudenreich CH, Gasser SM, Gordenin DA, Haber JE, Ira G, Jinks-Robertson S, King MC, Kolodner RD, Kuzminov A, Lambert SA, Lee SE, Miller KM, Mirkin SM, Petes TD, Rosenberg SM, Rothstein R, Symington LS, Zawadzki P, Kim N, Lisby M, Malkova A. Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microb Cell. 2019 Jan 07; 6(1):1-64. PMID: 30652105.
      View in: PubMed
    7. Kotlajich MV, Xia J, Zhai Y, Lin HY, Bradley CC, Shen X, Mei Q, Wang AZ, Lynn EJ, Shee C, Chen LT, Li L, Miller KM, Herman C, Hastings PJ, Rosenberg SM. Fluorescent fusions of the N protein of phage Mu label DNA damage in living cells. DNA Repair (Amst). 2018 12; 72:86-92. PMID: 30268364.
      View in: PubMed
    8. Correa R, Thornton PC, Rosenberg SM, Hastings PJ. Oxygen and RNA in stress-induced mutation. Curr Genet. 2018 Aug; 64(4):769-776. PMID: 29294174.
      View in: PubMed
    9. Hastings PJ, Rosenberg SM. A radical way to die. Nat Microbiol. 2017 12; 2(12):1582-1583. PMID: 29176695.
      View in: PubMed
    10. Sivaramakrishnan P, Sepúlveda LA, Halliday JA, Liu J, Núñez MAB, Golding I, Rosenberg SM, Herman C. The transcription fidelity factor GreA impedes DNA break repair. Nature. 2017 10 12; 550(7675):214-218. PMID: 28976965.
      View in: PubMed
    11. Moore JM, Correa R, Rosenberg SM, Hastings PJ. Persistent damaged bases in DNA allow mutagenic break repair in Escherichia coli. PLoS Genet. 2017 Jul; 13(7):e1006733. PMID: 28727736.
      View in: PubMed
    12. Fitzgerald DM, Rosenberg SM. Driving cancer evolution. Elife. 2017 03 10; 6. PMID: 28282287.
      View in: PubMed
    13. Fitzgerald DM, Hastings PJ, Rosenberg SM. Stress-Induced Mutagenesis: Implications in Cancer and Drug Resistance. Annu Rev Cancer Biol. 2017 Mar; 1:119-140. PMID: 29399660.
      View in: PubMed
    14. Barreto B, Rogers E, Xia J, Frisch RL, Richters M, Fitzgerald DM, Rosenberg SM. The Small RNA GcvB Promotes Mutagenic Break Repair by Opposing the Membrane Stress Response. J Bacteriol. 2016 12 15; 198(24):3296-3308. PMID: 27698081.
      View in: PubMed
    15. Xia J, Chen LT, Mei Q, Ma CH, Halliday JA, Lin HY, Magnan D, Pribis JP, Fitzgerald DM, Hamilton HM, Richters M, Nehring RB, Shen X, Li L, Bates D, Hastings PJ, Herman C, Jayaram M, Rosenberg SM. Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase. Sci Adv. 2016 Nov; 2(11):e1601605. PMID: 28090586.
      View in: PubMed
    16. Dohrmann PR, Correa R, Frisch RL, Rosenberg SM, McHenry CS. The DNA polymerase III holoenzyme contains ? and is not a trimeric polymerase. Nucleic Acids Res. 2016 Feb 18; 44(3):1285-97. PMID: 26786318.
      View in: PubMed
    17. Nehring RB, Gu F, Lin HY, Gibson JL, Blythe MJ, Wilson R, Bravo Núñez MA, Hastings PJ, Louis EJ, Frisch RL, Hu JC, Rosenberg SM. An ultra-dense library resource for rapid deconvolution of mutations that cause phenotypes in Escherichia coli. Nucleic Acids Res. 2016 Mar 18; 44(5):e41. PMID: 26578563.
      View in: PubMed
    18. Moore JM, Magnan D, Mojica AK, Núñez MA, Bates D, Rosenberg SM, Hastings PJ. Roles of Nucleoid-Associated Proteins in Stress-Induced Mutagenic Break Repair in Starving Escherichia coli. Genetics. 2015 Dec; 201(4):1349-62. PMID: 26500258.
      View in: PubMed
    19. Gibson JL, Lombardo MJ, Aponyi I, Vera Cruz D, Ray MP, Rosenberg SM. Atypical Role for PhoU in Mutagenic Break Repair under Stress in Escherichia coli. PLoS One. 2015; 10(5):e0123315. PMID: 25961709.
      View in: PubMed
    20. Bos J, Zhang Q, Vyawahare S, Rogers E, Rosenberg SM, Austin RH. Emergence of antibiotic resistance from multinucleated bacterial filaments. Proc Natl Acad Sci U S A. 2015 Jan 06; 112(1):178-83. PMID: 25492931.
      View in: PubMed
    21. Rosenberg SM, Queitsch C. Medicine. Combating evolution to fight disease. Science. 2014 Mar 07; 343(6175):1088-9. PMID: 24604189.
      View in: PubMed
    22. Shee C, Cox BD, Gu F, Luengas EM, Joshi MC, Chiu LY, Magnan D, Halliday JA, Frisch RL, Gibson JL, Nehring RB, Do HG, Hernandez M, Li L, Herman C, Hastings PJ, Bates D, Harris RS, Miller KM, Rosenberg SM. Engineered proteins detect spontaneous DNA breakage in human and bacterial cells. Elife. 2013 Oct 29; 2:e01222. PMID: 24171103.
      View in: PubMed
    23. Hamilton HM, Wilson R, Blythe M, Nehring RB, Fonville NC, Louis EJ, Rosenberg SM. Thymineless death is inhibited by CsrA in Escherichia coli lacking the SOS response. DNA Repair (Amst). 2013 Nov; 12(11):993-9. PMID: 24075571.
      View in: PubMed
    24. Walker SI, Callahan BJ, Arya G, Barry JD, Bhattacharya T, Grigoryev S, Pellegrini M, Rippe K, Rosenberg SM. Evolutionary dynamics and information hierarchies in biological systems. Ann N Y Acad Sci. 2013 Dec; 1305:1-17. PMID: 23691975.
      View in: PubMed
    25. Wimberly H, Shee C, Thornton PC, Sivaramakrishnan P, Rosenberg SM, Hastings PJ. R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli. Nat Commun. 2013; 4:2115. PMID: 23828459.
      View in: PubMed
    26. Rosenberg SM. Brenner's Encyclopedia of Genetics, S Malloy and K Hughes, Eds.,. Reverse Mutation. 2013; 6:220-221.
    27. Rosenberg SM, Hastings PJ. Brenner’s Encyclopedia of Genetics, S Malloy and K Hughes, Eds. Hfr. 2013; 3:459-461.
    28. Rosenberg SM, Hastings PJ. Brenner’s Encyclopedia of Genetics, S Malloy and K Hughes, Eds. rec Genes. 2013; 6:47-50.
    29. Rosenberg SM, Hastings PJ. Brenner’s Encyclopedia of Genetics, S Malloy and K Hughes, Eds. RuvAB enzyme. 2013; 6:307-309.
    30. Rosenberg SM, Hastings PJ. Brenner’s Encyclopedia of Genetics, S Malloy and K Hughes, Eds. RuvC enzyme. 2013; 6:310-311.
    31. Rosenberg SM, Hastings PJ. Brenner’s Encyclopedia of Genetics, S Malloy and K Hughes, Eds. Sexduction. 2013; 6:408.
    32. Shee C, Hastings PJ, Rosenberg SM. Stress-Induced Mutagenesis, D Mittelman, Ed. Mutagenesis associated with repair of DNA double-strand breaks under stress. 2013; 21-39.
    33. Al Mamun AA, Lombardo MJ, Shee C, Lisewski AM, Gonzalez C, Lin D, Nehring RB, Saint-Ruf C, Gibson JL, Frisch RL, Lichtarge O, Hastings PJ, Rosenberg SM. Identity and function of a large gene network underlying mutagenic repair of DNA breaks. Science. 2012 Dec 07; 338(6112):1344-8. PMID: 23224554.
      View in: PubMed
    34. Shee C, Gibson JL, Rosenberg SM. Two mechanisms produce mutation hotspots at DNA breaks in Escherichia coli. Cell Rep. 2012 Oct 25; 2(4):714-21. PMID: 23041320.
      View in: PubMed
    35. Moore JM, Wimberly H, Thornton PC, Rosenberg SM, Hastings PJ. Gross chromosomal rearrangement mediated by DNA replication in stressed cells: evidence from Escherichia coli. Ann N Y Acad Sci. 2012 Sep; 1267:103-9. PMID: 22954223.
      View in: PubMed
    36. Rosenberg SM, Shee C, Frisch RL, Hastings PJ. Stress-induced mutation via DNA breaks in Escherichia coli: a molecular mechanism with implications for evolution and medicine. Bioessays. 2012 Oct; 34(10):885-92. PMID: 22911060.
      View in: PubMed
    37. Shee C, Ponder R, Gibson JL, Rosenberg SM. What limits the efficiency of double-strand break-dependent stress-induced mutation in Escherichia coli? J Mol Microbiol Biotechnol. 2011; 21(1-2):8-19. PMID: 22248539.
      View in: PubMed
    38. Hastings PJ, Rosenberg SM. Genomic rearrangement in three dimensions. Nat Biotechnol. 2011 Dec 08; 29(12):1096-8. PMID: 22158363.
      View in: PubMed
    39. Frisch RL, Rosenberg SM. Microbiology. Antibiotic resistance, not shaken or stirred. Science. 2011 Sep 23; 333(6050):1713-4. PMID: 21940884.
      View in: PubMed
    40. Rosenberg SM. Stress-induced loss of heterozygosity in Candida: a possible missing link in the ability to evolve. MBio. 2011; 2(5). PMID: 21933916.
      View in: PubMed
    41. Shee C, Gibson JL, Darrow MC, Gonzalez C, Rosenberg SM. Impact of a stress-inducible switch to mutagenic repair of DNA breaks on mutation in Escherichia coli. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13659-64. PMID: 21808005.
      View in: PubMed
    42. Fonville NC, Vaksman Z, DeNapoli J, Hastings PJ, Rosenberg SM. Pathways of resistance to thymineless death in Escherichia coli and the function of UvrD. Genetics. 2011 Sep; 189(1):23-36. PMID: 21705756.
      View in: PubMed
    43. Rosenberg SM. Spontaneous mutation: real-time in living cells. Curr Biol. 2010 Sep 28; 20(18):R810-1. PMID: 20869609.
      View in: PubMed
    44. Frisch RL, Su Y, Thornton PC, Gibson JL, Rosenberg SM, Hastings PJ. Separate DNA Pol II- and Pol IV-dependent pathways of stress-induced mutation during double-strand-break repair in Escherichia coli are controlled by RpoS. J Bacteriol. 2010 Sep; 192(18):4694-700. PMID: 20639336.
      View in: PubMed
    45. Hastings PJ, Hersh MN, Thornton PC, Fonville NC, Slack A, Frisch RL, Ray MP, Harris RS, Leal SM, Rosenberg SM. Competition of Escherichia coli DNA polymerases I, II and III with DNA Pol IV in stressed cells. PLoS One. 2010 May 27; 5(5):e10862. PMID: 20523737.
      View in: PubMed
    46. Gibson JL, Lombardo MJ, Thornton PC, Hu KH, Galhardo RS, Beadle B, Habib A, Magner DB, Frost LS, Herman C, Hastings PJ, Rosenberg SM. The sigma(E) stress response is required for stress-induced mutation and amplification in Escherichia coli. Mol Microbiol. 2010 Jul; 77(2):415-30. PMID: 20497332.
      View in: PubMed
    47. Fonville NC, Bates D, Hastings PJ, Hanawalt PC, Rosenberg SM. Role of RecA and the SOS response in thymineless death in Escherichia coli. PLoS Genet. 2010 Mar 05; 6(3):e1000865. PMID: 20221259.
      View in: PubMed
    48. Fonville NC, Blankschien MD, Magner DB, Rosenberg SM. RecQ-dependent death-by-recombination in cells lacking RecG and UvrD. DNA Repair (Amst). 2010 Apr 04; 9(4):403-13. PMID: 20138014.
      View in: PubMed
    49. Singletary LA, Gibson JL, Tanner EJ, McKenzie GJ, Lee PL, Gonzalez C, Rosenberg SM. An SOS-regulated type 2 toxin-antitoxin system. J Bacteriol. 2009 Dec; 191(24):7456-65. PMID: 19837801.
      View in: PubMed
    50. Hastings PJ, Lupski JR, Rosenberg SM, Ira G. Mechanisms of change in gene copy number. Nat Rev Genet. 2009 Aug; 10(8):551-64. PMID: 19597530.
      View in: PubMed
    51. Petrosino JF, Galhardo RS, Morales LD, Rosenberg SM. Stress-induced beta-lactam antibiotic resistance mutation and sequences of stationary-phase mutations in the Escherichia coli chromosome. J Bacteriol. 2009 Oct; 191(19):5881-9. PMID: 19648247.
      View in: PubMed
    52. Galhardo RS, Rosenberg SM. Extreme genome repair. Cell. 2009 Mar 20; 136(6):998-1000. PMID: 19303843.
      View in: PubMed
    53. Rosenberg SM. Life, death, differentiation, and the multicellularity of bacteria. PLoS Genet. 2009 Mar; 5(3):e1000418. PMID: 19282973.
      View in: PubMed
    54. Galhardo RS, Do R, Yamada M, Friedberg EC, Hastings PJ, Nohmi T, Rosenberg SM. DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli. Genetics. 2009 May; 182(1):55-68. PMID: 19270270.
      View in: PubMed
    55. Gonzalez C, Hadany L, Ponder RG, Price M, Hastings PJ, Rosenberg SM. Mutability and importance of a hypermutable cell subpopulation that produces stress-induced mutants in Escherichia coli. PLoS Genet. 2008 Oct 03; 4(10):e1000208. PMID: 18833303.
      View in: PubMed
    56. Gumbiner-Russo LM, Rosenberg SM. Physical analyses of E. coli heteroduplex recombination products in vivo: on the prevalence of 5' and 3' patches. PLoS One. 2007 Nov 28; 2(11):e1242. PMID: 18043749.
      View in: PubMed
    57. Galhardo RS, Hastings PJ, Rosenberg SM. Mutation as a stress response and the regulation of evolvability. Crit Rev Biochem Mol Biol. 2007 Sep-Oct; 42(5):399-435. PMID: 17917874.
      View in: PubMed
    58. Pennington JM, Rosenberg SM. Spontaneous DNA breakage in single living Escherichia coli cells. Nat Genet. 2007 Jun; 39(6):797-802. PMID: 17529976.
      View in: PubMed
    59. Magner DB, Blankschien MD, Lee JA, Pennington JM, Lupski JR, Rosenberg SM. RecQ promotes toxic recombination in cells lacking recombination intermediate-removal proteins. Mol Cell. 2007 Apr 27; 26(2):273-86. PMID: 17466628.
      View in: PubMed
    60. Katsanis N, Rosenberg SM. An age-old problem. PLoS Genet. 2007 Feb 23; 3(2):e37. PMID: 17319751.
      View in: PubMed
    61. Rosenberg SM, Cox MM. Introduction (Introductory editorial to series "Mechanisms of Evolution"). Crit Rev Biochem Mol Biol. 2007; (42):245.
    62. Slack A, Thornton PC, Magner DB, Rosenberg SM, Hastings PJ. On the mechanism of gene amplification induced under stress in Escherichia coli. PLoS Genet. 2006 Apr; 2(4):e48. PMID: 16604155.
      View in: PubMed
    63. Hersh MN, Morales LD, Ross KJ, Rosenberg SM. Single-strand-specific exonucleases prevent frameshift mutagenesis by suppressing SOS induction and the action of DinB/DNA polymerase IV in growing cells. J Bacteriol. 2006 Apr; 188(7):2336-42. PMID: 16547019.
      View in: PubMed
    64. He AS, Rohatgi PR, Hersh MN, Rosenberg SM. Roles of E. coli double-strand-break-repair proteins in stress-induced mutation. DNA Repair (Amst). 2006 Feb 03; 5(2):258-73. PMID: 16310415.
      View in: PubMed
    65. Lopez CR, Yang S, Deibler RW, Ray SA, Pennington JM, Digate RJ, Hastings PJ, Rosenberg SM, Zechiedrich EL. A role for topoisomerase III in a recombination pathway alternative to RuvABC. Mol Microbiol. 2005 Oct; 58(1):80-101. PMID: 16164551.
      View in: PubMed
    66. Ponder RG, Fonville NC, Rosenberg SM. A switch from high-fidelity to error-prone DNA double-strand break repair underlies stress-induced mutation. Mol Cell. 2005 Sep 16; 19(6):791-804. PMID: 16168374.
      View in: PubMed
    67. Hastings PJ, Slack A, Petrosino JF, Rosenberg SM. Adaptive amplification and point mutation are independent mechanisms: evidence for various stress-inducible mutation mechanisms. PLoS Biol. 2004 Dec; 2(12):e399. PMID: 15550983.
      View in: PubMed
    68. McCool JD, Long E, Petrosino JF, Sandler HA, Rosenberg SM, Sandler SJ. Measurement of SOS expression in individual Escherichia coli K-12 cells using fluorescence microscopy. Mol Microbiol. 2004 Sep; 53(5):1343-57. PMID: 15387814.
      View in: PubMed
    69. Hastings PJ, Rosenberg SM, Slack A. Antibiotic-induced lateral transfer of antibiotic resistance. Trends Microbiol. 2004 Sep; 12(9):401-4. PMID: 15337159.
      View in: PubMed
    70. Rosenberg SM, Hastings PJ. Genomes: worming into genetic instability. Nature. 2004 Aug 05; 430(7000):625-6. PMID: 15295584.
      View in: PubMed
    71. Rosenberg SM, Hastings PJ. Rebuttal: adaptive mutation in Escherichia coli (Foster). J Bacteriol. 2004 Aug; 186(15):4853. PMID: 15262918.
      View in: PubMed
    72. Rosenberg SM, Hastings PJ. Rebuttal: growth under selection stimulates Lac(+) reversion (Roth and Andersson). J Bacteriol. 2004 Aug; 186(15):4862-3. PMID: 15262922.
      View in: PubMed
    73. Rosenberg SM, Hastings PJ. Adaptive point mutation and adaptive amplification pathways in the Escherichia coli Lac system: stress responses producing genetic change. J Bacteriol. 2004 Aug; 186(15):4838-43. PMID: 15262914.
      View in: PubMed
    74. Hersh MN, Ponder RG, Hastings PJ, Rosenberg SM. Adaptive mutation and amplification in Escherichia coli: two pathways of genome adaptation under stress. Res Microbiol. 2004 Jun; 155(5):352-9. PMID: 15207867.
      View in: PubMed
    75. Lombardo MJ, Aponyi I, Rosenberg SM. General stress response regulator RpoS in adaptive mutation and amplification in Escherichia coli. Genetics. 2004 Feb; 166(2):669-80. PMID: 15020458.
      View in: PubMed
    76. Lombardo MJ, Aponyi I, Ray MP, Sandigursky M, Franklin WA, Rosenberg SM. xni-deficient Escherichia coli are proficient for recombination and multiple pathways of repair. DNA Repair (Amst). 2003 Nov 21; 2(11):1175-83. PMID: 14599740.
      View in: PubMed
    77. McKenzie GJ, Magner DB, Lee PL, Rosenberg SM. The dinB operon and spontaneous mutation in Escherichia coli. J Bacteriol. 2003 Jul; 185(13):3972-7. PMID: 12813093.
      View in: PubMed
    78. Rosenberg SM, Hastings PJ. Microbiology and evolution. Modulating mutation rates in the wild. Science. 2003 May 30; 300(5624):1382-3. PMID: 12775830.
      View in: PubMed
    79. Chi X, Zhang SX, Yu W, DeMayo FJ, Rosenberg SM, Schwartz RJ. Expression of Nkx2-5-GFP bacterial artificial chromosome transgenic mice closely resembles endogenous Nkx2-5 gene activity. Genesis. 2003 Apr; 35(4):220-6. PMID: 12717733.
      View in: PubMed
    80. Petrosino JF, Pendleton AR, Weiner JH, Rosenberg SM. Chromosomal system for studying AmpC-mediated beta-lactam resistance mutation in Escherichia coli. Antimicrob Agents Chemother. 2002 May; 46(5):1535-9. PMID: 11959593.
      View in: PubMed
    81. Hastings PJ, Rosenberg SM. In pursuit of a molecular mechanism for adaptive gene amplification. DNA Repair (Amst). 2002 Feb 28; 1(2):111-23. PMID: 12509258.
      View in: PubMed
    82. Rosenberg SM. Mutation. McGraw-Hill Yearbook of Science and Technology. 2002; 232-4.
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    100. Lombardo MJ, Rosenberg SM. radC102 of Escherichia coli is an allele of recG. J Bacteriol. 2000 Nov; 182(22):6287-91. PMID: 11053371.
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    101. McKenzie GJ, Harris RS, Lee PL, Rosenberg SM. The SOS response regulates adaptive mutation. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6646-51. PMID: 10829077.
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    102. Bull HJ, McKenzie GJ, Hastings PJ, Rosenberg SM. Evidence that stationary-phase hypermutation in the Escherichia coli chromosome is promoted by recombination. Genetics. 2000 Apr; 154(4):1427-37. PMID: 10747042.
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    103. Bull HJ, McKenzie GJ, Hastings PJ, Rosenberg SM. The contribution of transiently hypermutable cells to mutation in stationary phase. Gentics. 2000; (156):925-26.
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    105. Harris RS, Feng G, Ross KJ, Sidhu R, Thulin C, Longerich S, Szigety SK, Hastings PJ, Winkler ME, Rosenberg SM. Mismatch repair is diminished during stationary-phase mutation. Mutat Res. 1999 Jul; 437(1):51-60. PMID: 10425389.
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    109. Lombardo M-J, Harris RS, Rosenberg SM. Stressful lifestyle-associated mutation in microorganisms. In Lerner HR (Ed) Plant Responses to Environmental Stress, From Phytohormones to Gene Reorganization, Dekker M, New York. 1999; 71-90.
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    111. Rosenberg SM. News we can use from bacterial chromosomes. Trends Genet. 1998 May; 14(5):175-6. PMID: 9613200.
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    112. Rosenberg SM, Thulin C, Harris RS. Transient and heritable mutators in adaptive evolution in the lab and in nature. Genetics. 1998 Apr; 148(4):1559-66. PMID: 9560375.
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    113. Harris RS, Ross KJ, Lombardo MJ, Rosenberg SM. Mismatch repair in Escherichia coli cells lacking single-strand exonucleases ExoI, ExoVII, and RecJ. J Bacteriol. 1998 Feb; 180(4):989-93. PMID: 9473057.
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    115. Rosenberg SM. Mutation for survival. Curr Opin Genet Dev. 1997 Dec; 7(6):829-34. PMID: 9468794.
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    117. Torkelson J, Harris RS, Lombardo MJ, Nagendran J, Thulin C, Rosenberg SM. Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation. EMBO J. 1997 Jun 02; 16(11):3303-11. PMID: 9214645.
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    118. Harris RS, Bull HJ, Rosenberg SM. A direct role for DNA polymerase III in adaptive reversion of a frameshift mutation in Escherichia coli. Mutat Res. 1997 Apr 14; 375(1):19-24. PMID: 9129676.
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    119. Harris RS, Ross KJ, Rosenberg SM. Opposing roles of the holliday junction processing systems of Escherichia coli in recombination-dependent adaptive mutation. Genetics. 1996 Mar; 142(3):681-91. PMID: 8849879.
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    120. Rosenberg SM, Harris RS, Longerich S, Galloway AM. Recombination-dependent mutation in non-dividing cells. Mutat Res. 1996 Feb 19; 350(1):69-76. PMID: 8657199.
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    121. Manivasakam P, Rosenberg SM, Hastings PJ. Poorly repaired mismatches in heteroduplex DNA are hyper-recombinagenic in Saccharomyces cerevisiae. Genetics. 1996 Feb; 142(2):407-16. PMID: 8852840.
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    122. Razavy H, Szigety SK, Rosenberg SM. Evidence for both 3' and 5' single-strand DNA ends in intermediates in chi-stimulated recombination in vivo. Genetics. 1996 Feb; 142(2):333-9. PMID: 8852834.
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    123. Longerich S, Galloway AM, Harris RS, Wong C, Rosenberg SM. Adaptive mutation sequences reproduced by mismatch repair deficiency. Proc Natl Acad Sci U S A. 1995 Dec 19; 92(26):12017-20. PMID: 8618835.
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    124. Rosenberg SM, Harris RS, Torkelson J. Molecular handles on adaptive mutation. Mol Microbiol. 1995 Oct; 18(2):185-9. PMID: 8709838.
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    125. Rosenberg SM. In pursuit of a molecular mechanism for adaptive mutation. Genome. 1994 Dec; 37(6):893-9. PMID: 7828837.
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    126. Rosenberg SM, Longerich S, Gee P, Harris RS. Adaptive mutation by deletions in small mononucleotide repeats. Science. 1994 Jul 15; 265(5170):405-7. PMID: 8023163.
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    129. Hagemann AT, Rosenberg SM. Chain bias in Chi-stimulated heteroduplex patches in the lambda ren gene is determined by the orientation of lambda cos. Genetics. 1991 Nov; 129(3):611-21. PMID: 1836442.
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    130. Rosenberg SM, Hastings PJ. The split-end model for homologous recombination at double-strand breaks and at Chi. Biochimie. 1991 Apr; 73(4):385-97. PMID: 1911939.
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    131. Rosenberg SM. Preparation of packaging extracts from one lysogen: packaging of bacteriophage lamda DNA in vitro using one extract. In Molecular Cloning, A Laboratory Manual, Second Edition, compiled by Sambrook J, Fritsch EF, Maniatis T. Cold Spring Harbor Laboraroty Press, Cold Spring Harbor, New York. 1989; 2.105-2.107.
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    133. Rosenberg SM. Chain-bias of Escherichia coli Rec-mediated lambda patch recombinants is independent of the orientation of lambda cos. Genetics. 1988 Sep; 120(1):7-21. PMID: 2975616.
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    134. Thaler DS, Sampson E, Siddiqi I, Rosenberg SM, Sampson B. A hypothesis: Chi-activation of RecBCD enzyme involves removal of the RecD subunit. In Friedberg EC, Hanawalt PC (Eds) Mechanisms and Consequences of DNA Damage Processing Alan R. Liss. 1988; 413-22.
    135. Rosenberg SM. Chi-stimulated patches are heteroduplex, with recombinant information on the phage lambda r chain. Cell. 1987 Mar 13; 48(5):855-65. PMID: 2949853.
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    136. Stahl FW, Thaler DS, Kolodkin A, Rosenberg SM, Sampson B. Double chain breaks: thinking about them in phage and fungi. In Alacevic M (Ed), Genetics of Industrial Microoganisms, Proceedings of the Fifth International Symposium on the Genetics of Industrial Microorganisms (Zagreb Yugoslavia). 1987; 13-6.
    137. Rosenberg SM. Improved in vitro packaging of lambda DNA. PMID: 2963201. Methods in Enzymology. 1987; 153:95-103.
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    140. Rosenberg SM, Stahl MM, Kobayashi I, Stahl FW. Improved in vitro packaging of coliphage lambda DNA: a one-strain system free from endogenous phage. Gene. 1985; 38(1-3):165-75. PMID: 2933300.
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    141. Rosenberg SM. EcoK restriction during in vitro packaging of coliphage lambda DNA. Gene. 1985; 39(2-3):313-5. PMID: 3005116.
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    142. Rosenberg SM, Bonnett HT. Floral organogenesis in Nicotiana tabacum: a comparison of two cytoplasmic male-sterile cultivars with a male-fertile cultivar. Amer. J. Botany. 1983; (70):266-75.
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