DOROTHY LEWIS

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
AddressOne Baylor Plaza
Houston, TX 77030
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    R33AI116208     (LEWIS, DOROTHY E.)Sep 1, 2014 - Aug 31, 2019
    NIH
    Adipose Tissue is a significant reservoir for HIV
    Role: Principal Investigator

    R21AI116208     (LEWIS, DOROTHY E.)Sep 1, 2014 - Aug 31, 2016
    NIH
    Adipose Tissue is a significant reservoir for HIV
    Role: Principal Investigator

    R01HD046623     (LEWIS, DOROTHY E)Dec 1, 2004 - Nov 30, 2009
    NIH
    Molecular Nature of Fetal DNA in Maternal Plasma
    Role: Principal Investigator

    R21AI054251     (LEWIS, DOROTHY E)Aug 15, 2003 - Jul 31, 2006
    NIH
    Formation and Function of Human CD28-Negative T Cells
    Role: Principal Investigator

    S10RR011909     (LEWIS, DOROTHY E)Jun 1, 1997 - May 31, 1998
    NIH
    FLOW CYTOMETER FOR MOLECULAR MEDICINE AND HIV RESEARCH
    Role: Principal Investigator

    R37AI036682     (LEWIS, DOROTHY E.)Jul 1, 1995 - Mar 31, 2012
    NIH
    ANERGY, APOPTOSIS AND CD28 IN CD8+ T CELLS DURING AIDS
    Role: Principal Investigator

    R01AI036682     (LEWIS, DOROTHY E)Jul 1, 1995 - Jun 30, 2000
    NIH
    ANERGY, APOPTOSIS AND CD28 IN CD8+ T CELLS DURING AIDS
    Role: Principal Investigator

    S10RR003980     (LEWIS, DOROTHY E)May 16, 1988 - May 15, 1989
    NIH
    PURCHASE OF A FLOW CYTOMETER
    Role: Principal Investigator

    R01AI022549     (LEWIS, DOROTHY E)Jul 1, 1985 - Aug 31, 1992
    NIH
    IMMUNOREGULATION IN ASYMPTOMATIC HIV-INFECTED PEOPLE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Skaug B, Guo X, Li YJ, Charles J, Pham KT, Couturier J, Lewis DE, Bracaglia C, Caiello I, Mayes MD, Assassi S. Reduced digestion of circulating genomic DNA in systemic sclerosis patients with the DNASE1L3 R206C variant. Rheumatology (Oxford). 2023 09 01; 62(9):3197-3204. PMID: 36708011; PMCID: PMC10473277.
      Citations:    Fields:    
    2. Pons-Faudoa FP, Trani ND, Sizovs A, Shelton KA, Momin Z, Bushman LR, Xu J, Lewis DE, Demaria S, Hawkins T, Rooney JF, Marzinke MA, Kimata JT, Anderson PL, Nehete PN, Arduino RC, Sastry KJ, Grattoni A. Viral load Reduction in SHIV-Positive Nonhuman Primates via Long-Acting Subcutaneous Tenofovir Alafenamide Fumarate Release from a Nanofluidic Implant. Pharmaceutics. 2020 Oct 17; 12(10). PMID: 33080776; PMCID: PMC7590004.
      Citations: 6     
    3. Couturier J, Nuotio-Antar AM, Agarwal N, Wilkerson GK, Saha P, Kulkarni V, Lakhashe SK, Esquivel J, Nehete PN, Ruprecht RM, Sastry KJ, Meyer JM, Hill LR, Lake JE, Balasubramanyam A, Lewis DE. Lymphocytes upregulate CD36 in adipose tissue and liver. Adipocyte. 2019 12; 8(1):154-163. PMID: 31035848; PMCID: PMC6768236.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    4. Liu H, Hu PW, Budhiraja S, Misra A, Couturier J, Lloyd RE, Lewis DE, Kimata JT, Rice AP. PACS1 is an HIV-1 cofactor that functions in Rev-mediated nuclear export of viral RNA. Virology. 2020 01 15; 540:88-96. PMID: 31759187; PMCID: PMC7335006.
      Citations: 3     Fields:    Translation:HumansCells
    5. Lewis DE, Lysaght J, Wu H. Editorial: T Cell Alterations in Adipose Tissue During Obesity, HIV, and Cancer. Front Immunol. 2019; 10:1190. PMID: 31191549; PMCID: PMC6546799.
      Citations: 2     Fields:    Translation:HumansCells
    6. Couturier J, Orozco AF, Liu H, Budhiraja S, Siwak EB, Nehete PN, Sastry KJ, Rice AP, Lewis DE. Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells. Virol J. 2019 02 20; 16(1):22. PMID: 30786885; PMCID: PMC6381639.
      Citations: 6     Fields:    Translation:HumansCells
    7. Liu H, Hu PW, Couturier J, Lewis DE, Rice AP. HIV-1 replication in CD4+ T cells exploits the down-regulation of antiviral NEAT1 long non-coding RNAs following T cell activation. Virology. 2018 09; 522:193-198. PMID: 30036787; PMCID: PMC6136447.
      Citations: 12     Fields:    Translation:HumansCells
    8. Huang Y, Chen Z, Jang JH, Baig MS, Bertolet G, Schroeder C, Huang S, Hu Q, Zhao Y, Lewis DE, Qin L, Zhu MX, Liu D. PD-1 blocks lytic granule polarization with concomitant impairment of integrin outside-in signaling in the natural killer cell immunological synapse. J Allergy Clin Immunol. 2018 10; 142(4):1311-1321.e8. PMID: 29679656; PMCID: PMC6324560.
      Citations: 6     Fields:    Translation:HumansCells
    9. Couturier J, Winchester LC, Suliburk JW, Wilkerson GK, Podany AT, Agarwal N, Xuan Chua CY, Nehete PN, Nehete BP, Grattoni A, Sastry KJ, Fletcher CV, Lake JE, Balasubramanyam A, Lewis DE. Adipocytes impair efficacy of antiretroviral therapy. Antiviral Res. 2018 06; 154:140-148. PMID: 29630975; PMCID: PMC5955795.
      Citations: 17     Fields:    Translation:HumansCells
    10. Couturier J, Lewis DE. HIV Persistence in Adipose Tissue Reservoirs. Curr HIV/AIDS Rep. 2018 02; 15(1):60-71. PMID: 29423731; PMCID: PMC5876154.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    11. Zhao S, Adebiyi MG, Zhang Y, Couturier JP, Fan X, Zhang H, Kellems RE, Lewis DE, Xia Y. Sphingosine-1-phosphate receptor 1 mediates elevated IL-6 signaling to promote chronic inflammation and multitissue damage in sickle cell disease. FASEB J. 2018 05; 32(5):2855-2865. PMID: 29401601; PMCID: PMC5901384.
      Citations: 17     Fields:    Translation:AnimalsCells
    12. Fadul N, Couturier J, Yu X, Kozinetz C, Arduino R, Lewis DE. Treatment-Na?ve HIV-Infected Patients Have Fewer Gut-Homing ?7 Memory CD4 T Cells than Healthy Controls. South Med J. 2017 11; 110(11):709-713. PMID: 29100221; PMCID: PMC5859930.
      Citations:    Fields:    Translation:HumansCells
    13. Agarwal N, Iyer D, Gabbi C, Saha P, Patel SG, Mo Q, Chang B, Goswami B, Kopp JB, Lewis DE, Balasubramanyam A, Schubert U. HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRa and PPARa dysregulation: implications for HIV-specific pathogenesis of NAFLD. Sci Rep. 2017 10 17; 7(1):13362. PMID: 29042644; PMCID: PMC5645472.
      Citations: 14     Fields:    Translation:AnimalsCells
    14. Khan IM, Pokharel Y, Dadu RT, Lewis DE, Hoogeveen RC, Wu H, Ballantyne CM. Postprandial Monocyte Activation in Individuals With Metabolic Syndrome. J Clin Endocrinol Metab. 2016 11; 101(11):4195-4204. PMID: 27575945; PMCID: PMC5095236.
      Citations: 21     Fields:    Translation:HumansCells
    15. Couturier J, Agarwal N, Nehete PN, Baze WB, Barry MA, Jagannadha Sastry K, Balasubramanyam A, Lewis DE. Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques. Retrovirology. 2016 Apr 27; 13:30. PMID: 27117277; PMCID: PMC4847269.
      Citations: 19     Fields:    Translation:AnimalsCells
    16. Shi C, Li H, Couturier JP, Yang K, Guo X, He D, Lewis DE, Zhou X. Allele Specific Expression of MICA Variants in Human Fibroblasts Suggests a Pathogenic Mechanism. Open Rheumatol J. 2015; 9:60-4. PMID: 26322142; PMCID: PMC4550945.
      Citations: 7     
    17. Shiue LH, Couturier J, Lewis DE, Wei C, Ni X, Duvic M. The effect of extracorporeal photopheresis alone or in combination therapy on circulating CD4(+) Foxp3(+) CD25(-) T cells in patients with leukemic cutaneous T-cell lymphoma. Photodermatol Photoimmunol Photomed. 2015 Jul; 31(4):184-94. PMID: 25772268; PMCID: PMC4504772.
      Citations: 7     Fields:    Translation:HumansCells
    18. Couturier J, Suliburk JW, Brown JM, Luke DJ, Agarwal N, Yu X, Nguyen C, Iyer D, Kozinetz CA, Overbeek PA, Metzker ML, Balasubramanyam A, Lewis DE. Human adipose tissue as a reservoir for memory CD4+ T cells and HIV. AIDS. 2015 Mar 27; 29(6):667-74. PMID: 25849830; PMCID: PMC4389783.
      Citations: 63     Fields:    Translation:HumansCells
    19. Budhiraja S, Liu H, Couturier J, Malovannaya A, Qin J, Lewis DE, Rice AP. Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function. J Virol. 2015 Apr; 89(7):3557-67. PMID: 25589658; PMCID: PMC4403413.
      Citations: 16     Fields:    Translation:HumansCells
    20. Lin L, Couturier J, Yu X, Medina MA, Kozinetz CA, Lewis DE. Granzyme B secretion by human memory CD4 T cells is less strictly regulated compared to memory CD8 T cells. BMC Immunol. 2014 Sep 24; 15:36. PMID: 25245659; PMCID: PMC4195902.
      Citations: 25     Fields:    Translation:HumansCells
    21. Couturier J, Hutchison AT, Medina MA, Gingaras C, Urvil P, Yu X, Nguyen C, Mahale P, Lin L, Kozinetz CA, Schmitz JE, Kimata JT, Savidge TC, Lewis DE. HIV replication in conjunction with granzyme B production by CCR5+ memory CD4 T cells: Implications for bystander cell and tissue pathologies. Virology. 2014 Aug; 462-463:175-88. PMID: 24999042; PMCID: PMC4158656.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    22. Agarwal N, Iyer D, Patel SG, Sekhar RV, Phillips TM, Schubert U, Oplt T, Buras ED, Samson SL, Couturier J, Lewis DE, Rodriguez-Barradas MC, Jahoor F, Kino T, Kopp JB, Balasubramanyam A. HIV-1 Vpr induces adipose dysfunction in vivo through reciprocal effects on PPAR/GR co-regulation. Sci Transl Med. 2013 Nov 27; 5(213):213ra164. PMID: 24285483; PMCID: PMC4009012.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    23. Cimo AM, Ahmed Z, McIntyre BW, Lewis DE, Ladbury JE. CD25 and CD69 induction by a4?1 outside-in signalling requires TCR early signalling complex proteins. Biochem J. 2013 Aug 15; 454(1):109-21. PMID: 23758320; PMCID: PMC3749870.
      Citations: 3     Fields:    Translation:HumansCells
    24. Misra R, Chandra P, Riechman SE, Long DM, Shinde S, Pownall HJ, Coraza I, Lewis DE, Sekhar RV, Balasubramanyam A. Relationship of ethnicity and CD4 Count with glucose metabolism among HIV patients on Highly-Active Antiretroviral Therapy (HAART). BMC Endocr Disord. 2013 Apr 22; 13:13. PMID: 23607267; PMCID: PMC3751670.
      Citations: 5     Fields:    
    25. Elhaj M, Charles J, Pedroza C, Liu X, Zhou X, Estrada-Y-Martin RM, Gonzalez EB, Lewis DE, Draeger HT, Kim S, Arnett FC, Mayes MD, Assassi S. Can serum surfactant protein D or CC-chemokine ligand 18 predict outcome of interstitial lung disease in patients with early systemic sclerosis? J Rheumatol. 2013 Jul; 40(7):1114-20. PMID: 23588945; PMCID: PMC3728890.
      Citations: 17     Fields:    Translation:Humans
    26. Wu H, Chen L, Zhou Q, Zhang X, Berger S, Bi J, Lewis DE, Xia Y, Zhang W. Aqp2-expressing cells give rise to renal intercalated cells. J Am Soc Nephrol. 2013 Feb; 24(2):243-52. PMID: 23308014; PMCID: PMC3559490.
      Citations: 43     Fields:    Translation:AnimalsCells
    27. Shi G, Tang H, Lewis DE, Song XT, Zhu W. An effective vaccination approach augments anti-HIV systemic and vaginal immunity in mice with decreased HIV-1 susceptible a4?7high CD4+ T cells. Curr HIV Res. 2013 Jan; 11(1):56-66. PMID: 23157585; PMCID: PMC3717605.
      Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    28. Lewis DE. Sweat the small stuff. Cytometry A. 2012 Nov; 81(11):933-4. PMID: 22899596.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    29. Tassiopoulos K, Landay A, Collier AC, Connick E, Deeks SG, Hunt P, Lewis DE, Wilson C, Bosch R. CD28-negative CD4+ and CD8+ T cells in antiretroviral therapy-naive HIV-infected adults enrolled in adult clinical trials group studies. J Infect Dis. 2012 Jun; 205(11):1730-8. PMID: 22448010; PMCID: PMC3415854.
      Citations: 19     Fields:    Translation:HumansCells
    30. Medina MA, Couturier J, Feske ML, Mahne AE, Turner M, Yu X, Kozinetz CA, Orozco AF, Hutchison AT, Savidge TC, Rodgers JR, Lewis DE. Granzyme B- and Fas ligand-mediated cytotoxic function induced by mitogenic CD28 stimulation of human memory CD4+ T cells. J Leukoc Biol. 2012 May; 91(5):759-71. PMID: 22416257; PMCID: PMC3336770.
      Citations: 9     Fields:    Translation:HumansCells
    31. Feske ML, Medina M, Graviss EA, Lewis DE. IL-7 addition increases spot size and number as measured by T-SPOT.TB (?). Methods Mol Biol. 2012; 792:229-41. PMID: 21956514.
      Citations: 3     Fields:    Translation:HumansCells
    32. Couturier J, Patel SG, Iyer D, Balasubramanyam A, Lewis DE. Human monocytes accelerate proliferation and blunt differentiation of preadipocytes in association with suppression of C/EBP? mRNA. Obesity (Silver Spring). 2012 Feb; 20(2):253-62. PMID: 21869759; PMCID: PMC4364279.
      Citations: 2     Fields:    Translation:HumansCells
    33. Montes M, Sanchez C, Lewis DE, Graviss EA, Seas C, Gotuzzo E, White AC. Normalization of FoxP3(+) regulatory T cells in response to effective antiretroviral therapy. J Infect Dis. 2011 Feb 15; 203(4):496-9. PMID: 21177309; PMCID: PMC3071220.
      Citations: 18     Fields:    Translation:HumansCells
    34. Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y. Detrimental effects of adenosine signaling in sickle cell disease. Nat Med. 2011 Jan; 17(1):79-86. PMID: 21170046; PMCID: PMC4838392.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    35. Orozco AF, Lewis DE. Flow cytometric analysis of circulating microparticles in plasma. Cytometry A. 2010 Jun; 77(6):502-14. PMID: 20235276; PMCID: PMC2919894.
      Citations: 127     Fields:    Translation:HumansCells
    36. Pantenburg B, Castellanos-Gonzalez A, Dann SM, Connelly RL, Lewis DE, Ward HD, White AC. Human CD8(+) T cells clear Cryptosporidium parvum from infected intestinal epithelial cells. Am J Trop Med Hyg. 2010 Apr; 82(4):600-7. PMID: 20348507; PMCID: PMC2844566.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    37. Montes M, Sanchez C, Verdonck K, Lake JE, Gonzalez E, Lopez G, Terashima A, Nolan T, Lewis DE, Gotuzzo E, White AC. Regulatory T cell expansion in HTLV-1 and strongyloidiasis co-infection is associated with reduced IL-5 responses to Strongyloides stercoralis antigen. PLoS Negl Trop Dis. 2009 Jun 09; 3(6):e456. PMID: 19513105; PMCID: PMC2686100.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    38. Orozco AF, Jorgez CJ, Horne C, Marquez-Do DA, Chapman MR, Rodgers JR, Bischoff FZ, Lewis DE. Membrane protected apoptotic trophoblast microparticles contain nucleic acids: relevance to preeclampsia. Am J Pathol. 2008 Dec; 173(6):1595-608. PMID: 18974299; PMCID: PMC2626372.
      Citations: 25     Fields:    Translation:HumansCells
    39. Feske M, Nudelman RJ, Medina M, Lew J, Singh M, Couturier J, Graviss EA, Lewis DE. Enhancement of human antigen-specific memory T-cell responses by interleukin-7 may improve accuracy in diagnosing tuberculosis. Clin Vaccine Immunol. 2008 Oct; 15(10):1616-22. PMID: 18753334; PMCID: PMC2565935.
      Citations: 12     Fields:    Translation:HumansCells
    40. Singh M, Basu S, Camell C, Couturier J, Nudelman RJ, Medina MA, Rodgers JR, Lewis DE. Selective expansion of memory CD4(+) T cells by mitogenic human CD28 generates inflammatory cytokines and regulatory T cells. Eur J Immunol. 2008 Jun; 38(6):1522-32. PMID: 18446791; PMCID: PMC2735850.
      Citations: 5     Fields:    Translation:HumansCells
    41. Castellanos-Gonzalez A, Yancey LS, Wang HC, Pantenburg B, Liscum KR, Lewis DE, White AC. Cryptosporidium infection of human intestinal epithelial cells increases expression of osteoprotegerin: a novel mechanism for evasion of host defenses. J Infect Dis. 2008 Mar 15; 197(6):916-23. PMID: 18288900.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    42. Pantenburg B, Dann SM, Wang HC, Robinson P, Castellanos-Gonzalez A, Lewis DE, White AC. Intestinal immune response to human Cryptosporidium sp. infection. Infect Immun. 2008 Jan; 76(1):23-9. PMID: 17967863; PMCID: PMC2223661.
      Citations: 29     Fields:    Translation:HumansAnimals
    43. Preidis GA, Wang HC, Lewis DE, Castellanos-Gonzalez A, Rogers KA, Graviss EA, Ward HD, White AC. Seropositive human subjects produce interferon gamma after stimulation with recombinant Cryptosporidium hominis gp15. Am J Trop Med Hyg. 2007 Sep; 77(3):583-5. PMID: 17827383.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    44. Lewis DE, Gross KL, Diez MM, Martinez ML, Lukefahr HN, Kozinetz CA, Arduino RC. CD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV. J Transl Med. 2007 Jan 30; 5:9. PMID: 17263884; PMCID: PMC1800849.
      Citations: 1     Fields:    Translation:HumansCells
    45. Lewis DE. HIV vaccines: the future looks promising. Res Initiat Treat Action. 2007; 12(2):29-32. PMID: 17489121.
      Citations:    Fields:    Translation:HumansCells
    46. Corry DB, Lewis DE. Cytokine storm and an anti-CD28 monoclonal antibody. N Engl J Med. 2006 Dec 14; 355(24):2592; author reply 2593-4. PMID: 17171820.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    47. Wang HC, Dann SM, Okhuysen PC, Lewis DE, Chappell CL, Adler DG, White AC. High levels of CXCL10 are produced by intestinal epithelial cells in AIDS patients with active cryptosporidiosis but not after reconstitution of immunity. Infect Immun. 2007 Jan; 75(1):481-7. PMID: 17043107; PMCID: PMC1828373.
      Citations: 15     Fields:    Translation:HumansAnimals
    48. Montes M, Jaensson EA, Orozco AF, Lewis DE, Corry DB. A general method for bead-enhanced quantitation by flow cytometry. J Immunol Methods. 2006 Dec 20; 317(1-2):45-55. PMID: 17067632; PMCID: PMC2680352.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    49. Jorgez CJ, Dang DD, Simpson JL, Lewis DE, Bischoff FZ. Quantity versus quality: optimal methods for cell-free DNA isolation from plasma of pregnant women. Genet Med. 2006 Oct; 8(10):615-9. PMID: 17079877.
      Citations: 26     Fields:    Translation:Humans
    50. Orozco AF, Bischoff FZ, Horne C, Popek E, Simpson JL, Lewis DE. Hypoxia-induced membrane-bound apoptotic DNA particles: potential mechanism of fetal DNA in maternal plasma. Ann N Y Acad Sci. 2006 Sep; 1075:57-62. PMID: 17108192.
      Citations: 13     Fields:    Translation:HumansCells
    51. Montes M, Lewis DE, Sanchez C, Lopez de Castilla D, Graviss EA, Seas C, Gotuzzo E, White AC. Foxp3+ regulatory T cells in antiretroviral-naive HIV patients. AIDS. 2006 Aug 01; 20(12):1669-71. PMID: 16868450.
      Citations: 21     Fields:    Translation:HumansCells
    52. Dann SM, Wang HC, Gambarin KJ, Actor JK, Robinson P, Lewis DE, Caillat-Zucman S, White AC. Interleukin-15 activates human natural killer cells to clear the intestinal protozoan cryptosporidium. J Infect Dis. 2005 Oct 01; 192(7):1294-302. PMID: 16136475.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    53. Okhuysen PC, Chappell CL, Lewis DE, Robinson P, White AC. Treatment of chronic cryptosporidiosis in AIDS with rIL-12 induces an immune response associated with improvement but severe side-effects. AIDS. 2005 Aug 12; 19(12):1333-4. PMID: 16052094.
      Citations: 1     Fields:    Translation:Humans
    54. Bischoff FZ, Lewis DE, Simpson JL. Cell-free fetal DNA in maternal blood: kinetics, source and structure. Hum Reprod Update. 2005 Jan-Feb; 11(1):59-67. PMID: 15569699.
      Citations: 43     Fields:    Translation:HumansCells
    55. Grumelli S, Corry DB, Song LZ, Song L, Green L, Huh J, Hacken J, Espada R, Bag R, Lewis DE, Kheradmand F. An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med. 2004 Oct; 1(1):e8. PMID: 15526056; PMCID: PMC523885.
      Citations: 178     Fields:    Translation:HumansCells
    56. Blutt SE, Crawford SE, Warfield KL, Lewis DE, Estes MK, Conner ME. The VP7 outer capsid protein of rotavirus induces polyclonal B-cell activation. J Virol. 2004 Jul; 78(13):6974-81. PMID: 15194774; PMCID: PMC421650.
      Citations: 17     Fields:    Translation:AnimalsCells
    57. Lewis DE, Merched-Sauvage M, Weyand CM, Vallejo AN, Goronzy JJ. Tumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription. J Biol Chem. 2004 Jul 09; 279(28):29130-8. PMID: 15128741.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    58. Ling PD, Vilchez RA, Keitel WA, Poston DG, Peng RS, White ZS, Visnegarwala F, Lewis DE, Butel JS. Epstein-Barr virus DNA loads in adult human immunodeficiency virus type 1-infected patients receiving highly active antiretroviral therapy. Clin Infect Dis. 2003 Nov 01; 37(9):1244-9. PMID: 14557970.
      Citations: 26     Fields:    Translation:HumansCells
    59. Robinson P, Okhuysen PC, Chappell CL, Weinstock JV, Lewis DE, Actor JK, White AC. Substance P expression correlates with severity of diarrhea in cryptosporidiosis. J Infect Dis. 2003 Jul 15; 188(2):290-6. PMID: 12854086.
      Citations: 11     Fields:    Translation:HumansAnimals
    60. Lednicky JA, Vilchez RA, Keitel WA, Visnegarwala F, White ZS, Kozinetz CA, Lewis DE, Butel JS. Polyomavirus JCV excretion and genotype analysis in HIV-infected patients receiving highly active antiretroviral therapy. AIDS. 2003 Apr 11; 17(6):801-7. PMID: 12660526.
      Citations: 10     Fields:    Translation:HumansCells
    61. Bischoff FZ, Dang DX, Marquez-Do D, Martinez D, Horne C, Lewis DE, Simpson JL. Detecting fetal DNA from dried maternal blood spots: another step towards broad scale non-invasive prenatal genetic screening and feasible testing. Reprod Biomed Online. 2003 Apr-May; 6(3):349-51. PMID: 12735873.
      Citations: 5     Fields:    Translation:HumansCells
    62. Bischoff FZ, Hahn S, Johnson KL, Simpson JL, Bianchi DW, Lewis DE, Weber WD, Klinger K, Elias S, Jackson LG, Evans MI, Holzgreve W, de la Cruz F. Intact fetal cells in maternal plasma: are they really there? Lancet. 2003 Jan 11; 361(9352):139-40. PMID: 12531583.
      Citations: 6     Fields:    Translation:Humans
    63. Bischoff FZ, Sinacori MK, Dang DD, Marquez-Do D, Horne C, Lewis DE, Simpson JL. Cell-free fetal DNA and intact fetal cells in maternal blood circulation: implications for first and second trimester non-invasive prenatal diagnosis. Hum Reprod Update. 2002 Nov-Dec; 8(6):493-500. PMID: 12498419.
      Citations: 16     Fields:    Translation:Humans
    64. Xie Q, Khaoustov VI, Chung CC, Sohn J, Krishnan B, Lewis DE, Yoffe B. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep; 36(3):592-601. PMID: 12198651.
      Citations: 134     Fields:    Translation:HumansCells
    65. Robinson P, White AC, Lewis DE, Thornby J, David E, Weinstock J. Sequential expression of the neuropeptides substance P and somatostatin in granulomas associated with murine cysticercosis. Infect Immun. 2002 Aug; 70(8):4534-8. PMID: 12117965; PMCID: PMC128166.
      Citations: 15     Fields:    Translation:Animals
    66. Blutt SE, Warfield KL, Lewis DE, Conner ME. Early response to rotavirus infection involves massive B cell activation. J Immunol. 2002 Jun 01; 168(11):5716-21. PMID: 12023371.
      Citations: 24     Fields:    Translation:AnimalsCells
    67. Manotaya S, Elias S, Lewis DE, Simpson JL, Bischoff FZ. Evaluation of a culture system for enrichment of CD34+ hematopoietic progenitor cells present in maternal blood. Fetal Diagn Ther. 2002 Mar-Apr; 17(2):90-6. PMID: 11844912.
      Citations: 1     Fields:    Translation:HumansCells
    68. Bischoff FZ, Dang DX, Lewis DE, Simpson JL. Prenatal diagnosis of chromosomal abnormalities using maternal blood. Methods Mol Biol. 2002; 204:243-58. PMID: 12397802.
      Citations:    Fields:    Translation:Humans
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