DNA Breaks, Double-Stranded
"DNA Breaks, Double-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interruptions in the sugar-phosphate backbone of DNA, across both strands adjacently.
Descriptor ID |
D053903
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MeSH Number(s) |
G05.200.210.220
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Concept/Terms |
DNA Breaks, Double-Stranded- DNA Breaks, Double-Stranded
- Break, Double-Stranded DNA
- Breaks, Double-Stranded DNA
- DNA Break, Double-Stranded
- DNA Breaks, Double Stranded
- Double-Stranded DNA Break
- Double Stranded DNA Break
- Double-Strand DNA Breaks
- Break, Double-Strand DNA
- Breaks, Double-Strand DNA
- DNA Break, Double-Strand
- DNA Breaks, Double-Strand
- Double Strand DNA Breaks
- Double-Strand DNA Break
- Double-Stranded DNA Breaks
- Double Stranded DNA Breaks
|
Below are MeSH descriptors whose meaning is more general than "DNA Breaks, Double-Stranded".
Below are MeSH descriptors whose meaning is more specific than "DNA Breaks, Double-Stranded".
This graph shows the total number of publications written about "DNA Breaks, Double-Stranded" by people in this website by year, and whether "DNA Breaks, Double-Stranded" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 2 | 1 | 3 |
2007 | 7 | 1 | 8 |
2008 | 3 | 3 | 6 |
2009 | 6 | 9 | 15 |
2010 | 17 | 6 | 23 |
2011 | 8 | 11 | 19 |
2012 | 8 | 7 | 15 |
2013 | 6 | 7 | 13 |
2014 | 8 | 8 | 16 |
2015 | 5 | 7 | 12 |
2016 | 5 | 12 | 17 |
2017 | 3 | 13 | 16 |
2018 | 4 | 5 | 9 |
2019 | 4 | 8 | 12 |
2020 | 2 | 5 | 7 |
2021 | 5 | 6 | 11 |
2022 | 3 | 3 | 6 |
2023 | 1 | 2 | 3 |
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Below are the most recent publications written about "DNA Breaks, Double-Stranded" by people in Profiles.
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Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs. Nat Struct Mol Biol. 2023 10; 30(10):1456-1467.
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Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma. Neuro Oncol. 2023 07 06; 25(7):1249-1261.
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Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells. Genome Biol. 2023 04 24; 24(1):89.
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MRNIP condensates promote DNA double-strand break sensing and end resection. Nat Commun. 2022 05 12; 13(1):2638.
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Measuring the contributions of helicases to break-induced replication. Methods Enzymol. 2022; 672:339-368.
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Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice. Int J Mol Sci. 2022 Mar 28; 23(7).
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The functional impact of BRCA1 BRCT domain variants using multiplexed DNA double-strand break repair assays. Am J Hum Genet. 2022 04 07; 109(4):618-630.
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Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble. Nat Commun. 2022 01 18; 13(1):359.
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Monitoring Nuclease Activity by X-Ray Scattering Interferometry Using Gold Nanoparticle-Conjugated DNA. Methods Mol Biol. 2022; 2444:183-205.
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Interaction of Wwox with Brca1 and associated complex proteins prevents premature resection at double-strand breaks and aberrant homologous recombination. DNA Repair (Amst). 2022 02; 110:103264.