"Malate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of (S)-malate and NAD+ to oxaloacetate and NADH. EC 1.1.1.37.
| Descriptor ID |
D008291
|
| MeSH Number(s) |
D08.811.682.047.820.496
|
| Concept/Terms |
Malate Dehydrogenase- Malate Dehydrogenase
- Dehydrogenase, Malate
- NAD-Malate Dehydrogenase
- Dehydrogenase, NAD-Malate
- NAD Malate Dehydrogenase
- Malic Dehydrogenase
- Dehydrogenase, Malic
|
Below are MeSH descriptors whose meaning is more general than "Malate Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Malate Dehydrogenase".
This graph shows the total number of publications written about "Malate Dehydrogenase" by people in this website by year, and whether "Malate Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Malate Dehydrogenase" by people in Profiles.
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Targeting Ferroptosis Vulnerability in Synovial Sarcoma: Is It All About ME1? Clin Cancer Res. 2022 08 15; 28(16):3408-3410.
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Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017 02 02; 542(7639):119-123.
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Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy. Am J Hum Genet. 2017 Jan 05; 100(1):151-159.
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Down-regulation of malic enzyme 1 and 2: Sensitizing head and neck squamous cell carcinoma cells to therapy-induced senescence. Head Neck. 2016 04; 38 Suppl 1:E934-40.
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Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy. Circ Res. 2009 Mar 27; 104(6):805-12.
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Localization of the nucleic acid channel regulatory subunit, cytosolic malate dehydrogenase. J Membr Biol. 2008 Nov-Dec; 226(1-3):1-8.
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Proteomic analysis of mouse hypothalamus under simulated microgravity. Neurochem Res. 2008 Nov; 33(11):2335-41.
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Influence of Ramadan-type fasting on enzymes of carbohydrate metabolism and brush border membrane in small intestine and liver of rat used as a model. Br J Nutr. 2006 Dec; 96(6):1087-94.
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Cytosolic malate dehydrogenase confers selectivity of the nucleic acid-conducting channel. Proc Natl Acad Sci U S A. 2002 Feb 05; 99(3):1707-12.
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Leptin stimulates uncoupling protein-2 mRNA expression and Krebs cycle activity and inhibits lipid synthesis in isolated rat white adipocytes. Eur J Biochem. 2000 Oct; 267(19):5952-8.