"Receptor, Notch1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor that interacts with a variety of ligands and regulates SIGNAL TRANSDUCTION PATHWAYS for multiple cellular processes. It is widely expressed during EMBRYOGENESIS and is essential for EMBRYONIC DEVELOPMENT.
| Descriptor ID |
D051881
|
| MeSH Number(s) |
D12.776.543.750.725.500 D12.776.930.770.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Notch1".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch1".
This graph shows the total number of publications written about "Receptor, Notch1" by people in this website by year, and whether "Receptor, Notch1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 5 | 0 | 5 |
| 2012 | 3 | 1 | 4 |
| 2013 | 3 | 1 | 4 |
| 2014 | 2 | 2 | 4 |
| 2015 | 3 | 3 | 6 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 4 | 2 | 6 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 4 | 5 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 4 | 4 |
| 2025 | 1 | 2 | 3 |
| 2026 | 2 | 1 | 3 |
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Below are the most recent publications written about "Receptor, Notch1" by people in Profiles.
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FGFR3::TACC3 Fusion and NOTCH1 Loss-of-Function in a Case of HPV-Associated Sinonasal Squamous Cell Carcinoma: Diagnostic Challenge and Implications for Targeted Therapy. Head Neck Pathol. 2026 Jun 30; 20(1).
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Inhibition of the Phosphatidylinositol-3 Kinase Pathway Using Bimiralisib in Loss-of-Function NOTCH1-Mutant Head and Neck Cancer. Oncologist. 2022 12 09; 27(12):1004-e926.
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The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis. Cells. 2021 08 25; 10(9).
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Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation. Genome Biol. 2020 09 15; 21(1):247.
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Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia. Blood Cancer Discov. 2020 09; 1(2):178-197.
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Notch-1-PTEN-ERK1/2 signaling axis promotes HER2+ breast cancer cell proliferation and stem cell survival. Oncogene. 2018 08; 37(33):4489-4504.
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Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1511-E1519.
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Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model. J Clin Invest. 2016 07 01; 126(7):2626-41.
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Requirement for ssbp2 in hematopoietic stem cell maintenance and stress response. J Immunol. 2014 Nov 01; 193(9):4654-62.
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Notch activation as a driver of osteogenic sarcoma. Cancer Cell. 2014 Sep 08; 26(3):390-401.