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KEPING XIE

TitleProfessor
InstitutionMD Anderson
DepartmentGastroenterology Hepatology & Nutrition
Address7435 Fannin St
Houston TX 77054-1901
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Xue J, Zhou A, Wu Y, Morris SA, Lin K, Amin S, Verhaak R, Fuller G, Xie K, Heimberger AB, Huang S. miR-182-5p Induced by STAT3 Activation Promotes Glioma Tumorigenesis. Cancer Res. 2016 Jul 15; 76(14):4293-304. PMID: 27246830; PMCID: PMC5033679 [Available on 07/15/17].
    2. Yu G, Yu W, Jin G, Xu D, Chen Y, Xia T, Yu A, Fang W, Zhang X, Li Z, Xie K. PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma. Mol Cancer. 2015; 14(1):193. PMID: 26576639.
      View in: PubMed
    3. Xie D, Cui J, Xia T, Jia Z, Wang L, Wei W, Zhu A, Gao Y, Xie K, Quan M. Hippo transducer TAZ promotes epithelial mesenchymal transition and supports pancreatic cancer progression. Oncotarget. 2015 Nov 3; 6(34):35949-63. PMID: 26416426.
      View in: PubMed
    4. Quan M, Cui J, Xia T, Jia Z, Xie D, Wei D, Huang S, Huang Q, Zheng S, Xie K. Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/?-Catenin Signaling. Cancer Res. 2015 Nov 15; 75(22):4778-89. PMID: 26483206.
      View in: PubMed
    5. Sun H, Tang H, Xie D, Jia Z, Ma Z, Wei D, Mishra L, Gao Y, Zheng S, Xie K, Peng Z. Krüppel-like Factor 4 Blocks Hepatocellular Carcinoma Dedifferentiation and Progression through Activation of Hepatocyte Nuclear Factor-6. Clin Cancer Res. 2016 Jan 15; 22(2):502-12. PMID: 26338995.
      View in: PubMed
    6. Xue J, Zhou A, Tan C, Wu Y, Lee HT, Li W, Xie K, Huang S. Forkhead Box M1 Is Essential for Nuclear Localization of Glioma-associated Oncogene Homolog 1 in Glioblastoma Multiforme Cells by Promoting Importin-7 Expression. J Biol Chem. 2015 Jul 24; 290(30):18662-70. PMID: 26085085.
      View in: PubMed
    7. Zhu M, Guo J, Li W, Lu Y, Fu S, Xie X, Xia H, Dong X, Chen Y, Quan M, Zheng S, Xie K, Li M. Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells. Oncotarget. 2015 May 20; 6(14):12196-208. PMID: 25682869.
      View in: PubMed
    8. Yu G, Fang W, Xia T, Chen Y, Gao Y, Jiao X, Huang S, Wang J, Li Z, Xie K. Metformin potentiates rapamycin and cisplatin in gastric cancer in mice. Oncotarget. 2015 May 20; 6(14):12748-62. PMID: 25909163.
      View in: PubMed
    9. Yu G, Zhou A, Xue J, Huang C, Zhang X, Kang SH, Chiu WT, Tan C, Xie K, Wang J, Huang S. FoxM1 promotes breast tumorigenesis by activating PDGF-A and forming a positive feedback loop with the PDGF/AKT signaling pathway. Oncotarget. 2015 May 10; 6(13):11281-94. PMID: 25869208.
      View in: PubMed
    10. Lee HT, Xue J, Chou PC, Zhou A, Yang P, Conrad CA, Aldape KD, Priebe W, Patterson C, Sawaya R, Xie K, Huang S. Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells. Oncotarget. 2015 Apr 30; 6(12):10016-29. PMID: 25881542.
      View in: PubMed
    11. Zhang CL, Zeng T, Zhao XL, Xie KQ. Garlic Oil Suppressed Nitrosodiethylamine-Induced Hepatocarcinoma in Rats by Inhibiting PI3K-AKT-NF-?B Pathway. Int J Biol Sci. 2015; 11(6):643-51. PMID: 25999787.
      View in: PubMed
    12. Yao JC, Phan AT, Hess K, Fogelman D, Jacobs C, Dagohoy C, Leary C, Xie K, Ng CS. Perfusion computed tomography as functional biomarker in randomized run-in study of bevacizumab and everolimus in well-differentiated neuroendocrine tumors. Pancreas. 2015 Mar; 44(2):190-7. PMID: 25426617.
      View in: PubMed
    13. Li Z, Guo J, Xie K, Zheng S. Vitamin D receptor signaling and pancreatic cancer cell EMT. Curr Pharm Des. 2015; 21(10):1262-7. PMID: 25506892.
      View in: PubMed
    14. Li Z, Jia Z, Gao Y, Xie D, Wei D, Cui J, Mishra L, Huang S, Zhang Y, Xie K. Activation of vitamin D receptor signaling downregulates the expression of nuclear FOXM1 protein and suppresses pancreatic cancer cell stemness. Clin Cancer Res. 2015 Feb 15; 21(4):844-53. PMID: 25501129.
      View in: PubMed
    15. Shi M, Cui J, Du J, Wei D, Jia Z, Zhang J, Zhu Z, Gao Y, Xie K. A novel KLF4/LDHA signaling pathway regulates aerobic glycolysis in and progression of pancreatic cancer. Clin Cancer Res. 2014 Aug 15; 20(16):4370-80. PMID: 24947925.
      View in: PubMed
    16. Li X, Wang Z, Ma Q, Xu Q, Liu H, Duan W, Lei J, Ma J, Wang X, Lv S, Han L, Li W, Guo J, Guo K, Zhang D, Wu E, Xie K. Sonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancer. Clin Cancer Res. 2014 Aug 15; 20(16):4326-38. PMID: 24947933.
      View in: PubMed
    17. Zeng T, Zhang CL, Song FY, Zhao XL, Xie KQ. CMZ reversed chronic ethanol-induced disturbance of PPAR-? possibly by suppressing oxidative stress and PGC-1? acetylation, and activating the MAPK and GSK3? pathway. PLoS One. 2014; 9(6):e98658. PMID: 24892905.
      View in: PubMed
    18. Zeng T, Zhang CL, Zhao XL, Xie KQ. Pentoxifylline for the treatment of nonalcoholic fatty liver disease: a meta-analysis of randomized double-blind, placebo-controlled studies. Eur J Gastroenterol Hepatol. 2014 Jun; 26(6):646-53. PMID: 24743504.
      View in: PubMed
    19. Li L, Li Z, Kong X, Xie D, Jia Z, Jiang W, Cui J, Du Y, Wei D, Huang S, Xie K. Down-regulation of microRNA-494 via loss of SMAD4 increases FOXM1 and ß-catenin signaling in pancreatic ductal adenocarcinoma cells. Gastroenterology. 2014 Aug; 147(2):485-97.e18. PMID: 24859161.
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    20. Cui J, Shi M, Xie D, Wei D, Jia Z, Zheng S, Gao Y, Huang S, Xie K. FOXM1 promotes the warburg effect and pancreatic cancer progression via transactivation of LDHA expression. Clin Cancer Res. 2014 May 15; 20(10):2595-606. PMID: 24634381.
      View in: PubMed
    21. Huang C, Xie D, Cui J, Li Q, Gao Y, Xie K. FOXM1c promotes pancreatic cancer epithelial-to-mesenchymal transition and metastasis via upregulation of expression of the urokinase plasminogen activator system. Clin Cancer Res. 2014 Mar 15; 20(6):1477-88. PMID: 24452790.
      View in: PubMed
    22. Huang C, Du J, Xie K. FOXM1 and its oncogenic signaling in pancreatic cancer pathogenesis. Biochim Biophys Acta. 2014 Apr; 1845(2):104-16. PMID: 24418574; PMCID: PMC3995850.
    23. Shi M, Xie D, Gaod Y, Xie K. Targeting miRNAs for pancreatic cancer therapy. Curr Pharm Des. 2014; 20(33):5279-86. PMID: 24479803.
      View in: PubMed
    24. Quan M, Wang P, Cui J, Gao Y, Xie K. The roles of FOXM1 in pancreatic stem cells and carcinogenesis. Mol Cancer. 2013; 12:159. PMID: 24325450; PMCID: PMC3924162.
    25. Cui J, Shi M, Quan M, Xie K. Regulation of EMT by KLF4 in gastrointestinal cancer. Curr Cancer Drug Targets. 2013 Nov; 13(9):986-95. PMID: 24168184; PMCID: PMC4127075.
    26. Zeng T, Zhang CL, Han XY, Zhao S, Xie KQ. Association between CD14-159C>T polymorphisms and the risk for alcoholic liver disease: a meta-analysis. Eur J Gastroenterol Hepatol. 2013 Oct; 25(10):1183-9. PMID: 23587862.
      View in: PubMed
    27. Shi M, Cui J, Xie K. Signaling of miRNAs-FOXM1 in cancer and potential targeted therapy. Curr Drug Targets. 2013 Sep; 14(10):1192-202. PMID: 23834153.
      View in: PubMed
    28. Jiang Y, DiVittore NA, Young MM, Jia Z, Xie K, Ritty TM, Kester M, Fox TE. Altered sphingolipid metabolism in patients with metastatic pancreatic cancer. Biomolecules. 2013; 3(3):435-48. PMID: 24970174.
      View in: PubMed
    29. Li L, Du Y, Kong X, Li Z, Jia Z, Cui J, Gao J, Wang G, Xie K. Lamin B1 is a novel therapeutic target of betulinic acid in pancreatic cancer. Clin Cancer Res. 2013 Sep 1; 19(17):4651-61. PMID: 23857605; PMCID: PMC3800003.
    30. Zeng T, Zhang CL, Song FY, Zhao XL, Yu LH, Zhu ZP, Xie KQ. The activation of HO-1/Nrf-2 contributes to the protective effects of diallyl disulfide (DADS) against ethanol-induced oxidative stress. Biochim Biophys Acta. 2013 Oct; 1830(10):4848-59. PMID: 23816986.
      View in: PubMed
    31. Zeng T, Li Y, Zhang CL, Yu LH, Zhu ZP, Zhao XL, Xie KQ. Garlic oil suppressed the hematological disorders induced by chemotherapy and radiotherapy in tumor-bearing mice. J Food Sci. 2013 Jun; 78(6):H936-42. PMID: 23772706.
      View in: PubMed
    32. Kong X, Li L, Li Z, Le X, Huang C, Jia Z, Cui J, Huang S, Wang L, Xie K. Dysregulated expression of FOXM1 isoforms drives progression of pancreatic cancer. Cancer Res. 2013 Jul 1; 73(13):3987-96. PMID: 23598278; PMCID: PMC3702645.
    33. Zeng T, Guo FF, Zhang CL, Song FY, Zhao XL, Xie KQ. Roles of cytochrome P4502E1 gene polymorphisms and the risks of alcoholic liver disease: a meta-analysis. PLoS One. 2013; 8(1):e54188. PMID: 23335995.
      View in: PubMed
    34. Guo K, Ma Q, Li J, Wang Z, Shan T, Li W, Xu Q, Xie K. Interaction of the sympathetic nerve with pancreatic cancer cells promotes perineural invasion through the activation of STAT3 signaling. Mol Cancer Ther. 2013 Mar; 12(3):264-73. PMID: 23288783.
      View in: PubMed
    35. Huang C, Xie K. Analysis of the potential for pancreatic cancer metastasis in vitro and in vivo. Methods Mol Biol. 2013; 980:301-19. PMID: 23359162.
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    36. Li D, Wei P, Peng Z, Huang C, Tang H, Jia Z, Cui J, Le X, Huang S, Xie K. The critical role of dysregulated FOXM1-PLAUR signaling in human colon cancer progression and metastasis. Clin Cancer Res. 2013 Jan 1; 19(1):62-72. PMID: 23136192; PMCID: PMC3537853.
    37. Wang L, Liu H, Chen X, Zhang M, Xie K, Ma Q. Immune sculpting of norepinephrine on MHC-I, B7-1, IDO and B7-H1 expression and regulation of proliferation and invasion in pancreatic carcinoma cells. PLoS One. 2012; 7(9):e45491. PMID: 23029049; PMCID: PMC3446877.
    38. Kong X, Li L, Li Z, Xie K. Targeted destruction of the orchestration of the pancreatic stroma and tumor cells in pancreatic cancer cases: molecular basis for therapeutic implications. Cytokine Growth Factor Rev. 2012 Dec; 23(6):343-56. PMID: 22749856; PMCID: PMC3505269.
    39. Li Q, Gao Y, Jia Z, Mishra L, Guo K, Li Z, Le X, Wei D, Huang S, Xie K. Dysregulated Krüppel-like factor 4 and vitamin D receptor signaling contribute to progression of hepatocellular carcinoma. Gastroenterology. 2012 Sep; 143(3):799-810.e1-2. PMID: 22677193.
      View in: PubMed
    40. Zeng T, Zhang CL, Song FY, Zhao XL, Yu LH, Zhu ZP, Xie KQ. PI3K/Akt pathway activation was involved in acute ethanol-induced fatty liver in mice. Toxicology. 2012 Jun 14; 296(1-3):56-66. PMID: 22459179.
      View in: PubMed
    41. Zhang CL, Zeng T, Zhao XL, Yu LH, Zhu ZP, Xie KQ. Protective effects of garlic oil on hepatocarcinoma induced by N-nitrosodiethylamine in rats. Int J Biol Sci. 2012; 8(3):363-74. PMID: 22393308.
      View in: PubMed
    42. Huang C, Xie K. Crosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesis. Cytokine Growth Factor Rev. 2012 Feb-Apr; 23(1-2):25-35. PMID: 22342309.
      View in: PubMed
    43. Li W, Ma Q, Liu J, Han L, Ma G, Liu H, Shan T, Xie K, Wu E. Hyperglycemia as a mechanism of pancreatic cancer metastasis. Front Biosci (Landmark Ed). 2012; 17:1761-74. PMID: 22201834.
      View in: PubMed
    44. Cui J, Jiang W, Wang S, Wang L, Xie K. Role of Wnt/?-catenin signaling in drug resistance of pancreatic cancer. Curr Pharm Des. 2012; 18(17):2464-71. PMID: 22372504.
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    45. Huang C, Qiu Z, Wang L, Peng Z, Jia Z, Logsdon CD, Le X, Wei D, Huang S, Xie K. A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis. Cancer Res. 2012 Feb 1; 72(3):655-65. PMID: 22194465; PMCID: PMC3271134.
    46. Li Q, Jia Z, Wang L, Kong X, Li Q, Guo K, Tan D, Le X, Wei D, Huang S, Mishra L, Xie K. Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice. Gastroenterology. 2012 Mar; 142(3):531-42. PMID: 22155367; PMCID: PMC3477581.
    47. Zhang N, Wei P, Gong A, Chiu WT, Lee HT, Colman H, Huang H, Xue J, Liu M, Wang Y, Sawaya R, Xie K, Yung WK, Medema RH, He X, Huang S. FoxM1 promotes ?-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis. Cancer Cell. 2011 Oct 18; 20(4):427-42. PMID: 22014570; PMCID: PMC3199318.
    48. Pei JJ, Guo S, Zhang CL, Yu LH, Zhu ZP, Xie KQ, Zhao XL. [The effects of tea polyphenols on the injury of fibrinolytic functions induced by high-methionine dietary in rats]. Zhonghua Yu Fang Yi Xue Za Zhi. 2011 Oct; 45(10):929-33. PMID: 22321596.
      View in: PubMed
    49. Zhong ZX, Chen JJ, Bi Y, Zeng T, Zhu ZP, Zhang XQ, Han XY, Xie KQ, Zhao XL. [Effects of 1-bromopropane exposure on cognitive function in rats]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2011 Aug; 29(8):593-6. PMID: 22335157.
      View in: PubMed
    50. Gao Y, Jia Z, Kong X, Li Q, Chang DZ, Wei D, Le X, Suyun H, Huang S, Wang L, Xie K. Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesis. Cancer Res. 2011 Aug 1; 71(15):5182-93. PMID: 21673052; PMCID: PMC3245664.
    51. Chiu WT, Lee HT, Huang FJ, Aldape KD, Yao J, Steeg PS, Chou CY, Lu Z, Xie K, Huang S. Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by stat3 inhibition. Cancer Res. 2011 Jul 15; 71(14):4932-43. PMID: 21622714; PMCID: PMC4170798.
    52. Li D, Peng Z, Tang H, Wei P, Kong X, Yan D, Huang F, Li Q, Le X, Li Q, Xie K. KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis. Clin Cancer Res. 2011 Jun 1; 17(11):3558-68. PMID: 21531817; PMCID: PMC3107880.
    53. Wei D, Wang L, Kanai M, Jia Z, Le X, Li Q, Wang H, Xie K. KLF4? up-regulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer. Gastroenterology. 2010 Dec; 139(6):2135-45. PMID: 20727893; PMCID: PMC3245983.
    54. Zhao S, Dou DD, Zeng T, Wang QS, Zhu ZP, Zhao XL, Xie KQ. [Effects of tacrolimus (FK506) on heat-shock proteins 70, Bcl-2 and Bax expression in nervous tissue of acrylamide-induced rat]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2010 Apr; 28(4):255-9. PMID: 20465949.
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    55. Dai B, Pieper RO, Li D, Wei P, Liu M, Woo SY, Aldape KD, Sawaya R, Xie K, Huang S. FoxM1B regulates NEDD4-1 expression, leading to cellular transformation and full malignant phenotype in immortalized human astrocytes. Cancer Res. 2010 Apr 1; 70(7):2951-61. PMID: 20332230; PMCID: PMC2848915.
    56. Jia Z, Gao Y, Wang L, Li Q, Zhang J, Le X, Wei D, Yao JC, Chang DZ, Huang S, Xie K. Combined treatment of pancreatic cancer with mithramycin A and tolfenamic acid promotes Sp1 degradation and synergistic antitumor activity. Cancer Res. 2010 Feb 1; 70(3):1111-9. PMID: 20086170; PMCID: PMC2840649.
    57. Wang L, Xie K. Nitric oxide and pancreatic cancer pathogenesis, prevention, and treatment. Curr Pharm Des. 2010; 16(4):421-7. PMID: 20236070.
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    58. Hu HT, Ma QY, Zhang D, Shen SG, Han L, Ma YD, Li RF, Xie KP. HIF-1alpha links beta-adrenoceptor agonists and pancreatic cancer cells under normoxic condition. Acta Pharmacol Sin. 2010 Jan; 31(1):102-10. PMID: 20037603; PMCID: PMC4002695.
    59. Li Q, Wei D, Wang L, Wang L, Jia Z, Le X, Gao Y, Huang S, Xie K. Modeling liver metastasis using a tumor cell line derived from an enhanced green fluorescent protein transgenic mouse. Clin Exp Metastasis. 2010; 27(1):11-8. PMID: 19882218.
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    60. Hu W, Hofstetter WL, Li H, Zhou Y, He Y, Pataer A, Wang L, Xie K, Swisher SG, Fang B. Putative tumor-suppressive function of Kruppel-like factor 4 in primary lung carcinoma. Clin Cancer Res. 2009 Sep 15; 15(18):5688-95. PMID: 19737957; PMCID: PMC2745510.
    61. Zheng Y, Xia Y, Hawke D, Halle M, Tremblay ML, Gao X, Zhou XZ, Aldape K, Cobb MH, Xie K, He J, Lu Z. FAK phosphorylation by ERK primes ras-induced tyrosine dephosphorylation of FAK mediated by PIN1 and PTP-PEST. Mol Cell. 2009 Jul 10; 35(1):11-25. PMID: 19595712.
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    62. Gao XC, Yin HY, Zhang CL, Zhu ZP, Yu LH, Xie KQ. [Effects of garlic oil on n-hexane metabolized to 2, 5-hexanedione in mice serum]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2009 May; 27(5):262-5. PMID: 19538836.
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    63. Li Q, Zhang N, Jia Z, Le X, Dai B, Wei D, Huang S, Tan D, Xie K. Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression. Cancer Res. 2009 Apr 15; 69(8):3501-9. PMID: 19351851.
      View in: PubMed
    64. Yu G, Wang J, Chen Y, Wang X, Pan J, Li G, Jia Z, Li Q, Yao JC, Xie K. Overexpression of phosphorylated mammalian target of rapamycin predicts lymph node metastasis and prognosis of chinese patients with gastric cancer. Clin Cancer Res. 2009 Mar 1; 15(5):1821-9. PMID: 19223493.
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    65. Truong CD, Feng W, Li W, Khoury T, Li Q, Alrawi S, Yu Y, Xie K, Yao J, Tan D. Characteristics of Epstein-Barr virus-associated gastric cancer: a study of 235 cases at a comprehensive cancer center in U.S.A. J Exp Clin Cancer Res. 2009; 28:14. PMID: 19192297; PMCID: PMC2642773.
    66. Huang FJ, Steeg PS, Price JE, Chiu WT, Chou PC, Xie K, Sawaya R, Huang S. Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis. Cancer Res. 2008 Dec 1; 68(23):9634-42. PMID: 19047140.
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    67. Zhang Y, Zhang N, Dai B, Liu M, Sawaya R, Xie K, Huang S. FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells. Cancer Res. 2008 Nov 1; 68(21):8733-42. PMID: 18974115; PMCID: PMC2597644.
    68. Peng Z, Tang H, Wang X, Zhou C, Fan J, Wang L, Jia Z, Li Q, Le X, Wei D, Xie K. Inhibition of the growth and metastasis of human colon cancer by restoration of RUNX3 expression in cancer cells. Int J Oncol. 2008 Nov; 33(5):979-84. PMID: 18949360.
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    69. Song FY, Wang QS, Zeng T, Yu LH, Zhu ZP, Xie KQ. [Dynamic study of neurofilament contents in rat's spinal cord induced by 2, 5-hexanedione]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2008 Oct; 26(10):588-91. PMID: 19272251.
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    70. Zeng T, Zhang CL, Zhu ZP, Yu LH, Zhao XL, Xie KQ. Diallyl trisulfide (DATS) effectively attenuated oxidative stress-mediated liver injury and hepatic mitochondrial dysfunction in acute ethanol-exposed mice. Toxicology. 2008 Oct 30; 252(1-3):86-91. PMID: 18755235.
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    71. Fan J, Peng Z, Zhou C, Qiu G, Tang H, Sun Y, Wang X, Li Q, Le X, Xie K. Gene-expression profiling in Chinese patients with colon cancer by coupling experimental and bioinformatic genomewide gene-expression analyses: identification and validation of IFITM3 as a biomarker of early colon carcinogenesis. Cancer. 2008 Jul 15; 113(2):266-75. PMID: 18470904.
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    72. Wang L, Guan X, Zhang J, Jia Z, Wei D, Li Q, Yao J, Xie K. Targeted inhibition of Sp1-mediated transcription for antiangiogenic therapy of metastatic human gastric cancer in orthotopic nude mouse models. Int J Oncol. 2008 Jul; 33(1):161-7. PMID: 18575762.
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    73. Wei D, Kanai M, Jia Z, Le X, Xie K. Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells. Cancer Res. 2008 Jun 15; 68(12):4631-9. PMID: 18559508; PMCID: PMC2481517.
    74. Yu G, Wang J, Chen Y, Wang X, Pan J, Li Q, Xie K. Tissue microarray analysis reveals strong clinical evidence for a close association between loss of annexin A1 expression and nodal metastasis in gastric cancer. Clin Exp Metastasis. 2008; 25(7):695-702. PMID: 18535914.
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    75. Zhu YJ, Zeng T, Zhu YB, Yu SF, Wang QS, Zhang LP, Guo X, Xie KQ. Effects of acrylamide on the nervous tissue antioxidant system and sciatic nerve electrophysiology in the rat. Neurochem Res. 2008 Nov; 33(11):2310-7. PMID: 18470611.
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    76. Truong CD, Li W, Feng W, Cagle P, Khoury T, Alrawi S, Xie K, Yao J, Tan D. Alpha-methylacyl-CoA racemase expression is upregulated in gastric adenocarcinoma: a study of 249 cases. Int J Clin Exp Pathol. 2008; 1(6):518-23. PMID: 18787636.
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    77. Yuan P, Wang L, Wei D, Zhang J, Jia Z, Li Q, Le X, Wang H, Yao J, Xie K. Therapeutic inhibition of Sp1 expression in growing tumors by mithramycin a correlates directly with potent antiangiogenic effects on human pancreatic cancer. Cancer. 2007 Dec 15; 110(12):2682-90. PMID: 17973266.
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    78. Lin EH, Hassan M, Li Y, Zhao H, Nooka A, Sorenson E, Xie K, Champlin R, Wu X, Li D. Elevated circulating endothelial progenitor marker CD133 messenger RNA levels predict colon cancer recurrence. Cancer. 2007 Aug 1; 110(3):534-42. PMID: 17594720.
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    79. Jia Z, Zhang J, Wei D, Wang L, Yuan P, Le X, Li Q, Yao J, Xie K. Molecular basis of the synergistic antiangiogenic activity of bevacizumab and mithramycin A. Cancer Res. 2007 May 15; 67(10):4878-85. PMID: 17510417.
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    80. Zhang J, Jia Z, Li Q, Wang L, Rashid A, Zhu Z, Evans DB, Vauthey JN, Xie K, Yao JC. Elevated expression of vascular endothelial growth factor correlates with increased angiogenesis and decreased progression-free survival among patients with low-grade neuroendocrine tumors. Cancer. 2007 Apr 15; 109(8):1478-86. PMID: 17340592.
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    81. Wang LW, Li Q, Hua ZL, Zhou F, Keping X, Daoyan W, Yao J, Ajani J. [Expression of transcription factor Sp1 in human gastric cancer tissue and its correlation with prognosis]. Zhonghua Zhong Liu Za Zhi. 2007 Feb; 29(2):107-11. PMID: 17645844.
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    82. Yao JC, Zhang JX, Rashid A, Yeung SC, Szklaruk J, Hess K, Xie K, Ellis L, Abbruzzese JL, Ajani JA. Clinical and in vitro studies of imatinib in advanced carcinoid tumors. Clin Cancer Res. 2007 Jan 1; 13(1):234-40. PMID: 17200360.
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    83. Zhang J, Jiang Y, Jia Z, Li Q, Gong W, Wang L, Wei D, Yao J, Fang S, Xie K. Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer. Clin Exp Metastasis. 2006; 23(7-8):401-10. PMID: 17187227.
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    84. Kanai M, Wei D, Li Q, Jia Z, Ajani J, Le X, Yao J, Xie K. Loss of Krüppel-like factor 4 expression contributes to Sp1 overexpression and human gastric cancer development and progression. Clin Cancer Res. 2006 Nov 1; 12(21):6395-402. PMID: 17085651.
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    85. Peng Z, Wei D, Wang L, Tang H, Zhang J, Le X, Jia Z, Li Q, Xie K. RUNX3 inhibits the expression of vascular endothelial growth factor and reduces the angiogenesis, growth, and metastasis of human gastric cancer. Clin Cancer Res. 2006 Nov 1; 12(21):6386-94. PMID: 17085650.
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    86. Lancaster JR, Xie K. Tumors face NO problems? Cancer Res. 2006 Jul 1; 66(13):6459-62. PMID: 16818612.
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    87. Liu M, Dai B, Kang SH, Ban K, Huang FJ, Lang FF, Aldape KD, Xie TX, Pelloski CE, Xie K, Sawaya R, Huang S. FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells. Cancer Res. 2006 Apr 1; 66(7):3593-602. PMID: 16585184.
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    88. Xie TX, Huang FJ, Aldape KD, Kang SH, Liu M, Gershenwald JE, Xie K, Sawaya R, Huang S. Activation of stat3 in human melanoma promotes brain metastasis. Cancer Res. 2006 Mar 15; 66(6):3188-96. PMID: 16540670.
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    89. Xie K, Wei D, Huang S. Transcriptional anti-angiogenesis therapy of human pancreatic cancer. Cytokine Growth Factor Rev. 2006 Jun; 17(3):147-56. PMID: 16516532.
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    90. Wei D, Kanai M, Huang S, Xie K. Emerging role of KLF4 in human gastrointestinal cancer. Carcinogenesis. 2006 Jan; 27(1):23-31. PMID: 16219632.
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    91. Gong W, Jiang Y, Wang L, Wei D, Yao J, Huang S, Fang S, Xie K. Expression of autocrine motility factor correlates with the angiogenic phenotype of and poor prognosis for human gastric cancer. Clin Cancer Res. 2005 Aug 15; 11(16):5778-83. PMID: 16115916.
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