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STANLEY R HAMILTON

TitleProfessor
InstitutionMD Anderson
DepartmentPathology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Connolly RM, Wang V, Hyman DM, Grivas P, Mitchell EP, Wright JJ, Sharon E, Gray RJ, McShane LM, Rubinstein LV, Patton DR, Williams PM, Hamilton SR, Wang J, Wisinski KB, Tricoli JV, Conley BA, Harris LN, Arteaga CL, O'Dwyer PJ, Chen AP, Flaherty KT. Trastuzumab and Pertuzumab in Patients with Non-Breast/Gastroesophageal HER2-Amplified Tumors: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol J. Clin Cancer Res. 2024 Apr 01; 30(7):1273-1280. PMID: 38433347; PMCID: PMC10984755.
      Citations: 2     Fields:    Translation:Humans
    2. Meric-Bernstam F, Ford JM, O'Dwyer PJ, Shapiro GI, McShane LM, Freidlin B, O'Cearbhaill RE, George S, Glade-Bender J, Lyman GH, Tricoli JV, Patton D, Hamilton SR, Gray RJ, Hawkins DS, Ramineni B, Flaherty KT, Grivas P, Yap TA, Berlin J, Doroshow JH, Harris LN, Moscow JA. National Cancer Institute Combination Therapy Platform Trial with Molecular Analysis for Therapy Choice (ComboMATCH). Clin Cancer Res. 2023 04 14; 29(8):1412-1422. PMID: 36662819; PMCID: PMC10102840.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    3. Liu L, Woo Y, D'Apuzzo M, Melstrom L, Raoof M, Liang Y, Afkhami M, Hamilton SR, Chao J. Immunotherapy-Based Neoadjuvant Treatment of Advanced Microsatellite Instability-High Gastric Cancer: A Case Series. J Natl Compr Canc Netw. 2022 08; 20(8):857-865. PMID: 35948034.
      Citations:    
    4. Bedard PL, Li S, Wisinski KB, Yang ES, Limaye SA, Mitchell EP, Zwiebel JA, Moscow JA, Gray RJ, Wang V, McShane LM, Rubinstein LV, Patton DR, Williams PM, Hamilton SR, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT. Phase II Study of Afatinib in Patients With Tumors With Human Epidermal Growth Factor Receptor 2-Activating Mutations: Results From the National Cancer Institute-Molecular Analysis for Therapy Choice ECOG-ACRIN Trial (EAY131) Subprotocol EAY131-B. JCO Precis Oncol. 2022 07; 6:e2200165. PMID: 35939768; PMCID: PMC9384949.
      Citations:    
    5. Damodaran S, Zhao F, Deming DA, Mitchell EP, Wright JJ, Gray RJ, Wang V, McShane LM, Rubinstein LV, Patton DR, Williams PM, Hamilton SR, Suga JM, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT. Phase II Study of Copanlisib in Patients With Tumors With PIK3CA Mutations: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1F. J Clin Oncol. 2022 05 10; 40(14):1552-1561. PMID: 35133871; PMCID: PMC9084438.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    6. Figueiredo JC, Passarelli MN, Wei W, Ahnen DJ, Morris JS, Corley L, Mehta T, Bartley AN, McKeown-Eyssen G, Bresalier RS, Barry EL, Goel A, Hernandez Mesa G, Hamilton SR, Baron JA. Proliferation, apoptosis and their regulatory protein expression in colorectal adenomas and serrated lesions. PLoS One. 2021; 16(11):e0258878. PMID: 34762658; PMCID: PMC8584700.
      Citations:    Fields:    Translation:Humans
    7. Cleary JM, Wang V, Heist RS, Kopetz ES, Mitchell EP, Zwiebel JA, Kapner KS, Chen HX, Li S, Gray RJ, McShane LM, Rubinstein LV, Patton DR, Meric-Bernstam F, Dillmon MS, Williams PM, Hamilton SR, Conley BA, Aguirre AJ, O'Dwyer PJ, Harris LN, Arteaga CL, Chen AP, Flaherty KT. Differential Outcomes in Codon 12/13 and Codon 61 NRAS-Mutated Cancers in the Phase II NCI-MATCH Trial of Binimetinib in Patients with NRAS-Mutated Tumors. Clin Cancer Res. 2021 06 01; 27(11):2996-3004. PMID: 33637626; PMCID: PMC8542423.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    8. Loree JM, Dowers A, Tu D, Jonker DJ, Edelstein DL, Quinn H, Holtrup F, Price T, Zalcberg JR, Moore MJ, Karapetis CS, O'Callaghan CJ, Waring P, Kennecke HF, Hamilton SR, Kopetz S. Expanded Low Allele Frequency RAS and BRAF V600E Testing in Metastatic Colorectal Cancer as Predictive Biomarkers for Cetuximab in the Randomized CO.17 Trial. Clin Cancer Res. 2021 01 01; 27(1):52-59. PMID: 33087330; PMCID: PMC7785657.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    9. Flaherty KT, Gray RJ, Chen AP, Li S, McShane LM, Patton D, Hamilton SR, Williams PM, Iafrate AJ, Sklar J, Mitchell EP, Harris LN, Takebe N, Sims DJ, Coffey B, Fu T, Routbort M, Zwiebel JA, Rubinstein LV, Little RF, Arteaga CL, Comis R, Abrams JS, O'Dwyer PJ, Conley BA, NCI-MATCH team. Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH). J Clin Oncol. 2020 11 20; 38(33):3883-3894. PMID: 33048619; PMCID: PMC7676882.
      Citations: 47     Fields:    Translation:HumansCTClinical Trials
    10. Advani SM, Swartz MD, Loree J, Davis JS, Sarsashek AM, Lam M, Lee MS, Bressler J, Lopez DS, Daniel CR, Morris V, Shureqi I, Kee B, Dasari A, Vilar E, Overman M, Hamilton S, Maru D, Braithwaite D, Kopetz S. Epidemiology and Molecular-Pathologic Characteristics of CpG Island Methylator Phenotype (CIMP) in Colorectal Cancer. Clin Colorectal Cancer. 2021 06; 20(2):137-147.e1. PMID: 33229221.
      Citations: 4     Fields:    Translation:HumansCells
    11. Zaidi SH, Harrison TA, Phipps AI, Steinfelder R, Trinh QM, Qu C, Banbury BL, Georgeson P, Grasso CS, Giannakis M, Adams JB, Alwers E, Amitay EL, Barfield RT, Berndt SI, Borozan I, Brenner H, Brezina S, Buchanan DD, Cao Y, Chan AT, Chang-Claude J, Connolly CM, Drew DA, Farris AB, Figueiredo JC, French AJ, Fuchs CS, Garraway LA, Gruber S, Guinter MA, Hamilton SR, Heisler LE, Hidaka A, Hopper JL, Huang WY, Huyghe JR, Jenkins MA, Krzyzanowski PM, Lemire M, Lin Y, Luo X, Mardis ER, McPherson JD, Miller JK, Moreno V, Mu XJ, Nishihara R, Papadopoulos N, Pasternack D, Quist MJ, Rafikova A, Reid EEG, Shinbrot E, Shirts BH, Stein LD, Teney CD, Timms L, Um CY, Van Tassel M, Wang X, Wheeler DA, Yung CK, Hsu L, Ogino S, Gsur A, Newcomb PA, Gallinger S, Hoffmeister M, Campbell PT, Thibodeau SN, Sun W, Hudson TJ, Peters U, Harlid S, Van Guelpen B. Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival. Nat Commun. 2020 07 20; 11(1):3644. PMID: 32686686; PMCID: PMC7371703.
      Citations: 20     Fields:    Translation:Humans
    12. Dasari A, Morris VK, Allegra CJ, Atreya C, Benson AB, Boland P, Chung K, Copur MS, Corcoran RB, Deming DA, Dwyer A, Diehn M, Eng C, George TJ, Gollub MJ, Goodwin RA, Hamilton SR, Hechtman JF, Hochster H, Hong TS, Innocenti F, Iqbal A, Jacobs SA, Kennecke HF, Lee JJ, Lieu CH, Lenz HJ, Lindwasser OW, Odisio B, Ou FS, Porter L, Raghav K, Schrag D, Scott AJ, Shi Q, Strickler JH, Venook A, Yaeger R, Yothers G, You YN, Zell JA, Kopetz S, Montagut C. ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal-Anal Task Forces whitepaper. Nat Rev Clin Oncol. 2020 12; 17(12):757-770. PMID: 32632268; PMCID: PMC7790747.
      Citations: 60     Fields:    Translation:Humans
    13. Krishnamurthy S, Sabir S, Ban K, Wu Y, Sheth R, Tam A, Meric-Bernstam F, Shaw K, Mills G, Bassett R, Hamilton S, Hicks M, Gupta S. Comparison of Real-Time Fluorescence Confocal Digital Microscopy With Hematoxylin-Eosin-Stained Sections of Core-Needle Biopsy Specimens. JAMA Netw Open. 2020 03 02; 3(3):e200476. PMID: 32134465; PMCID: PMC7059022.
      Citations: 7     Fields:    Translation:Humans
    14. Azad NS, Gray RJ, Overman MJ, Schoenfeld JD, Mitchell EP, Zwiebel JA, Sharon E, Streicher H, Li S, McShane LM, Rubinstein L, Patton DR, Williams PM, Coffey B, Hamilton SR, Bahary N, Suga JM, Hatoum H, Abrams JS, Conley BA, Arteaga CL, Harris L, O'Dwyer PJ, Chen AP, Flaherty KT. Nivolumab Is Effective in Mismatch Repair-Deficient Noncolorectal Cancers: Results From Arm Z1D-A Subprotocol of the NCI-MATCH (EAY131) Study. J Clin Oncol. 2020 01 20; 38(3):214-222. PMID: 31765263; PMCID: PMC6968795.
      Citations: 33     Fields:    Translation:HumansCTClinical Trials
    15. Advani SM, Shi Q, Overman MJ, Loree JM, Lam M, Morris V, Shureiqi I, Kee B, Dasari A, Vilar E, Sarshekeh AM, Lin HK, Manuel S, Hamilton S, Raghav K, Maru D, Kopetz S, Wang XS. Patient-reported Symptom Outcomes and Microsatellite Instability in Patients With Metastatic Colorectal Cancer. Clin Colorectal Cancer. 2020 03; 19(1):48-56.e2. PMID: 32008976.
      Citations: 1     Fields:    Translation:HumansCells
    16. Korphaisarn K, Morris V, Davis JS, Overman MJ, Fogelman DR, Kee BK, Dasari A, Raghav KPS, Shureiqi I, Trupti M, Wolff RA, Eng C, Menter DG, Hamilton S, Kopetz S. Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma. Br J Cancer. 2019 09; 121(6):505-510. PMID: 31406299; PMCID: PMC6738104.
      Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
    17. Provenzale D, Gupta S, Ahnen DJ, Markowitz AJ, Chung DC, Mayer RJ, Regenbogen SE, Blanco AM, Bray T, Cooper G, Early DS, Ford JM, Giardiello FM, Grady W, Hall MJ, Halverson AL, Hamilton SR, Hampel H, Klapman JB, Larson DW, Lazenby AJ, Llor X, Lynch PM, Mikkelson J, Ness RM, Slavin TP, Sugandha S, Weiss JM, Dwyer MA, Ogba N. NCCN Guidelines Insights: Colorectal Cancer Screening, Version 1.2018. J Natl Compr Canc Netw. 2018 08; 16(8):939-949. PMID: 30099370.
      Citations: 53     Fields:    Translation:HumansPHPublic Health
    18. Hamilton SR. Status of Testing for High-Level Microsatellite Instability/Deficient Mismatch Repair in Colorectal Carcinoma. JAMA Oncol. 2018 02 08; 4(2):e173574. PMID: 29121141.
      Citations:    Fields:    Translation:HumansCells
    19. Hamilton SR. Characterizing the Killer Colorectal Carcinomas. Cancer Cell. 2018 01 08; 33(1):7-9. PMID: 29316434.
      Citations: 1     Fields:    Translation:Humans
    20. Le DT, Hubbard-Lucey VM, Morse MA, Heery CR, Dwyer A, Marsilje TH, Brodsky AN, Chan E, Deming DA, Diaz LA, Fridman WH, Goldberg RM, Hamilton SR, Housseau F, Jaffee EM, Kang SP, Krishnamurthi SS, Lieu CH, Messersmith W, Sears CL, Segal NH, Yang A, Moss RA, Cha E, O'Donnell-Tormey J, Roach N, Davis AQ, McAbee K, Worrall S, Benson AB. A Blueprint to Advance Colorectal Cancer Immunotherapies. Cancer Immunol Res. 2017 11; 5(11):942-949. PMID: 29038296.
      Citations: 31     Fields:    Translation:HumansAnimals
    21. Khoury JD, Wang WL, Prieto VG, Medeiros LJ, Kalhor N, Hameed M, Broaddus R, Hamilton SR. Validation of Immunohistochemical Assays for Integral Biomarkers in the NCI-MATCH EAY131 Clinical Trial. Clin Cancer Res. 2018 02 01; 24(3):521-531. PMID: 28839110; PMCID: PMC5796858.
      Citations: 21     Fields:    Translation:Humans
    22. Korphaisarn K, Morris VK, Overman MJ, Fogelman DR, Kee BK, Raghav KPS, Manuel S, Shureiqi I, Wolff RA, Eng C, Menter D, Hamilton SR, Kopetz S, Dasari A. FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma. Oncotarget. 2017 Jun 13; 8(24):39268-39279. PMID: 28424412; PMCID: PMC5503612.
      Citations: 32     Fields:    Translation:Humans
    23. Sepulveda AR, Hamilton SR, Allegra CJ, Grody W, Cushman-Vokoun AM, Funkhouser WK, Kopetz SE, Lieu C, Lindor NM, Minsky BD, Monzon FA, Sargent DJ, Singh VM, Willis J, Clark J, Colasacco C, Rumble RB, Temple-Smolkin R, Ventura CB, Nowak JA. Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline Summary From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology. J Oncol Pract. 2017 05; 13(5):333-337. PMID: 28350513.
      Citations: 8     Fields:    Translation:Humans
    24. Sepulveda AR, Hamilton SR, Allegra CJ, Grody W, Cushman-Vokoun AM, Funkhouser WK, Kopetz SE, Lieu C, Lindor NM, Minsky BD, Monzon FA, Sargent DJ, Singh VM, Willis J, Clark J, Colasacco C, Bryan Rumble R, Temple-Smolkin R, B Ventura C, Nowak JA. Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology. Arch Pathol Lab Med. 2017 May; 141(5):625-657. PMID: 28165284.
      Citations: 23     Fields:    Translation:Humans
    25. Sepulveda AR, Hamilton SR, Allegra CJ, Grody W, Cushman-Vokoun AM, Funkhouser WK, Kopetz SE, Lieu C, Lindor NM, Minsky BD, Monzon FA, Sargent DJ, Singh VM, Willis J, Clark J, Colasacco C, Rumble RB, Temple-Smolkin R, Ventura CB, Nowak JA. Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology. J Clin Oncol. 2017 May 01; 35(13):1453-1486. PMID: 28165299.
      Citations: 99     Fields:    Translation:Humans
    26. Sepulveda AR, Hamilton SR, Allegra CJ, Grody W, Cushman-Vokoun AM, Funkhouser WK, Kopetz SE, Lieu C, Lindor NM, Minsky BD, Monzon FA, Sargent DJ, Singh VM, Willis J, Clark J, Colasacco C, Rumble RB, Temple-Smolkin R, Ventura CB, Nowak JA. Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and American Society of Clinical Oncology. J Mol Diagn. 2017 03; 19(2):187-225. PMID: 28185757; PMCID: PMC5971222.
      Citations: 42     Fields:    Translation:HumansCells
    27. Sepulveda AR, Hamilton SR, Allegra CJ, Grody W, Cushman-Vokoun AM, Funkhouser WK, Kopetz SE, Lieu C, Lindor NM, Minsky BD, Monzon FA, Sargent DJ, Singh VM, Willis J, Clark J, Colasacco C, Rumble RB, Temple-Smolkin R, Ventura CB, Nowak JA. Molecular Biomarkers for the Evaluation of Colorectal Cancer. Am J Clin Pathol. 2017 03; 147(3):221-260. PMID: 28165529; PMCID: PMC7263311.
      Citations: 6     Fields:    
    28. Sun Y, Ji P, Chen T, Zhou X, Yang D, Guo Y, Liu Y, Hu L, Xia D, Liu Y, Multani AS, Shmulevich I, Kucherlapati R, Kopetz S, Sood AK, Hamilton SR, Sun B, Zhang W. MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer. J Pathol. 2017 Jan; 241(1):67-79. PMID: 27741356; PMCID: PMC5315452.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    29. Overman MJ, Morris V, Moinova H, Manyam G, Ensor J, Lee MS, Eng C, Kee B, Fogelman D, Shroff RT, LaFramboise T, Mazard T, Feng T, Hamilton S, Broom B, Lutterbaugh J, Issa JP, Markowitz SD, Kopetz S. Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin. Oncotarget. 2016 Oct 11; 7(41):67495-67506. PMID: 27542211; PMCID: PMC5341892.
      Citations: 18     Fields:    Translation:HumansCellsCTClinical Trials
    30. Tsikitis VL, Potter A, Mori M, Buckmeier JA, Preece CR, Harrington CA, Bartley AN, Bhattacharyya AK, Hamilton SR, Lance MP, Thompson PA. MicroRNA Signatures of Colonic Polyps on Screening and Histology. Cancer Prev Res (Phila). 2016 Dec; 9(12):942-949. PMID: 27658891; PMCID: PMC5136314.
      Citations: 14     Fields:    Translation:Humans
    31. Thompson PA, Ashbeck EL, Roe DJ, Fales L, Buckmeier J, Wang F, Bhattacharyya A, Hsu CH, Chow SH, Ahnen DJ, Boland CR, Heigh RI, Fay DE, Hamilton SR, Jacobs ET, Martinez EM, Alberts DS, Lance P. Celecoxib for the Prevention of Colorectal Adenomas: Results of a Suspended Randomized Controlled Trial. J Natl Cancer Inst. 2016 12; 108(12). PMID: 27530656; PMCID: PMC6272806.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    32. Thompson PA, Ashbeck EL, Roe DJ, Fales L, Buckmeier J, Wang F, Bhattacharyya A, Hsu CH, Chow HH, Ahnen DJ, Boland CR, Heigh RI, Fay DE, Hamilton SR, Jacobs ET, Martinez ME, Alberts DS, Lance P. Selenium Supplementation for Prevention of Colorectal Adenomas and Risk of Associated Type 2 Diabetes. J Natl Cancer Inst. 2016 12; 108(12). PMID: 27530657; PMCID: PMC6272807.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    33. Stoffel EM, Erichsen R, Pedersen L, Vyberg M, Koeppe E, Crockett SD, Hamilton SR, Baron JA, Fr?slev T, S?rensen HT. Clinical and Molecular Characteristics of Post-Colonoscopy Colorectal Cancer: A Population-based Study. Gastroenterology. 2016 11; 151(5):870-878.e3. PMID: 27443823; PMCID: PMC5159224.
      Citations: 12     Fields:    Translation:HumansCells
    34. Hamilton SR, O'Dwyer PJ, O'Hara MH. Molecular Triage Trials in Colorectal Cancer. Cancer J. 2016 May-Jun; 22(3):218-22. PMID: 27341602.
      Citations:    Fields:    Translation:Humans
    35. Sun Y, Liu Y, Cogdell D, Calin GA, Sun B, Kopetz S, Hamilton SR, Zhang W. Examining plasma microRNA markers for colorectal cancer at different stages. Oncotarget. 2016 Mar 08; 7(10):11434-49. PMID: 26863633; PMCID: PMC4905484.
      Citations: 40     Fields:    Translation:Humans
    36. Erichsen R, Baron JA, Hamilton-Dutoit SJ, Snover DC, Torlakovic EE, Pedersen L, Vyberg M, Hamilton SR, Fr?slev T, S?rensen HT. Increased Risk of Colorectal Cancer Development Among Patients With Serrated Polyps. Gastroenterology. 2016 Apr; 150(4):895-902.e5. PMID: 26677986.
      Citations: 67     Fields:    Translation:Humans
    37. Allegra CJ, Rumble RB, Hamilton SR, Mangu PB, Roach N, Hantel A, Schilsky RL. Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015. J Clin Oncol. 2016 Jan 10; 34(2):179-85. PMID: 26438111.
      Citations: 105     Fields:    Translation:Humans
    38. Estrella JS, Tetzlaff MT, Bassett RL, Patel KP, Williams MD, Curry JL, Rashid A, Hamilton SR, Broaddus RR. Assessment of BRAF V600E Status in Colorectal Carcinoma: Tissue-Specific Discordances between Immunohistochemistry and Sequencing. Mol Cancer Ther. 2015 Dec; 14(12):2887-95. PMID: 26438153.
      Citations: 15     Fields:    Translation:HumansAnimals
    39. Provenzale D, Jasperson K, Ahnen DJ, Aslanian H, Bray T, Cannon JA, David DS, Early DS, Erwin D, Ford JM, Giardiello FM, Gupta S, Halverson AL, Hamilton SR, Hampel H, Ismail MK, Klapman JB, Larson DW, Lazenby AJ, Lynch PM, Mayer RJ, Ness RM, Rao MS, Regenbogen SE, Shike M, Steinbach G, Weinberg D, Dwyer MA, Freedman-Cass DA, Darlow S, National comprehensive cancer netwok. Colorectal Cancer Screening, Version 1.2015. J Natl Compr Canc Netw. 2015 Aug; 13(8):959-68; quiz 968. PMID: 26285241.
      Citations: 29     Fields:    Translation:Humans
    40. Zenali M, deKay J, Liu Z, Hamilton S, Zuo Z, Lu X, Bakkar R, Mills G, Broaddus R. Retrospective Review of MET Gene Mutations. Oncoscience. 2015; 2(5):533-41. PMID: 26097886; PMCID: PMC4468339.
      Citations: 16     
    41. Ling H, Pickard K, Ivan C, Isella C, Ikuo M, Mitter R, Spizzo R, Bullock M, Braicu C, Pileczki V, Vincent K, Pichler M, Stiegelbauer V, Hoefler G, Almeida MI, Hsiao A, Zhang X, Primrose J, Packham G, Liu K, Bojja K, Xiao L, Rossi S, Song JH, Vannini I, Fanini F, Kopetz S, Zweidler-McKay P, Wang X, Ionescu C, Irimie A, Fabbri M, Lanza G, Hamilton SR, Berindan-Neagoe I, Medico E, Mirnezami A, Calin GA, Nicoloso MS, Gaf? R. The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis. Gut. 2016 06; 65(6):977-989. PMID: 25804630; PMCID: PMC4581915.
      Citations: 74     Fields:    Translation:HumansAnimals
    42. Stoffel EM, Mangu PB, Gruber SB, Hamilton SR, Kalady MF, Lau MW, Lu KH, Roach N, Limburg PJ, American Society of Clinical Oncology, European Society of Clinical Oncology. Hereditary colorectal cancer syndromes: American Society of Clinical Oncology Clinical Practice Guideline endorsement of the familial risk-colorectal cancer: European Society for Medical Oncology Clinical Practice Guidelines. J Clin Oncol. 2015 Jan 10; 33(2):209-17. PMID: 25452455; PMCID: PMC5321096.
      Citations: 100     Fields:    Translation:HumansCellsPHPublic Health
    43. de Gramont A, Watson S, Ellis LM, Tabernero J, de Gramont A, Hamilton SR, Rod?n J. Pragmatic issues in biomarker evaluation for targeted therapies in cancer. Nat Rev Clin Oncol. 2015 Apr; 12(4):197-212. PMID: 25421275.
      Citations: 62     Fields:    Translation:Humans
    44. Bartley AN, Hamilton SR. Select biomarkers for tumors of the gastrointestinal tract: present and future. Arch Pathol Lab Med. 2015 Apr; 139(4):457-68. PMID: 25333834.
      Citations: 3     Fields:    Translation:Humans
    45. Bartley AN, Christ J, Fitzgibbons PL, Hamilton SR, Kakar S, Shah MA, Tang LH, Troxell ML, Members of the Cancer Biomarker Reporting Committee, College of American Pathologists. Template for Reporting Results of HER2 (ERBB2) Biomarker Testing of Specimens From Patients With Adenocarcinoma of the Stomach or Esophagogastric Junction. Arch Pathol Lab Med. 2015 May; 139(5):618-20. PMID: 25275813.
      Citations: 10     Fields:    Translation:Humans
    46. Jardim DL, de Melo Gagliato D, Falchook GS, Janku F, Zinner R, Wheler JJ, Subbiah V, Piha-Paul SA, Fu S, Murphy MB, Ajani J, Tang C, Hess K, Hamilton SR, Roy-Chowdhuri S, Kurzrock R, Meric-Bernstam F, Hong DS. MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit. Oncotarget. 2014 Apr 15; 5(7):1837-45. PMID: 24742823; PMCID: PMC4039117.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    47. Middleton LP, Feeley TW, Albright HW, Walters R, Hamilton SH. Second-opinion pathologic review is a patient safety mechanism that helps reduce error and decrease waste. J Oncol Pract. 2014 Jul; 10(4):275-80. PMID: 24695900.
      Citations: 7     Fields:    Translation:Humans
    48. Parkinson DR, McCormack RT, Keating SM, Gutman SI, Hamilton SR, Mansfield EA, Piper MA, Deverka P, Frueh FW, Jessup JM, McShane LM, Tunis SR, Sigman CC, Kelloff GJ. Evidence of clinical utility: an unmet need in molecular diagnostics for patients with cancer. Clin Cancer Res. 2014 Mar 15; 20(6):1428-44. PMID: 24634466.
      Citations: 42     Fields:    Translation:HumansPHPublic Health
    49. Cancer Genome Atlas Research Network, Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet. 2013 Oct; 45(10):1113-20. PMID: 24071849; PMCID: PMC3919969.
      Citations: 2555     Fields:    Translation:Humans
    50. Othman ML, Taggart MW, Hamilton SR, Curley SA, Rashid A, Abraham SC, Estrella JS. Intrabiliary growth of liver metastases: clinicopathologic features, prevalence, and outcome. Am J Surg Pathol. 2013 Oct; 37(10):1571-9. PMID: 23797727; PMCID: PMC3789528.
      Citations: 17     Fields:    Translation:Humans
    51. Bartley AN, Parikh N, Hsu CH, Roe DJ, Buckmeier JA, Corley L, Phipps RA, Gallick G, Lance P, Thompson PA, Hamilton SR. Colorectal adenoma stem-like cell populations: associations with adenoma characteristics and metachronous colorectal neoplasia. Cancer Prev Res (Phila). 2013 Nov; 6(11):1162-70. PMID: 24008128; PMCID: PMC4079278.
      Citations: 7     Fields:    Translation:HumansCells
    52. Andre T, Grothey A, Yothers G, Hamilton SR, Bot BM, Haller DG, Van Cutsem E, Twelves C, Benedetti JK, O'Connell MJ, Sargent DJ, Shi Q. Comparison of outcomes after fluorouracil-based adjuvant therapy for stages II and III colon cancer between 1978 to 1995 and 1996 to 2007: evidence of stage migration from the ACCENT database. J Clin Oncol. 2013 Oct 10; 31(29):3656-63. PMID: 23980089; PMCID: PMC3804289.
      Citations: 31     Fields:    Translation:Humans
    53. Bartley AN, Hamilton SR, Alsabeh R, Ambinder EP, Berman M, Collins E, Fitzgibbons PL, Gress DM, Nowak JA, Samowitz WS, Zafar SY, Members of the Cancer Biomarker Reporting Workgroup, College of American Pathologists. Template for reporting results of biomarker testing of specimens from patients with carcinoma of the colon and rectum. Arch Pathol Lab Med. 2014 Feb; 138(2):166-70. PMID: 23808403.
      Citations: 11     Fields:    Translation:HumansCells
    54. Ling H, Spizzo R, Atlasi Y, Nicoloso M, Shimizu M, Redis RS, Nishida N, Song J, Guo Z, Ivan C, Barbarotto E, De Vries I, Zhang X, Ferracin M, Churchman M, van Galen JF, Beverloo BH, Shariati M, Haderk F, Estecio MR, Garcia-Manero G, Patijn GA, Gotley DC, Bhardwaj V, Shureiqi I, Sen S, Multani AS, Welsh J, Yamamoto K, Taniguchi I, Song MA, Gallinger S, Casey G, Thibodeau SN, Tiirikainen M, Mani SA, Zhang W, Davuluri RV, Mimori K, Mori M, Sieuwerts AM, Martens JW, Tomlinson I, Negrini M, Berindan-Neagoe I, Foekens JA, Hamilton SR, Lanza G, Kopetz S, Fodde R, Calin GA, Gaf? R, Le Marchand L. CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res. 2013 Sep; 23(9):1446-61. PMID: 23796952; PMCID: PMC3759721.
      Citations: 314     Fields:    Translation:HumansAnimalsCells
    55. Overman MJ, Zhang J, Kopetz S, Davies M, Jiang ZQ, Zhi-Qin J, Stemke-Hale K, Pilarsky C, Hamilton S, Hwang R, Abbruzzese JL, Varadhachary G, Broom B, Wang H, R?mmele P, Gr?tzmann R. Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome. PLoS One. 2013; 8(6):e65144. PMID: 23776447; PMCID: PMC3679143.
      Citations: 19     Fields:    Translation:Humans
    56. Donehower LA, Creighton CJ, Schultz N, Shinbrot E, Chang K, Gunaratne PH, Muzny D, Sander C, Hamilton SR, Gibbs RA, Wheeler D. MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes. J Pathol. 2013 Jan; 229(1):99-110. PMID: 22899370; PMCID: PMC3926301.
      Citations: 40     Fields:    Translation:HumansCells
    57. Yang P, Cartwright C, Efuet E, Hamilton SR, Wistuba II, Menter D, Addington C, Shureiqi I, Newman RA. Cellular location and expression of Na+, K+ -ATPase a subunits affect the anti-proliferative activity of oleandrin. Mol Carcinog. 2014 Apr; 53(4):253-63. PMID: 23073998; PMCID: PMC4442617.
      Citations: 14     Fields:    Translation:HumansCells
    58. Thompson P, Roe DJ, Fales L, Buckmeier J, Wang F, Hamilton SR, Bhattacharyya A, Green S, Hsu CH, Chow HH, Ahnen DJ, Boland CR, Heigh RI, Fay DE, Martinez ME, Jacobs E, Ashbeck EL, Alberts DS, Lance P. Design and baseline characteristics of participants in a phase III randomized trial of celecoxib and selenium for colorectal adenoma prevention. Cancer Prev Res (Phila). 2012 Dec; 5(12):1381-93. PMID: 23060037; PMCID: PMC3518663.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    59. Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature. 2012 Jul 18; 487(7407):330-7. PMID: 22810696; PMCID: PMC3401966.
      Citations: 3605     Fields:    Translation:HumansCells
    60. Hamilton SR. Molecular pathology. Mol Oncol. 2012 Apr; 6(2):177-81. PMID: 22516585; PMCID: PMC5528368.
      Citations: 7     Fields:    Translation:Humans
    61. Konishi K, Watanabe Y, Shen L, Guo Y, Castoro RJ, Kondo K, Chung W, Ahmed S, Jelinek J, Boumber YA, Estecio MR, Maegawa S, Kondo Y, Itoh F, Imawari M, Hamilton SR, Issa JP. DNA methylation profiles of primary colorectal carcinoma and matched liver metastasis. PLoS One. 2011; 6(11):e27889. PMID: 22132162; PMCID: PMC3221680.
      Citations: 15     Fields:    Translation:HumansCells
    62. Bartley AN, Yao H, Barkoh BA, Ivan C, Mishra BM, Rashid A, Calin GA, Luthra R, Hamilton SR. Complex patterns of altered MicroRNA expression during the adenoma-adenocarcinoma sequence for microsatellite-stable colorectal cancer. Clin Cancer Res. 2011 Dec 01; 17(23):7283-93. PMID: 21948089; PMCID: PMC3544185.
      Citations: 42     Fields:    Translation:HumansCells
    63. Sun Y, Yokoi K, Li H, Gao J, Hu L, Liu B, Chen K, Hamilton SR, Fan D, Sun B, Zhang W. NGAL expression is elevated in both colorectal adenoma-carcinoma sequence and cancer progression and enhances tumorigenesis in xenograft mouse models. Clin Cancer Res. 2011 Jul 01; 17(13):4331-40. PMID: 21622717; PMCID: PMC3575684.
      Citations: 25     Fields:    Translation:HumansAnimals
    64. Cheng H, Zhang L, Cogdell DE, Zheng H, Schetter AJ, Nykter M, Harris CC, Chen K, Hamilton SR, Zhang W. Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis. PLoS One. 2011 Mar 17; 6(3):e17745. PMID: 21445232; PMCID: PMC3060165.
      Citations: 202     Fields:    Translation:Humans
    65. Hayashi Y, Molina JR, Hamilton SR, Georgescu MM. NHERF1/EBP50 is a new marker in colorectal cancer. Neoplasia. 2010 Dec; 12(12):1013-22. PMID: 21170265; PMCID: PMC3003136.
      Citations: 52     Fields:    Translation:HumansCells
    66. De Jesus-Monge WE, Gonzalez-Keelan C, Zhao R, Hamilton SR, Rodriguez-Bigas M, Cruz-Correa M. Mismatch repair protein expression and colorectal cancer in Hispanics from Puerto Rico. Fam Cancer. 2010 Jun; 9(2):155-66. PMID: 20012372; PMCID: PMC2873132.
      Citations: 18     Fields:    Translation:HumansCells
    67. Earle JS, Luthra R, Romans A, Abraham R, Ensor J, Yao H, Hamilton SR. Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma. J Mol Diagn. 2010 Jul; 12(4):433-40. PMID: 20413677; PMCID: PMC2893627.
      Citations: 75     Fields:    Translation:Humans
    68. International Cancer Genome Consortium, Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, Kerr D, Klatt P, Kolar P, Kusada J, Lane DP, Laplace F, Youyong L, Nettekoven G, Ozenberger B, Peterson J, Rao TS, Remacle J, Schafer AJ, Shibata T, Stratton MR, Vockley JG, Watanabe K, Yang H, Yuen MM, Knoppers BM, Bobrow M, Cambon-Thomsen A, Dressler LG, Dyke SO, Joly Y, Kato K, Kennedy KL, Parker MJ, Rial-Sebbag E, Romeo-Casabona CM, Shaw KM, Wallace S, Wiesner GL, Zeps N, Lichter P, Biankin AV, Chabannon C, Chin L, de Alava E, Ferguson ML, Geary P, Hayes DN, Johns AL, Kasprzyk A, Nakagawa H, Penny R, Piris MA, Sarin R, Scarpa A, van de Vijver M, Futreal PA, Aburatani H, Botwell DD, Campbell PJ, Estivill X, Grimmond SM, Gut I, Hirst M, Majumder P, Marra M, McPherson JD, Ning Z, Puente XS, Ruan Y, Stunnenberg HG, Swerdlow H, Velculescu VE, Wilson RK, Xue HH, Yang L, Spellman PT, Bader GD, Boutros PC, Flicek P, Getz G, Guo G, Haussler D, Heath S, Hubbard TJ, Jiang T, Jones SM, Li Q, Luo R, Muthuswamy L, Ouellette BF, Pearson JV, Quesada V, Raphael BJ, Sander C, Speed TP, Stein LD, Stuart JM, Teague JW, Totoki Y, Tsunoda T, Valencia A, Wheeler DA, Wu H, Zhao S, Zhou G, Lathrop M, Thomas G, Yoshida T, Axton M, Gunter C, Miller LJ, Zhang J, Haider SA, Wang J, Yung CK, Cros A, Cross A, Liang Y, Gnaneshan S, Guberman J, Hsu J, Chalmers DR, Hasel KW, Kaan TS, Lowrance WW, Masui T, Rodriguez LL, Vergely C, Bowtell DD, Cloonan N, deFazio A, Eshleman JR, Etemadmoghadam D, Gardiner BB, Gardiner BA, Kench JG, Sutherland RL, Tempero MA, Waddell NJ, Wilson PJ, Gallinger S, Tsao MS, Shaw PA, Petersen GM, Mukhopadhyay D, DePinho RA, Thayer S, Shazand K, Beck T, Sam M, Timms L, Ballin V, Lu Y, Ji J, Zhang X, Chen F, Hu X, Yang Q, Tian G, Zhang L, Xing X, Li X, Zhu Z, Yu Y, Yu J, Brennan P, Holcatova I, Zaridze D, Brazma A, Egevard L, Prokhortchouk E, Banks RE, Viksna J, Ponten F, Skryabin K, Birney E, Borg A, Caldas C, Foekens JA, Martin S, Reis-Filho JS, Richardson AL, Sotiriou C, Thoms G, van't Veer L, Birnbaum D, Boucher P, Boyault S, Masson-Jacquemier JD, Pivot X, Vincent-Salomon A, Tabone E, Theillet C, Treilleux I, Bioulac-Sage P, Decaens T, Franco D, Gut M, Samuel D, Zucman-Rossi J, Eils R, Brors B, Korbel JO, Korshunov A, Landgraf P, Lehrach H, Pfister S, Radlwimmer B, Reifenberger G, Taylor MD, von Kalle C, Majumder PP, Pederzoli P, Lawlor RA, Delledonne M, Bardelli A, Gress T, Klimstra D, Zamboni G, Nakamura Y, Miyano S, Fujimoto A, Campo E, Montserrat E, Jares P, Himmelbauer H, Himmelbaue H, Bea S, Aparicio S, Easton DF, Collins FS, Compton CC, Lander ES, Burke W, Green AR, Hamilton SR, Kallioniemi OP, Ley TJ, Liu ET, Wainwright BJ, Bernab? RR, Nicol?s P, Cl?ment B, Degos F, Bay?s M, L?pez-Ot?n C, Guig? R, L?pez-Bigas N, Tost J, Uhl?n M, B?rresen-Dale AL, Blanche H, Pauport? I, de Sanjos? S, Gonz?lez-D?az M. International network of cancer genome projects. Nature. 2010 Apr 15; 464(7291):993-8. PMID: 20393554; PMCID: PMC2902243.
      Citations: 1005     Fields:    Translation:HumansCells
    69. Coolbaugh-Murphy MI, Xu JP, Ramagli LS, Ramagli BC, Brown BW, Lynch PM, Hamilton SR, Frazier ML, Siciliano MJ. Microsatellite instability in the peripheral blood leukocytes of HNPCC patients. Hum Mutat. 2010 Mar; 31(3):317-24. PMID: 20052760; PMCID: PMC3544178.
      Citations: 16     Fields:    Translation:HumansCells
    70. Bartley AN, Thompson PA, Buckmeier JA, Kepler CY, Hsu CH, Snyder MS, Lance P, Bhattacharyya A, Hamilton SR. Expression of gastric pyloric mucin, MUC6, in colorectal serrated polyps. Mod Pathol. 2010 Feb; 23(2):169-76. PMID: 19855374; PMCID: PMC2818151.
      Citations: 13     Fields:    Translation:Humans
    71. Konishi K, Shen L, Jelinek J, Watanabe Y, Ahmed S, Kaneko K, Kogo M, Takano T, Imawari M, Hamilton SR, Issa JP. Concordant DNA methylation in synchronous colorectal carcinomas. Cancer Prev Res (Phila). 2009 Sep; 2(9):814-22. PMID: 19737982; PMCID: PMC3544187.
      Citations: 24     Fields:    Translation:HumansCells
    72. Rossi S, Kopetz S, Davuluri R, Hamilton SR, Calin GA. MicroRNAs, ultraconserved genes and colorectal cancers. Int J Biochem Cell Biol. 2010 Aug; 42(8):1291-7. PMID: 19497386.
      Citations: 22     Fields:    Translation:HumansCells
    73. Crane CH, Eng C, Feig BW, Das P, Skibber JM, Chang GJ, Wolff RA, Krishnan S, Hamilton S, Janjan NA, Maru DM, Ellis LM, Rodriguez-Bigas MA. Phase II trial of neoadjuvant bevacizumab, capecitabine, and radiotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 2010 Mar 01; 76(3):824-30. PMID: 19464823.
      Citations: 71     Fields:    Translation:HumansCTClinical Trials
    74. Hu L, Hittelman W, Lu T, Ji P, Arlinghaus R, Shmulevich I, Hamilton SR, Zhang W. NGAL decreases E-cadherin-mediated cell-cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells. Lab Invest. 2009 May; 89(5):531-48. PMID: 19308044; PMCID: PMC7770608.
      Citations: 53     Fields:    Translation:HumansCells
    75. Allegra CJ, Jessup JM, Somerfield MR, Hamilton SR, Hammond EH, Hayes DF, McAllister PK, Morton RF, Schilsky RL. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol. 2009 Apr 20; 27(12):2091-6. PMID: 19188670.
      Citations: 473     Fields:    Translation:Humans
    76. Wang H, Song X, Logsdon C, Zhou G, Evans DB, Abbruzzese JL, Hamilton SR, Tan TH, Wang H. Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer. Cancer Res. 2009 Feb 01; 69(3):1063-70. PMID: 19141650; PMCID: PMC4403239.
      Citations: 13     Fields:    Translation:HumansCells
    77. Liang JJ, Wang H, Rashid A, Tan TH, Hwang RF, Hamilton SR, Abbruzzese JL, Evans DB, Wang H. Expression of MAP4K4 is associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma. Clin Cancer Res. 2008 Nov 01; 14(21):7043-9. PMID: 18981001.
      Citations: 48     Fields:    Translation:Humans
    78. Sanchez AA, Wu TT, Prieto VG, Rashid A, Hamilton SR, Wang H. Comparison of primary and metastatic malignant melanoma of the esophagus: clinicopathologic review of 10 cases. Arch Pathol Lab Med. 2008 Oct; 132(10):1623-9. PMID: 18834221.
      Citations: 24     Fields:    Translation:Humans
    79. Yang L, Hamilton SR, Sood A, Kuwai T, Ellis L, Sanguino A, Lopez-Berestein G, Boyd DD. The previously undescribed ZKSCAN3 (ZNF306) is a novel "driver" of colorectal cancer progression. Cancer Res. 2008 Jun 01; 68(11):4321-30. PMID: 18519692.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    80. Suehiro Y, Wong CW, Chirieac LR, Kondo Y, Shen L, Webb CR, Chan YW, Chan AS, Chan TL, Wu TT, Rashid A, Hamanaka Y, Hinoda Y, Shannon RL, Wang X, Morris J, Issa JP, Yuen ST, Leung SY, Hamilton SR. Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma. Clin Cancer Res. 2008 May 01; 14(9):2560-9. PMID: 18451217; PMCID: PMC3544184.
      Citations: 52     Fields:    Translation:HumansCells
    81. Hamilton SR. Targeted therapy of cancer: new roles for pathologists in colorectal cancer. Mod Pathol. 2008 May; 21 Suppl 2:S23-30. PMID: 18437170.
      Citations: 16     Fields:    Translation:Humans
    82. Kuwai T, Nakamura T, Kim SJ, Sasaki T, Kitadai Y, Langley RR, Fan D, Hamilton SR, Fidler IJ. Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. Am J Pathol. 2008 Feb; 172(2):358-66. PMID: 18202197; PMCID: PMC2312354.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    83. Thomas MB, Tetzlaff E, Lozano R, Samp L, Butler CE, Gannon C, Hamilton S, Vauthey JN, Abdalla E. Curing hepatocellular carcinomatosis with biologic therapy and surgery: achieving the impossible? J Surg Oncol. 2008 Jan 01; 97(1):82-4. PMID: 17918216.
      Citations: 1     Fields:    Translation:Humans
    84. Shen L, Toyota M, Kondo Y, Lin E, Zhang L, Guo Y, Hernandez NS, Chen X, Ahmed S, Konishi K, Hamilton SR, Issa JP. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18654-9. PMID: 18003927; PMCID: PMC2141832.
      Citations: 229     Fields:    Translation:HumansCells
    85. Shen L, Catalano PJ, Benson AB, O'Dwyer P, Hamilton SR, Issa JP. Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy. Clin Cancer Res. 2007 Oct 15; 13(20):6093-8. PMID: 17947473; PMCID: PMC3575642.
      Citations: 79     Fields:    Translation:HumansCells
    86. Jiang R, Choi W, Khan A, Hess K, Gerner EW, Casero RA, Yung WK, Hamilton SR, Zhang W. Activation of polyamine catabolism by N1,N11-diethylnorspermine leads to cell death in glioblastoma. Int J Oncol. 2007 Aug; 31(2):431-40. PMID: 17611701.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    87. Jiang R, Choi W, Hu L, Gerner EW, Hamilton SR, Zhang W. Activation of polyamine catabolism by N1, N11-diethylnorspermine alters the cellular localization of mTOR and downregulates mTOR protein level in glioblastoma cells. Cancer Biol Ther. 2007 Oct; 6(10):1644-8. PMID: 17921698.
      Citations: 7     Fields:    Translation:HumansCells
    88. Mendes KN, Nicorici D, Cogdell D, Tabus I, Yli-Harja O, Guerra R, Hamilton SR, Zhang W. Analysis of signaling pathways in 90 cancer cell lines by protein lysate array. J Proteome Res. 2007 Jul; 6(7):2753-67. PMID: 17564428.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    89. Nagano Y, Kim DH, Zhang L, White JA, Yao JC, Hamilton SR, Rashid A. Allelic alterations in pancreatic endocrine tumors identified by genome-wide single nucleotide polymorphism analysis. Endocr Relat Cancer. 2007 Jun; 14(2):483-92. PMID: 17639061.
      Citations: 14     Fields:    Translation:HumansCells
    90. Mori-Akiyama Y, van den Born M, van Es JH, Hamilton SR, Adams HP, Zhang J, Clevers H, de Crombrugghe B. SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. Gastroenterology. 2007 Aug; 133(2):539-46. PMID: 17681175.
      Citations: 170     Fields:    Translation:AnimalsCells
    91. Camp ER, Yang A, Gray MJ, Fan F, Hamilton SR, Evans DB, Hooper AT, Pereira DS, Hicklin DJ, Ellis LM. Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target. Cancer. 2007 Mar 15; 109(6):1030-9. PMID: 17311308.
      Citations: 45     Fields:    Translation:HumansCells
    92. Cho SD, Yoon K, Chintharlapalli S, Abdelrahim M, Lei P, Hamilton S, Khan S, Ramaiah SK, Safe S. Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways. Cancer Res. 2007 Jan 15; 67(2):674-83. PMID: 17234778.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    93. Kitadai Y, Sasaki T, Kuwai T, Nakamura T, Bucana CD, Hamilton SR, Fidler IJ. Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential. Int J Cancer. 2006 Dec 01; 119(11):2567-74. PMID: 16988946.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    94. Choi W, Cogdell D, Feng Y, Hamilton SR, Zhang W. Transcriptional activation of the carboxylesterase 2 gene by the p53 pathway. Cancer Biol Ther. 2006 Nov; 5(11):1450-6. PMID: 16963839.
      Citations: 9     Fields:    Translation:HumansCells
    95. Krishnan S, Janjan NA, Skibber JM, Rodriguez-Bigas MA, Wolff RA, Das P, Delclos ME, Chang GJ, Hoff PM, Eng C, Brown TD, Crane CH, Feig BW, Morris J, Vadhan-Raj S, Hamilton SR, Lin EH. Phase II study of capecitabine (Xeloda) and concomitant boost radiotherapy in patients with locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 2006 Nov 01; 66(3):762-71. PMID: 17011451.
      Citations: 44     Fields:    Translation:HumansCTClinical Trials
    96. Locker GY, Hamilton S, Harris J, Jessup JM, Kemeny N, Macdonald JS, Somerfield MR, Hayes DF, Bast RC, ASCO. ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. J Clin Oncol. 2006 Nov 20; 24(33):5313-27. PMID: 17060676.
      Citations: 537     Fields:    Translation:HumansPHPublic Health
    97. Wang KL, Yang Q, Cleary KR, Swisher SG, Correa AM, Komaki R, Ajani JA, Rashid A, Hamilton SR, Wu TT. The significance of neuroendocrine differentiation in adenocarcinoma of the esophagus and esophagogastric junction after preoperative chemoradiation. Cancer. 2006 Oct 01; 107(7):1467-74. PMID: 16955509.
      Citations: 8     Fields:    Translation:Humans
    98. Soliman AS, Bondy M, Webb CR, Schottenfeld D, Bonner J, El-Ghawalby N, Soultan A, Abdel-Wahab M, Fathy O, Ebidi G, Zhang Q, Greenson JK, Abbruzzese JL, Hamilton SR. Differing molecular pathology of pancreatic adenocarcinoma in Egyptian and United States patients. Int J Cancer. 2006 Sep 15; 119(6):1455-61. PMID: 16619252.
      Citations: 6     Fields:    Translation:Humans
    99. Choi W, Proctor L, Xia Q, Feng Y, Gerner EW, Chiao PJ, Hamilton SR, Zhang W. Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase. Mol Carcinog. 2006 Sep; 45(9):685-93. PMID: 16637064.
      Citations: 4     Fields:    Translation:HumansCells
    100. Wang KL, Wu TT, Resetkova E, Wang H, Correa AM, Hofstetter WL, Swisher SG, Ajani JA, Rashid A, Hamilton SR, Albarracin CT. Expression of annexin A1 in esophageal and esophagogastric junction adenocarcinomas: association with poor outcome. Clin Cancer Res. 2006 Aug 01; 12(15):4598-604. PMID: 16899607.
      Citations: 44     Fields:    Translation:Humans
    101. Levin B, Barthel JS, Burt RW, David DS, Ford JM, Giardiello FM, Gruber SB, Halverson AL, Hamilton S, Kohlmann W, Ludwig KA, Lynch PM, Marino C, Martin EW, Mayer RJ, Pasche B, Pirruccello SJ, Rajput A, Rao MS, Shike M, Steinbach G, Terdiman JP, Weinberg D, Winawer SJ. Colorectal Cancer Screening Clinical Practice Guidelines. J Natl Compr Canc Netw. 2006 Apr; 4(4):384-420. PMID: 16569391.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    102. Gu Y, Swisher SG, Ajani JA, Correa AM, Hofstetter WL, Liao Z, Komaki RR, Rashid A, Hamilton SR, Wu TT. The number of lymph nodes with metastasis predicts survival in patients with esophageal or esophagogastric junction adenocarcinoma who receive preoperative chemoradiation. Cancer. 2006 Mar 01; 106(5):1017-25. PMID: 16456809.
      Citations: 32     Fields:    Translation:HumansCTClinical Trials
    103. Kuo MT, Wei Y, Yang X, Tatebe S, Liu J, Troncoso P, Sahin A, Ro JY, Hamilton SR, Savaraj N. Association of fragile site-associated (FSA) gene expression with epithelial differentiation and tumor development. Biochem Biophys Res Commun. 2006 Feb 17; 340(3):887-93. PMID: 16386706.
      Citations: 2     Fields:    Translation:AnimalsCells
    104. Shureiqi I, Wu Y, Chen D, Yang XL, Guan B, Morris JS, Yang P, Newman RA, Broaddus R, Hamilton SR, Lynch P, Levin B, Fischer SM, Lippman SM. The critical role of 15-lipoxygenase-1 in colorectal epithelial cell terminal differentiation and tumorigenesis. Cancer Res. 2005 Dec 15; 65(24):11486-92. PMID: 16357157; PMCID: PMC1564070.
      Citations: 39     Fields:    Translation:HumansCells
    105. Liu L, Broaddus RR, Yao JC, Xie S, White JA, Wu TT, Hamilton SR, Rashid A. Epigenetic alterations in neuroendocrine tumors: methylation of RAS-association domain family 1, isoform A and p16 genes are associated with metastasis. Mod Pathol. 2005 Dec; 18(12):1632-40. PMID: 16258509.
      Citations: 35     Fields:    Translation:HumansCells
    106. Chan AO, Soliman AS, Zhang Q, Rashid A, Bedeir A, Houlihan PS, Mokhtar N, Al-Masri N, Ozbek U, Yaghan R, Kandilci A, Omar S, Kapran Y, Dizdaroglu F, Bondy ML, Amos CI, Issa JP, Levin B, Hamilton SR. Differing DNA methylation patterns and gene mutation frequencies in colorectal carcinomas from Middle Eastern countries. Clin Cancer Res. 2005 Dec 01; 11(23):8281-7. PMID: 16322286.
      Citations: 20     Fields:    Translation:HumansCells
    107. Yokoi K, Shih LC, Kobayashi R, Koomen J, Hawke D, Li D, Hamilton SR, Abbruzzese JL, Coombes KR, Fidler IJ. Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer. Int J Oncol. 2005 Nov; 27(5):1361-9. PMID: 16211233.
      Citations: 24     Fields:    Translation:HumansAnimals
    108. Lin Q, Lai R, Chirieac LR, Li C, Thomazy VA, Grammatikakis I, Rassidakis GZ, Zhang W, Fujio Y, Kunisada K, Hamilton SR, Amin HM. Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells. Am J Pathol. 2005 Oct; 167(4):969-80. PMID: 16192633; PMCID: PMC1603671.
      Citations: 90     Fields:    Translation:HumansCells
    109. Shen L, Kondo Y, Rosner GL, Xiao L, Hernandez NS, Vilaythong J, Houlihan PS, Krouse RS, Prasad AR, Einspahr JG, Buckmeier J, Alberts DS, Hamilton SR, Issa JP. MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst. 2005 Sep 21; 97(18):1330-8. PMID: 16174854.
      Citations: 211     Fields:    Translation:HumansCells
    110. Hu J, Kapoor M, Zhang W, Hamilton SR, Coombes KR. Analysis of dose-response effects on gene expression data with comparison of two microarray platforms. Bioinformatics. 2005 Sep 01; 21(17):3524-9. PMID: 16081476.
      Citations: 9     Fields:    Translation:HumansCells
    111. Wang GG, Yao JC, Worah S, White JA, Luna R, Wu TT, Hamilton SR, Rashid A. Comparison of genetic alterations in neuroendocrine tumors: frequent loss of chromosome 18 in ileal carcinoid tumors. Mod Pathol. 2005 Aug; 18(8):1079-87. PMID: 15920555.
      Citations: 19     Fields:    Translation:HumansCells
    112. Liu L, Hofstetter WL, Rashid A, Swisher SG, Correa AM, Ajani JA, Hamilton SR, Wu TT. Significance of the depth of tumor invasion and lymph node metastasis in superficially invasive (T1) esophageal adenocarcinoma. Am J Surg Pathol. 2005 Aug; 29(8):1079-85. PMID: 16006804.
      Citations: 55     Fields:    Translation:Humans
    113. Yokoi K, Kim SJ, Thaker P, Yazici S, Nam DH, He J, Sasaki T, Chiao PJ, Sclabas GM, Abbruzzese JL, Hamilton SR, Fidler IJ. Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice. Neoplasia. 2005 Jul; 7(7):696-704. PMID: 16026649; PMCID: PMC1501424.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    114. Yokoi K, Thaker PH, Yazici S, Rebhun RR, Nam DH, He J, Kim SJ, Abbruzzese JL, Hamilton SR, Fidler IJ. Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. Cancer Res. 2005 May 01; 65(9):3716-25. PMID: 15867367.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    115. Chirieac LR, Swisher SG, Ajani JA, Komaki RR, Correa AM, Morris JS, Roth JA, Rashid A, Hamilton SR, Wu TT. Posttherapy pathologic stage predicts survival in patients with esophageal carcinoma receiving preoperative chemoradiation. Cancer. 2005 Apr 01; 103(7):1347-55. PMID: 15719440.
      Citations: 137     Fields:    Translation:Humans
    116. Beach R, Chan AO, Wu TT, White JA, Morris JS, Lunagomez S, Broaddus RR, Issa JP, Hamilton SR, Rashid A. BRAF mutations in aberrant crypt foci and hyperplastic polyposis. Am J Pathol. 2005 Apr; 166(4):1069-75. PMID: 15793287; PMCID: PMC1602378.
      Citations: 29     Fields:    Translation:HumansCells
    117. Giardiello FM, Hylind LM, Trimbath JD, Hamilton SR, Romans KE, Cruz-Correa M, Corretti MC, Offerhaus GJ, Yang VW. Oral contraceptives and polyp regression in familial adenomatous polyposis. Gastroenterology. 2005 Apr; 128(4):1077-80. PMID: 15825088.
      Citations: 8     Fields:    Translation:Humans
    118. Chirieac LR, Shen L, Catalano PJ, Issa JP, Hamilton SR. Phenotype of microsatellite-stable colorectal carcinomas with CpG island methylation. Am J Surg Pathol. 2005 Apr; 29(4):429-36. PMID: 15767794.
      Citations: 18     Fields:    Translation:HumansCells
    119. Chirieac LR, Swisher SG, Correa AM, Ajani JA, Komaki RR, Rashid A, Hamilton SR, Wu TT. Signet-ring cell or mucinous histology after preoperative chemoradiation and survival in patients with esophageal or esophagogastric junction adenocarcinoma. Clin Cancer Res. 2005 Mar 15; 11(6):2229-36. PMID: 15788671.
      Citations: 26     Fields:    Translation:Humans
    120. Peters BA, Diaz LA, Polyak K, Meszler L, Romans K, Guinan EC, Antin JH, Myerson D, Hamilton SR, Vogelstein B, Kinzler KW, Lengauer C. Contribution of bone marrow-derived endothelial cells to human tumor vasculature. Nat Med. 2005 Mar; 11(3):261-2. PMID: 15723071.
      Citations: 153     Fields:    Translation:HumansCells
    121. An C, Choi IS, Yao JC, Worah S, Xie K, Mansfield PF, Ajani JA, Rashid A, Hamilton SR, Wu TT. Prognostic significance of CpG island methylator phenotype and microsatellite instability in gastric carcinoma. Clin Cancer Res. 2005 Jan 15; 11(2 Pt 1):656-63. PMID: 15701853.
      Citations: 66     Fields:    Translation:HumansCells
    122. Mircean C, Shmulevich I, Cogdell D, Choi W, Jia Y, Tabus I, Hamilton SR, Zhang W. Robust estimation of protein expression ratios with lysate microarray technology. Bioinformatics. 2005 May 01; 21(9):1935-42. PMID: 15647295.
      Citations: 12     Fields:    Translation:HumansCells
    123. Niemisto A, Shmulevich I, Yli-Harja O, Chirieac LR, Hamilton SR. Automated quantification of lymph node size and number in surgical specimens of stage II colorectal cancer. Conf Proc IEEE Eng Med Biol Soc. 2005; 2005:6313-6. PMID: 17281711.
      Citations: 1     Fields:    
    124. Choi W, Gerner EW, Ramdas L, Dupart J, Carew J, Proctor L, Huang P, Zhang W, Hamilton SR. Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells. J Biol Chem. 2005 Feb 04; 280(5):3295-304. PMID: 15546879; PMCID: PMC3584635.
      Citations: 15     Fields:    Translation:HumansCells
    125. Persad R, Liu C, Wu TT, Houlihan PS, Hamilton SR, Diehl AM, Rashid A. Overexpression of caspase-3 in hepatocellular carcinomas. Mod Pathol. 2004 Jul; 17(7):861-7. PMID: 15098015.
      Citations: 38     Fields:    Translation:HumansCells
    126. Ramdas L, Cogdell DE, Jia JY, Taylor EE, Dunmire VR, Hu L, Hamilton SR, Zhang W. Improving signal intensities for genes with low-expression on oligonucleotide microarrays. BMC Genomics. 2004 Jun 14; 5(1):35. PMID: 15196312; PMCID: PMC436055.
      Citations: 8     Fields:    Translation:HumansCells
    127. Lee JH, Park SJ, Abraham SC, Seo JS, Nam JH, Choi C, Juhng SW, Rashid A, Hamilton SR, Wu TT. Frequent CpG island methylation in precursor lesions and early gastric adenocarcinomas. Oncogene. 2004 Jun 03; 23(26):4646-54. PMID: 15064707.
      Citations: 41     Fields:    Translation:HumansCells
    128. McGregor DK, Wu TT, Rashid A, Luthra R, Hamilton SR. Reduced expression of cytokeratin 20 in colorectal carcinomas with high levels of microsatellite instability. Am J Surg Pathol. 2004 Jun; 28(6):712-8. PMID: 15166663.
      Citations: 31     Fields:    Translation:HumansCells
    129. Umar A, Boland CR, Terdiman JP, Syngal S, de la Chapelle A, Fishel R, Lindor NM, Burgart LJ, Hamelin R, Hamilton SR, Hiatt RA, Jass J, Lindblom A, Lynch HT, Ramsey SD, Rodriguez-Bigas MA, Vasen HF, Hawk ET, Barrett JC, Freedman AN, Srivastava S, R?schoff J, Peltomaki P. Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst. 2004 Feb 18; 96(4):261-8. PMID: 14970275; PMCID: PMC2933058.
      Citations: 1100     Fields:    Translation:HumansCells
    130. Giardiello FM, Casero RA, Hamilton SR, Hylind LM, Trimbath JD, Geiman DE, Judge KR, Hubbard W, Offerhaus GJ, Yang VW. Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis. Gastroenterology. 2004 Feb; 126(2):425-31. PMID: 14762779; PMCID: PMC2225536.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    131. Maru D, Wu TT, Canada A, Houlihan PS, Hamilton SR, Rashid A. Loss of chromosome 18q and DPC4 (Smad4) mutations in appendiceal adenocarcinomas. Oncogene. 2004 Jan 22; 23(3):859-64. PMID: 14647445.
      Citations: 8     Fields:    Translation:HumansCells
    132. Stancu M, Wu TT, Wallace C, Houlihan PS, Hamilton SR, Rashid A. Genetic alterations in goblet cell carcinoids of the vermiform appendix and comparison with gastrointestinal carcinoid tumors. Mod Pathol. 2003 Dec; 16(12):1189-98. PMID: 14681318.
      Citations: 32     Fields:    Translation:HumansCells
    133. Kim SG, Wu TT, Lee JH, Yun YK, Issa JP, Hamilton SR, Rashid A. Comparison of epigenetic and genetic alterations in mucinous cystic neoplasm and serous microcystic adenoma of pancreas. Mod Pathol. 2003 Nov; 16(11):1086-94. PMID: 14614047.
      Citations: 23     Fields:    Translation:HumansCells
    134. Zhang W, Ramdas L, Shen W, Song SW, Hu L, Hamilton SR. Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2. Cancer Biol Ther. 2003 Sep-Oct; 2(5):572-8. PMID: 14614330.
      Citations: 10     Fields:    Translation:HumansCells
    135. Ribic CM, Sargent DJ, Moore MJ, Thibodeau SN, French AJ, Goldberg RM, Hamilton SR, Laurent-Puig P, Gryfe R, Shepherd LE, Tu D, Redston M, Gallinger S. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med. 2003 Jul 17; 349(3):247-57. PMID: 12867608; PMCID: PMC3584639.
      Citations: 831     Fields:    Translation:HumansCellsCTClinical Trials
    136. Kim SG, Chan AO, Wu TT, Issa JP, Hamilton SR, Rashid A. Epigenetic and genetic alterations in duodenal carcinomas are distinct from biliary and ampullary carcinomas. Gastroenterology. 2003 May; 124(5):1300-10. PMID: 12730870.
      Citations: 12     Fields:    Translation:HumansCells
    137. Shmulevich I, Astola J, Cogdell D, Hamilton SR, Zhang W. Data extraction from composite oligonucleotide microarrays. Nucleic Acids Res. 2003 Apr 01; 31(7):e36. PMID: 12655024; PMCID: PMC152821.
      Citations: 2     Fields:    Translation:HumansCells
    138. Park SJ, Rashid A, Lee JH, Kim SG, Hamilton SR, Wu TT. Frequent CpG island methylation in serrated adenomas of the colorectum. Am J Pathol. 2003 Mar; 162(3):815-22. PMID: 12598316; PMCID: PMC1868094.
      Citations: 74     Fields:    Translation:HumansCells
    139. Shen L, Kondo Y, Hamilton SR, Rashid A, Issa JP. P14 methylation in human colon cancer is associated with microsatellite instability and wild-type p53. Gastroenterology. 2003 Mar; 124(3):626-33. PMID: 12612901.
      Citations: 30     Fields:    Translation:HumansCells
    140. Chan AO, Kim SG, Bedeir A, Issa JP, Hamilton SR, Rashid A. CpG island methylation in carcinoid and pancreatic endocrine tumors. Oncogene. 2003 Feb 13; 22(6):924-34. PMID: 12584572.
      Citations: 34     Fields:    Translation:HumansCells
    141. Furuta K, Yoshioka S, Okabe S, Ikeda M, Oginosawa M, Ikeda S, Nakayama Y, Kikuchi M, Hamilton SR. Expressions of two adenomatous polyposis coli and E-cadherin proteins on human colorectal cancers. Virchows Arch. 2003 Mar; 442(3):266-70. PMID: 12647217.
      Citations: 1     Fields:    Translation:Humans
    142. Kim S, Dougherty ER, Shmulevich I, Hess KR, Hamilton SR, Trent JM, Fuller GN, Zhang W. Identification of combination gene sets for glioma classification. Mol Cancer Ther. 2002 Nov; 1(13):1229-36. PMID: 12479704.
      Citations: 35     Fields:    Translation:Humans
    143. Abraham SC, Park SJ, Mugartegui L, Hamilton SR, Wu TT. Sporadic fundic gland polyps with epithelial dysplasia : evidence for preferential targeting for mutations in the adenomatous polyposis coli gene. Am J Pathol. 2002 Nov; 161(5):1735-42. PMID: 12414520; PMCID: PMC1850790.
      Citations: 17     Fields:    Translation:HumansCells
    144. Lee JH, Abraham SC, Kim HS, Nam JH, Choi C, Lee MC, Park CS, Juhng SW, Rashid A, Hamilton SR, Wu TT. Inverse relationship between APC gene mutation in gastric adenomas and development of adenocarcinoma. Am J Pathol. 2002 Aug; 161(2):611-8. PMID: 12163385; PMCID: PMC1850731.
      Citations: 47     Fields:    Translation:HumansCells
    145. Kabbani W, Houlihan PS, Luthra R, Hamilton SR, Rashid A. Mucinous and nonmucinous appendiceal adenocarcinomas: different clinicopathological features but similar genetic alterations. Mod Pathol. 2002 Jun; 15(6):599-605. PMID: 12065772.
      Citations: 35     Fields:    Translation:HumansCells
    146. Chan AO, Broaddus RR, Houlihan PS, Issa JP, Hamilton SR, Rashid A. CpG island methylation in aberrant crypt foci of the colorectum. Am J Pathol. 2002 May; 160(5):1823-30. PMID: 12000733; PMCID: PMC1850869.
      Citations: 83     Fields:    Translation:HumansCells
    147. Giardiello FM, Yang VW, Hylind LM, Krush AJ, Petersen GM, Trimbath JD, Piantadosi S, Garrett E, Geiman DE, Hubbard W, Offerhaus GJ, Hamilton SR. Primary chemoprevention of familial adenomatous polyposis with sulindac. N Engl J Med. 2002 Apr 04; 346(14):1054-9. PMID: 11932472; PMCID: PMC2225537.
      Citations: 111     Fields:    Translation:HumansCTClinical Trials
    148. Traverso G, Shuber A, Olsson L, Levin B, Johnson C, Hamilton SR, Boynton K, Kinzler KW, Vogelstein B. Detection of proximal colorectal cancers through analysis of faecal DNA. Lancet. 2002 Feb 02; 359(9304):403-4. PMID: 11844514.
      Citations: 24     Fields:    Translation:HumansCells
    149. Chan AO, Issa JP, Morris JS, Hamilton SR, Rashid A. Concordant CpG island methylation in hyperplastic polyposis. Am J Pathol. 2002 Feb; 160(2):529-36. PMID: 11839573; PMCID: PMC1850645.
      Citations: 49     Fields:    Translation:HumansCells
    150. Gillespie JW, Best CJ, Bichsel VE, Cole KA, Greenhut SF, Hewitt SM, Ahram M, Gathright YB, Merino MJ, Strausberg RL, Epstein JI, Hamilton SR, Gannot G, Baibakova GV, Calvert VS, Flaig MJ, Chuaqui RF, Herring JC, Pfeifer J, Petricoin EF, Linehan WM, Duray PH, Bova GS, Emmert-Buck MR. Evaluation of non-formalin tissue fixation for molecular profiling studies. Am J Pathol. 2002 Feb; 160(2):449-57. PMID: 11839565; PMCID: PMC1850633.
      Citations: 81     Fields:    Translation:Humans
    151. Traverso G, Shuber A, Levin B, Johnson C, Olsson L, Schoetz DJ, Hamilton SR, Boynton K, Kinzler KW, Vogelstein B. Detection of APC mutations in fecal DNA from patients with colorectal tumors. N Engl J Med. 2002 Jan 31; 346(5):311-20. PMID: 11821507.
      Citations: 56     Fields:    Translation:Humans
    152. Hamilton SR. Colon cancer testing and screening. Arch Pathol Lab Med. 1999 Nov; 123(11):1027-9. PMID: 10539901.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    153. Perucho M. Correspondence re: C.R. Boland et al., A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res., 58: 5248-5257, 1998. Cancer Res. 1999 Jan 01; 59(1):249-56. PMID: 9892214.
      Citations: 11     Fields:    Translation:HumansCells
    154. Chen PJ, Yeh SH, Chen DS. Alleles lost and gained in malignant cells. N Engl J Med. 1994 Dec 08; 331(23):1591-2. PMID: 7969336.
      Citations:    Fields:    Translation:HumansCells
    155. Nicolaides NC, Papadopoulos N, Liu B, Wei YF, Carter KC, Ruben SM, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature. 1994 Sep 01; 371(6492):75-80. PMID: 8072530.
      Citations: 328     Fields:    Translation:HumansCells
    156. Aaltonen LA, Mecklin JP, Jass JR, Green JS, Lynch HT, Watson P, Tallqvist G, Juhola M, Peltom?ki P, J?rvinen H, et al. Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res. 1994 Apr 01; 54(7):1645-8. PMID: 8137274.
      Citations: 152     Fields:    Translation:HumansCells
    157. Papadopoulos N, Nicolaides NC, Wei YF, Ruben SM, Carter KC, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, Adams MD, et al. Mutation of a mutL homolog in hereditary colon cancer. Science. 1994 Mar 18; 263(5153):1625-9. PMID: 8128251.
      Citations: 412     Fields:    Translation:HumansCells
    158. Leach FS, Nicolaides NC, Papadopoulos N, Liu B, Jen J, Parsons R, Sistonen P, Aaltonen LA, Peltom?ki P, Nystr?m-Lahti M, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell. 1993 Dec 17; 75(6):1215-25. PMID: 8261515.
      Citations: 459     Fields:    Translation:HumansAnimalsCells
    159. Aaltonen LA, Sistonen P, Mecklin JP, Green JS, Jass JR, Weber JL, Leach FS, Peltom?ki P, Pylkk?nen L, J?rvinen H, et al. Genetic mapping of a locus predisposing to human colorectal cancer. Science. 1993 May 07; 260(5109):810-2. PMID: 8484120.
      Citations: 166     Fields:    Translation:HumansCells
    160. Miyoshi Y, Ando H, Nagase H, Nishisho I, Horii A, Miki Y, Mori T, Utsunomiya J, Baba S, Petersen G, et al. Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proc Natl Acad Sci U S A. 1992 May 15; 89(10):4452-6. PMID: 1316610; PMCID: PMC49100.
      Citations: 153     Fields:    Translation:HumansCells
    161. Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S, Hedge P. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science. 1991 Aug 09; 253(5020):665-9. PMID: 1651563.
      Citations: 532     Fields:    Translation:HumansCells
    162. Hamilton SR. Reflux esophagitis and Barrett esophagus. Monogr Pathol. 1990; (31):11-68. PMID: 2406572.
      Citations: 1     Fields:    Translation:Humans
    163. Schneider PA, Hamilton SR, Dudgeon DL. Intestinal ischemic injury following mild hypothermic stress in the neonatal piglet. Pediatr Res. 1987 Apr; 21(4):422-5. PMID: 3574994.
      Citations: 4     Fields:    Translation:Animals
    164. Kanof ME, Rance NE, Hamilton SR, Luk GD, Lake AM. Congenital diarrhea with intestinal inflammation and epithelial immaturity. J Pediatr Gastroenterol Nutr. 1987 Jan-Feb; 6(1):141-6. PMID: 3794928.
      Citations: 2     Fields:    Translation:Humans
    165. Jones B, Fishman EK, Hamilton SR, Rubesin SE, Bayless TM, Cameron JC, Siegelman SS. Submucosal accumulation of fat in inflammatory bowel disease: CT/pathologic correlation. J Comput Assist Tomogr. 1986 Sep-Oct; 10(5):759-63. PMID: 3745545.
      Citations: 10     Fields:    Translation:Humans
    166. Greyson-Fleg RT, Jones B, Fishman EK, Hamilton SR, Siegelman SS. Computed tomography findings in gastrointestinal involvement by opportunistic organisms in acquired immune deficiency syndrome. J Comput Tomogr. 1986 Apr; 10(2):175-81. PMID: 3009090.
      Citations:    Fields:    Translation:Humans
    167. Fearon ER, Feinberg AP, Hamilton SH, Vogelstein B. Loss of genes on the short arm of chromosome 11 in bladder cancer. Nature. 1985 Nov 28-Dec 4; 318(6044):377-80. PMID: 2999610.
      Citations: 62     Fields:    Translation:Humans
    168. Ghory MJ, Pekcan M, Hebiguchi T, Hamilton SR, Dudgeon DL. A muscle ablation sphincter to prevent diarrhea after total colectomy in puppies: a preliminary report. J Pediatr Surg. 1985 Aug; 20(4):302-6. PMID: 4045653.
      Citations: 3     Fields:    Translation:Animals
    169. Yardley JH, Hamilton SR, Hutcheon DF. Endoscopic training in the academic GI program. Program Directors Workshop, March 29 and 30, 1984, Atlanta, Georgia. How the GI pathologist can interact best with the GI trainee. Gastrointest Endosc. 1984 Dec; 30(6):368-71. PMID: 6510650.
      Citations: 1     Fields:    
    170. Amano H, Hamilton SR, Bulkley GB. [Studies on the prediction of intestinal recovery from ischemic injury by fluorescein fluorescence patterns]. Nihon Geka Gakkai Zasshi. 1984 Jan; 85(1):56-64. PMID: 6738489.
      Citations:    Fields:    Translation:Animals
    171. White CL, Hamilton SR, Diamond MP, Cameron JL. Crohn's disease and ulcerative colitis in the same patient. Gut. 1983 Sep; 24(9):857-62. PMID: 6884819; PMCID: PMC1420082.
      Citations: 4     Fields:    Translation:Humans
    172. Walsh TJ, Hamilton SR. Disseminated aspergillosis complicating hepatic failure. Arch Intern Med. 1983 Jun; 143(6):1189-91. PMID: 6860047.
      Citations: 6     Fields:    Translation:Humans
    173. Hamilton SR. Pathologic features of Crohn's disease associated with recrudescence after resection. Pathol Annu. 1983; 18 Pt 1:191-203. PMID: 6348672.
      Citations: 2     Fields:    Translation:Humans
    174. Lake AM, Whitington PF, Hamilton SR. Dietary protein-induced colitis in breast-fed infants. J Pediatr. 1982 Dec; 101(6):906-10. PMID: 7143166.
      Citations: 36     Fields:    Translation:Humans
    175. Hamilton SR, Gupta PK, Marshall ME, Donovan PA, Wingard JR, Zaatari GS. Cerebrospinal fluid cytology in histiocytic proliferative disorders. Acta Cytol. 1982 Jan-Feb; 26(1):22-8. PMID: 6175126.
      Citations:    Fields:    Translation:Humans
    176. Hamilton SR, Keren DF, Yardley JH, Brown G. No impairment of local intestinal immune response to keyhole limpet haemocyanin in the absence of Peyer's patches. Immunology. 1981 Mar; 42(3):431-5. PMID: 7203530; PMCID: PMC1458454.
      Citations: 8     Fields:    Translation:Animals
    177. Zaatari GS, Hamilton SR, Jacobs J, Datiles TB. Comparison of nephelometry and immunofluorescence for immunoglobulin quantitation in pathologic sera. Clin Chim Acta. 1980 May 09; 103(3):357-66. PMID: 6772348.
      Citations:    Fields:    Translation:Humans
    178. Goodman ZD, Hamilton SR. Transient increase in serum creatine kinase isoenzyme BB activity after prostatectomy in a patient with massive benign prostatic hyperplasia. Clin Chem. 1980 Mar; 26(3):511-2. PMID: 6153944.
      Citations:    Fields:    Translation:Humans
    179. Cameron JL, McPhee SJ, Hamilton SR. Pancreatectomy and autotransplantation for chronic pancreatitis. Johns Hopkins Med J. 1979 Jun; 144(6):215-9. PMID: 110972.
      Citations:    Fields:    Translation:HumansAnimals
    180. Hamilton SR, Yardley JH, Brown GD. Suppression of local intestinal immunoglobulin A immune response to cholera toxin by subcutaneous administration of cholera toxoids. Infect Immun. 1979 May; 24(2):422-6. PMID: 457279; PMCID: PMC414318.
      Citations: 15     Fields:    
    181. Hamilton SR, Miller ME, Jessop M, Charache S. Comparison of microchromatography and electrophoresis with elution for hemoglobin A2 (Hb A2) quantitation. Am J Clin Pathol. 1979 Apr; 71(4):388-96. PMID: 443196.
      Citations:    Fields:    
    182. Yardley JH, Keren DF, Hamilton SR, Brown GD. Local (immunoglobulin A) immune response by the intestine to cholera toxin and its partial suppression with combined systemic and intra-intestinal immunization. Infect Immun. 1978 Feb; 19(2):589-97. PMID: 631891; PMCID: PMC414124.
      Citations: 20     Fields:    Translation:AnimalsPHPublic Health
    183. Intestinal ischemia following mild hypothermic stress in the neonatal piglet. Surgical Forum. VOL. 34:204-205.
    184. Phase II study of olaparib (AZD-2281) after standard systemic therapies for disseminated colorectal cancer. Oncologist. 21:172-177.
    185. Assessment of BRAF V600E status in colorectal carcinoma. Molecular Cancer Therapeutics. 14:2887-2895.
    186. Reply. Human Pathology. 19:1119-1120.
    187. Comment re. Cancer Prevention Research. 1:216.
    188. Acquisition of columnar (Barrett type) epithelium in the distal esophagus after partial esophagogastrectomy. Laboratory Investigation. 33:425-426.
    189. Reply. Human Pathology. 20:609.
    190. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability; Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Chemtracts. 12:708-713.
    191. Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proceedings of the National Academy of Sciences of the United States of America. 89:4457-4461.
    192. Regulation of AURKC expression by CpG island methylation in human cancer cells. Tumor Biology.
    193. Effects of chronic administration of meomycin on intestinal carcinogenesis in the azoxymethane (AOM)-treated-rat model. Gastroenterology. 80:1167.
    194. Lack of evidence for adenoma-carcinoma sequence in chemically induced colonic carcinogenesis in rats. Digestive Surgery. 2:143-151.
    195. Azoxymethane (AOM) induces a generalized biphasic increase in intestinal ornithine decarboxylase (ODC) during colon carcinogenesis. Gastroenterology. 82:1121.
    196. 2010 staging system for colon and rectal carcinoma. Annals of Surgical Oncology. 18:1513-1517.
    197. Clinical and Molecular Characteristics of Post-Colonoscopy Colorectal Cancer. Gastroenterology. 151:870-878.e3.
    198. Reduction of IgA and mucin in intestinal epithelium after exposure to cholera toxin. Federation Proceedings. 34.
    199. Endoscopic biopsy diagnosis of aspirin-associated chronic gastric ulcers. Gastroenterology. 78:1178.
    200. Sequential changes in colonic mucosal morphology and epithelial proliferation during chemically induced carcinogenesis in rats. Digestive Surgery. 5:99-108.
    201. Statistical considerations in the assessment of cDNA microarray data obtained using amplification. 21-36.
    202. The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis. Gut.
    203. Expression of p27(Kip1) and bcl-2, cigarette smoking, and colorectal cancer risk. Biomarkers. 5:225-234.
    204. Morphologic analogy of intestinal tract carcinogenesis in adenomatous polyposis and the azoxymethan-treated rat model. Laboratory Investigation. 46.
    205. Activity patterns of proteolytic enzymes - Relationship to neoplastic events during experimental carcinogenesis and preliminary results from colorectal tumor patients. Digestive Surgery. 7:156-163.
    206. N-acetylcysteine attenuates the cytoprotective effect of topical PGE2 in rat stomach. Gastroenterology. 82:1218.
    207. Inhibition and promotion of cancer of the colon by distal ileocolonic anastomosis in the azoxymethane-treated rat model. British Journal of Surgery. 68.
    208. Molecular triage trials in colorectal cancer. Cancer Journal (United States). 22:218-222.
    209. Obtaining reliable information from minute amounts of RNA using cDNA microarrays. BMC Genomics. 3.
    210. Malignant Tumors of the Colon. 1669-1716.
    211. MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer. Journal of Pathology. 241:67-79.
    212. Suppression of local intestinal IgA response to cholera toxin by subcutaneous priming and boosting with cholera toxoids. Gastroenterology. 74:1043.
    213. In Reply. Archives of Internal Medicine. 144:862.
    214. 'High-risk' and 'premalignant' lesions of the colon. American Journal of Surgical Pathology. 9:21-29.
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    216. Genetic/familial high-risk assessment. JNCCN Journal of the National Comprehensive Cancer Network. 14:1010-1030.
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