Item Type | Name |
Academic Article
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Treatment of Epstein-Barr virus-associated malignancies with specific T cells.
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Academic Article
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Immunotherapy for Hodgkin's disease.
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Academic Article
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Large-scale expansion of dendritic cell-primed polyclonal human cytotoxic T-lymphocyte lines using lymphoblastoid cell lines for adoptive immunotherapy.
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Academic Article
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Chronic active Epstein-Barr virus infection of natural killer cells presenting as severe skin reaction to mosquito bites.
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Academic Article
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Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic anemia.
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Academic Article
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The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease.
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Academic Article
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Immunotherapeutic options for Epstein-Barr virus-associated lymphoproliferative disease following transplantation.
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Academic Article
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Molecular transfer of CD40 and OX40 ligands to leukemic human B cells induces expansion of autologous tumor-reactive cytotoxic T lymphocytes.
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Academic Article
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T cells redirected against CD70 for the immunotherapy of CD70-positive malignancies.
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Academic Article
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Good manufacturing practice-grade cytotoxic T lymphocytes specific for latent membrane proteins (LMP)-1 and LMP2 for patients with Epstein-Barr virus-associated lymphoma.
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Academic Article
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Cellular immunotherapy for high-grade glioma.
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Academic Article
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Characterization and treatment of chronic active Epstein-Barr virus disease: a 28-year experience in the United States.
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Academic Article
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Expansion of T cells targeting multiple antigens of cytomegalovirus, Epstein-Barr virus and adenovirus to provide broad antiviral specificity after stem cell transplantation.
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Academic Article
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Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections.
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Academic Article
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Administration of latent membrane protein 2-specific cytotoxic T lymphocytes to patients with relapsed Epstein-Barr virus-positive lymphoma.
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Academic Article
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Targeting EBV's Achilles' heel with antigen-specific T cells.
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Academic Article
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Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs).
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Academic Article
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T cell therapies.
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Academic Article
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Contact-activated monocytes: efficient antigen presenting cells for the stimulation of antigen-specific T cells.
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Academic Article
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Dendritic cell function after gene transfer with adenovirus-calcium phosphate co-precipitates.
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Academic Article
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Regression of experimental medulloblastoma following transfer of HER2-specific T cells.
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Academic Article
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Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients.
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Academic Article
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Immunotherapy for osteosarcoma: genetic modification of T cells overcomes low levels of tumor antigen expression.
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Academic Article
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How to design effective vaccines: lessons from an old success story.
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Academic Article
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piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies.
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Academic Article
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HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors.
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Academic Article
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Adverse events following infusion of T cells for adoptive immunotherapy: a 10-year experience.
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Academic Article
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Crosstalk between medulloblastoma cells and endothelium triggers a strong chemotactic signal recruiting T lymphocytes to the tumor microenvironment.
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Academic Article
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IRAK-M removal counteracts dendritic cell vaccine deficits in migration and longevity.
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Academic Article
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Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma.
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Academic Article
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A Th1-inducing adenoviral vaccine for boosting adoptively transferred T cells.
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Academic Article
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Targeting of lysosomal acid phosphatase with altered carbohydrate.
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Academic Article
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T cells redirected to EphA2 for the immunotherapy of glioblastoma.
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Academic Article
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Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation.
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Academic Article
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PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor.
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Academic Article
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Cytotoxic T lymphocytes simultaneously targeting multiple tumor-associated antigens to treat EBV negative lymphoma.
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Academic Article
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Aggressive peripheral CD70-positive T-cell lymphoma associated with severe chronic active EBV infection.
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Academic Article
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Generation of polyclonal CMV-specific T cells for the adoptive immunotherapy of glioblastoma.
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Academic Article
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In vivo expansion of LMP 1- and 2-specific T-cells in a patient who received donor-derived EBV-specific T-cells after allogeneic stem cell transplantation.
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Academic Article
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Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer.
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Academic Article
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TILling head and neck cancer for cell therapy.
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Academic Article
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Interleukin-13 receptor a2: glioma's unlucky receptor?
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Concept
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Antigens, Differentiation, T-Lymphocyte
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Concept
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Lymphoma, T-Cell
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Concept
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Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
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Concept
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Hematopoietic Stem Cells
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
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Concept
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T-Lymphocytes, Cytotoxic
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Concept
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Receptors, Antigen, T-Cell
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Concept
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Neoplastic Stem Cells
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Concept
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T-Cell Antigen Receptor Specificity
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Concept
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Dendritic Cells
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Concept
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K562 Cells
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Concept
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Th1 Cells
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Concept
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CD8-Positive T-Lymphocytes
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Concept
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Endothelial Cells
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Concept
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CD4-Positive T-Lymphocytes
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Concept
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Killer Cells, Lymphokine-Activated
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Concept
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Antigen-Presenting Cells
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Concept
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Th2 Cells
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Concept
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B-Lymphocytes
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Concept
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T-Lymphocyte Subsets
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Concept
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Tumor Cells, Cultured
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Concept
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Epitopes, T-Lymphocyte
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Concept
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Lymphocytes, Tumor-Infiltrating
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Concept
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Bone Marrow Cells
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Concept
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Hep G2 Cells
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Concept
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Myeloid Cells
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Concept
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Killer Cells, Natural
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Concept
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Cells, Cultured
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Concept
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T-Lymphocytes
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Academic Article
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Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma.
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Academic Article
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Combinational targeting offsets antigen escape and enhances effector functions of adoptively transferred T cells in glioblastoma.
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Academic Article
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Adoptive T-cell transfer and chemotherapy in the first-line treatment of metastatic and/or locally recurrent nasopharyngeal carcinoma.
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Academic Article
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T-cell engager-armed oncolytic vaccinia virus significantly enhances antitumor therapy.
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Academic Article
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Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant.
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Academic Article
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Design and development of therapies using chimeric antigen receptor-expressing T cells.
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Academic Article
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A vaccine that co-targets tumor cells and cancer associated fibroblasts results in enhanced antitumor activity by inducing antigen spreading.
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Academic Article
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Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins.
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Academic Article
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CAR T cells for solid tumors: armed and ready to go?
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Academic Article
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Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity.
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Academic Article
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Genetically modified T cells to target glioblastoma.
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Academic Article
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Cell carriers to attack glioma.
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Academic Article
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Genetically modified T-cell therapy for osteosarcoma.
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Academic Article
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T cells redirected to interleukin-13Ra2 with interleukin-13 mutein--chimeric antigen receptors have anti-glioma activity but also recognize interleukin-13Ra1.
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Academic Article
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T-cell immunotherapy: looking forward.
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Academic Article
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Toward immunotherapy with redirected T cells in a large animal model: ex vivo activation, expansion, and genetic modification of canine T cells.
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Academic Article
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Engager T cells: a new class of antigen-specific T cells that redirect bystander T cells.
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Academic Article
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Adoptive cell therapy for sarcoma.
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Academic Article
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The narrow-spectrum HDAC inhibitor entinostat enhances NKG2D expression without NK cell toxicity, leading to enhanced recognition of cancer cells.
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Academic Article
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Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma.
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Academic Article
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Response to "in vivo secretion of anti-CD3 ? anti-tumor bispecific antibodies by gene-modified cells: over a decade of T-cell engagement".
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Academic Article
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Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Ra2-positive Glioma.
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Academic Article
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Adoptive T-Cell Immunotherapy.
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Academic Article
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T cells expressing CD19-specific Engager Molecules for the Immunotherapy of CD19-positive Malignancies.
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Academic Article
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Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape.
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Academic Article
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Redirecting T Cells to Glypican-3 with 4-1BB Zeta Chimeric Antigen Receptors Results in Th1 Polarization and Potent Antitumor Activity.
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Academic Article
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CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia.
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Academic Article
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Man's Best Friend: Utilizing Naturally Occurring Tumors in Dogs to Improve Chimeric Antigen Receptor T-cell Therapy for Human Cancers.
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Academic Article
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Genetically Modified T-cell Therapy for the Treatment of Osteosarcoma: An Update.
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Academic Article
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EBV-Directed T Cell Therapeutics for EBV-Associated Lymphomas.
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Academic Article
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Armed Oncolytic Adenovirus-Expressing PD-L1 Mini-Body Enhances Antitumor Effects of Chimeric Antigen Receptor T Cells in Solid Tumors.
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Academic Article
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HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial.
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Academic Article
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Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Ra2-CAR T Cells but Results in Antigen Loss Variants.
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Academic Article
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Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation.
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Academic Article
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Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models.
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Academic Article
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Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells.
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Academic Article
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CAR T-cell therapy for glioblastoma: ready for the next round of clinical testing?
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Academic Article
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Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma.
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Academic Article
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Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1.
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Academic Article
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Adenovirotherapy Delivering Cytokine and Checkpoint Inhibitor Augments CAR T Cells against Metastatic Head and Neck Cancer.
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Academic Article
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T Cell-Activating Mesenchymal Stem Cells as a Biotherapeutic for HCC.
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Academic Article
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Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma.
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Academic Article
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HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice.
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Academic Article
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Redirecting T cells to hematological malignancies with bispecific antibodies.
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Academic Article
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Advances in immunotherapy for pediatric acute myeloid leukemia.
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Academic Article
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CD28 and 41BB Costimulation Enhances the Effector Function of CD19-Specific Engager T Cells.
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Academic Article
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Adoptive Transfer of IL13Ra2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma.
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Academic Article
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Antibody with Infinite Affinity for In Vivo Tracking of Genetically Engineered Lymphocytes.
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Academic Article
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Epstein-Barr Virus (EBV)-derived BARF1 encodes CD4- and CD8-restricted epitopes as targets for T-cell immunotherapy.
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Academic Article
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The Landscape of CAR T Cells Beyond Acute Lymphoblastic Leukemia for Pediatric Solid Tumors.
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Academic Article
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NK Cells Expressing a Chimeric Activating Receptor Eliminate MDSCs and Rescue Impaired CAR-T Cell Activity against Solid Tumors.
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Academic Article
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Chimeric Antigen Receptor Signaling Domains Differentially Regulate Proliferation and Native T Cell Receptor Function in Virus-Specific T Cells.
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Grant
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Reprogramming of T cells for the Treatment of Melanoma
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Grant
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IL13Ra2 targeted T-cell therapy for glioma
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Grant
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Genetic Approaches to Optimize CAR T cells for Glioblastoma Therapy
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Grant
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Cancer and Stroma-Targeted Immunotherapy with a Gentically Modified DC Vaccine
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Academic Article
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EBV/LMP-specific T cells maintain remissions of T- and B-cell EBV lymphomas after allogeneic bone marrow transplantation.
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Academic Article
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Genetic Modification Strategies to Enhance CAR T Cell Persistence for Patients With Solid Tumors.
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Academic Article
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Peripheral T cell cytotoxicity predicts T cell function in the tumor microenvironment.
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Academic Article
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Engineering for Success: Approaches to Improve Chimeric Antigen Receptor T?Cell Therapy for Solid Tumors.
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Academic Article
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Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1.
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Concept
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A549 Cells
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Concept
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Myeloid-Derived Suppressor Cells
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Concept
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THP-1 Cells
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Concept
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HEK293 Cells
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Concept
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Neural Stem Cells
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Concept
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Human Umbilical Vein Endothelial Cells
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Academic Article
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Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape.
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Academic Article
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"Mini" bank of only 8 donors supplies CMV-directed T cells to diverse recipients.
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Academic Article
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Improved survival rate in T-cell depleted haploidentical hematopoietic cell transplantation over the last 15 years at a single institution.
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Academic Article
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Harnessing T Cells to Target Pediatric Acute Myeloid Leukemia: CARs, BiTEs, and Beyond.
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Academic Article
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Oncolytic Adenovirus Armed with BiTE, Cytokine, and Checkpoint Inhibitor Enables CAR T Cells to Control the Growth of Heterogeneous Tumors.
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Academic Article
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Genetically Modified T-Cell Therapy for Osteosarcoma: Into the Roaring 2020s.
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Academic Article
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Rewriting History: Epigenetic Reprogramming of CD8+ T Cell Differentiation to Enhance Immunotherapy.
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Academic Article
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Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma.
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Academic Article
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Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28? T Cells.
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Academic Article
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Preventing Ubiquitination Improves CAR T Cell Therapy via 'CAR Merry-Go-Around'.
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Academic Article
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Chimeric Antigen Receptor-modified T cells targeting EphA2 for the immunotherapy of paediatric bone tumours.
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Academic Article
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CAR T Cell Therapy for Solid Tumors: Bright Future or Dark Reality?
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Academic Article
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MyD88/CD40 signaling retains CAR T cells in a less differentiated state.
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Academic Article
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Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant.
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Academic Article
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Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery.
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Academic Article
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Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin.
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Academic Article
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Allogeneic CAR Cell Therapy-More Than a Pipe Dream.
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Academic Article
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A Chimeric GM-CSF/IL18 Receptor to Sustain CAR T-cell Function.
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Academic Article
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Engineering Oncolytic Vaccinia Virus to redirect Macrophages to Tumor Cells.
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Academic Article
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Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas.
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Academic Article
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Transient blockade of TBK1/IKKe allows efficient transduction of primary human natural killer cells with vesicular stomatitis virus G-pseudotyped lentiviral vectors.
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Academic Article
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Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape.
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Academic Article
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A Novel Orthotopic Implantation Technique for Osteosarcoma Produces Spontaneous Metastases and Illustrates Dose-Dependent Efficacy of B7-H3-CAR T Cells.
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Academic Article
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The role of exhaustion in CAR T cell therapy.
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Academic Article
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Hemophagocytic lymphohistiocytosis-like toxicity (carHLH) after CD19-specific CAR T-cell therapy.
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Academic Article
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CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity.
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Academic Article
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Cytolytic Activity of CAR T Cells and Maintenance of Their CD4+ Subset Is Critical for Optimal Antitumor Activity in Preclinical Solid Tumor Models.
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Academic Article
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Selectively targeting myeloid-derived suppressor cells through TRAIL receptor 2 to enhance the efficacy of CAR T cell therapy for treatment of breast cancer.
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Academic Article
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Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity.
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Academic Article
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Paediatric Strategy Forum for medicinal product development of chimeric antigen receptor T-cells in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
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Academic Article
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CD19-CAR T?cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia.
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Academic Article
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Unifying heterogeneous expression data to predict targets for CAR-T cell therapy.
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Academic Article
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Impact of High Disease Burden on Survival in Pediatric Patients with B-ALL Treated with Tisagenlecleucel.
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Academic Article
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Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells.
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Academic Article
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Employing Synthetic T-cell Biology to Target AML without On-Target/Off-Cancer Toxicity.
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Academic Article
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Donor-derived multiple leukemia antigen-specific T-cell therapy to prevent relapse after transplant?in patients with ALL.
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Academic Article
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CAR T cells redirected to cell surface GRP78 display robust anti-acute myeloid leukemia activity and do not target hematopoietic progenitor cells.
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Academic Article
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A Costimulatory CAR Improves TCR-based Cancer Immunotherapy.
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Academic Article
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B7-H3 Specific CAR T Cells for the Naturally Occurring, Spontaneous Canine Sarcoma Model.
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Academic Article
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Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL.
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Academic Article
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Transgenic Expression of IL15 Retains CD123-Redirected T Cells in a Less Differentiated State Resulting in Improved Anti-AML Activity in Autologous AML PDX Models.
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Academic Article
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CAR T?cell therapy for solid tumors: Fatal attraction requires adhesion.
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Academic Article
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Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages.
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Academic Article
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Improving the anti-acute myeloid leukemia activity of CD123-specific engager T cells by MyD88 and CD40 costimulation.
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Academic Article
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Engineering naturally occurring CD7- T cells for the immunotherapy of hematological malignancies.
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Academic Article
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Allogeneic CD34+ selected hematopoietic stem cell boost following CAR T-cell therapy in a patient with prolonged cytopenia and active infection.
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Academic Article
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CD47 expression is critical for CAR T-cell survival in vivo.
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Academic Article
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Terrific cells for SARS-CoV-2.
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Academic Article
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IL15 modification enables CAR T cells to act as a dual targeting agent against tumor cells and myeloid-derived suppressor cells in GBM.
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Academic Article
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A tour de force provides novel insights into CD19-CAR T?cell resistance mechanisms.
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Academic Article
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RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
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Academic Article
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Pre-existing immunity does not impair the engraftment of CRISPR-Cas9-edited cells in rhesus macaques conditioned with busulfan or radiation.
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Academic Article
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CAR T-cell design dependent remodeling of the brain tumor immune microenvironment identify macrophages as key players that inhibit or promote anti-tumor activity.
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Academic Article
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CD19 CAR T-cell therapy demonstrates activity against extramedullary disease in pediatric patients with B-ALL.
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Academic Article
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Preparation of cryopreserved chimeric antigen receptor T cells for the locoreogional delivery to the neural axis.
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Academic Article
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INSPIRED Symposium Part 4B: Chimeric Antigen Receptor T Cell Correlative Studies-Established Findings and Future Priorities.
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Academic Article
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Acute kidney injury following treatment with CD19-specific CAR T-cell therapy in children, adolescent and young adult patients with B-cell acute lymphoblastic leukemia.
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Academic Article
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Integrome signatures of lentiviral gene therapy for SCID-X1 patients.
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Academic Article
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Latent human herpesvirus 6 is reactivated in CAR T cells.
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Academic Article
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CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity.
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Academic Article
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Modular chimeric cytokine receptors with leucine zippers enhance the antitumour activity of CAR T cells via JAK/STAT signalling.
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Academic Article
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LILRB3 Modulates Acute Myeloid Leukemia Progression and Acts as an Effective Target for CAR T-cell Therapy.
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Academic Article
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Preventing relapse after CD19 CAR T-cell therapy for pediatric ALL: the role of transplant and enhanced CAR T cells.
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Academic Article
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Is immune escape in the rearview mirror?
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Academic Article
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Peptide-scFv antigen recognition domains effectively confer CAR T?cell multiantigen specificity.
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Academic Article
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DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T?cell responses that potentiate cell therapy for fibrolamellar carcinoma.
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Academic Article
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Acute kidney injury following treatment with CD19-specific CAR T-cell therapy in children, adolescent, and young adult patients with B-cell acute lymphoblastic leukemia.
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Academic Article
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Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication.
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