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ALLISON, JAMES P

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Item Type	Name
Academic Article	Epitope landscape in breast and colorectal cancer.
Concept	Antigen Presentation
Concept	CD11b Antigen
Concept	Receptors, Antigen, T-Cell, alpha-beta
Concept	Ki-67 Antigen
Concept	Receptors, Antigen, T-Cell
Concept	T-Cell Antigen Receptor Specificity
Concept	Lymphocyte Function-Associated Antigen-1
Concept	Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor
Concept	Antigen-Antibody Complex
Concept	Antigen-Antibody Reactions
Concept	Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Concept	Macrophage-1 Antigen
Concept	Antigen-Presenting Cells
Concept	Gene Rearrangement, delta-Chain T-Cell Antigen Receptor
Concept	B7-1 Antigen
Concept	Prostate-Specific Antigen
Concept	B7-2 Antigen
Concept	HLA-A2 Antigen
Concept	Receptors, Antigen, T-Cell, gamma-delta
Academic Article	Murine T cells with invariant gamma delta antigen receptors: origin, repertoire, and specificity.
Academic Article	The immunobiology of T cells with invariant gamma delta antigen receptors.
Academic Article	The congenic mutant B6.C-H-2bm-1 (H-2bm-1) serological response to the T-cell receptor on EL4.
Academic Article	The mouse T cell receptor: structural heterogeneity of molecules of normal T cells defined by xenoantiserum.
Academic Article	Biosynthesis and processing of murine T-cell antigen receptor.
Academic Article	Monoclonal antibody to chicken fetal antigens on normal erythroid cells and hematopoietic-lymphoid tumor cell lines.
Academic Article	T cell receptor-triggered activation of intraepithelial lymphocytes in vitro.
Academic Article	Itk negatively regulates induction of T cell proliferation by CD28 costimulation.
Academic Article	Cytotoxic T lymphocyte antigen-4 (CTLA-4) limits the expansion of encephalitogenic T cells in experimental autoimmune encephalomyelitis (EAE)-resistant BALB/c mice.
Academic Article	B7x: a widely expressed B7 family member that inhibits T cell activation.
Academic Article	Augmentation of T cell levels and responses induced by androgen deprivation.
Academic Article	Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer.
Academic Article	Restoring function in exhausted CD8 T cells during chronic viral infection.
Academic Article	Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function.
Academic Article	SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade.
Academic Article	CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion.
Academic Article	Serum-soluble B7x is elevated in renal cell carcinoma patients and is associated with advanced stage.
Academic Article	Tumor vaccines expressing flt3 ligand synergize with ctla-4 blockade to reject preimplanted tumors.
Academic Article	Optimization and validation of a robust human T-cell culture method for monitoring phenotypic and polyfunctional antigen-specific CD4 and CD8 T-cell responses.
Academic Article	Single dose of anti-CTLA-4 enhances CD8+ T-cell memory formation, function, and maintenance.
Academic Article	CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: three cases.
Academic Article	Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production.
Academic Article	Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy.
Academic Article	Expression of Helios in peripherally induced Foxp3+ regulatory T cells.
Academic Article	Immune modulation in cancer with antibodies.
Academic Article	Partial amino acid sequence of HLA-A9 antigen purified with a specific xenoantiserum.
Academic Article	Expression of a fetal gamma delta T-cell receptor in adult mice triggers a non-MHC-linked form of selective depletion.
Academic Article	Introduction: gamma delta T cells--the 'other' T lymphocytes.
Academic Article	The immunobiology of gamma delta+ T cells.
Academic Article	A subset of T cell receptors associated with L3T4 molecules mediates C6VL leukemia cell binding of its cognate retrovirus.
Academic Article	Structure, function, and serology of the T-cell antigen receptor complex.
Academic Article	Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells.
Academic Article	Diminished expression of the T cell receptor on the expanded lymphocyte population in MRL/Mp-lpr/lpr mice.
Academic Article	Limited diversity of gamma delta antigen receptor genes of Thy-1+ dendritic epidermal cells.
Academic Article	Gamma delta antigen receptors of Thy-1+ dendritic epidermal cells: implications for thymic differentiation.
Academic Article	The gamma T-cell antigen receptor.
Academic Article	Delta is the Cx-gene product in the gamma/delta antigen receptor of dendritic epidermal cells.
Academic Article	CD28-B7 interactions in T-cell activation.
Academic Article	Specificity and longevity of antitumor immune responses induced by B7-transfected tumors.
Academic Article	CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.
Academic Article	Characterization of neutrophils and T lymphocytes associated with the murine vaginal epithelium.
Academic Article	Activation and differentiation requirements of primary T cells in vitro.
Academic Article	Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage.
Academic Article	Manipulation of costimulatory signals to enhance antitumor T-cell responses.
Academic Article	T cell-mediated elimination of B7.2 transgenic B cells.
Academic Article	Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer.
Academic Article	CTLA-4: new insights into its biological function and use in tumor immunotherapy.
Academic Article	Prostate cancer: advances in immunotherapy.
Academic Article	PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells.
Academic Article	B7 expression on T cells down-regulates immune responses through CTLA-4 ligation via T-T interactions [corrections].
Academic Article	MHC class II-independent and -dependent T cell expansion and B cell hyperactivity in vivo in mice deficient in CD152 (CTLA-4).
Academic Article	Regulated costimulation in the thymus is critical for T cell development: dysregulated CD28 costimulation can bypass the pre-TCR checkpoint.
Academic Article	The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides. 1983.
Academic Article	Checkpoint blockade in cancer immunotherapy.
Academic Article	CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells.
Academic Article	The B7 family and cancer therapy: costimulation and coinhibition.
Academic Article	Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity.
Academic Article	Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies.
Academic Article	Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals.
Academic Article	Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas.
Academic Article	TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo.
Academic Article	Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab.
Academic Article	Response to "Ipilimumab (Yervoy) and the TGN1412 catastrophe".
Academic Article	Aire-dependent thymic development of tumor-associated regulatory T cells.
Academic Article	Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy.
Academic Article	An immune adsorption technique for analysis of antigenic determinants reacting with HLA antisera.
Academic Article	Human DR (Ia-like) antigens: biological and molecular profile.
Academic Article	Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors.
Academic Article	Molecular characterization of the murine T cell antigen receptor and associated structures.
Academic Article	Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors.
Academic Article	Antibodies against the T cell receptor/CD3 complex interfere with distinct intra-thymic cell-cell interactions in vivo: correlation with arrest of T cell differentiation.
Academic Article	Identification of antigen receptor-associated structures on murine T cells.
Academic Article	Limited diversity of T-cell receptor gamma-chain expression of murine Thy-1+ dendritic epidermal cells revealed by V gamma 3-specific monoclonal antibody.
Academic Article	Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes.
Academic Article	The murine T cell antigen receptor and associated structures.
Academic Article	Immunochemical characterization of differentiation and age-related cell surface antigens expressed by chicken erythrocytes.
Academic Article	Chicken fetal and adult antigen expression on erythroleukemia cells before and after induced differentiation.
Academic Article	T-cell activation: integration of signals from the antigen receptor and costimulatory molecules.
Academic Article	The role of short homology repeats and TdT in generation of the invariant gamma delta antigen receptor repertoire in the fetal thymus.
Academic Article	Co-stimulation via CD28 induces activation of a refractory subset of MRL-lpr/lpr T lymphocytes.
Academic Article	Co-stimulation in T cell responses.
Academic Article	The lymphoproliferative defect in CTLA-4-deficient mice is ameliorated by an inhibitory NK cell receptor.
Academic Article	BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1.
Academic Article	Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma.
Academic Article	CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems.
Academic Article	Emerging mechanisms of immune regulation: the extended B7 family and regulatory T cells.
Academic Article	Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody. 1982.
Academic Article	Co-stimulatory pathways in lymphocyte regulation: the immunoglobulin superfamily.
Academic Article	Principles and use of anti-CTLA4 antibody in human cancer immunotherapy.
Academic Article	CTLA-4 overexpression inhibits T cell responses through a CD28-B7-dependent mechanism.
Academic Article	A genetic library screen for signaling proteins that interact with phosphorylated T cell costimulatory receptors.
Academic Article	A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer.
Academic Article	Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of beta cells.
Academic Article	Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability.
Academic Article	B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome.
Academic Article	Recognition of a ubiquitous self antigen by prostate cancer-infiltrating CD8+ T lymphocytes.
Academic Article	Negative regulators of T-cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections.
Academic Article	Cancer immunotherapy: co-stimulatory agonists and co-inhibitory antagonists.
Academic Article	Inhibitors of B7-CD28 costimulation in urologic malignancies.
Academic Article	Attenuated T cell responses to a high-potency ligand in vivo.
Academic Article	Anti-CTLA-4 antibody therapy: immune monitoring during clinical development of a novel immunotherapy.
Academic Article	Strength of TCR-peptide/MHC interactions and in vivo T cell responses.
Academic Article	Tissue-specific expression of B7x protects from CD4 T cell-mediated autoimmunity.
Academic Article	Pillars article: CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. The journal of experimental medicine. 1995. 182: 459-465.
Academic Article	Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses.
Academic Article	Cutting edge: CTLA-4 on effector T cells inhibits in trans.
Academic Article	Cutting edge: chronic inflammatory liver disease in mice expressing a CD28-specific ligand.
Academic Article	Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4.
Academic Article	Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma.
Academic Article	Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy.
Academic Article	Gamma delta T cells in murine epithelia: origin, repertoire, and function.
Academic Article	Regulation of T-cell receptor gamma-chain RNA expression in murine Thy-1+ dendritic epidermal cells.
Academic Article	Alpha/beta T-cell antigen receptor gene and protein expression occurs at early stages of thymocyte differentiation.
Academic Article	The major histocompatibility complex-restricted antigen receptor on T cells in mouse and man: identification of constant and variable peptides.
Academic Article	Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients.
Academic Article	B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse.
Academic Article	Engagement of NKG2D by cognate ligand or antibody alone is insufficient to mediate costimulation of human and mouse CD8+ T cells.
Academic Article	Anti-cytotoxic T lymphocyte antigen-4 (CTLA-4) immunotherapy for the treatment of prostate cancer.
Academic Article	Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients.
Academic Article	Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy.
Academic Article	T cell surveillance of oncogene-induced prostate cancer is impeded by T cell-derived TGF-?1 cytokine.
Academic Article	Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model.
Academic Article	Intrathymic differentiation of V gamma 3 T cells.
Academic Article	Gamma delta T-cell development.
Academic Article	CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit.
Academic Article	Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial.
Academic Article	Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients.
Academic Article	Increased frequency of ICOS+ CD4 T cells as a pharmacodynamic biomarker for anti-CTLA-4 therapy.
Academic Article	Cytotoxic T lymphocyte antigen-4 blockade enhances antitumor immunity by stimulating melanoma-specific T-cell motility.
Academic Article	Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25.
Academic Article	Friends not foes: CTLA-4 blockade and mTOR inhibition cooperate during CD8+ T cell priming to promote memory formation and metabolic readiness.
Academic Article	The future of immune checkpoint therapy.
Academic Article	Ablation of B7-H3 but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer.
Academic Article	Strategies for combining immunotherapy with radiation for anticancer therapy.
Academic Article	Immune Checkpoint Blockade in Cancer Therapy: The 2015 Lasker-DeBakey Clinical Medical Research Award.
Academic Article	Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity.
Academic Article	The T-cell antigen receptor gamma gene
Academic Article	Biosynthesis of the murine T cell antigen receptor
Academic Article	Correlation of antigen receptor expression and surface phenotype of murine T-lymphomas
Academic Article	Molecular characterization of the murine T cell antigen receptor and associated structures
Academic Article	Effect of murine VÎ³3 and VÎ´1 antigen receptor transgenes on T cell development
Academic Article	B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality.
Academic Article	Checkpoints.
Academic Article	A conversation with James Allison.
Academic Article	Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
Academic Article	Interdependent IL-7 and IFN-? signalling in T-cell controls tumour eradication by combined a-CTLA-4+a-PD-1 therapy.
Academic Article	ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40-Mediated Tumor Rejection.
Academic Article	Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy.
Academic Article	Loss of IFN-? Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.
Academic Article	Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Academic Article	Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.
Academic Article	VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer.
Academic Article	Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity.
Academic Article	TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence.
Academic Article	Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade.
Academic Article	Robust Antitumor Responses Result from Local Chemotherapy and CTLA-4 Blockade.
Academic Article	Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy.
Academic Article	Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers.
Academic Article	Efficacy, Safety, and Biomarkers of Response to Azacitidine and Nivolumab in Relapsed/Refractory Acute Myeloid Leukemia: A Nonrandomized, Open-Label, Phase II Study.
Academic Article	Fundamental Mechanisms of Immune Checkpoint Blockade Therapy.
Academic Article	Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis.
Academic Article	Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer.
Academic Article	Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States.
Academic Article	TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion.
Concept	gp100 Melanoma Antigen
Concept	B7 Antigens
Concept	B7-H1 Antigen
Concept	CTLA-4 Antigen
Concept	Histocompatibility Antigen H-2D
Academic Article	Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients?
Academic Article	Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers-Response.
Academic Article	Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated Manner.
Academic Article	Combination anti-CTLA-4 plus anti-PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies.
Academic Article	Dissecting the mechanisms of immune checkpoint therapy.
Academic Article	Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma.
Academic Article	Pre-existing immune status associated with response to combination of sipuleucel-T and ipilimumab in patients with metastatic castration-resistant prostate cancer.
Academic Article	Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade.
Academic Article	Combined CTLA-4 and PD-L1 blockade in patients with chemotherapy-na?ve metastatic castration-resistant prostate cancer is associated with increased myeloid and neutrophil immune subsets in the bone microenvironment.
Academic Article	Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy.
Academic Article	Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma.
Academic Article	T cells specific for a-myosin drive immunotherapy-related myocarditis.
Academic Article	Immune checkpoint therapy-current perspectives and future directions.
Academic Article	The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?
Academic Article	ICOS costimulation in combination with CTLA-4 blockade remodels tumor-associated macrophages toward an antitumor phenotype.

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B7 Antigens