"Plaque, Amyloid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Accumulations of extracellularly deposited AMYLOID FIBRILS within tissues.
| Descriptor ID |
D058225
|
| MeSH Number(s) |
C23.300.821
|
| Concept/Terms |
Plaque, Amyloid- Plaque, Amyloid
- Amyloid Plaque
- Amyloid Plaques
- Plaques, Amyloid
- Amyloid Deposits
- Amyloid Deposit
- Deposit, Amyloid
- Deposits, Amyloid
Senile Plaques- Senile Plaques
- Plaque, Senile
- Plaques, Senile
- Senile Plaque
- Neuritic Plaques
- Neuritic Plaque
- Plaque, Neuritic
- Plaques, Neuritic
|
Below are MeSH descriptors whose meaning is more general than "Plaque, Amyloid".
Below are MeSH descriptors whose meaning is more specific than "Plaque, Amyloid".
This graph shows the total number of publications written about "Plaque, Amyloid" by people in this website by year, and whether "Plaque, Amyloid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 0 | 2 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 2 | 4 |
| 2016 | 2 | 0 | 2 |
| 2017 | 0 | 3 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 2 | 3 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 5 | 5 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Plaque, Amyloid" by people in Profiles.
-
Astrocytic Sox9 overexpression in Alzheimer's disease mouse models promotes A? plaque phagocytosis and preserves cognitive function. Nat Neurosci. 2026 Jan; 29(1):88-99.
-
Effects of SPI1-mediated transcriptome remodeling on Alzheimer's disease-related phenotypes in mouse models of A? amyloidosis. Nat Commun. 2024 May 11; 15(1):3996.
-
Genetic variants of phospholipase C-?2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease. Immunity. 2023 09 12; 56(9):2121-2136.e6.
-
Gantenerumab: an anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer's disease. Alzheimers Res Ther. 2022 11 29; 14(1):178.
-
Suppression of amyloid-? fibril growth by drug-engineered polymorph transformation. J Biol Chem. 2022 12; 298(12):102662.
-
Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials. JAMA Neurol. 2022 11 01; 79(11):1113-1121.
-
Targeting PSEN1 by lnc-CYP3A43-2/miR-29b-2-5p to Reduce ? Amyloid Plaque Formation and Improve Cognition Function. Int J Mol Sci. 2022 Sep 11; 23(18).
-
Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid ? plaques. Immunity. 2022 05 10; 55(5):879-894.e6.
-
Gene therapy using A? variants for amyloid reduction. Mol Ther. 2021 07 07; 29(7):2294-2307.
-
Pre-clinical dose-ranging efficacy, pharmacokinetics, tissue biodistribution, and toxicity of a targeted contrast agent for MRI of amyloid deposition in Alzheimer's disease. Sci Rep. 2020 09 30; 10(1):16185.