"TRPA1 Cation Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly conserved, non-selective TRP cation channel that contains 14-17 ANKYRIN REPEATS. It functions in cold sensation and NOCICEPTION of endogenous inflammatory factors and volatile irritants. TRPA1 is also activated by CANNABINOIDS and may play a role in sound perception by hair cells of the inner ear.
| Descriptor ID |
D000074025
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| MeSH Number(s) |
D12.776.157.530.400.901.250 D12.776.543.585.400.901.250
|
| Concept/Terms |
TRPA1 Cation Channel- TRPA1 Cation Channel
- Cation Channel, TRPA1
- Channel, TRPA1 Cation
- TRPA1 Channel
- Channel, TRPA1
- Transient Receptor Potential Cation Channel Subfamily A, Member 1
|
Below are MeSH descriptors whose meaning is more general than "TRPA1 Cation Channel".
Below are MeSH descriptors whose meaning is more specific than "TRPA1 Cation Channel".
This graph shows the total number of publications written about "TRPA1 Cation Channel" by people in this website by year, and whether "TRPA1 Cation Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "TRPA1 Cation Channel" by people in Profiles.
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Social deprivation induces astrocytic TRPA1-GABA suppression of hippocampal circuits. Neuron. 2023 04 19; 111(8):1301-1315.e5.
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Endogenous transient receptor potential ankyrin 1 and vanilloid 1 activity potentiates glutamatergic input to spinal lamina I neurons in inflammatory pain. J Neurochem. 2019 05; 149(3):381-398.
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Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance. Cancer Cell. 2018 06 11; 33(6):985-1003.e7.
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TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p. Nat Commun. 2017 10 16; 8(1):947.
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A Potent and Site-Selective Agonist of TRPA1. J Am Chem Soc. 2015 Dec 23; 137(50):15859-64.
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Dopamine is required for learning and forgetting in Drosophila. Neuron. 2012 May 10; 74(3):530-42.
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Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes. Am J Physiol Cell Physiol. 2006 Sep; 291(3):C424-32.