"DNA Demethylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Removal of methyl groups from DNA by enzymes (such as DIOXYGENASES and N-DEMETHYLASES) or by chemical reagents.
| Descriptor ID |
D000073399
|
| MeSH Number(s) |
G02.111.188.500.500 G02.607.141.500.500 G03.219.500.500
|
| Concept/Terms |
DNA Demethylation- DNA Demethylation
- DNA Demethylations
- Demethylation, DNA
- Demethylations, DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Demethylation".
Below are MeSH descriptors whose meaning is more specific than "DNA Demethylation".
This graph shows the total number of publications written about "DNA Demethylation" by people in this website by year, and whether "DNA Demethylation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA Demethylation" by people in Profiles.
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DNA demethylation in the hypothalamus promotes transcription of Agtr1a and Slc12a2 and hypertension development. J Biol Chem. 2024 Feb; 300(2):105597.
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Active DNA demethylation promotes cell fate specification and the DNA damage response. Science. 2022 12 02; 378(6623):983-989.
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Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development. Commun Biol. 2021 11 25; 4(1):1334.
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Population sequencing data reveal a compendium of mutational processes in the human germ line. Science. 2021 Aug 27; 373(6558):1030-1035.
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Regulatory Dynamics of Tet1 and Oct4 Resolve Stages of Global DNA Demethylation and Transcriptomic Changes in Reprogramming. Cell Rep. 2020 02 18; 30(7):2150-2169.e9.
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Delineation of a Human Mendelian Disorder of the DNA Demethylation Machinery: TET3 Deficiency. Am J Hum Genet. 2020 02 06; 106(2):234-245.
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Wnt-Induced Stabilization of KDM4C Is Required for Wnt/?-Catenin Target Gene Expression and Glioblastoma Tumorigenesis. Cancer Res. 2020 03 01; 80(5):1049-1063.
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Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development. Nat Commun. 2019 09 20; 10(1):4297.
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The Cell Type-Specific Expression of Lhcgr in Mouse Ovarian Cells: Evidence for a DNA-Demethylation-Dependent Mechanism. Endocrinology. 2018 05 01; 159(5):2062-2074.