"Kynurenine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
| Descriptor ID |
D007737
|
| MeSH Number(s) |
D12.125.608
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Kynurenine".
Below are MeSH descriptors whose meaning is more specific than "Kynurenine".
This graph shows the total number of publications written about "Kynurenine" by people in this website by year, and whether "Kynurenine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 3 | 0 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 2 | 4 |
| 2018 | 2 | 3 | 5 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 2 | 4 |
| 2021 | 1 | 3 | 4 |
| 2022 | 3 | 3 | 6 |
| 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "Kynurenine" by people in Profiles.
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Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion. Sci Adv. 2023 02 03; 9(5):eadd6995.
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Targeting Lin28 axis enhances glypican-3-CAR T?cell efficacy against hepatic tumor initiating cell population. Mol Ther. 2023 03 01; 31(3):715-728.
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Epacadostat Plus Pembrolizumab and Chemotherapy for Advanced Solid Tumors: Results from the Phase I/II ECHO-207/KEYNOTE-723 Study. Oncologist. 2022 11 03; 27(11):905-e848.
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Tryptophan oxidation in young children with environmental enteric dysfunction classified by the lactulose rhamnose ratio. Am J Clin Nutr. 2022 10 06; 116(4):970-979.
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Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry. J Immunother Cancer. 2022 07; 10(7).
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Age-Associated Gut Dysbiosis, Marked by Loss of Butyrogenic Potential, Correlates With Altered Plasma Tryptophan Metabolites in Older People Living With HIV. J Acquir Immune Defic Syndr. 2022 02 01; 89(Suppl 1):S56-S64.
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Peripheral and central kynurenine pathway abnormalities in major depression. Brain Behav Immun. 2022 03; 101:136-145.
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Tryptophan metabolites suppress the Wnt pathway and promote adverse limb events in chronic kidney disease. J Clin Invest. 2022 01 04; 132(1).
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Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKD. J Am Soc Nephrol. 2021 11; 32(11):2834-2850.
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Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies. Gut. 2022 06; 71(6):1095-1105.