"Alanine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
| Descriptor ID |
D000409
|
| MeSH Number(s) |
D12.125.042
|
| Concept/Terms |
Alanine- Alanine
- Alanine, L-Isomer
- Alanine, L Isomer
- L-Isomer Alanine
- L-Alanine
- L Alanine
|
Below are MeSH descriptors whose meaning is more general than "Alanine".
Below are MeSH descriptors whose meaning is more specific than "Alanine".
This graph shows the total number of publications written about "Alanine" by people in this website by year, and whether "Alanine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 2 | 3 |
| 1995 | 3 | 2 | 5 |
| 1996 | 1 | 2 | 3 |
| 1997 | 0 | 3 | 3 |
| 1998 | 0 | 5 | 5 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 7 | 7 |
| 2004 | 1 | 9 | 10 |
| 2005 | 0 | 6 | 6 |
| 2006 | 0 | 3 | 3 |
| 2007 | 1 | 9 | 10 |
| 2008 | 1 | 3 | 4 |
| 2009 | 2 | 6 | 8 |
| 2010 | 0 | 4 | 4 |
| 2011 | 1 | 0 | 1 |
| 2013 | 3 | 0 | 3 |
| 2014 | 2 | 2 | 4 |
| 2016 | 3 | 1 | 4 |
| 2017 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 3 | 12 | 15 |
| 2021 | 4 | 4 | 8 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 3 | 3 |
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click here.
Below are the most recent publications written about "Alanine" by people in Profiles.
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Pulsatile Leucine Administration during Continuous Enteral Feeding Enhances Skeletal Muscle Mechanistic Target of Rapamycin Complex 1 Signaling and Protein Synthesis in a Preterm Piglet Model. J Nutr. 2024 02; 154(2):505-515.
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Leptin Decreases Gluconeogenesis and Gluconeogenic Substrate Availability in Patients With Lipodystrophy. J Clin Endocrinol Metab. 2023 Dec 21; 109(1):e209-e215.
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Changes in local tissue microenvironment in response to subcutaneous long-acting delivery of tenofovir alafenamide in rats and non-human primates. J Control Release. 2023 06; 358:116-127.
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Regulation of skeletal muscle protein synthesis in the preterm pig by intermittent leucine pulses during continuous parenteral feeding. JPEN J Parenter Enteral Nutr. 2023 02; 47(2):276-286.
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Deconstructing the Treatment Effect of Remdesivir in the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1: Implications for Critical Care Resource Utilization. Clin Infect Dis. 2022 07 06; 74(12):2209-2217.
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Sites of vulnerability in HCV E1E2 identified by comprehensive functional screening. Cell Rep. 2022 05 24; 39(8):110859.
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Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial. Ann Intern Med. 2022 02; 175(2):234-243.
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Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial. Lancet Respir Med. 2021 12; 9(12):1365-1376.
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Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial. Intensive Care Med. 2021 11; 47(11):1258-1270.
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Single-Cell RNA Sequencing Supports Preferential Bioactivation of Remdesivir in the Liver. Antimicrob Agents Chemother. 2021 09 17; 65(10):e0133321.