"ERG1 Potassium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.
| Descriptor ID |
D000072237
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| MeSH Number(s) |
D12.776.157.530.400.600.900.249.500 D12.776.543.550.450.750.900.249.500 D12.776.543.585.400.750.900.249.500
|
| Concept/Terms |
ERG1 Potassium Channel- ERG1 Potassium Channel
- Channel, ERG1 Potassium
- Potassium Channel, ERG1
- Potassium Voltage-Gated Channel, Subfamily H, Member 2
- Ether-A-Go-Go-Related Potassium Channel 1
- Ether A Go Go Related Potassium Channel 1
Kv11.1 Protein-Potassium Channel- Kv11.1 Protein-Potassium Channel
- Channel, Kv11.1 Protein-Potassium
- Kv11.1 Protein Potassium Channel
- Protein-Potassium Channel, Kv11.1
|
Below are MeSH descriptors whose meaning is more general than "ERG1 Potassium Channel".
Below are MeSH descriptors whose meaning is more specific than "ERG1 Potassium Channel".
This graph shows the total number of publications written about "ERG1 Potassium Channel" by people in this website by year, and whether "ERG1 Potassium Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "ERG1 Potassium Channel" by people in Profiles.
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Sudden unexpected death in epilepsy genetics: Molecular diagnostics and prevention. Epilepsia. 2016 Jan; 57 Suppl 1:17-25.
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Genotype- and mutation site-specific QT adaptation during exercise, recovery, and postural changes in children with long-QT syndrome. Circ Arrhythm Electrophysiol. 2011 Dec; 4(6):867-73.
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Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nat Genet. 2009 Apr; 41(4):407-14.
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Structural determinants of potassium channel blockade and drug-induced arrhythmias. Handb Exp Pharmacol. 2006; (171):123-57.
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Compound mutations: a common cause of severe long-QT syndrome. Circulation. 2004 Apr 20; 109(15):1834-41.