"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
Descriptor ID |
D007108
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MeSH Number(s) |
G12.535.425
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 4 | 1 | 5 |
1995 | 3 | 1 | 4 |
1996 | 3 | 1 | 4 |
1997 | 1 | 2 | 3 |
1998 | 3 | 3 | 6 |
2000 | 4 | 4 | 8 |
2001 | 0 | 3 | 3 |
2002 | 7 | 2 | 9 |
2003 | 4 | 3 | 7 |
2004 | 1 | 4 | 5 |
2005 | 3 | 8 | 11 |
2006 | 4 | 5 | 9 |
2007 | 7 | 4 | 11 |
2008 | 6 | 4 | 10 |
2009 | 6 | 3 | 9 |
2010 | 8 | 6 | 14 |
2011 | 2 | 9 | 11 |
2012 | 3 | 4 | 7 |
2013 | 10 | 4 | 14 |
2014 | 2 | 4 | 6 |
2015 | 2 | 7 | 9 |
2016 | 3 | 5 | 8 |
2017 | 6 | 4 | 10 |
2018 | 3 | 2 | 5 |
2019 | 3 | 4 | 7 |
2020 | 3 | 4 | 7 |
2021 | 4 | 11 | 15 |
2022 | 0 | 4 | 4 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats. Nat Commun. 2022 12 26; 13(1):7951.
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Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy. Angiogenesis. 2023 05; 26(2):279-293.
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Responses of regulatory and effector T-cells to low-dose interleukin-2 differ depending on the immune environment after allogeneic stem cell transplantation. Front Immunol. 2022; 13:891925.
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Designing Clinical Trials for Combination Immunotherapy: A Framework for Glioblastoma. Clin Cancer Res. 2022 02 15; 28(4):585-593.
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The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1. Cancer Cell. 2022 01 10; 40(1):36-52.e9.
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9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy. Nat Commun. 2021 09 23; 12(1):5606.
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Immune Microenvironment Landscape in CNS Tumors and Role in Responses to Immunotherapy. Cells. 2021 08 09; 10(8).
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Gut Helminth Infection-Induced Immunotolerance and Consequences for Human Papillomavirus Persistence. Am J Trop Med Hyg. 2021 07 19; 105(3):573-583.
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Tolerance development in cow's milk-allergic infants receiving amino acid-based formula: A randomized controlled trial. J Allergy Clin Immunol. 2022 02; 149(2):650-658.e5.
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Reversing Post-Infectious Epigenetic-Mediated Immune Suppression. Front Immunol. 2021; 12:688132.