"Clonal Deletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. For T-lymphocytes this occurs in the thymus and ensures that mature T-lymphocytes are self tolerant. B-lymphocytes may also undergo clonal deletion.
| Descriptor ID |
D017637
|
| MeSH Number(s) |
G12.535.425.120
|
| Concept/Terms |
Clonal Deletion- Clonal Deletion
- Clonal Deletions
- Deletion, Clonal
- Deletions, Clonal
Clonal Abortion- Clonal Abortion
- Abortion, Clonal
- Abortions, Clonal
- Clonal Abortions
|
Below are MeSH descriptors whose meaning is more general than "Clonal Deletion".
Below are MeSH descriptors whose meaning is more specific than "Clonal Deletion".
This graph shows the total number of publications written about "Clonal Deletion" by people in this website by year, and whether "Clonal Deletion" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clonal Deletion" by people in Profiles.
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Peripheral apoptosis and limited clonal deletion during physiologic murine B lymphocyte development. Nat Commun. 2024 Jun 01; 15(1):4691.
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Impaired thymic negative selection causes autoimmune graft-versus-host disease. Blood. 2003 Jul 15; 102(2):429-35.
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Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs. J Clin Invest. 2001 Mar; 107(5):555-64.
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T cell-mediated elimination of B7.2 transgenic B cells. Immunity. 1997 Mar; 6(3):327-39.
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B cells are generated throughout life in humans. J Immunol. 1996 Jan 15; 156(2):866-72.