Ether-A-Go-Go Potassium Channels
"Ether-A-Go-Go Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of voltage-gated potassium channels that are characterized by long N-terminal and C-terminal intracellular tails. They are named from the Drosophila protein whose mutation causes abnormal leg shaking under ether anesthesia. Their activation kinetics are dependent on extracellular MAGNESIUM and PROTON concentration.
| Descriptor ID |
D051638
|
| MeSH Number(s) |
D12.776.157.530.400.600.900.249 D12.776.543.550.450.750.900.249 D12.776.543.585.400.750.900.249
|
| Concept/Terms |
Ether-A-Go-Go Potassium Channels- Ether-A-Go-Go Potassium Channels
- Ether A Go Go Potassium Channels
- Potassium Channels, Ether-A-Go-Go
- Eag-Related Potassium Channels
- Eag Related Potassium Channels
- Potassium Channels, Eag-Related
- Ether-A-Go-Go Related Potassium Channels
- Ether A Go Go Related Potassium Channels
- Eag Potassium Channels
- Potassium Channels, Eag
- ERG Potassium Channels
- Potassium Channels, ERG
|
Below are MeSH descriptors whose meaning is more general than "Ether-A-Go-Go Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Ether-A-Go-Go Potassium Channels".
This graph shows the total number of publications written about "Ether-A-Go-Go Potassium Channels" by people in this website by year, and whether "Ether-A-Go-Go Potassium Channels" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Ether-A-Go-Go Potassium Channels" by people in Profiles.
-
Use of high throughput ion channel profiling and statistical modeling to predict off-target arrhythmia risk - One pharma's experience and perspective. J Pharmacol Toxicol Methods. 2022 Nov-Dec; 118:107213.
-
ERG3 potassium channel-mediated suppression of neuronal intrinsic excitability and prevention of seizure generation in mice. J Physiol. 2018 10; 596(19):4729-4752.
-
Sudden unexpected death in epilepsy genetics: Molecular diagnostics and prevention. Epilepsia. 2016 Jan; 57 Suppl 1:17-25.
-
A critical assessment of combined ligand- and structure-based approaches to HERG channel blocker modeling. J Chem Inf Model. 2011 Nov 28; 51(11):2948-60.
-
Deletion of the potassium channel Kv12.2 causes hippocampal hyperexcitability and epilepsy. Nat Neurosci. 2010 Sep; 13(9):1056-8.
-
A Drosophila behavioral mutant, down and out (dao), is defective in an essential regulator of Erg potassium channels. Proc Natl Acad Sci U S A. 2010 Mar 23; 107(12):5617-21.
-
Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nat Genet. 2009 Apr; 41(4):407-14.
-
Structural determinants of potassium channel blockade and drug-induced arrhythmias. Handb Exp Pharmacol. 2006; (171):123-57.
-
Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation. Circulation. 2004 Oct 19; 110(16):2299-306.
-
A phase II trial comparing five dose levels of BEC2 anti-idiotypic monoclonal antibody vaccine that mimics GD3 ganglioside. Vaccine. 2004 Jul 29; 22(21-22):2904-9.