"Superoxide Dismutase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.
Descriptor ID |
D000072105
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MeSH Number(s) |
D08.811.682.881.500
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Concept/Terms |
Superoxide Dismutase-1- Superoxide Dismutase-1
- Cuprozinc Superoxide Dismutase
- Superoxide Dismutase, Cuprozinc
- Superoxide Dismutase 1
- Cu-Zn Superoxide Dismutase
- Cu Zn Superoxide Dismutase
- Superoxide Dismutase, Cu-Zn
- SOD-1 Protein
- SOD 1 Protein
- SOD1 Protein
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Below are MeSH descriptors whose meaning is more general than "Superoxide Dismutase-1".
Below are MeSH descriptors whose meaning is more specific than "Superoxide Dismutase-1".
This graph shows the total number of publications written about "Superoxide Dismutase-1" by people in this website by year, and whether "Superoxide Dismutase-1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 0 | 2 | 2 |
2012 | 0 | 5 | 5 |
2014 | 0 | 2 | 2 |
2016 | 1 | 1 | 2 |
2017 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Superoxide Dismutase-1" by people in Profiles.
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Mechanistic Insights of Astrocyte-Mediated Hyperactive Autophagy and Loss of Motor Neuron Function in SOD1L39R Linked Amyotrophic Lateral Sclerosis. Mol Neurobiol. 2020 Oct; 57(10):4117-4133.
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The relapsing fever spirochete Borrelia?turicatae persists in the highly oxidative environment of its soft-bodied tick vector. Cell Microbiol. 2019 02; 21(2):e12987.
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ALS patients' regulatory T lymphocytes are dysfunctional, and correlate with disease progression rate and severity. JCI Insight. 2017 03 09; 2(5):e89530.
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Reduced high-frequency motor neuron firing, EMG fractionation, and gait variability in awake walking ALS mice. Proc Natl Acad Sci U S A. 2016 11 22; 113(47):E7600-E7609.
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Neuronal overexpression of human VAPB slows motor impairment and neuromuscular denervation in a mouse model of ALS. Hum Mol Genet. 2016 11 01; 25(21):4661-4673.
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Administration of zinc complex of acetylsalicylic acid after the onset of myocardial injury protects the heart by upregulation of antioxidant enzymes. J Physiol Sci. 2016 Mar; 66(2):113-25.
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Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):E4568-76.
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Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection. J Clin Invest. 2014 Mar; 124(3):1255-67.
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Association of copper-zinc superoxide dismutase (SOD1) and manganese superoxide dismutase (SOD2) genes with nonsyndromic myelomeningocele. Birth Defects Res A Clin Mol Teratol. 2012 Oct; 94(10):762-9.
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Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD. Aging Cell. 2012 Oct; 11(5):770-82.