Stromal Interaction Molecule 1
"Stromal Interaction Molecule 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A stromal interaction molecule that functions in the regulation of calcium influx following depletion of intracellular calcium in the ENDOPLASMIC RETICULUM. It translocates to the plasma membrane upon calcium depletion where it activates the CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL ORAI1.
| Descriptor ID |
D000071737
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| MeSH Number(s) |
D12.776.157.125.806.500 D12.776.543.875.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Stromal Interaction Molecule 1".
Below are MeSH descriptors whose meaning is more specific than "Stromal Interaction Molecule 1".
This graph shows the total number of publications written about "Stromal Interaction Molecule 1" by people in this website by year, and whether "Stromal Interaction Molecule 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Stromal Interaction Molecule 1" by people in Profiles.
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Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat. Genes Immun. 2020 05; 21(3):182-192.
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Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca?? influx. Nat Cell Biol. 2015 Oct; 17(10):1339-47.
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Activation of the endoplasmic reticulum calcium sensor STIM1 and store-operated calcium entry by rotavirus requires NSP4 viroporin activity. J Virol. 2013 Dec; 87(24):13579-88.
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miR-195 competes with HuR to modulate stim1 mRNA stability and regulate cell migration. Nucleic Acids Res. 2013 Sep; 41(16):7905-19.
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Orai-STIM-mediated Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):E3539-48.
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Changes in plasma membrane Ca-ATPase and stromal interacting molecule 1 expression levels for Ca(2+) signaling in dystrophic mdx mouse muscle. Am J Physiol Cell Physiol. 2012 Sep 01; 303(5):C567-76.
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Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle. Am J Physiol Cell Physiol. 2010 Jul; 299(1):C42-50.